Safety and efficacy of endovascular cooling and rewarming for induction and reversal of hypothermia in human-sized pigs.

abstract：:In a group of 48 patients with completed stroke, 8 patients had viable collaterally perfused brain tissue which was accessible for rCBF recordings with a two dimensional technique. All 8 had deep subcortical infarcts on CT-scan, and angiographic occlusion of the arteries normally supplying the infarcted territory. The...

journal_title：Stroke

authors： Olsen TS,Larsen B,Herning M,Skriver EB,Lassen NA

更新日期：1983-05-01 00:00:00

abstract：:The cardiac conditions most commonly associated with cerebral embolism are rheumatic heart disease (RHD), atherosclerotic heart disease (myocardial infarction and atrial arrhythmias) and other kinds of nonvalvular atrial fibillation (AF). The natural history of cerebral embolism from these cardiac sources is reviewed....

journal_title：Stroke

authors： Easton JD,Sherman DG

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A simple method of testing cerebral autoregulation by observing transcranial Doppler changes in middle cerebral artery flow velocity (FV) during a brief ipsilateral carotid artery compression (the transient hyperemic response test) was studied in 11 normal healthy volunteers. The aim of this stud...

journal_title：Stroke

authors： Smielewski P,Czosnyka M,Kirkpatrick P,McEroy H,Rutkowska H,Pickard JD

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulation of iron after intracerebral hemorrhage causes free radical formation and oxidative damage resulting in liquefaction. The aim of this study was the investigation of molecular mechanisms underlying estrogen-mediated neuroprotective effect against iron-induced brain injury in vivo. MET...

journal_title：Stroke

authors： Chen TY,Tsai KL,Lee TY,Chiueh CC,Lee WS,Hsu C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid plaque composition is a major determinant of cerebrovascular events. In the present analysis, we evaluated the relationship between intraplaque hemorrhage (IPH) and a thin/ruptured fibrous cap (TRFC) in moderately stenosed carotid arteries and cerebral infarcts on MRI in the ipsilateral h...

journal_title：Stroke

authors： de Rotte AA,Truijman MT,van Dijk AC,Liem MI,Schreuder FH,van der Kolk AG,de Kruijk JR,Daemen MJ,van der Steen AF,de Borst GJ,Luijten PR,Nederkoorn PJ,Kooi ME,van der Lugt A,Hendrikse J

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The migratory efficiency of mesenchymal stem cells (MSC) toward cerebral infarct after transplantation is limited. Valproate (VPA) and lithium enhance in vitro migration of MSC by upregulating CXC chemokine receptor 4 and matrix metalloproteinase-9, respectively. Ability of VPA and lithium to pro...

journal_title：Stroke

authors： Tsai LK,Wang Z,Munasinghe J,Leng Y,Leeds P,Chuang DM

更新日期：2011-10-01 00:00:00

abstract：:Recent data strongly suggest that repetitive ischemic episodes have an adverse cumulative effect on development of edema and tissue damage. We wanted to assess further whether special risks such as exacerbation of extracellular acidification reflecting progressive exhaustion of the capacity to buffer H+ in the extrace...

journal_title：Stroke

authors： Matsumoto T,Obrenovitch TP,Parkinson NA,Symon L

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Enlarged perivascular spaces (EPVS) have been associated with aging, increased stroke risk, decreased cognitive function, and vascular dementia. However, the relationship of EPVS with age-related neuropathologies is not well understood. Therefore, the purpose of this study was to assess the neuro...

journal_title：Stroke

authors： Javierre-Petit C,Schneider JA,Kapasi A,Makkinejad N,Tamhane AA,Leurgans SE,Mehta RI,Barnes LL,Bennett DA,Arfanakis K

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous tissue plasminogen activator (tPA) is an economically worthwhile but underused treatment option for acute ischemic stroke. We sought to identify the extent of tPA use in Canadian medical centers and the potential savings associated with increased use nationally and by province. METHO...

journal_title：Stroke

authors： Yip TR,Demaerschalk BM

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study evaluated the safety and efficacy of aggressive mechanical clot disruption (AMCD) in acute stroke patients with persisting middle cerebral artery (MCA) or internal carotid artery (ICA) occlusion after thrombolytic therapy. METHODS:Retrospective case series were used from a prospective...

journal_title：Stroke

authors： Noser EA,Shaltoni HM,Hall CE,Alexandrov AV,Garami Z,Cacayorin ED,Song JK,Grotta JC,Campbell MS 3rd

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The first goal of this study was to determine the effect of glutamate on permeability and reactivity of the cerebral microcirculation. The second goal of this study was to determine a possible role for nitric oxide in the effects of glutamate on the cerebral microcirculation. METHODS:We examined...

journal_title：Stroke

authors： Mayhan WG,Didion SP

更新日期：1996-05-01 00:00:00

abstract：:Five patients with nonseptic cerebral embolism of cardiac origin are reported in whom early anticoagulant therapy resulted in clinical deterioration or death from frank hemorrhage into the acute infarct. In each patient an initial CT scan excluded the presence of intracerebral hemorrhage and a second CT scan, after cl...

journal_title：Stroke

authors： Shields RW Jr,Laureno R,Lachman T,Victor M

更新日期：1984-05-01 00:00:00

abstract：:The hydrogen clearance method was used to measure local and total cerebral blood flow (CBF) in the rhesus monkey before and for five hours after a simulated subarachnoid hemorrhage (SAH). CBF remained stable after SAH unless SAH was associated with a fall in cerebral perfusion pressure. In addition, cerebrovascular re...

journal_title：Stroke

authors： Martins AN,Doyle TF,Newby N,Kobrine AI,Ramirez A

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from epidemiological and case-control studies suggest that increased total homocysteine (tHcy) levels are associated with increased risk for thromboembolic disease. The mechanisms by which hyperhomocysteinemia contributes to thrombogenesis are incompletely understood. The main objectives of ...

journal_title：Stroke

authors： Kristensen B,Malm J,Nilsson TK,Hultdin J,Carlberg B,Dahlén G,Olsson T

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial direct current stimulation is emerging as a promising tool for the treatment of several neurological conditions, including cerebral ischemia. The therapeutic role of this noninvasive treatment is, however, limited to chronic phases of stroke. We thus ought to investigate whether diff...

journal_title：Stroke

authors： Peruzzotti-Jametti L,Cambiaghi M,Bacigaluppi M,Gallizioli M,Gaude E,Mari S,Sandrone S,Cursi M,Teneud L,Comi G,Musco G,Martino G,Leocani L

更新日期：2013-11-01 00:00:00

abstract：:I provide the theoretical basis for an error calculus for measurements of cerebral blood flow using a freely diffusible tracer substance such as xenon-133. The use of the error calculus is exemplified by a study of the effect on the error margins in measurements of gray matter blood flow from flow level, relative weig...

journal_title：Stroke

authors： Ryding E

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess the dose-response relationship between vigorous physical activity (running distance, km/d) and the participant-reported physician-diagnosed stroke. METHODS:Age-adjusted survival analysis of 29 279 men and 12 123 women followed prospectively for 7.7 years. ...

journal_title：Stroke

authors： Williams PT

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...

journal_title：Stroke

authors： Chen H,Hu CJ,He YY,Yang DI,Xu J,Hsu CY

更新日期：2001-10-01 00:00:00

abstract：:The nature of alpha-adrenergic receptors in human cerebral arteries was characterized, and alteration of these receptors after subarachnoid hemorrhage was examined using a radioligand binding assay. Norepinephrine content of control arteries was also analyzed and compared with that of arteries after subarachnoid hemor...

journal_title：Stroke

authors： Tsukahara T,Taniguchi T,Miwa S,Shimohama S,Fujiwara M,Nishikawa M,Handa H

更新日期：1988-01-01 00:00:00

abstract：:In 24 patients with cerebrovascular disease and 6 without organic brain lesions, the increased velocity of blood flow in both the internal carotid and vertebral arteries during a contralateral carotid compression was compared with the angiographic appearance of the circle of Willis. The flow velocity was measured usin...

journal_title：Stroke

authors： Yoneda S,Nukada T,Kimura K,Tanaka K,Ashida K,Asai T,Etani H,Imaizumi M,Abe H

更新日期：1981-07-01 00:00:00

abstract：:Background and Purpose- To identify the specific post-endovascular stroke therapy (EVT) peak systolic blood pressure (SBP) threshold that best discriminates good from bad functional outcomes (a priori hypothesized to be 160 mm Hg), we conducted a prospective, multicenter, cohort study with a prespecified analysis plan...

journal_title：Stroke

authors： Mistry EA,Sucharew H,Mistry AM,Mehta T,Arora N,Starosciak AK,De Los Rios La Rosa F,Siegler JE 3rd,Barnhill NR,Patel K,Assad S,Tarboosh A,Dakay K,Salwi S,Cruz AS,Wagner J,Fortuny E,Bennett A,James RF,Jagadeesan B,S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS:As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at...

journal_title：Stroke

authors： Ballard C,Rowan E,Stephens S,Kalaria R,Kenny RA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is associated with a temporal pattern of stroke incidence. We hypothesized that natural oscillations in gene expression controlling circadian rhythm affect the severity of neuronal injury. We moreover predict that heme oxygenase-1 (HO-1/Hmox1) and its product carbon ...

journal_title：Stroke

authors： Schallner N,Lieberum JL,Gallo D,LeBlanc RH 3rd,Fuller PM,Hanafy KA,Otterbein LE

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The estimated prevalence of intracranial atherosclerotic disease (IAD) in patients with stenosis of the extracranial internal carotid artery (ICA) varies between 20% and 50%. The benefits of carotid endarterectomy (CE) in patients with both IAD and symptomatic extracranial ICA stenosis are uncert...

journal_title：Stroke

authors： Kappelle LJ,Eliasziw M,Fox AJ,Sharpe BL,Barnett HJ

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although both general and abdominal adiposity are well-established risk factors for coronary heart disease, their associations with stroke are less well characterized, particularly in generally lean Asian populations. METHODS:We evaluated associations of body mass index (BMI), waist-hip ratio (W...

journal_title：Stroke

authors： Zhang X,Shu XO,Gao YT,Yang G,Li H,Zheng W

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral amyloid angiopathy (CAA) occurs as a sporadic disorder in aged humans, as a frequent component of Alzheimer's disease, or in hereditary cerebral hemorrhage with amyloidosis (HCHWA). The primary histological locus of cerebral amyloid deposition varies in aged humans and in different speci...

journal_title：Stroke

authors： Wei LH,Walker LC,Levy E

更新日期：1996-11-01 00:00:00

abstract：:Background and Purpose- This ARISTOPHANES study (Anticoagulants for Reduction in Stroke: Observational Pooled Analysis on Health Outcomes and Experience of Patients) used multiple data sources to compare stroke/systemic embolism (SE) and major bleeding (MB) among a large number of nonvalvular atrial fibrillation patie...

journal_title：Stroke

authors： Lip GYH,Keshishian A,Li X,Hamilton M,Masseria C,Gupta K,Luo X,Mardekian J,Friend K,Nadkarni A,Pan X,Baser O,Deitelzweig S

更新日期：2018-12-01 00:00:00

abstract：:There have been numerous failures in the field of acute stroke therapy over many years, but the first large clinical trial showing preliminary indications of efficacy and safety of a neuroprotective drug, NXY-059, has now been fully reported. If confirmed, it will mean that a second therapy for acute stroke has been i...

journal_title：Stroke

authors： Zivin JA

更新日期：2007-02-01 00:00:00

abstract：:A randomized controlled trial was conducted to examine the effects of interdisciplinary team care on acute hospitalized stroke patients. After obtaining baseline information on 42 stroke victims receiving conventional care in a general hospital, 130 stroke patients were stratified and randomly assigned either to Tradi...

journal_title：Stroke

authors： Wood-Dauphinee S,Shapiro S,Bass E,Fletcher C,Georges P,Hensby V,Mendelsohn B

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of the present study was to evaluate the impact of basilar artery (BA) vasospasm on outcome in patients with severe vasospasm after aneurysmal subarachnoid hemorrhage (aSAH). METHODS:Sixty-five patients with clinically suspect severe cerebral vasospasm after aSAH underwent cerebral a...

journal_title：Stroke

authors： Sviri GE,Newell DW,Lewis DH,Douville C,Ghodke B,Chowdhary M,Lam AM,Haynor D,Zaaroor M,Britz GW

更新日期：2006-11-01 00:00:00