Abstract:
:In the period 1977-1982, the Danish National Patient Register recorded 1000 cases of cerebral thromboembolic attacks among women 15-44 years of age, and 971 cases among men of the same age. Cerebral infarction accounted for 70% of cases and transient ischemic attacks (TIA) for the remaining 30%. By analysing this material we found an average age-adjusted incidence rate of cerebral thromboembolism of 14.4/100.000 among men and 15.5/100.000 among women. The incidence rates rose rapidly with increasing age. Women aged 15-34 had significantly higher incidence rates of brain infarction and TIA compared to those of men of the same age. This was reversed in the age group 35-44. The magnitude of the ratio between the female and the male mean incidence rates by increasing age corresponded exactly to the age distribution of the use of oral contraceptives in Denmark. The relative risk for developing cerebral thromboembolism among users of oral contraceptives was estimated to be 3.2-6.5. The mortality in male patients with brain infarction was 3.3% and in females 1.7%. The mean duration of stay in hospital was 8.8 days for TIA and about 26 days for cerebral infarction. Sixteen percent of men and 13.6% of women had hypertension during their stay.
journal_name
Strokejournal_title
Strokeauthors
Lidegaard O,Soe M,Andersen MVdoi
10.1161/01.str.17.4.670subject
Has Abstractpub_date
1986-07-01 00:00:00pages
670-5issue
4eissn
0039-2499issn
1524-4628journal_volume
17pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:A right-to-left shunt can be identified by contrast transcranial Doppler ultrasonography (c-TCD) at rest and/or after a Valsalva maneuver (VM) or by arterial blood gas (ABG) measurement. We assessed the influence of controlled strain pressures and durations during VM on the right-to-left passage ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000119384.28376.EB
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Abnormalities of dermal connective tissue have been detected in patients with spontaneous cervical artery dissections (sCAD), suggesting an underlying structural defect of the arterial wall. Alpha1-antitrypsin (A1-AT) is a circulating serine proteinase inhibitor of proteolytic enzymes that helps ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000085085.20390.A3
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Few cohort studies have examined the association of carotid intima-media thickness (IMT) and plaque characteristics with the risk of stroke in apparently healthy persons. We examined the relationship of carotid IMT and the surface, morphology, and calcification of carotid plaques with the inciden...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000147723.52033.9e
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral small vessel disease is the most common cause of vascular dementia. Interest in using MRI parameters as surrogate markers of disease to assess therapies is increasing. In patients with symptomatic sporadic small vessel disease, we determined which MRI parameters best correlated with cogn...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.507475
更新日期:2008-07-01 00:00:00
abstract::Background and Purpose- Perihemorrhagic edema (PHE) is associated with poor outcome after intracerebral hemorrhage (ICH). Infiltration of immune cells is considered a major contributor of PHE. Recent studies suggest that immunomodulation via S1PR (sphingosine-1-phosphate receptor) modulators improve outcome in ICH. Si...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.027134
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The durability of carotid endarterectomy (CEA) in young adults with premature carotid atherosclerosis has not been adequately assessed. This study examined the late recurrence and mortality rates in young adults undergoing CEA. METHODS:We studied 42 young patients (mean age, 45.5 +/- 0.5 years) ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.9.1502
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Dabigatran-etexilate (DE) recently has been approved for stroke prevention in atrial fibrillation. However, lack of effective antagonists represents a major concern in the event of intracerebral hemorrhage (ICH). The aims of the present study were to establish a murine model of ICH associated wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.624650
更新日期:2011-12-01 00:00:00
abstract::Perforating branches of the middle cerebral arteries (MCA) were examined on the forebrain hemispheres of fourteen human brains. It was noticed that their intracerebral segments arose from the MCA main trunk, and its terminal and collateral (cortical) branches. They terminated in certain parts of the basal ganglia and ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.16.6.1022
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Inflammatory and immune mechanisms can precipitate cerebrovascular thrombosis and hemorrhage. Immunologic tolerance can be induced to a specific antigen by intranasal instillation of that antigen. Lymphocytes tolerized in this way provide local immunosuppression on restimulation with the same ant...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.0000029821.82531.8b
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To date, studies on neonatal stroke have mainly focused on cortical stroke. We have focused on perforator strokes, noncortical strokes in the arterial vascular perforator area. We sought to identify risk factors and evaluate clinical presentation and neuroimaging findings for neonatal perforator ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.001064
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Identification of single-nucleotide polymorphisms (SNPs) associated with increased risk of new intracranial hemorrhage (ICH) after brain arteriovenous malformation (BAVM) diagnosis would facilitate risk stratification and identify potential targets for therapeutic intervention. METHODS:Patients ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000195133.98378.4b
更新日期:2006-01-01 00:00:00
abstract::Cerebral autoregulation can be duplicated in vitro using the large middle cerebral arteries from a calf. The limits of autoregulation were between 50 and 150 mm Hg. Excessively high pressures may lead to the appearance of the "sausage- or bead-string" response followed by forced dilation. These results suggest the exi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.12.5.640
更新日期:1981-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We examined whether hemodynamic and metabolic abnormalities in the cerebral white matter, basal ganglia, and thalamus are associated with asymptomatic white matter lesions (WML) depicted on MR images. METHODS:A positron emission tomographic study with H2(15)O, C15O, and 15O2 was performed in eig...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.10.1944
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Few pediatric reports of thrombolysis exist. We sought to determine national rates of thrombolysis among pediatric ischemic stroke patients using a national database. METHODS:Patients between the ages of 1 and 17 years, entered in the Nationwide Inpatient Sample between 2000 and 2003, with Inter...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.106.473983
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:High-dose human albumin (ALB) is robustly neuroprotective in rodent stroke models. A phase I dose-escalation study was conducted to assess the safety of ALB therapy in ischemic stroke. We analyzed the data for preliminary evidence of treatment efficacy. METHODS:Eighty-two subjects with acute isc...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000231389.34701.b5
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Telomerase reverse transcriptase (TERT) is tightly related to the resistance of cells to stress and injury. However, little is known about the roles of TERT in the nervous system. We try to investigate the effects of TERT on the function of astrocytes in developing rat brains subjected to hypoxia...
journal_title:Stroke
pub_type: 杂志文章,收录出版
doi:10.1161/STROKEAHA.111.626325
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Waist circumference has been shown to be a better predictor of cardiovascular risk than body mass index (BMI). Our case-control study aimed to evaluate the contribution of obesity and abdominal fat mass to the risk of stroke and transient ischemic attacks (TIA). METHODS:We recruited 1137 partici...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.523001
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Downregulation of the tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN), is thought to be a novel neuroprotective strategy in ischemic stroke, but the underlying mechanisms remain unclear. In this study, we aimed to validate the use of PTEN regulation of gamma-amino...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.579011
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In acute stroke patients with intracranial vessel occlusion, angiographic demonstration of antegrade contrast opacification distal to the occlusion site (termed the "clot outline sign") has been associated with higher rates of vessel recanalization. We sought to determine whether antegrade flow c...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.112.668889
更新日期:2012-11-01 00:00:00
abstract::There is a strong link between antiphospholipid antibodies and stroke. Retrospective studies indicate that these patients are generally young, often have had prior thrombotic events including stroke, frequently complain of headaches, and often experience amaurosis fugax. Cardiac valvular lesions, particularly involvin...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Motor dysfunction after unilateral deafferentation in primates can be overcome by restraining the unaffected limb. We asked whether a constraint-induced movement (CIM) program could be implemented within 2 weeks after stroke and whether CIM is more effective than traditional upper-extremity (UE) ...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.str.31.12.2984
更新日期:2000-12-01 00:00:00
abstract::We describe a patient with transient ischemic attacks secondary to a giant aneurysm who showed increased activity on platelet scintigrams at the origin of the left vertebral artery. This is assumed to be the first report of a presumed embolizing aneurysm with positive activity of labeled platelets. Platelet scintigrap...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.5.687
更新日期:1989-05-01 00:00:00
abstract::We investigated seasonal variation in the incidence of cerebral stroke among the general population aged greater than or equal to 40 years in November of 1961 in Hisayama, Japan. During the 24-year follow-up period, 311 cases of cerebrovascular diseases occurred. The date or month of onset was determined in 308 cases,...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.9.1262
更新日期:1990-09-01 00:00:00
abstract::To elucidate the role of the internal elastic lamina in the development of cerebral aneurysm, the bifurcation of the anterior cerebral artery and olfactory artery was histologically studied in control and experimental rats treated with unilateral carotid ligation and renal hypertension. Various stages of aneurysm form...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.4.507
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The spontaneously hypertensive stroke-prone rat (SHRSP) is an animal model for a complex form of cerebrovascular pathology. MRI provides an efficient and noninvasive tool for studying the time course of brain damage. The aim of this study was to gain new insights into the pathological phenomena r...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/hs0302.104111
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Computed tomography (CT) is used to study coronary artery plaques, but little is known about its potential to characterize plaque composition. This study assesses the relation between carotid calcium score (CCS) by CT and plaque composition, namely extracellular matrix, inflammatory mediators, an...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.620658
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Coffee and tea consumption could potentially reduce the risk of stroke because these beverages have antioxidant properties, and coffee may improve insulin sensitivity. We examined the associations of coffee and tea consumption with risk of stroke subtypes. METHODS:We used prospective data from t...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.107.504183
更新日期:2008-06-01 00:00:00
abstract::Background and Purpose- The simplified stroke-thrombolytic predictive instrument (s-Stroke-TPI) is useful for predicting the outcomes in thrombolysis-treated patients in Western populations. We aimed to validate its predictive value in Chinese patients. Methods- Data from thrombolysis implementation and monitor of acu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.022269
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Results from large multicenter studies have shown that carotid endarterectomy, performed with low perioperative morbidity and mortality, is beneficial for patients with symptomatic carotid stenosis > or = 70% as calculated according to strict angiographic criteria. To apply these results in clini...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.8.1325
更新日期:1995-08-01 00:00:00
abstract::We produced unilateral photochemical infarcts in the hindlimb sensorimotor neocortex of 186 rats by intravenous injection of the fluorescein derivative rose bengal and focal illumination of the intact skull surface. Infarcted rats showed specific, long-lasting deficits in tactile and proprioceptive placing reactions o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.10.1383
更新日期:1989-10-01 00:00:00