Effect of PCO2 changes induced by head-upright tilt on transcranial Doppler recordings.

Abstract:

BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) monitoring of mean blood flow velocity (mV) during head-upright tilt can allow testing of cerebral autoregulation. Nonetheless, head-upright tilt can induce changes in the ventilation-perfusion relationship and/or respiratory activity that might influence TCD data. METHODS:Forty-eight healthy volunteers underwent monitoring of mV and end-tidal CO2 in the horizontal position and during head-upright tilt. RESULTS:Both mV and end-tidal CO2 significantly decreased in orthostasis (P < .01). Linear regression analysis showed a significant linkage between end-tidal CO2 and mV changes (r = .83, P < .01). CONCLUSIONS:Changes in ventilation-perfusion ratio and in the respiratory pattern induced by head-upright tilt can significantly influence TCD data by determining a PCO2 decrease.

journal_name

Stroke

journal_title

Stroke

authors

Cencetti S,Bandinelli G,Lagi A

doi

10.1161/01.str.28.6.1195

subject

Has Abstract

pub_date

1997-06-01 00:00:00

pages

1195-7

issue

6

eissn

0039-2499

issn

1524-4628

journal_volume

28

pub_type

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