Late-phase contrast-enhanced ultrasound reflects biological features of instability in human carotid atherosclerosis.

abstract：BACKGROUND AND PURPOSE:Inflammatory mechanisms can exacerbate ischemic tissue damage and worsen clinical outcome in patients with stroke. Both αβ and γδ T cells are established mediators of tissue damage in stroke, and the role of dendritic cells (DCs) in inducing the early events of T cell activation and differentiati...

journal_title：Stroke

authors： Gelderblom M,Gallizioli M,Ludewig P,Thom V,Arunachalam P,Rissiek B,Bernreuther C,Glatzel M,Korn T,Arumugam TV,Sedlacik J,Gerloff C,Tolosa E,Planas AM,Magnus T

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to investigate the relationship between early NT-proBNP (N-terminal probrain natriuretic peptide) and all-cause death in patients receiving reperfusion therapy, including intravenous thrombolysis and endovascular thrombectomy (EVT). METHODS:This study included 1039 acute ischemic stroke...

journal_title：Stroke

authors： Zhang X,Yan S,Zhong W,Yu Y,Lou M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral sinovenous thrombosis is a rare disease with severe neurological sequelae. The aim of this retrospective multicenter study was to investigate the clinical course, possible risk factors, and outcome of a cohort of neonatal patients with sinovenous thrombosis and, second, to estimate the i...

journal_title：Stroke

authors： Berfelo FJ,Kersbergen KJ,van Ommen CH,Govaert P,van Straaten HL,Poll-The BT,van Wezel-Meijler G,Vermeulen RJ,Groenendaal F,de Vries LS,de Haan TR

更新日期：2010-07-01 00:00:00

abstract：:The effects of hypoxic hypoxia on cerebral hemodynamics and somatosensory evoked potential (SEP) were studied in 10 pentobarbital anestheteized dogs. Cerebral blood flow (CBF) was measured using the venous outflow technique and cerebral oxygen consumption (CMRO2) was calculated from the arterio-cerebro-venous oxygen d...

journal_title：Stroke

authors： McPherson RW,Zeger S,Traystman RJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis for acute ischemic stroke is usually based on clinical assessment, blood test results, and CT findings. Intravenous thrombolysis of stroke mimics may occur but has not been studied in detail. METHODS:We determined frequency, clinical characteristics, and outcome of mimic...

journal_title：Stroke

authors： Winkler DT,Fluri F,Fuhr P,Wetzel SG,Lyrer PA,Ruegg S,Engelter ST

更新日期：2009-04-01 00:00:00

abstract：:We used 44 splenectomized dogs to study the effects of isovolemic hemodilution with a crystalloid solution. The dogs were randomly divided into a hemodilution and a control group. In each group, 17 dogs were subjected to 6 hours of internal carotid and middle cerebral artery occlusion, and five dogs received sham oper...

journal_title：Stroke

authors： Hyodo A,Heros RC,Tu YK,Ogilvy C,Graichen R,Lagree K,Korosue K

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:beta-Blockers prevent vascular events in patients after myocardial infarction and lower blood pressure, the main risk factor for stroke. Hence, we assessed the effects of atenolol on the occurrence of death from vascular causes, stroke, or myocardial infarction and on blood pressure in patients a...

journal_title：Stroke

authors：

更新日期：1993-04-01 00:00:00

abstract：:Background and Purpose- Cerebral small vessel disease (SVD) is associated with increased stroke risk and poor stroke outcomes. We aimed to evaluate whether chronic SVD burden is associated with poor recruitment of collaterals in large-vessel occlusive stroke. Methods- Consecutive patients with middle cerebral artery o...

journal_title：Stroke

authors： Lin MP,Brott TG,Liebeskind DS,Meschia JF,Sam K,Gottesman RF

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease. Variation in the levels of this amino acid has been shown to be due to nutritional status and methylenetetrahydrofolate reductase (MTHFR) genotype. METHODS:Under a case-cont...

journal_title：Stroke

authors： McIlroy SP,Dynan KB,Lawson JT,Patterson CC,Passmore AP

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The CHA2DS2-VASc stroke score (congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65-74, female) is used in most guidelines for risk stratification in atrial fibrillation (AF), but most data for ...

journal_title：Stroke

authors： Kim TH,Yang PS,Uhm JS,Kim JY,Pak HN,Lee MH,Joung B,Lip GYH

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The CHADS(2) score is used for risk stratification of ischemic stroke in patients with nonvalvular atrial fibrillation and high CHADS(2) scores are associated with increased risk of stroke. Most components of the CHADS(2) score are also risk factors for atherosclerosis. Therefore, high CHADS(2) s...

journal_title：Stroke

authors： Kim YD,Cha MJ,Kim J,Lee DH,Lee HS,Nam CM,Nam HS,Heo JH

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It was found that glutamate, a major neurotransmitter, is vasoactive in the cerebral circulation. However, the mechanism is unclear. This study was designed to investigate the role of nitric oxide (NO) and N-methyl-D-aspartate (NMDA) receptors in cerebral arteriolar dilation to glutamate. METHOD...

journal_title：Stroke

authors： Meng W,Tobin JR,Busija DW

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Disturbed cerebral autoregulation has been reported to correlate with an unfavorable outcome after head injury. Using transcranial Doppler ultrasonography, we investigated whether hemodynamic responses to spontaneous variations of cerebral perfusion pressure (CPP) provide reliable information on ...

journal_title：Stroke

authors： Czosnyka M,Smielewski P,Kirkpatrick P,Menon DK,Pickard JD

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to determine the incidence of adult cerebral venous thrombosis. METHODS:A retrospective cross-sectional study was conducted among all 19 hospitals located in 2 Dutch provinces serving 3.1 million people. Adult cerebral venous thrombosis cases diagnosed between Janua...

journal_title：Stroke

authors： Coutinho JM,Zuurbier SM,Aramideh M,Stam J

更新日期：2012-12-01 00:00:00

abstract：:The study of focal central nervous system ischemia has been impeded by the lack of animal models that are both reproducible and simulate human ischemic strokes. To circumvent these problems, we have developed a rabbit spinal cord infarction model. Infarction of the caudal lumbar cord is produced by temporary occlusion...

journal_title：Stroke

authors： Zivin JA,DeGirolami U

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The underlying mechanisms for reductions in cerebral blood flow (CBF) during orthostasis are not completely understood. This study tested the hypothesis that sympathetic activation causes cerebral vasoconstriction leading to reductions in CBF during lower body negative pressure (LBNP). METHODS:C...

journal_title：Stroke

authors： Zhang R,Levine BD

更新日期：2007-04-01 00:00:00

abstract：:Background and Purpose- Aneurysmal subarachnoid hemorrhage (aSAH) has a high healthcare cost burden. Methods- We performed a cross-sectional analysis of the costs of clipping and coiling of aSAH using the National Inpatient Sample and Vizient databases. We conducted multiple regression analyses to estimate national co...

journal_title：Stroke

authors： Yoon S,Yoon JC,Winkler E,Liu C,Lawton MT

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND AND PURPOSE:To compare the utility of contrast-enhanced MR Angiography (CE-MRA) with digital subtraction angiography (DSA) after endovascular treatment of intracranial aneurysms with Guglielmi detachable coils. METHODS:From April 1999 to August 2002, 106 patients with 107 aneurysms treated by endovascular c...

journal_title：Stroke

authors： Gauvrit JY,Leclerc X,Caron S,Taschner CA,Lejeune JP,Pruvo JP

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Diffusion-weighted imaging (DWI) is the most sensitive MR sequence in acute arterial ischemic stroke but has not yet been evaluated in venous cerebral ischemia. We describe a patient with DWI performed at the acute phase of a venous ischemic stroke. CASE DESCRIPTION:A rapid cerebral MRI including DWI and fa...

journal_title：Stroke

authors： Corvol JC,Oppenheim C,Manaï R,Logak M,Dormont D,Samson Y,Marsault C,Rancurel G

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild hypothermia has been shown to ameliorate neuronal damage due to cerebral ischemia. In our study, the influence of mild-to-moderate hypothermia was examined in a rabbit model of focal cerebral ischemia. METHODS:After 4 hours of permanent ischemia induced by occlusion of the anterior and midd...

journal_title：Stroke

authors： Lo EH,Steinberg GK

更新日期：1992-06-01 00:00:00

abstract：:Hyperventilation to extremely low arterial carbon dioxide tension (PaCO2) has been used in the management of persistent pulmonary hypertension in newborn infants. With progressive hypocarbia, cerebral vasoconstriction occurs, raising the concern that extreme hypocarbia may result in cerebral oxygen deprivation. Theref...

journal_title：Stroke

authors： Rosenberg AA

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral ischemia (DCI) is the most important cause for a poor clinical outcome after a subarachnoid hemorrhage. The aim of this study was to assess whether goal-directed hemodynamic therapy (GDHT), as compared to standard clinical care, reduces the rate of DCI after subarachnoid hemorrha...

journal_title：Stroke

authors： Anetsberger A,Gempt J,Blobner M,Ringel F,Bogdanski R,Heim M,Schneider G,Meyer B,Schmid S,Ryang YM,Wostrack M,Schneider J,Martin J,Ehrhardt M,Jungwirth B

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A precise definition of genetic factors responsible for common forms of stroke is still lacking. The purpose of the present study was to investigate the contributory role of the genes encoding atrial natriuretic peptide (ANP) and type A natriuretic peptide receptor (NPRA) in humans' susceptibilit...

journal_title：Stroke

authors： Rubattu S,Stanzione R,Di Angelantonio E,Zanda B,Evangelista A,Tarasi D,Gigante B,Pirisi A,Brunetti E,Volpe M

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:To judge the efficacy of new, putative stroke therapies, we need a method to measure neurological deficit accurately in groups of patients before and after treatment. No single measurement technique has yet proven to be universally acceptable, but one approach is the use of rating instruments that summarize ...

journal_title：Stroke

authors： Lyden PD,Lau GT

更新日期：1991-11-01 00:00:00

abstract：:We mapped average age-adjusted stroke mortality rates for white men and white women aged 35-74 years for state economic areas (counties or groups of counties) in the continental United States for three 7-year periods between 1962 and 1982. Despite the decline of national stroke mortality rates, rates in some areas fai...

journal_title：Stroke

authors： Wing S,Casper M,Davis WB,Pellom A,Riggan W,Tyroler HA

更新日期：1988-12-01 00:00:00

abstract：:Background and Purpose- The purpose of this study was to conduct a meta-analysis of CVOTs (cardiovascular outcome trials) to evaluate the effect of glucagon-like peptide-1 receptor agonists therapy in reducing the risk of stroke in patients with type 2 diabetes mellitus. Methods- PubMed and other electronic sources we...

journal_title：Stroke

authors： Bellastella G,Maiorino MI,Longo M,Scappaticcio L,Chiodini P,Esposito K,Giugliano D

更新日期：2020-02-01 00:00:00

abstract：:Unilateral stimulation of the cervical sympathetic in dogs had no effect on cerebral blood flow (CBF) measured by the venous outflow technique. Since this technique measured CBF from both cerebral hemispheres, small changes induced by unilateral stimulation could have been masked by a large constant CBF measured from ...

journal_title：Stroke

authors： Barber BJ,Martin JS,Rapela CE

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pediatric stroke, birth to 18 years, is a significant cause of long-term disability in the United States; however, there is currently little experimental data on the pathophysiology of childhood stroke owing to lack of animal models. We developed a novel mouse model of experimental childhood-onse...

journal_title：Stroke

authors： Herson PS,Bombardier CG,Parker SM,Shimizu T,Klawitter J,Klawitter J,Quillinan N,Exo JL,Goldenberg NA,Traystman RJ

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Familial aggregation of intracranial aneurysms (IAs) indicates a genetic role in the pathogenesis of this disease. Despite a number of reported susceptibility loci, no disease-causing gene variants have been identified. In this study, we used a parametric genomewide linkage approach to search for...

journal_title：Stroke

authors： Santiago-Sim T,Depalma SR,Ju KL,McDonough B,Seidman CE,Seidman JG,Kim DH

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Victims of air embolism often recover rapidly on hyperbaric treatment then deteriorate again, even if hyperbaric treatment is continued. In previous animal experiments, lidocaine has been shown to improve recovery of somatosensory evoked response amplitude after air embolism. However, animals in ...

journal_title：Stroke

authors： Dutka AJ,Mink R,McDermott J,Clark JB,Hallenbeck JM

更新日期：1992-10-01 00:00:00