Electrical stimulation of the cerebral cortex exerts antiapoptotic, angiogenic, and anti-inflammatory effects in ischemic stroke rats through phosphoinositide 3-kinase/Akt signaling pathway.

abstract：BACKGROUND AND PURPOSE:Some clinical models, like California ABCD and unified ABCD2 scores, are now available to predict the early risk of stroke after a TIA. Despite the transitivity of symptoms, DWI identified an area of acute brain ischemia in almost half of patients. It would be interesting to know how the presence...

journal_title：Stroke

authors： Purroy F,Begué R,Quílez A,Piñol-Ripoll G,Sanahuja J,Brieva L,Setó E,Gil MI

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral venous thrombosis (CVT) may be a manifestation of underlying autoimmune disease. Antibodies against annexin A2 (anti-A2Ab) coincide with antiphospholipid syndrome, in which antiphospholipid antibodies (aPLA) are associated with thrombosis in any vascular bed. Annexin A2, a profibrinolyti...

journal_title：Stroke

authors： Cesarman-Maus G,Cantú-Brito C,Barinagarrementeria F,Villa R,Reyes E,Sanchez-Guerrero J,Hajjar KA,Latorre EG

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Telestroke has been effective in the management of acute ischemic stroke. This study characterizes and compares stroke specialist (SS) and emergency physician (EP) perceptions of telestroke and identifies barriers preventing increased implementation. METHODS:A survey was developed and distribute...

journal_title：Stroke

authors： Moskowitz A,Chan YF,Bruns J,Levine SR

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multifocal signal loss lesions (MSLLs) on T2*-weighted gradient-echo (GE) MRI are believed to be microbleeds histopathologically. Previous epidemiological studies suggested that low serum cholesterol is associated with the increased risk of intracerebral hemorrhage. We investigated risk factors o...

journal_title：Stroke

authors： Lee SH,Bae HJ,Yoon BW,Kim H,Kim DE,Roh JK

更新日期：2002-12-01 00:00:00

abstract：:The presence of hyperglycemia prior to stroke or cardiac arrest can increase neuronal damage caused by brain ischemia. Acute hyperglycemia shows this effect in animal models of stroke. However, chronic hyperglycemia and chronic hyperglycemia with additional acute elevation of blood glucose are more common premorbid st...

journal_title：Stroke

authors： Duckrow RB,Beard DC,Brennan RW

更新日期：1987-01-01 00:00:00

abstract：:We produced unilateral photochemical infarcts in the hindlimb sensorimotor neocortex of 186 rats by intravenous injection of the fluorescein derivative rose bengal and focal illumination of the intact skull surface. Infarcted rats showed specific, long-lasting deficits in tactile and proprioceptive placing reactions o...

journal_title：Stroke

authors： De Ryck M,Van Reempts J,Borgers M,Wauquier A,Janssen PA

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our aim in this study was to assess the incidence and determining factors of angiographic recurrences after endovascular treatment of aneurysms. METHODS:A retrospective analysis of all patients with selective endosaccular coil occlusion of intracranial aneurysms prospectively collected from 1992...

journal_title：Stroke

authors： Raymond J,Guilbert F,Weill A,Georganos SA,Juravsky L,Lambert A,Lamoureux J,Chagnon M,Roy D

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite its high prevalence in stroke survivors, there is little clinical research on bowel dysfunction in this population. This is the first randomized controlled trial to evaluate treatment of constipation and fecal incontinence in stroke survivors. METHODS:Stroke patients with constipation or...

journal_title：Stroke

authors： Harari D,Norton C,Lockwood L,Swift C

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) caused by ruptured intracranial aneurysm affects approximately 16 000 Americans annually, and almost 40% of affected patients die within 30 days despite the best current therapy. Prevention of SAH is therefore of paramount importance. We present a preliminary analysi...

journal_title：Stroke

authors： Kissela BM,Sauerbeck L,Woo D,Khoury J,Carrozzella J,Pancioli A,Jauch E,Moomaw CJ,Shukla R,Gebel J,Fontaine R,Broderick J

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...

journal_title：Stroke

authors： Brouwers HB,Battey TW,Musial HH,Ciura VA,Falcone GJ,Ayres AM,Vashkevich A,Schwab K,Viswanathan A,Anderson CD,Greenberg SM,Pomerantz SR,Ortiz CJ,Goldstein JN,Gonzalez RG,Rosand J,Romero JM

更新日期：2015-09-01 00:00:00

abstract：:Patients with chronic aphasia were assigned randomly to a group to receive either conventional aphasia therapy or constraint-induced (CI) aphasia therapy, a new therapeutic technique requiring intense practice over a relatively short period of consecutive days. CI aphasia therapy is realized in a communicative therape...

journal_title：Stroke

authors： Pulvermüller F,Neininger B,Elbert T,Mohr B,Rockstroh B,Koebbel P,Taub E

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to identify the most powerful binary measures of the treatment effect of tissue plasminogen activator (tPA) in the National Institute of Neurological Disorders and Stroke (NINDS) rTPA Stroke Trial. METHODS:Using the Classification and Regression Tree (CART) algorithm, we evaluated bina...

journal_title：Stroke

authors： Broderick JP,Lu M,Kothari R,Levine SR,Lyden PD,Haley EC,Brott TG,Grotta J,Tilley BC,Marler JR,Frankel M

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Increasing attention has been paid to associations between cognitive dysfunction and brain microbleeds (MBs). Because all previous studies have investigated patients with neurological disorders, we examined subjects without neurological disorder in order to clarify pathogenic relationships. METH...

journal_title：Stroke

authors： Yakushiji Y,Nishiyama M,Yakushiji S,Hirotsu T,Uchino A,Nakajima J,Eriguchi M,Nanri Y,Hara M,Horikawa E,Kuroda Y

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Antiplatelet therapy is currently one of the methods for preventing transient ischemic attacks and cerebral thrombosis. Because antiplatelet agents are generally administered on a long-term basis, patient compliance is an important factor. The purpose of this study was to determine the compliance...

journal_title：Stroke

authors： Komiya T,Kudo M,Urabe T,Mizuno Y

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microanatomy studies reveal that most penetrating branches of middle cerebral artery (MCA) arise from the dorsal-superior surface of the trunk. Using high-resolution MRI, we sought to explore the plaque distribution of MCA atherosclerosis and its clinical relevance in relation to the orifices of ...

journal_title：Stroke

authors： Xu WH,Li ML,Gao S,Ni J,Zhou LX,Yao M,Peng B,Feng F,Jin ZY,Cui LY

更新日期：2011-10-01 00:00:00

abstract：:Background and Purpose- The impact of a mobile stroke unit (MSU) on access to intraarterial thrombectomy (IAT) is a prespecified BEST-MSU substudy (Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services). On the MSU, IAT decision-making steps, su...

journal_title：Stroke

authors： Czap AL,Grotta JC,Parker SA,Yamal JM,Bowry R,Sheth SA,Rajan SS,Hwang H,Singh N,Bratina P,Bryndziar T,Alexandrov AV,Alexandrov AW,Dusenbury W,Swatzell V,Jones W,Ackerson K,Schimpf B,Wright P,Jagolino-Cole AL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acetazolamide is commonly used with single-photon CT to assess the cerebrovascular reserve in patients with internal carotid artery stenosis or occlusion. In this study we wanted to evaluate the effects of adenosine, a well-known vasodilatatory compound with a short biological half-life, on brain...

journal_title：Stroke

authors： Soricelli A,Postiglione A,Cuocolo A,De Chiara S,Ruocco A,Brunetti A,Salvatore M,Ell PJ

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:While brain tissue lactate increases during cerebral ischemia and is known to be important in the pathogenesis of ischemic brain injury, patterns of extracellular lactate accumulation have been less well characterized, and the influence of brain temperature has not been previously investigated. M...

journal_title：Stroke

authors： Lin B,Busto R,Globus MY,Martinez E,Ginsberg MD

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent evidence suggests that physiological changes in the concentration of endogenous estrogens may influence stroke outcome. The purpose of this study was to determine a menstrual cycle-related profile of blood flow through the carotid arteries and its correlation with estrogen concentration. ...

journal_title：Stroke

authors： Krejza J,Mariak Z,Huba M,Wolczynski S,Lewko J

更新日期：2001-01-01 00:00:00

abstract：:Occlusion of the anterior cerebral artery is a rare condition. A review of CT scans from 413 patients with ischemic infarction confirmed this low relative incidence: only 3% of CT scans evidencing infarction involved the territory of the anterior cerebral artery. Four major mechanisms of anterior cerebral artery occlu...

journal_title：Stroke

authors： Gacs G,Fox AJ,Barnett HJ,Vinuela F

更新日期：1983-11-01 00:00:00

abstract：:Experimental regional cerebral ischemia was produced in the middle cerebral artery (MCA) territory in primates (M. mulatta) by macrosphere embolization. Determinations of percentage tissue dry weight and tissue sodium and potassium concentrations were obtained in samples from the ischemic and non-ischemic hemispheres ...

journal_title：Stroke

authors： Bremer AM,Yamada K,West CR

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Numerous studies indicate that mild hypothermia provides substantial neuroprotection. However, current systems transfer insufficient heat to rapidly vary core temperature. We thus evaluated the safety and efficacy of endovascular cooling and rewarming for the induction and reversal of hypothermia...

journal_title：Stroke

authors： Dae MW,Gao DW,Ursell PC,Stillson CA,Sessler DI

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Motor dysfunction after unilateral deafferentation in primates can be overcome by restraining the unaffected limb. We asked whether a constraint-induced movement (CIM) program could be implemented within 2 weeks after stroke and whether CIM is more effective than traditional upper-extremity (UE) ...

journal_title：Stroke

authors： Dromerick AW,Edwards DF,Hahn M

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence indicates that center volume of cases affects outcomes for both carotid endarterectomy and stenting. We evaluated the effect of enrollment volume by site on complication rates in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). METHODS:The primary composite en...

journal_title：Stroke

authors： Gonzales NR,Demaerschalk BM,Voeks JH,Tom M,Howard G,Sheffet AJ,Garcia L,Clair DG,Barr J,Orlow S,Brott TG,CREST Investigators.

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild stroke (MS) and rapidly improving stroke (RIS) symptoms are common stroke presentations. Our objective is to describe the short-term outcomes in this population. METHODS:A retrospective analysis of patients with ischemic stroke in the Get With The Guidelines-Stroke registry who arrived ≤4.5...

journal_title：Stroke

authors： Romano JG,Smith EE,Liang L,Gardener H,Campo-Bustillo I,Khatri P,Bhatt DL,Fonarow GC,Sacco RL,Schwamm LH

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous work has shown that rates of cerebral microemboli downstream of high-grade internal carotid artery stenosis are higher in recently symptomatic compared with asymptomatic patients. In addition, microembolic rates decline after carotid endarterectomy. We conducted a prospective investigati...

journal_title：Stroke

authors： Sitzer M,Müller W,Siebler M,Hort W,Kniemeyer HW,Jäncke L,Steinmetz H

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clomethiazole is a neuroprotective drug that enhances gamma-aminobutyrate type A (GABA(A)) receptor activity. Its efficacy and safety were tested in the CLomethiazole Acute Stroke Study (CLASS). The protocol allowed a CT scan to be done after randomization but within 7 days of stroke onset to min...

journal_title：Stroke

authors： Wahlgren NG,Díez-Tejedor E,Teitelbaum J,Arboix A,Leys D,Ashwood T,Grossman E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Postischemic cerebral inflammation may contribute to ischemic cell damage. Intercellular adhesion molecule-1 (ICAM-1) is a glycoprotein expressed on endothelial cells that facilitates leukocyte adhesion. We investigated the effect of administration of an anti-ICAM-1 antibody (1A29) on ischemic ce...

journal_title：Stroke

authors： Zhang RL,Chopp M,Jiang N,Tang WX,Prostak J,Manning AM,Anderson DC

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is inconclusive evidence of the effectiveness of psychological interventions for depression after stroke. We report the results from a randomized controlled trial of cognitive behavioral therapy (CBT). METHODS:Stroke patients admitted to hospital were invited to complete mood questionnaire...

journal_title：Stroke

authors： Lincoln NB,Flannaghan T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The underlying mechanisms for reductions in cerebral blood flow (CBF) during orthostasis are not completely understood. This study tested the hypothesis that sympathetic activation causes cerebral vasoconstriction leading to reductions in CBF during lower body negative pressure (LBNP). METHODS:C...

journal_title：Stroke

authors： Zhang R,Levine BD

更新日期：2007-04-01 00:00:00