MRI-based separation of congenital and acquired vertebrobasilar artery anomalies in ischemic stroke of the posterior circulation.

abstract：BACKGROUND AND PURPOSE:Three-dimensional pseudocontinuous arterial spin labeling with multiple postlabeling delays has been used to assess cerebral blood flow (CBF). We used this modality to estimate antegrade and collateral flow in patients with unilateral middle cerebral artery stenosis. METHODS:Consecutive patients...

journal_title：Stroke

authors： Lyu J,Ma N,Liebeskind DS,Wang DJ,Ma L,Xu Y,Wang T,Miao Z,Lou X

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Using the dexamethasone suppression test, we studied the suppressibility of the cortisol axis and its clinical determinants at various time points after stroke. A major aim was to examine the dexamethasone test as a diagnostic tool for the diagnosis of major depression in stroke patients. METHOD...

journal_title：Stroke

authors： Aström M,Olsson T,Asplund K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:[18F]fluoromisonidazole (FMISO) positron emission tomography has been used to image hypoxia early after human stroke. To further study the role of hypoxia in stroke and the binding characteristics of FMISO, we aimed to develop [3H]FMISO autoradiography in an animal stroke model. We hypothesized t...

journal_title：Stroke

authors： Spratt NJ,Ackerman U,Tochon-Danguy HJ,Donnan GA,Howells DW

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent studies have shown that the cerebral arteriolar dilation from hypercapnic acidosis is blocked by agents which inhibit KATP channels. These findings suggested that this response is due to opening of KATP channels. Because the repose to CO2 is a continuum, with hypercapnic acidosis causing v...

journal_title：Stroke

authors： Wei EP,Kontos HA

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been recently shown to play a significant role in the propagation of CSD. However, the intracellu...

journal_title：Stroke

authors： Liu L,Kearns KN,Eli I,Sharifi KA,Soldozy S,Carlson EW,Scott KW,Sluzewski MF,Acton ST,Stauderman KA,Kalani MYS,Park M,Tvrdik P

更新日期：2021-01-01 00:00:00

abstract：:Ischemia due to middle cerebral artery occlusion was studied in 29 rats from 1 to 24 hours after occlusion using magnetic resonance imaging. Images were made before and after the injection of a superparamagnetic iron oxide compound, AMI-25. Subtraction images demonstrated the region of perfusion deficit as early as 1 ...

journal_title：Stroke

authors： Bradley RH,Kent TA,Eisenberg HM,Quast MJ,Ward GA,Campbell GA,Hillman G

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Choroid plexus (CP) secretes a cocktail of neurotrophic factors. In the present study, CP from neonatal pigs was encapsulated within alginate microcapsules for in vitro and in vivo neuroprotective studies. METHODS:In vitro studies involved serum deprivation of rat embryonic cortical neurons and ...

journal_title：Stroke

authors： Borlongan CV,Skinner SJ,Geaney M,Vasconcellos AV,Elliott RB,Emerich DF

更新日期：2004-09-01 00:00:00

abstract：:To clarify the nature of ischemic striatal dopamine release during the earliest periods of neuronal injury, we used chronoamperometry to measure dopamine levels every 60 seconds during various durations of ischemia in 32 gerbils. Catecholamine-selective electrodes were implanted into the brains of anesthetized gerbils...

journal_title：Stroke

authors： Ahn SS,Blaha CD,Alkire MT,Wood E,Gray-Allan P,Marrocco RT,Moore WS

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The efficacy of neuroprotective approaches in stroke may be influenced by existing comorbidities. Here, we compared the effects of normobaric hyperoxia (NBO) in normotensive versus hypertensive rats subjected to transient focal cerebral ischemia. METHODS:Male Sprague-Dawley and spontaneously hyp...

journal_title：Stroke

authors： Lan J,Esposito E,Ayata C,Singhal AB,Lo EH,Ji X

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Impaired rheological properties of as well as cytotoxic substances produced by granulocytes may contribute to tissue damage in acute ischemic stroke. To assess changes in the properties of circulating granulocytes, we measured their adhesion, deformability, and superoxide generation in the first ...

journal_title：Stroke

authors： Grau AJ,Berger E,Sung KL,Schmid-Schönbein GW

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke leads to a reduction in bone mineral density, altered calcium homeostasis, and an increase in hip fractures. Vitamin D deficiency is well documented in long-term stroke survivors and is associated with post-stroke hip fractures. Less is known regarding levels in acute stroke. METHODS:We c...

journal_title：Stroke

authors： Poole KE,Loveridge N,Barker PJ,Halsall DJ,Rose C,Reeve J,Warburton EA

更新日期：2006-01-01 00:00:00

abstract：:Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a co...

journal_title：Stroke

authors： Dichgans M,Planas AM,Biessels GJ,van der Worp B,Sudlow C,Norrving B,Lees K,Mattle HP

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There have been relatively few community-based studies of long-term prognosis after acute stroke. This study aimed to provide precise estimates of the absolute and relative risks of dying in an unselected cohort of patients with a first-ever stroke. METHODS:Six hundred seventy-five patients were...

journal_title：Stroke

authors： Dennis MS,Burn JP,Sandercock PA,Bamford JM,Wade DT,Warlow CP

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Urinary incontinence in the acute stage of stroke is seen as a predictor of death, severe disability, and an important factor on hospital discharge destination. Therefore, it is an important measure of stroke severity that not only affects the lives of stroke survivors but also those of caregivers. SUMMARY ...

journal_title：Stroke

authors： Brittain KR,Peet SM,Castleden CM

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A ruptured intracranial aneurysm (IA) is the leading cause of a subarachnoid hemorrhage. This study seeks to define a specific gene whose mutation leads to disease. METHODS:More than 500 IA probands and 100 affected families were enrolled and clinically characterized. Whole exome sequencing was ...

journal_title：Stroke

authors： Santiago-Sim T,Fang X,Hennessy ML,Nalbach SV,DePalma SR,Lee MS,Greenway SC,McDonough B,Hergenroeder GW,Patek KJ,Colosimo SM,Qualmann KJ,Hagan JP,Milewicz DM,MacRae CA,Dymecki SM,Seidman CE,Seidman JG,Kim DH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The neuroprotective efficacy of an intravenous formulation of the antioxidant ebselen has been comprehensively assessed with specific regard to conventional quantitative histopathology, subcortical axonal damage, neurological deficit, and principal mechanism of action. METHODS:Transient focal is...

journal_title：Stroke

authors： Imai H,Masayasu H,Dewar D,Graham DI,Macrae IM

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Current guidelines recommend against routine auscultation of carotid arteries, believing that carotid bruits are poor predictors of either underlying carotid stenosis or stroke risk in asymptomatic patients. We investigated whether the presence of a carotid bruit is associated with increased risk...

journal_title：Stroke

authors： Pickett CA,Jackson JL,Hemann BA,Atwood JE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The majority of ischemic stroke patients receiving endovascular recanalization therapy (EVT) experience variable changes of neurological severities during the hyperacute period. We hypothesized that the National Institutes of Health Stroke Scale (NIHSS) score after EVT is a better prognostic fact...

journal_title：Stroke

authors： Jeong HG,Kim BJ,Choi JC,Hong KS,Yang MH,Jung C,Han MK,Bae HJ

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Mechanisms involved in stroke progression are incompletely understood. Ischemic brain injury is characterized by acute local inflammatory response mediated by cytokines. Anti-inflammatory cytokines act in a feedback loop to inhibit continued proinflammatory cytokine production. We assessed the implication of...

journal_title：Stroke

authors： Vila N,Castillo J,Dávalos A,Esteve A,Planas AM,Chamorro A

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Redundant internal carotid arteries have been considered a risk factor in tonsillectomy, adenoidectomy, and surgical treatment of peritonsillar abscess and also a potentially treatable cause of stroke. However, an association between internal carotid artery redundancy and spontaneous dissection h...

journal_title：Stroke

authors： Barbour PJ,Castaldo JE,Rae-Grant AD,Gee W,Reed JF 3rd,Jenny D,Longennecker J

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The perfusion territories of the brain-feeding arteries are difficult to assess in vivo and therefore standard cerebral perfusion territory templates are often used to determine the relation between cerebral infarcts and the feeding vasculature. In the present study, we compared this infarct clas...

journal_title：Stroke

authors： Hendrikse J,Petersen ET,Chèze A,Chng SM,Venketasubramanian N,Golay X

更新日期：2009-05-01 00:00:00

abstract：:The nature of alpha-adrenergic receptors in human cerebral arteries was characterized, and alteration of these receptors after subarachnoid hemorrhage was examined using a radioligand binding assay. Norepinephrine content of control arteries was also analyzed and compared with that of arteries after subarachnoid hemor...

journal_title：Stroke

authors： Tsukahara T,Taniguchi T,Miwa S,Shimohama S,Fujiwara M,Nishikawa M,Handa H

更新日期：1988-01-01 00:00:00

abstract：:Moyamoya is an intriguing and controversial syndrome. This patient study serves to align the pathophysiology of intracranial hemorrhage in moyamoya with the cerebral vascular disease seen with hypertension, or aging. The historical evidence linking lipohyalinosis and microaneurysms to cerebral hemorrhage is reviewed, ...

journal_title：Stroke

authors： Mauro AJ,Johnson ES,Chikos PM,Alvord EC Jr

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Collateral flow augmentation using partial aortic occlusion may improve cerebral perfusion in acute stroke. We assessed the safety and feasibility of partial aortic occlusion immediately after intravenous tissue plasminogen activator. METHODS:We conducted an open-label pilot study of partial aor...

journal_title：Stroke

authors： Emery DJ,Schellinger PD,Selchen D,Douen AG,Chan R,Shuaib A,Butcher KS

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron is an essential element for the human body. It has, however, been suggested that excessive iron stores may increase the risk of vascular disease. So far, epidemiologic studies on stroke are sparse. METHODS:We studied the association between iron status and stroke risk in a population-based ...

journal_title：Stroke

authors： van der A DL,Grobbee DE,Roest M,Marx JJ,Voorbij HA,van der Schouw YT

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We assessed the influence of different visual stimuli and the reproducibility and habituation of evoked flow responses using simultaneous two-channel transcranial Doppler monitoring and flow velocity averaging. METHODS:We measured stimulus-related percentage changes in posterior cerebral, basila...

journal_title：Stroke

authors： Sturzenegger M,Newell DW,Aaslid R

更新日期：1996-12-01 00:00:00

abstract：:Background and Purpose- High-resolution vessel wall magnetic resonance imaging is a promising technique for assessing wall structures of unruptured intracranial aneurysms (UIAs). However, the relationship between aneurysmal high-resolution vessel wall magnetic resonance imaging features and their histopathologic mecha...

journal_title：Stroke

authors： Quan K,Song J,Yang Z,Wang D,An Q,Huang L,Liu P,Li P,Tian Y,Zhou L,Zhu W

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We designed a prospective sequential pretreatment and posttreatment MRI study to assess the relation between neuroimaging parameters and clinical outcome in patients treated with intravenous recombinant tissue-type plasminogen activator (rtPA). METHODS:Patients with symptoms of acute hemispheric...

journal_title：Stroke

authors： Nighoghossian N,Hermier M,Adeleine P,Derex L,Dugor JF,Philippeau F,Ylmaz H,Honnorat J,Dardel P,Berthezène Y,Froment JC,Trouillas P

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cancer is a risk factor for ischemic stroke. Little is known about cancer among young adults with ischemic stroke. We studied the frequency of cancer and its association with long-term risk of death among young patients with first-ever ischemic stroke. METHODS:1002 patients aged 15 to 49 years, ...

journal_title：Stroke

authors： Aarnio K,Joensuu H,Haapaniemi E,Melkas S,Kaste M,Tatlisumak T,Putaala J

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The *2 allele of the aldehyde dehydrogenase 2 gene (ALDH2) is the most common variant in Asian populations. The variant resulting in enzyme dysfunction was highly related to coronary artery disease. Recently, genome-wide association studies also discovered that the 12q24 locus near ALDH2 gene was...

journal_title：Stroke

authors： Sung YF,Lu CC,Lee JT,Hung YJ,Hu CJ,Jeng JS,Chiou HY,Peng GS

更新日期：2016-09-01 00:00:00