Abstract:
BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) monitoring of mean blood flow velocity (mV) during head-upright tilt can allow testing of cerebral autoregulation. Nonetheless, head-upright tilt can induce changes in the ventilation-perfusion relationship and/or respiratory activity that might influence TCD data. METHODS:Forty-eight healthy volunteers underwent monitoring of mV and end-tidal CO2 in the horizontal position and during head-upright tilt. RESULTS:Both mV and end-tidal CO2 significantly decreased in orthostasis (P < .01). Linear regression analysis showed a significant linkage between end-tidal CO2 and mV changes (r = .83, P < .01). CONCLUSIONS:Changes in ventilation-perfusion ratio and in the respiratory pattern induced by head-upright tilt can significantly influence TCD data by determining a PCO2 decrease.
journal_name
Strokejournal_title
Strokeauthors
Cencetti S,Bandinelli G,Lagi Adoi
10.1161/01.str.28.6.1195subject
Has Abstractpub_date
1997-06-01 00:00:00pages
1195-7issue
6eissn
0039-2499issn
1524-4628journal_volume
28pub_type
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