The incidence of cerebral venous thrombosis: a cross-sectional study.

abstract：BACKGROUND AND PURPOSE:The sensitivity of the brain to brief periods of profound ischemia or prolonged periods of modest ischemia mandates an aggressive approach to acute stroke care. Past studies have shown that many stroke patients do not receive acute care in an urgent and timely fashion. The formation of acute stro...

journal_title：Stroke

authors： Alberts MJ,Chaturvedi S,Graham G,Hughes RL,Jamieson DG,Krakowski F,Raps E,Scott P

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation and high polypharmacy are unknown. METHODS:We used Medicare administrative data to evaluate patients with new atrial fibrillation diagnosis from 2015 to 2017, who initiated an oral anticoagulant with...

journal_title：Stroke

authors： Mentias A,Heller E,Vaughan Sarrazin M

更新日期：2020-07-01 00:00:00

abstract：:Thromboxane synthetase activity is selectively inhibited by (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propenoic acid hydrochloride monohydrate (OKY-046). A single dose of 100 mg OKY-046 was orally administered to patients with ischemic cerebrovascular disease and healthy volunteers. Platelet aggregation and thromboxane B...

journal_title：Stroke

authors： Uyama O,Nagatsuka K,Nakabayashi S,Isaka Y,Yoneda S,Kimura K,Abe H

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Abnormalities in endogenous fibrinolysis are associated with an increased risk for stroke in men and older adults. We tested the hypothesis that elevated plasma tissue plasminogen activator (tPA) antigen, a marker for impaired endogenous fibrinolysis, is an independent risk factor for stroke in y...

journal_title：Stroke

authors： Macko RF,Kittner SJ,Epstein A,Cox DK,Wozniak MA,Wityk RJ,Stern BJ,Sloan MA,Sherwin R,Price TR,McCarter RJ,Johnson CJ,Earley CJ,Buchholz DW,Stolley PD

更新日期：1999-01-01 00:00:00

abstract：:The protective properties of PY 108-068 against ischemic disturbances in the brain were investigated in vitro and in vivo. The calcium antagonistic effects were demonstrated on isolated, calcium-loaded arterial rings of feline cerebral arteries. Determination of brain tissue oxygenation with pO2 microelectrodes showed...

journal_title：Stroke

authors： Wiernsperger N,Gygax P,Hofmann A

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:TIMI angiographic classification measures coronary residual flow and recanalization. We developed a Thrombolysis in Brain Ischemia (TIBI) classification by using transcranial Doppler (TCD) to noninvasively monitor intracranial vessel residual flow signals. We examined whether the emergent TCD TIB...

journal_title：Stroke

authors： Demchuk AM,Burgin WS,Christou I,Felberg RA,Barber PA,Hill MD,Alexandrov AV

更新日期：2001-01-01 00:00:00

abstract：:The goal of this study was to test the hypothesis that atherosclerosis alters responses of cerebral arteries and the ocular circulation to the activation in vivo of leukocytes and platelets. We measured blood flow to the brain and eye using microspheres and pressure in the cerebral microvessels of normal and atheroscl...

journal_title：Stroke

authors： Faraci FM,Lopez AG,Breese K,Armstrong ML,Heistad DD

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence of a relationship of fish intake to stroke incidence or mortality is weak. This report examines the association of fish consumption with stroke. METHODS:A cohort of 2107 men aged 40 to 55 years from the Chicago Western Electric Study who were free of coronary heart disease and stroke th...

journal_title：Stroke

authors： Orencia AJ,Daviglus ML,Dyer AR,Shekelle RB,Stamler J

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Obstructive sleep apnea, a condition associated with chronic intermittent hypoxia (CIH), carries an increased risk of stroke. However, CIH has been reported to either increase or decrease brain injury in models of focal cerebral ischemia. The factors determining the differential effects of CIH on...

journal_title：Stroke

authors： Jackman KA,Zhou P,Faraco G,Peixoto PM,Coleman C,Voss HU,Pickel V,Manfredi G,Iadecola C

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Toll-like receptors (TLRs) and the scavenger receptor CD36 are key molecular sensors for the innate immune response to invading pathogens. However, these receptors may also recognize endogenous "danger signals" generated during brain injury, such as cerebral ischemia, and trigger a maladaptive in...

journal_title：Stroke

authors： Abe T,Shimamura M,Jackman K,Kurinami H,Anrather J,Zhou P,Iadecola C

更新日期：2010-05-01 00:00:00

abstract：:A randomized controlled trial was conducted to examine the effects of interdisciplinary team care on acute hospitalized stroke patients. After obtaining baseline information on 42 stroke victims receiving conventional care in a general hospital, 130 stroke patients were stratified and randomly assigned either to Tradi...

journal_title：Stroke

authors： Wood-Dauphinee S,Shapiro S,Bass E,Fletcher C,Georges P,Hensby V,Mendelsohn B

更新日期：1984-09-01 00:00:00

abstract：:We measured cerebral blood flow and somatosensory evoked potentials during transient focal cerebral ischemia in cats to compare the effects of four commonly used anesthetic regimens: ketamine/fentanyl/N2O (fentanyl), pentobarbital, ketamine/alpha-chloralose (alpha-chloralose), and ketamine/halothane/N2O (halothane). S...

journal_title：Stroke

authors： Helfaer MA,Kirsch JR,Traystman RJ

更新日期：1990-05-01 00:00:00

abstract：:The purpose of this work was to study the contractile activity of intracerebral microarterioles and their sensitivity to the calcium antagonist nimodipine. Potassium depolarization evoked contraction and rhythmic activity that was blocked by nimodipine (IC50 0.08 nM). High concentrations of noradrenaline and prostagla...

journal_title：Stroke

authors： Godfraind T,Morel N,Dessy C

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The rarity of intracranial vascular malformations (IVMs) and the infrequency of their outcomes make large, prolonged cohort studies the best means to evaluate their frequency and prognosis. METHODS:The Scottish Intracranial Vascular Malformation Study (SIVMS) is a prototype prospective, populati...

journal_title：Stroke

authors： Al-Shahi R,Bhattacharya JJ,Currie DG,Papanastassiou V,Ritchie V,Roberts RC,Sellar RJ,Warlow CP,Scottish Intracranial Vascular Malformation Study Collaborators.

更新日期：2003-05-01 00:00:00

abstract：:Two hundred fifteen consecutive patients with cerebrovascular events were evaluated prospectively for the incidence and characteristics of headache. Of 163 patients able to communicate, headache occurred in 29% with bland infarcts, 57% with parenchymal hemorrhage, 36% with transient ischemic attacks and 17% with lacun...

journal_title：Stroke

authors： Portenoy RK,Abissi CJ,Lipton RB,Berger AR,Mebler MF,Baglivo J,Solomon S

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to investigate the feasibility and therapeutic effect of external counterpulsation (ECP) in ischemic stroke. METHODS:The trial was a randomized, crossover, assessment-blinded, proof-of-concept trial. ECP treatment consisted of 35 daily 1-hour sessions. Patients were randomized to either...

journal_title：Stroke

authors： Han JH,Leung TW,Lam WW,Soo YO,Alexandrov AW,Mok V,Leung YF,Lo R,Wong KS

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Experimental and clinical data suggest that insonation of echo-contrast agents with high acoustical power produces disintegration of microbubbles, resulting in a pseudo-Doppler phenomenon called stimulated acoustic emission (SAE). The purpose of this study was to investigate whether SAE might be ...

journal_title：Stroke

authors： Pohl C,Tiemann K,Schlosser T,Becher H

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to evaluate the efficacy of remote ischemic conditioning (RIC) in patients with cerebral small-vessel disease. METHODS:Thirty patients with cerebral small-vessel disease-related mild cognitive impairment were enrolled in this prospective, randomized controlled study for 1 year. Besides ...

journal_title：Stroke

authors： Wang Y,Meng R,Song H,Liu G,Hua Y,Cui D,Zheng L,Feng W,Liebeskind DS,Fisher M,Ji X

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The proteoglycan versican is an excellent candidate gene for intracranial aneurysms (IAs) because it plays an important role in extracellular matrix assembly and is localized in a previously implicated locus for IAs on chromosome 5q. METHODS:We analyzed all the common variations using 16-tag sin...

journal_title：Stroke

authors： Ruigrok YM,Rinkel GJ,Wijmenga C

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hemorrhagic conversion after tissue plasminogen activator (tPA) stroke therapy has been linked with elevations in matrix metalloproteinase-9 (MMP-9) at the neurovascular interface. Here, we test the idea that statins may directly ameliorate tPA-induced MMP-9 dysregulation. METHODS:Recombinant hu...

journal_title：Stroke

authors： Wang S,Lee SR,Guo SZ,Kim WJ,Montaner J,Wang X,Lo EH

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Large pulse pressure associates with atherosclerosis, but it is unclear if it contributes to the development of atherosclerosis or if atherosclerosis leads to pulse pressure widening. We examined whether exposure to large pulse pressure in childhood predicts carotid artery intima-media thickness ...

journal_title：Stroke

authors： Raitakari OT,Juonala M,Taittonen L,Jula A,Laitinen T,Kähönen M,Viikari JS

更新日期：2009-04-01 00:00:00

abstract：:An ocular pneumoplethysmograph was devised to measure the systolic pressure in the ophthalmic artery and to obtain calibrated pulse volume changes from the ocular globe, with simultaneous recording from both eyes. The instrument is self-contained and portable. It can be applied by paramedical personnel, and the graphi...

journal_title：Stroke

authors： Gee W,Oller DW,Wylie EJ

更新日期：1976-01-01 00:00:00

abstract：:U78517F is a novel inhibitor of iron-catalyzed lipid peroxidation that combines the tetramethylchroman antioxidant ring portion of alpha-tocopherol with the amine of the previously described 21-aminosteroids (e.g., U74006F). U78517F inhibited 200 microM FeCl2-initiated lipid peroxidation in rat brain homogenates by 50...

journal_title：Stroke

authors： Hall ED,Pazara KE,Braughler JM,Linseman KL,Jacobsen EJ

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess the association of vitamin D deficiency and indices of mineral metabolism with subclinical carotid markers that predict cardiovascular events. METHODS:Two hundred three community-dwelling adults (Northern Manhattan Study; age, 68 ± 11; age range, 50 to 93 ...

journal_title：Stroke

authors： Carrelli AL,Walker MD,Lowe H,McMahon DJ,Rundek T,Sacco RL,Silverberg SJ

更新日期：2011-08-01 00:00:00

abstract：:Background and Purpose- Case reports suggest that unruptured intracranial aneurysms may serve as a nidus for thrombus formation and downstream embolic stroke. However, few data exist to support an association between unruptured aneurysms and ischemic stroke. Methods- We conducted a within-subjects case-control study o...

journal_title：Stroke

authors： Chen ML,Gupta A,Chatterjee A,Khazanova D,Dou E,Patel H,Gialdini G,Merkler AE,Navi BB,Kamel H

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Epidemiological and laboratory studies suggest that increasing concentrations of plasma homocysteine (total homocysteine [tHcy]) accelerate cardiovascular disease by promoting vascular inflammation, endothelial dysfunction, and hypercoagulability. METHODS:We conducted a randomized controlled tri...

journal_title：Stroke

authors： Dusitanond P,Eikelboom JW,Hankey GJ,Thom J,Gilmore G,Loh K,Yi Q,Klijn CJ,Langton P,van Bockxmeer FM,Baker R,Jamrozik K

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of smoking reduction on cardiovascular disease outcomes has not been studied in Asian populations. METHODS:A total of 475 734 Korean men aged 30 to 58 years, stratified into 9 groups based on smoking status at 2 different time points (1990 and 1992), were followed from 1992 to 2001 fo...

journal_title：Stroke

authors： Song YM,Cho HJ

更新日期：2008-09-01 00:00:00

abstract：:The effect of ischemia on catecholamine and 5-hydroxytryptamine (5-HT) levels in brain cortex was examined in the gerbil stroke model. Unilateral common carotid artery occlusion produced bilateral decrease in cortical dopamine levels in gerbils both symptomatic and asymptomatic of cerbral ischemia. The 5-HT progressiv...

journal_title：Stroke

authors： Welch KM,Chabi E,Buckingham J,Bergin B,Achar VS,Meyer JS

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to clarify the association of chronic kidney disease (CKD) with carotid atherosclerosis and the impact of CKD on carotid atherosclerosis according to blood pressure categories in an urban general population. METHODS:We studied 3466 Japanese individuals (35-93 years old) in the Suita Stu...

journal_title：Stroke

authors： Ohara T,Kokubo Y,Toyoda K,Watanabe M,Koga M,Nakamura S,Nagatsuka K,Minematsu K,Nakagawa M,Miyamoto Y

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aspirin resistance may be relatively common and associated with adverse outcome. Meta-analysis has clearly shown that 75 mg plain aspirin is the lowest effective dose; however, it is not known whether the recent increased use of enteric-coated aspirin could account for aspirin resistance. This st...

journal_title：Stroke

authors： Cox D,Maree AO,Dooley M,Conroy R,Byrne MF,Fitzgerald DJ

更新日期：2006-08-01 00:00:00