Silent cerebral infarction in a community-based autopsy series in Japan. The Hisayama Study.

abstract：BACKGROUND AND PURPOSE:Vertebrobasilar territory ischemia (VBI) leads to disabling neurological symptoms and poses a risk for stroke by an embolic or flow-related mechanism. We present our clinical experience in the endovascular treatment of patients with symptomatic VBI from severe atherosclerosis or dissection of the...

journal_title：Stroke

authors： Malek AM,Higashida RT,Phatouros CC,Lempert TE,Meyers PM,Gress DR,Dowd CF,Halbach VV

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The antiplatelet agent sarpogrelate is a selective inhibitor of 5-hydroxytryptamine receptors. The purpose of this study was to compare the efficacy and safety of sarpogrelate with those of aspirin in Japanese ischemic stroke patients. METHODS:In total, 1510 patients with recent cerebral infarct...

journal_title：Stroke

authors： Shinohara Y,Nishimaru K,Sawada T,Terashi A,Handa S,Hirai S,Hayashi K,Tohgi H,Fukuuchi Y,Uchiyama S,Yamaguchi T,Kobayashi S,Kondo K,Otomo E,Gotoh F,S-ACCESS Study Group.

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atherosclerosis is a complex subclinical cardiovascular disorder with a substantial genetic component. This study sought to identify genetic loci influencing carotid plaque in 2 independent samples. METHODS:B-mode ultrasound was performed to determine the presence and area of carotid plaque. Var...

journal_title：Stroke

authors： Dong C,Beecham A,Slifer S,Wang L,Blanton SH,Wright CB,Rundek T,Sacco RL

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Peri-infarct depolarizations (PIDs) that occur in ischemic boundary zones of the cerebral cortex of experimental animals have been shown to promote rather than simply to indicate the evolution of the lesion and are especially prominent in the rat. To study the influence of one factor, species, on...

journal_title：Stroke

authors： Strong AJ,Smith SE,Whittington DJ,Meldrum BS,Parsons AA,Krupinski J,Hunter AJ,Patel S,Robertson C

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with arteriovenous malformations are younger individuals who are at risk of a stroke or have experienced one. Our objective was to determine these patients' perceptions of quality of life with a stroke by eliciting utility values. METHODS:Utility values were obtained with the standard g...

journal_title：Stroke

authors： Shin AY,Porter PJ,Wallace MC,Naglie G

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticoagulation is a highly effective secondary prevention in patients with cardioembolic stroke and atrial fibrillation/flutter (AF). However, the condition remains underdiagnosed, because paroxysmal AF may be missed by diagnostic tests in the acute phase. In this study, the sensitivity of AF de...

journal_title：Stroke

authors： Kallmünzer B,Breuer L,Hering C,Raaz-Schrauder D,Kollmar R,Huttner HB,Schwab S,Köhrmann M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The association among socioeconomic status, quality of care, and clinical outcome after stroke remains poorly understood. In a Danish nationwide follow-up study, we examined whether socioeconomic-related differences in acute stroke care occur and, if so, whether they explain socioeconomic differe...

journal_title：Stroke

authors： Langagergaard V,Palnum KH,Mehnert F,Ingeman A,Krogh BR,Bartels P,Johnsen SP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Embolization with coils is increasingly used for the treatment of intracranial aneurysms. To assess the percentage of complications, the percentage of aneurysm occlusion, and the short-term outcome, we performed a systematic review of studies on embolization with controlled detachable or pushable coils. SUM...

journal_title：Stroke

authors： Brilstra EH,Rinkel GJ,van der Graaf Y,van Rooij WJ,Algra A

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the cause of stroke among patients with patent foramen ovale (PFO) may be due to paradoxical cerebral embolism (PCE), this mechanism is often difficult to prove. The aim of our study was to evaluate the association between brain imaging findings suggestive of embolism and PFO among ische...

journal_title：Stroke

authors： Steiner MM,Di Tullio MR,Rundek T,Gan R,Chen X,Liguori C,Brainin M,Homma S,Sacco RL

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of our study was to clarify the pathophysiology of perioperative cerebral complications during carotid endarterectomy in our series. METHODS:By means of transcranial Doppler ultrasonography and stump pressure measurement, we monitored 112 patients who underwent carotid endarterectomy und...

journal_title：Stroke

authors： Finocchi C,Gandolfo C,Carissimi T,Del Sette M,Bertoglio C

更新日期：1997-12-01 00:00:00

abstract：UNLABELLED:The pathophysiology of postischemic encephalopathy is complex, and includes tissue acidosis, edema, hypoperfusion, membrane dysfunction, impaired energy production, and possibly hypermetabolism. We tested the hypothesis that this multifactorial clinical problem must be approached with multifaceted therapy, w...

journal_title：Stroke

authors： Gisvold SE,Safar P,Rao G,Moossy J,Kelsey S,Alexander H

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the modified Rankin Scale (mRS) is the most commonly used primary end point in acute stroke trials, its power is limited when analyzed in dichotomized fashion and its indication of effect size challenging to interpret when analyzed ordinally. Weighting the 7 Rankin levels by utilities ma...

journal_title：Stroke

authors： Chaisinanunkul N,Adeoye O,Lewis RJ,Grotta JC,Broderick J,Jovin TG,Nogueira RG,Elm JJ,Graves T,Berry S,Lees KR,Barreto AD,Saver JL,DAWN Trial and MOST Trial Steering Committees.,Additional contributors from DAWN Trial Steering

更新日期：2015-08-01 00:00:00

abstract：:In the period 1977-1982, the Danish National Patient Register recorded 1000 cases of cerebral thromboembolic attacks among women 15-44 years of age, and 971 cases among men of the same age. Cerebral infarction accounted for 70% of cases and transient ischemic attacks (TIA) for the remaining 30%. By analysing this mate...

journal_title：Stroke

authors： Lidegaard O,Soe M,Andersen MV

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Changes in stroke incidence are likely to occur as a consequence of aging of the population, but evidence for this hypothesis is lacking. METHODS:A prospective community-based registry of first-ever strokes (1994 to 1998) classified according to the International Classification of Diseases, 9th ...

journal_title：Stroke

authors： Carolei A,Marini C,Di Napoli M,Di Gianfilippo G,Santalucia P,Baldassarre M,De Matteis G,di Orio F

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The ability of therapeutic exercise after stroke to improve daily functioning and quality of life (QOL) remains controversial. We examined treatment effects on these outcomes in a randomized controlled trial (RCT) of exercise in subacute stroke survivors. METHODS:This is a secondary analysis of ...

journal_title：Stroke

authors： Studenski S,Duncan PW,Perera S,Reker D,Lai SM,Richards L

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Victims of air embolism often recover rapidly on hyperbaric treatment then deteriorate again, even if hyperbaric treatment is continued. In previous animal experiments, lidocaine has been shown to improve recovery of somatosensory evoked response amplitude after air embolism. However, animals in ...

journal_title：Stroke

authors： Dutka AJ,Mink R,McDermott J,Clark JB,Hallenbeck JM

更新日期：1992-10-01 00:00:00

abstract：:The protective properties of PY 108-068 against ischemic disturbances in the brain were investigated in vitro and in vivo. The calcium antagonistic effects were demonstrated on isolated, calcium-loaded arterial rings of feline cerebral arteries. Determination of brain tissue oxygenation with pO2 microelectrodes showed...

journal_title：Stroke

authors： Wiernsperger N,Gygax P,Hofmann A

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The relationship between the pattern of alcohol intake and the risk of stroke is unclear, in particular the increased risk observed in abstainers and the possible protective effect of light to moderate drinking. For that reason, we examined in a large prospective study the role of alcohol consump...

journal_title：Stroke

authors： Wannamethee SG,Shaper AG

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Shoulder pain is a common complication after stroke that can impede participation in rehabilitation and has been associated with poorer outcomes. Evidence-based treatments for hemiplegic shoulder pain are limited. Suprascapular nerve block (SSNB) is a safe and effective treatment of shoulder pain...

journal_title：Stroke

authors： Adey-Wakeling Z,Crotty M,Shanahan EM

更新日期：2013-11-01 00:00:00

abstract：:To elucidate the connection between blood flow and the localized genesis and development of atherosclerosis and thrombosis at the human carotid artery bifurcation, detailed studies of the flow patterns and distributions of fluid velocity and wall shear rate in this region were carried out using a transparent segment o...

journal_title：Stroke

authors： Motomiya M,Karino T

更新日期：1984-01-01 00:00:00

abstract：:Recent data strongly suggest that repetitive ischemic episodes have an adverse cumulative effect on development of edema and tissue damage. We wanted to assess further whether special risks such as exacerbation of extracellular acidification reflecting progressive exhaustion of the capacity to buffer H+ in the extrace...

journal_title：Stroke

authors： Matsumoto T,Obrenovitch TP,Parkinson NA,Symon L

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral autoregulation may be impaired in the early days after subarachnoid hemorrhage (SAH). The purpose of this study was to examine the relationship between cerebral autoregulation and angiographic vasospasm (aVSP) and radiographic delayed cerebral ischemia (DCI) in patients with SAH. METHOD...

journal_title：Stroke

authors： Otite F,Mink S,Tan CO,Puri A,Zamani AA,Mehregan A,Chou S,Orzell S,Purkayastha S,Du R,Sorond FA

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A previous trial (the Clomethiazole Acute Stroke Study) generated the hypothesis that clomethiazole is effective in patients with a major ischemic stroke (total anterior circulation syndrome), and this was tested in the present study. METHODS:A total of 1198 patients with major ischemic stroke a...

journal_title：Stroke

authors： Lyden P,Shuaib A,Ng K,Levin K,Atkinson RP,Rajput A,Wechsler L,Ashwood T,Claesson L,Odergren T,Salazar-Grueso E,CLASS-I\/H\/T Investigators.

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombin, heme oxygenase, complement, microglia activation, and leukocyte infiltration are all actively upregulated in intracerebral hemorrhage (ICH). Experimental evidence suggests that all these factors are involved in ICH-induced brain injury. This suggests a scenario whereby ICH actively (thr...

journal_title：Stroke

authors： Keep RF,Xi G,Hua Y,Hoff JT

更新日期：2005-07-01 00:00:00

abstract：:The effect of very-low-dose aspirin as an antithrombotic agent was evaluated blindly in 301 patients who had recently undergone carotid endarterectomy. After randomization, 150 patients received aspirin and 151 received placebo. The two groups were comparable with regard to age, sex, blood pressure, previous cerebrova...

journal_title：Stroke

authors： Boysen G,Sørensen PS,Juhler M,Andersen AR,Boas J,Olsen JS,Joensen P

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Uric acid (UA) is a neuroprotective antioxidant that improves the benefits of alteplase in experimental ischemia. However, it is unknown whether endogenous UA also influences the response to thrombolysis in patients with stroke. METHODS:A total of 317 consecutive patients treated with thrombolys...

journal_title：Stroke

authors： Amaro S,Urra X,Gómez-Choco M,Obach V,Cervera A,Vargas M,Torres F,Rios J,Planas AM,Chamorro A

更新日期：2011-01-01 00:00:00

abstract：:Cerebral blood flow and clinical parameters were studied in 30 stroke patients at 15th, 30th, 60th, 90th days after the cerebral insult (Xenon 133 inhalation method). The clinical improvement was not accompanied by a progressive normalization of the CBF at rest. No relationship was found between the clinical data and ...

journal_title：Stroke

authors： Demeurisse G,Verhas M,Capon A,Paternot J

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Flow Diverters (FD) are a new emerging therapy for intracranial aneurysms. Initial reports focused on the treatment of proximally located aneurysms. We report our experience with FDs in the treatment of aneurysms at and beyond the circle of Willis. METHODS:We treated 30 aneurysms at and beyond t...

journal_title：Stroke

authors： Pistocchi S,Blanc R,Bartolini B,Piotin M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis and quantification of microangiopathy in dementia is difficult. The assessment of small-vessel disease requires expensive and sophisticated nuclear medicine techniques. This study was performed to identify microangiopathy related to the integrity of cerebral microcirculation by sono...

journal_title：Stroke

authors： Puls I,Hauck K,Demuth K,Horowski A,Schliesser M,Dörfler P,Scheel P,Toyka KV,Reiners K,Schöning M,Becker G

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neuroprotective effects of electric stimulation have been recently shown in ischemic stroke, but the underlying mechanisms remain poorly understood. METHODS:Adult Wistar rats weighing 200 to 250 g received occlusion of the right middle cerebral artery for 90 minutes. At 1 hour after reperfusion,...

journal_title：Stroke

authors： Baba T,Kameda M,Yasuhara T,Morimoto T,Kondo A,Shingo T,Tajiri N,Wang F,Miyoshi Y,Borlongan CV,Matsumae M,Date I

更新日期：2009-11-01 00:00:00