There's no place like home : an evaluation of early supported discharge for stroke.

abstract：BACKGROUND AND PURPOSE:Thrombin is activated in the cerebrospinal fluid (CSF) after a subarachnoid hemorrhage (SAH). However, the relationship between thrombin and cerebral vasospasm has not yet been fully established. The aim of this study was to investigate the possibility of thrombin as a causative factor for cerebr...

journal_title：Stroke

authors： Tsurutani H,Ohkuma H,Suzuki S

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have previously reported that extracellular ATP activates P(2u) receptors and increases intracellular free Ca(2+) ([Ca(2+)](i)) by G protein/phospholipase C/inositol 1,4,5-triphosphate pathways in cerebral artery smooth muscle cells. However, the possible contribution of other signaling pathwa...

journal_title：Stroke

authors： Aoki K,Zubkov AY,Parent AD,Zhang JH

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of single-nucleotide polymorphisms (SNPs) associated with increased risk of new intracranial hemorrhage (ICH) after brain arteriovenous malformation (BAVM) diagnosis would facilitate risk stratification and identify potential targets for therapeutic intervention. METHODS:Patients ...

journal_title：Stroke

authors： Achrol AS,Pawlikowska L,McCulloch CE,Poon KY,Ha C,Zaroff JG,Johnston SC,Lee C,Lawton MT,Sidney S,Marchuk DA,Kwok PY,Young WL,UCSF BAVM Study Project.

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate the mechanisms for oxidative injury caused by subarachnoid hemolysate, a pro-oxidant. METHODS:Injection of 50 microL of subarachnoid hemolysate or saline was performed in CD1 mice (n=75), mutant mice deficient in Mn-superoxide dismutase (Sod2+/-; n=23), and their wild-ty...

journal_title：Stroke

authors： Matz PG,Fujimura M,Lewen A,Morita-Fujimura Y,Chan PH

更新日期：2001-02-01 00:00:00

abstract：:We report two patients with mixed transcortical aphasia following left frontal lobe infarctions. Although there was no evidence of anatomic isolation of the speech area on computed tomograms or magnetic resonance imaging scans, single-photon emission computed tomography in one case demonstrated diminished blood flow o...

journal_title：Stroke

authors： Rapcsak SZ,Krupp LB,Rubens AB,Reim J

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is the leading cause of adult disability worldwide. Currently, there is no effective treatment for stroke survivors. Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are the growth factors regulating hematopoiesis. We have previously observed that SCF and G-CSF have...

journal_title：Stroke

authors： Zhao LR,Berra HH,Duan WM,Singhal S,Mehta J,Apkarian AV,Kessler JA

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to determine the effects of aging on regional cerebral blood flow and ischemic brain damage in transient cerebral ischemia in rats. METHODS:Five adult (5-6 months) and five aged (18-22 months) female spontaneously hypertensive rats were subjected to 20 minutes of bilateral carotid occl...

journal_title：Stroke

authors： Yao H,Sadoshima S,Ooboshi H,Sato Y,Uchimura H,Fujishima M

更新日期：1991-11-01 00:00:00

abstract：:Serum dopamine-beta-hydroxylase (DBH) activity was measured in 34 patients with acute cerebrovascular disease. The serum level of DBH activity showed its highest value soon after the onset of stroke and then gradually decreased over the next few days. After reaching its lowest level, the DBH activity again showed a sl...

journal_title：Stroke

authors： Kanda T,Gotoh F,Yamamoto M,Sakai F,Takeoka T,Takagi Y

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies reported that Tat-NR2B9c, a peptide disrupting the N-methyl-d-aspartate receptor-postsynaptic density protein-95 interaction, reduced ischemic damage in the acute phase after stroke. However, its effect in the subacute phase is unknown. The aim of this study is to determine wheth...

journal_title：Stroke

authors： Zhou HH,Tang Y,Zhang XY,Luo CX,Gao LY,Wu HY,Chang L,Zhu DY

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Toll-like receptors (TLRs) and the scavenger receptor CD36 are key molecular sensors for the innate immune response to invading pathogens. However, these receptors may also recognize endogenous "danger signals" generated during brain injury, such as cerebral ischemia, and trigger a maladaptive in...

journal_title：Stroke

authors： Abe T,Shimamura M,Jackman K,Kurinami H,Anrather J,Zhou P,Iadecola C

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke risk increases with age in patients who have nonvalvular atrial fibrillation. It is uncertain whether the efficacy of stroke prevention therapies in atrial fibrillation changes as patients age. The objective of this study was to determine the effect of age on the relative efficacy of oral ...

journal_title：Stroke

authors： van Walraven C,Hart RG,Connolly S,Austin PC,Mant J,Hobbs FD,Koudstaal PJ,Petersen P,Perez-Gomez F,Knottnerus JA,Boode B,Ezekowitz MD,Singer DE

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Incidental magnetic resonance diffusion-weighted imaging (DWI)-positive lesions, considered to represent small acute infarcts, have been detected in patients with cerebral small vessel diseases or cognitive impairment, but the prevalence in the community population is unknown. METHODS:DWI sequen...

journal_title：Stroke

authors： Batool S,O'Donnell M,Sharma M,Islam S,Dagenais GR,Poirier P,Lear SA,Wielgosz A,Teo K,Stotts G,McCreary CR,Frayne R,DeJesus J,Rangarajan S,Yusuf S,Smith EE,PURE Study Investigators.

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of acute ischemic stroke (AIS) cause is crucial for guidance of secondary prevention. Previous studies have yielded inconsistent results regarding possible correlations between AIS cause and thrombus composition, as assessed by semiquantitative histological analysis. Here, we perfo...

journal_title：Stroke

authors： Di Meglio L,Desilles JP,Solonomenjanahary M,Labreuche J,Ollivier V,Dupont S,Deschildre C,Maacha MB,Consoli A,Lapergue B,Piotin M,Blanc R,Ho-Tin-Noe B,Mazighi M,compoCLOT study group†.

更新日期：2020-09-01 00:00:00

abstract：:Life table analysis is a powerful statistical tool that has become the preferred technique for studying both the natural history of and the effect of treatment on disease outcome. We have found only one report using life table analysis to study rehabilitation outcome after stroke. We assessed the recovery of both inde...

journal_title：Stroke

authors： Reding MJ,Potes E

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The use of thrombolysis in acute minor ischemic stroke (MIS) remains controversial. We sought to determine the safety and efficacy of intravenous tissue-type plasminogen activator (IV-tPA) in acute MIS patients with demonstrable penumbra on computed tomographic perfusion study. METHODS:Consecuti...

journal_title：Stroke

authors： Ng FC,Coote S,Frost T,Bladin C,Choi PM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In 2006, the American Heart Association recommended that carotid revascularization generally occurs within 2 weeks of stroke based on data from 2 trials of carotid endarterectomy (CEA). We aimed to determine whether the time between stroke and CEA or carotid artery stenting (CAS) has decreased an...

journal_title：Stroke

authors： Reznik M,Kamel H,Gialdini G,Pandya A,Navi BB,Gupta A

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prevalence of cerebral microbleeds (CMB) in white and Asian populations range from 4% to 15%. However, there is no information from indigenous Latin American people. We aimed to assess prevalence and cerebrovascular correlates of CMB in stroke-free older adults living in rural Ecuador. METHODS:O...

journal_title：Stroke

authors： Del Brutto VJ,Zambrano M,Mera RM,Del Brutto OH

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with unilateral significant carotid artery stenosis present with a variable intracranial hemodynamic status. In the majority of patients, hemodynamics are normal because of sufficient collateral flow. One subgroup shows poor ipsilateral hemodynamics because of a severely reduced blood su...

journal_title：Stroke

authors： Hartl WH,Janssen I,Fürst H

更新日期：1994-10-01 00:00:00

abstract：:Background and Purpose- Carotid web (CW) is a rare form of focal fibromuscular dysplasia defined as an abnormal shelf-like projection of intimal fibrous tissue into the carotid bulb. It is theorized that CW leads to ischemic stroke secondary to blood flow stasis and subsequent embolization. The natural history and opt...

journal_title：Stroke

authors： Zhang AJ,Dhruv P,Choi P,Bakker C,Koffel J,Anderson D,Kim J,Jagadeesan B,Menon BK,Streib C

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Apolipoprotein E polymorphism may influence the early development of coronary artery disease. We investigated the putative role of apolipoprotein E phenotypes in cerebral infarction. METHODS:The apolipoprotein E phenotypes of 69 patients (mean +/- SD age, 72 +/- 11 years) who had suffered comple...

journal_title：Stroke

authors： Couderc R,Mahieux F,Bailleul S,Fenelon G,Mary R,Fermanian J

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aspirin resistance may be relatively common and associated with adverse outcome. Meta-analysis has clearly shown that 75 mg plain aspirin is the lowest effective dose; however, it is not known whether the recent increased use of enteric-coated aspirin could account for aspirin resistance. This st...

journal_title：Stroke

authors： Cox D,Maree AO,Dooley M,Conroy R,Byrne MF,Fitzgerald DJ

更新日期：2006-08-01 00:00:00

abstract：:With the use of a new ultrasonic volume flow meter (VFM), over 8000 measurements of common carotid blood flow were made in 120 normal control subjects and 550 patients with various neurological disease. The accuracy of the flow meter in measuring blood flow on an experimental model ranged from 93 to 97%. In normal sub...

journal_title：Stroke

authors： Uematsu S,Yang A,Preziosi TJ,Kouba R,Toung TJ

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of flow diverter (FD) on hemodynamic changes observed in aneurysms is inevitably affected by the actual structural configuration of deployed FD. We studied the resultant hemodynamic changes after implantation of FDs using computational fluid dynamic simulations based on micro-computed ...

journal_title：Stroke

authors： Huang Q,Xu J,Cheng J,Wang S,Wang K,Liu JM

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although insulin resistance and hyperinsulinemia play a crucial role in the pathogenesis of atherosclerosis, little is known about their roles in ischemic stroke. The purpose of this study was to clarify whether insulin resistance and hyperinsulinemia are causative factors in the pathogenesis of ...

journal_title：Stroke

authors： Shinozaki K,Naritomi H,Shimizu T,Suzuki M,Ikebuchi M,Sawada T,Harano Y

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional walk tests such as the 6- and 12-Minute Walk Test (ie, 6MWT and 12MWT, respectively) are submaximal measures used to determine functional capacity in individuals with compromised ability. The purpose of this study was to determine the relationship between these walk tests and measures ...

journal_title：Stroke

authors： Eng JJ,Chu KS,Dawson AS,Kim CM,Hepburn KE

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulating evidence indicates that inflammatory responses cause secondary injury after intracerebral hemorrhage (ICH). We recently demonstrated the involvement of toll-like receptor 4 (TLR4) signaling in these processes. The purpose of the current study was to investigate the protective effect ...

journal_title：Stroke

authors： Wang YC,Wang PF,Fang H,Chen J,Xiong XY,Yang QW

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Apraxia of speech (AOS) is a motor speech disorder, which is clinically characterized by the combination of phonemic segmental changes and articulatory distortions. AOS has been believed to arise from impairment in motor speech planning/programming and differentiated from both aphasia and dysarth...

journal_title：Stroke

authors： Itabashi R,Nishio Y,Kataoka Y,Yazawa Y,Furui E,Matsuda M,Mori E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vertebrobasilar territory ischemia (VBI) leads to disabling neurological symptoms and poses a risk for stroke by an embolic or flow-related mechanism. We present our clinical experience in the endovascular treatment of patients with symptomatic VBI from severe atherosclerosis or dissection of the...

journal_title：Stroke

authors： Malek AM,Higashida RT,Phatouros CC,Lempert TE,Meyers PM,Gress DR,Dowd CF,Halbach VV

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence indicates that center volume of cases affects outcomes for both carotid endarterectomy and stenting. We evaluated the effect of enrollment volume by site on complication rates in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). METHODS:The primary composite en...

journal_title：Stroke

authors： Gonzales NR,Demaerschalk BM,Voeks JH,Tom M,Howard G,Sheffet AJ,Garcia L,Clair DG,Barr J,Orlow S,Brott TG,CREST Investigators.

更新日期：2014-11-01 00:00:00

abstract：:Exposure of Mongolian gerbils to a 100% oxygen atmosphere after 15 minutes of global brain ischemia resulted in a marked increase in the production of pentane, an in vivo product of lipid peroxidation. Much less pentane production occurred in animals subjected to global brain ischemia then exposed to an air atmosphere...

journal_title：Stroke

authors： Mickel HS,Vaishnav YN,Kempski O,von Lubitz D,Weiss JF,Feuerstein G

更新日期：1987-03-01 00:00:00