Diffusion-weighted magnetic resonance imaging in a case of cerebral venous thrombosis.

Abstract:

BACKGROUND:Diffusion-weighted imaging (DWI) is the most sensitive MR sequence in acute arterial ischemic stroke but has not yet been evaluated in venous cerebral ischemia. We describe a patient with DWI performed at the acute phase of a venous ischemic stroke. CASE DESCRIPTION:A rapid cerebral MRI including DWI and fast fluid-attenuated inversion recovery (FLAIR) sequences was performed at the acute phase of a venous stroke confirmed by conventional angiography. DWI showed a slight decrease in apparent diffusion coefficient values 3 hours after onset (0.53+/-0.07x10(-3) mm2/s) and was normal 48 hours later (0.064+/-0.15x10(-3) mm2/s). Fast FLAIR sequences showed large left frontoparietal hyperintensities. The lack of a clear decrease in apparent diffusion coefficient values associated with marked FLAIR abnormalities may suggest prominent or early associated vasogenic edema. Physiopathological differences between arterial and venous ischemia may explain the different type of DWI FLAIR abnormalities during the acute phase as well as the better recovery of neurological deficit in venous stroke than in arterial ischemic stroke. CONCLUSIONS:In the context of an acute stroke, the contrast between marked FLAIR and subtle DWI abnormalities on MRI may reflect the venous mechanism of cerebral ischemia.

journal_name

Stroke

journal_title

Stroke

authors

Corvol JC,Oppenheim C,Manaï R,Logak M,Dormont D,Samson Y,Marsault C,Rancurel G

doi

10.1161/01.str.29.12.2649

subject

Has Abstract

pub_date

1998-12-01 00:00:00

pages

2649-52

issue

12

eissn

0039-2499

issn

1524-4628

journal_volume

29

pub_type

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