Effects of isovolemic hemodilution on hemodynamics, cerebral perfusion, and cerebral vascular reactivity.

abstract：:Both platelet activating factor and eicosanoids participate in the cerebrovascular response to ischemia. Eicosanoids also modulate cerebrovascular tone under normal physiologic circumstances, but a similar role for platelet activating factor has not been investigated. Therefore, using 16 rats, we studied the effects o...

journal_title：Stroke

authors： Kochanek PM,Melick JA,Schoettle RJ,Magargee MJ,Evans RW,Nemoto EM

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study determines associations between early blood pressure (BP) variability and stroke outcomes after intravenous thrombolysis. METHODS:In 527 stroke patients receiving intravenous alteplase (0.6 mg/kg), BP was measured 8 times within the first 25 hours. BP variability was determined...

journal_title：Stroke

authors： Endo K,Kario K,Koga M,Nakagawara J,Shiokawa Y,Yamagami H,Furui E,Kimura K,Hasegawa Y,Okada Y,Okuda S,Namekawa M,Miyagi T,Osaki M,Minematsu K,Toyoda K

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We investigated changes in locomotor activity, passive avoidance task performance, and hippocampal CA1 neurons induced by cerebral ischemia in Mongolian gerbils to examine the relation between these behavioral changes and CA1 neuronal damage. METHODS:Spontaneous locomotor activity was measured u...

journal_title：Stroke

authors： Karasawa Y,Araki H,Otomo S

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of the present study was to investigate the effects of normobaric oxygen (NBO) therapy on T2*-weighted images of intracranial hemorrhages (ICHs). METHODS:Two common models of ICH were performed in mice, and longitudinal T2*-weighted images of the hematomas were acquired under normoxia or...

journal_title：Stroke

authors： Gaberel T,Gakuba C,Hebert M,Montagne A,Agin V,Rubio M,Emery E,Vivien D,Gauberti M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The goal of this study was to determine the alterations in contractile and dilatory responses and ultrastructure of the feline middle cerebral artery after hemorrhagic hypotension. METHODS:In the sodium pentobarbital anesthetized cats, a steady 50 mm Hg level of hypotension was reached by bleedi...

journal_title：Stroke

authors： Kovách AG,Szabó C,Faragó M,Lohinai Z,Fehér E

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral small vessel disease is the most common cause of vascular dementia. Interest in using MRI parameters as surrogate markers of disease to assess therapies is increasing. In patients with symptomatic sporadic small vessel disease, we determined which MRI parameters best correlated with cogn...

journal_title：Stroke

authors： Nitkunan A,Barrick TR,Charlton RA,Clark CA,Markus HS

更新日期：2008-07-01 00:00:00

abstract：:A 34-year-old, single Japanese woman with active Takayasu's disease presented with stenosed bilateral common carotid arteries, subtotal occlusion of the left subclavian artery, and complete occlusion of the ipsilateral proximal vertebral artery, as demonstrated by angiography. A right subclavian-left vertebral bypass ...

journal_title：Stroke

authors： Ishikawa K,Yonekawa Y

更新日期：1987-05-01 00:00:00

abstract：:The timing of aneurysm surgery is one of the major controversies in the management of subarachnoid hemorrhage. The Cooperative Aneurysm Study is conducting an international epidemiological study to determine mortality and morbidity related to timing of surgery. From January, 1981 to July, 1983 over 3,500 patients have...

journal_title：Stroke

authors： Kassell NF,Torner JC

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Research has identified a number of factors associated with poststroke recovery, but the prediction of long-term functional outcome remains an uncertain endeavor. In previous work, extinction to tactile, double-simultaneous stimulation has been shown to have short-term predictive utility. The pre...

journal_title：Stroke

authors： Rose L,Bakal DA,Fung TS,Farn P,Weaver LE

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To date, few studies have examined associations between the wide range of flavonoid subclasses and risk of ischemic, hemorrhagic, and total stroke. METHODS:We conducted a prospective study among 69 622 women from the Nurses' Health Study. Total flavonoid and subclass intakes were calculated from...

journal_title：Stroke

authors： Cassidy A,Rimm EB,O'Reilly EJ,Logroscino G,Kay C,Chiuve SE,Rexrode KM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolysis for acute ischemic stroke in patients aged > 80 years is not approved in some countries due to limited trial data in the very elderly. We compared outcomes between thrombolysed and nonthrombolysed (control) patients from neuroprotection trials to assess any influence of age on respon...

journal_title：Stroke

authors： Mishra NK,Diener HC,Lyden PD,Bluhmki E,Lees KR,VISTA Collaborators.

更新日期：2010-12-01 00:00:00

abstract：:To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

journal_title：Stroke

authors： Lyden PD,Zivin JA,Kochhar A,Mazzarella V

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Changes in adrenoceptors in the cerebral cortex and hippocampus of Mongolian gerbils after brain ischemia were investigated. METHODS:Twenty-four hours after unilateral occlusion of the common carotid artery, alpha 1-, alpha 2-, and beta-receptors of the membrane fraction of the cerebral cortex o...

journal_title：Stroke

authors： Mizuki T,Kobayashi H,Ueno S,Nakashima Y,Kuroiwa A,Izumi F

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is little data regarding the cost of pediatric stroke care or the elements that contribute to these costs. We examined costs for poststroke care during the first year after diagnosis and compared these costs with the volume of the cerebral infarct and the level of neurological and functiona...

journal_title：Stroke

authors： Lo W,Zamel K,Ponnappa K,Allen A,Chisolm D,Tang M,Kerlin B,Yeates KO

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The association among socioeconomic status, quality of care, and clinical outcome after stroke remains poorly understood. In a Danish nationwide follow-up study, we examined whether socioeconomic-related differences in acute stroke care occur and, if so, whether they explain socioeconomic differe...

journal_title：Stroke

authors： Langagergaard V,Palnum KH,Mehnert F,Ingeman A,Krogh BR,Bartels P,Johnsen SP

更新日期：2011-10-01 00:00:00

abstract：:Background and Purpose- Recanalization with tPA (tissue-type plasminogen activator) is the only pharmacological therapy available for patients with ischemic stroke. However, the percentage of patients who may receive this therapy is limited by the risk of hemorrhagic transformation (HT)-the main complication of ischem...

journal_title：Stroke

authors： García-Yébenes I,García-Culebras A,Peña-Martínez C,Fernández-López D,Díaz-Guzmán J,Negredo P,Avendaño C,Castellanos M,Gasull T,Dávalos A,Moro MA,Lizasoain I

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:CADASIL is a newly recognized cause of subcortical ischemic strokes that progressively leads to dementia associated with pseudobulbar palsy and severe motor disability. This deleterious progression and the severity of clinical presentation are widely variable among affected subjects. The exact ro...

journal_title：Stroke

authors： Chabriat H,Pappata S,Poupon C,Clark CA,Vahedi K,Poupon F,Mangin JF,Pachot-Clouard M,Jobert A,Le Bihan D,Bousser MG

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to characterize the spatial and temporal evolution of human cerebral infarction. Using a novel method of quantitatively mapping the distribution of hypoxic viable tissue identified by 18F-fluoromisonidazole (18F-FMISO) PET relative to the final infarct, we determined its evolution and s...

journal_title：Stroke

authors： Markus R,Reutens DC,Kazui S,Read S,Wright P,Chambers BR,Sachinidis JI,Tochon-Danguy HJ,Donnan GA

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In the Asymptomatic Carotid Surgery Trial-1 (ACST-1), 3120 patients with tight asymptomatic carotid stenosis were randomly assigned to medical treatment alone or to carotid endarterectomy and appropriate medication. Successful carotid endarterectomy significantly reduced 10-year stroke risk in yo...

journal_title：Stroke

authors： den Hartog AG,Halliday AW,Hayter E,Pan H,Kong X,Moll FL,de Borst GJ,Asymptomatic Carotid Surgery Trial Collaborators.

更新日期：2013-06-01 00:00:00

abstract：:Cystatin C, a protein inhibitor of lysosomal cysteine proteinases, was demonstrated by immunohistochemical techniques to be present in the birefringent amyloid deposits of the small arteries in the cerebrum, cerebellum, and leptomeninges of 10 Icelandic individuals with hereditary cerebral hemorrhage with amyloidosis....

journal_title：Stroke

authors： Löfberg H,Grubb AO,Nilsson EK,Jensson O,Gudmundsson G,Blöndal H,Arnason A,Thorsteinsson L

更新日期：1987-03-01 00:00:00

abstract：:To compare the diagnostic yields of transesophageal and transthoracic echocardiography in the detection of potential cardiac sources of embolism, 63 patients (mean +/- SD age 63 +/- 15 [range 18-87] years) with transient ischemic attacks or stroke underwent both procedures. Transthoracic echocardiography revealed a po...

journal_title：Stroke

authors： Cujec B,Polasek P,Voll C,Shuaib A

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulation of endogenous guanidino-substituted analogues of L-arginine in chronic renal failure might contribute to some of the vascular and neurological disorders of this pathology. We tested the hypothesis that in human cerebral arteries, some guanidino compounds may increase vascular tone, t...

journal_title：Stroke

authors： Segarra G,Medina P,Ballester RM,Lluch P,Aldasoro M,Vila JM,Lluch S,Pelligrino DA

更新日期：1999-10-01 00:00:00

abstract：:Patients with chronic aphasia were assigned randomly to a group to receive either conventional aphasia therapy or constraint-induced (CI) aphasia therapy, a new therapeutic technique requiring intense practice over a relatively short period of consecutive days. CI aphasia therapy is realized in a communicative therape...

journal_title：Stroke

authors： Pulvermüller F,Neininger B,Elbert T,Mohr B,Rockstroh B,Koebbel P,Taub E

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Physiologically, it appears plausible for physical activity to decrease stroke risk; however, epidemiological studies have produced mixed findings. Furthermore, few studies have examined specific kinds and intensities of activities. The purpose of this study was to examine the association between...

journal_title：Stroke

authors： Lee IM,Paffenbarger RS Jr

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In intracerebral hemorrhage (ICH), preexisting cognitive impairment has been identified as a risk factor for increased mortality and morbidity. However, previous studies examined predominantly White populations; therefore, the prevalence and effect of preICH cognitive impairment has not been stud...

journal_title：Stroke

authors： Sawyer RP,Yim E,Coleman E,Demel SL,Sekar P,Woo D

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animals, drugs that increase brain amine concentrations influence the rate and degree of recovery from cortical lesions. It is therefore conceivable that antidepressants may influence outcome after ischemic brain injury in humans. We evaluated the effects of the norepinephrine reuptake blocker...

journal_title：Stroke

authors： Dam M,Tonin P,De Boni A,Pizzolato G,Casson S,Ermani M,Freo U,Piron L,Battistin L

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hypothermia reduces neuronal damage in animal stroke models. Whether hypothermia is neuroprotective in patients with acute stroke remains to be clarified. In this case-control study, we evaluated the feasibility and safety of inducing modest hypothermia by a surface cooling method in awake patien...

journal_title：Stroke

authors： Kammersgaard LP,Rasmussen BH,Jørgensen HS,Reith J,Weber U,Olsen TS

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Existing methods for the quantitative measurement of the changing cerebral blood flow (CBF) during reperfusion suffer from poor spatial or temporal resolution. The aim of this study was to implement a recently developed MRI technique for quantitative perfusion imaging in a gerbil model of reperfu...

journal_title：Stroke

authors： Pell GS,Lythgoe MF,Thomas DL,Calamante F,King MD,Gadian DG,Ordidge RJ

更新日期：1999-06-01 00:00:00

abstract：:A randomized controlled trial was conducted to examine the effects of interdisciplinary team care on acute hospitalized stroke patients. After obtaining baseline information on 42 stroke victims receiving conventional care in a general hospital, 130 stroke patients were stratified and randomly assigned either to Tradi...

journal_title：Stroke

authors： Wood-Dauphinee S,Shapiro S,Bass E,Fletcher C,Georges P,Hensby V,Mendelsohn B

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains uncertain whether lower dose intravenous tissue-type plasminogen activator (tPA) for stroke is as effective and safe as the standard dose. METHODS:We analyzed data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China). Patients who were treate...

journal_title：Stroke

authors： Liao X,Wang Y,Pan Y,Wang C,Zhao X,Wang DZ,Wang C,Liu L,Wang Y,Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators.

更新日期：2014-08-01 00:00:00