Abstract:
BACKGROUND AND PURPOSE:Declining trends in the incidence and mortality of stroke have been observed in Finland since the beginning of the 1980s until 1997. In this study we analyzed the trends in fatal and nonfatal strokes in Finland during 1991-2002. METHODS:The Finnish Hospital Discharge Register was linked to the National Causes of Death Register to produce a Cardiovascular Disease Register, which includes data on 410 760 cerebrovascular events (International Statistical Classification of Diseases, 10th Revision [ICD-10] codes I60-I69) in patients aged > or =35 years in 1991-2002. RESULTS:Age-standardized incidence of first-ever stroke (ICD-10 codes I60-I64, excluding I63.6) per 100 000 persons declined during 1991-2002 annually by 2.2% (95% CI, -2.4% to -1.9%) among men and 2.5% (-2.8% to -2.2%) among women aged 35 to 74 years. In patients aged 75 to 84 years, the change in the incidence of first-ever stroke was -2.6% per year (-3.0% to -2.2%) among men and -3.2% per year (-3.5% to -2.9%) among women. A similar trend was observed also in the oldest age group, in patients aged > or =85 years. Among patients aged 35 to 74 years, the 28-day case fatality of first-ever stroke declined annually by 3.2% (-3.9% to -2.5%) among men and by 3.0% (-3.8% to -2.2%) among women. A significant decrease was found in the 28-day case fatalities of all subtypes of stroke in this age group. CONCLUSIONS:The favorable development in stroke incidence, mortality, and case-fatality has continued in Finland during 1991-2002.
journal_name
Strokejournal_title
Strokeauthors
Pajunen P,Pääkkönen R,Hämäläinen H,Keskimäki I,Laatikainen T,Niemi M,Rintanen H,Salomaa Vdoi
10.1161/01.STR.0000152945.28543.4asubject
Has Abstractpub_date
2005-02-01 00:00:00pages
244-8issue
2eissn
0039-2499issn
1524-4628pii
01.STR.0000152945.28543.4ajournal_volume
36pub_type
杂志文章相关文献
STROKE文献大全abstract::Naloxone has been reported to have potential benefit in the treatment of stroke. We evaluated the effect of naloxone in a double-blind trial conducted with 15 stroke patients whose deficits ranged from 8 to 60 hours in duration. All but one patient sustained a cerebral infarction. Neurologic function was assessed befo...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.15.4.627
更新日期:1984-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Sonic hedgehog (Shh) protein is required for the maintenance of neural progenitor cells (NPCs) in the embryonic and adult hippocampus. Brain ischemia causes increased proliferation of hippocampal NPCs. We therefore examined whether Shh regulates the increase in proliferation of NPCs after ischemi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.561951
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Neutrophil Extracellular Traps (NETs) are DNA extracellular networks decorated with histones and granular proteins produced by activated neutrophils. NETs have been identified as major triggers and structural factors of thrombosis. A recent study designated extracellular DNA threads from NETs as ...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/STROKEAHA.117.019896
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral intraventricular infusion of acidic or basic fibroblast growth factor has been shown to attenuate ischemic damage to hippocampal CA1 neurons in the gerbil. The purpose of the present study was to determine if the basic fibroblast growth factor transgenic mouse has an enhanced ability to ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.11.1735
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:When carotid artery tandem lesions are present, the benefits of carotid endarterectomy (CEA) to reduce recurrent stroke remain uncertain. The present retrospective cohort study aimed to determine the clinical outcomes of CEA for carotid artery tandem stenosis that was diagnosed by contrast-enhanc...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.007181
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Using the dexamethasone suppression test, we studied the suppressibility of the cortisol axis and its clinical determinants at various time points after stroke. A major aim was to examine the dexamethasone test as a diagnostic tool for the diagnosis of major depression in stroke patients. METHOD...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.1.52
更新日期:1993-01-01 00:00:00
abstract::Of 564 consecutive patients with transient ischemic attack, 350 (62%) had cranial computed tomography performed. Except for date of admission and smoking history, there were few differences between the patients evaluated with computed tomography and the 214 who were not. Cerebral infarcts were found in 59 (17%) of the...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.4.431
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The independent contribution of insulin resistance to atherosclerosis is still under debate. We compared associations of 2 different indices of insulin resistance, the Homeostasis Model Assessment (HOMA) index and kITT from a short insulin tolerance test with carotid atherosclerosis. METHODS:A t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.502799
更新日期:2008-04-01 00:00:00
abstract::As part of a prospective study of the neurologic and neuropsychological complications of coronary artery bypass graft surgery, 312 patients were compared with a control group of 50 patients undergoing major surgery for peripheral vascular disease. The purpose of comparing the 2 groups was to determine to what extent n...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.4.700
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cannabidiol has been reported to be a neuroprotectant, but the neuroprotective mechanism of cannabidiol remains unclear. We studied the neuroprotective mechanism of cannabidiol in 4-hour middle cerebral artery (MCA) occlusion mice. METHODS:Male MCA occluded mice were treated with cannabidiol, ab...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000163083.59201.34
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Fish consumption has been postulated to reduce the risk of stroke. We conducted a dose-response meta-analysis to summarize the evidence from prospective studies regarding the association between fish consumption and stroke risk. METHODS:Pertinent studies were identified by searching Embase and P...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.111.630319
更新日期:2011-12-01 00:00:00
abstract::Acute cerebral circulatory changes following experimental cerebral hemorrhage were investigated in eight cats. The cerebral hemorrhage was produced in the right basal ganglia by introducing arterial blood via a thin catheter, using the systemic arterial blood pressure of the cat as a driving force. Local cerebral bloo...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.8.991
更新日期:1988-08-01 00:00:00
abstract::Background and Purpose- The ESCAPE trial (The Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) was a multicentre, randomized controlled trial of endovascular thrombectomy versus standard care for patients with acute ischemic strok...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.024096
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although lacunar stroke (LS) and deep intracerebral hemorrhage (dICH) represent acute manifestations of the same pathological process involving cerebral small vessels (small vessel disease), it remains unclear what factors predispose to one phenotype rather than the other at individual level. ME...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.013722
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Dipyridamole increases the concentration of circulating adenosine, which is a potent vasodilator, by inhibition of uptake of adenosine into the erythrocytes, and hence produces coronary vasodilation. However, the effects of dipyridamole on cerebral circulation is not pronounced. This study invest...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.8.1616
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Leukocytes have been implicated in the development of ischemic atherosclerotic vascular diseases. In a prospective study we investigated whether the plasma concentrations of inflammatory mediators, ie, proteases and cytokines, as markers for systemic leukocyte activation, are increased in patient...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.10.1734
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Central nervous system serotonergic neurotransmission appears to play a role in mood disorders, eating habits, and sleep, and also modulates blood pressure and metabolism. This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.106.477638
更新日期:2007-08-01 00:00:00
abstract::Background and Purpose- Depression and anxiety are common after stroke/transient ischemic attack (TIA). These conditions are associated with poor functional outcome and worse quality of life. However, few studies have explored predictors of poststroke risk of generalized anxiety, especially in patients without comorbi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.025464
更新日期:2019-09-01 00:00:00
abstract::In 100 consecutive patients with acute cerebrovascular accident, due to cerebral thrombosis in 72, cerebral hemorrhage in 12, embolus in 6, and subarachnoid hemorrhage in 10, there were 90 who had electrocardiographic abnormalities during the first three days after admission, compared to 50% in a control group. The pa...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.8.4.448
更新日期:1977-07-01 00:00:00
abstract::Intravenously injected metaraminol induced a larger blood pressure increase in spontaneously hypertensive rats (SHR) than in normotensive controls (NR) when the pressure was raised from the same starting level. Cerebral blood flow (CBF) response in NR was either perfect autoregulation, partial autoregulation or "break...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.10.5.572
更新日期:1979-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Early carotid surgery or stenting after thrombolytic treatment for stroke has become more common during recent years. It is unclear whether this carries an increased risk of postoperative complications and death. The aim of this nationwide population-based study was, therefore, to investigate the...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.003763
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Potassium channels are important regulators of resting tone in large cerebral arteries, but their activity and distribution may vary according to vessel location and species studied. In the cerebral microcirculation in vivo, however, these channels appear to be silent at rest. Our goal was to det...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.32.1.218
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Statin use may be associated with improved outcome in intracerebral hemorrhage patients. However, the topic remains controversial. Our analysis examined the effect of prior, continued, or new statin use on intracerebral hemorrhage outcomes using the ERICH (Ethnic/Racial Variations of Intracerebra...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.117.017358
更新日期:2017-08-01 00:00:00
abstract:UNLABELLED:The pathophysiology of postischemic encephalopathy is complex, and includes tissue acidosis, edema, hypoperfusion, membrane dysfunction, impaired energy production, and possibly hypermetabolism. We tested the hypothesis that this multifactorial clinical problem must be approached with multifaceted therapy, w...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.15.5.803
更新日期:1984-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We used Riks-Stroke, the Swedish Stroke Register, to explore how thrombolysis has been disseminated in Swedish hospitals since it was approved in 2003. METHODS:All 78 hospitals in Sweden admitting patients with acute stroke participate in Riks-Stroke. Between 2003 and 2008, 72 033 adult patients...
journal_title:Stroke
pub_type: 杂志文章,多中心研究
doi:10.1161/STROKEAHA.109.577106
更新日期:2010-06-01 00:00:00
abstract::The effect of cigarette smoking on extracranial carotid atherosclerosis was studies by obtaining cigarette smoking histories and information on other potential risk factors from consecutive patients undergoing carotid arteriography. At least on extracranial carotid artery was visualized in 752 patients in whom the ext...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.5.707
更新日期:1990-05-01 00:00:00
abstract::The occurrence of epileptic seizures was investigated in 141 patients with angiographically proven carotid or MCA occlusive disease. Epileptic seizures occurred some time during the clinical course of the disease in 17.3% of carotid patients and in 10.8% of MCA patients, being mainly represented by partial motor seizu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.13.2.189
更新日期:1982-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although the stroke rate associated with atrial fibrillation has declined over the last 10 years, the emerging atrial fibrillation epidemic threatens to increase the incidence of cardioembolic stroke. Summary of Review-Oral anticoagulants are superior antithrombotic agents but are underused due t...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/STROKEAHA.110.589218
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.120.029454
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Reliable data on the risk of carotid endarterectomy (CEA) in relation to clinical indication and timing of surgery are necessary to target CEA more effectively, to inform patients, to adjust risks for case mix, and to understand the mechanisms of operative stroke. METHODS:We performed a systemat...
journal_title:Stroke
pub_type: 杂志文章,meta分析,评审
doi:10.1161/01.STR.0000087785.01407.CC
更新日期:2003-09-01 00:00:00