Abstract:
BACKGROUND AND PURPOSE:The effect of smoking reduction on cardiovascular disease outcomes has not been studied in Asian populations. METHODS:A total of 475 734 Korean men aged 30 to 58 years, stratified into 9 groups based on smoking status at 2 different time points (1990 and 1992), were followed from 1992 to 2001 for the occurrence of stroke or myocardial infarction (MI) events. RESULTS:Compared with nonreducing heavy smokers (>/=20 cigarettes/d), those who quit smoking showed significantly lower risks of ischemic stroke, subarachnoid hemorrhage, and MI with hazard ratios (95% confidence intervals [CI]) of 0.66 (0.55 to 0.79), 0.58 (0.38 to 0.90), and 0.43 (0.34 to 0.53), respectively. For hemorrhagic stroke, quitters showed lower risk compared with heavy smokers, but the difference was not statistically significant (hazard ratio 0.82, 95% CI: 0.64 to 1.06). Compared with nonreducing heavy smokers, the risks of all stroke combined and MI among reducers tended to decrease, although the reductions were not statistically significant. The risks of subarachnoid hemorrhage and MI in those who reduced from moderate to light smoking tended to be lower than in nonreducing moderate (10 to 19 cigarettes/d) smokers. The association between the reduction of smoking level and the risk of stroke and MI did not change significantly when the analysis was limited to those whose smoking status in 1992 was maintained up to 1994. CONCLUSIONS:Smoking cessation was associated with a decrease in the risks of ischemic stroke, subarachnoid hemorrhage, and MI. More studies are needed to verify the likely health benefits of reducing smoking.
journal_name
Strokejournal_title
Strokeauthors
Song YM,Cho HJdoi
10.1161/STROKEAHA.107.512632subject
Has Abstractpub_date
2008-09-01 00:00:00pages
2432-8issue
9eissn
0039-2499issn
1524-4628pii
STROKEAHA.107.512632journal_volume
39pub_type
杂志文章相关文献
STROKE文献大全abstract::Recent data strongly suggest that repetitive ischemic episodes have an adverse cumulative effect on development of edema and tissue damage. We wanted to assess further whether special risks such as exacerbation of extracellular acidification reflecting progressive exhaustion of the capacity to buffer H+ in the extrace...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.8.1192
更新日期:1990-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previous research has reported worse outcomes after stroke for women and for African Americans, but few prospective population-based studies have systematically examined demographic differences on long-term stroke outcomes. Race and gender differences in 1-year stroke outcomes were examined using...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.595322
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Virtual reality (VR) is a new promising computer-assisted technology to promote motor recovery in stroke patients. VR-induced neuroplasticity supporting locomotor recovery is not known. We investigated the effects of VR intervention on cortical reorganization and associated locomotor recovery in ...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/01.STR.0000162715.43417.91
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The purpose of this study was to clarify whether mitral valve prolapse increases the subsequent risk of stroke. METHODS:A historical cohort study was conducted on 1079 residents of Olmsted County, Minnesota, who had an initial echocardiographic diagnosis of mitral valve prolapse between 1975 and...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.1.7
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Endothelin receptor antagonists such as clazosentan decrease large-artery vasospasm after experimental and clinical subarachnoid hemorrhage. We used clazosentan to gain insight into the pathophysiology of subarachnoid hemorrhage by determining if decreasing vasospasm is associated with alleviatio...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.604728
更新日期:2011-05-01 00:00:00
abstract::A 26-year-old woman had a peripartum venous thrombotic stroke involving the right parietal lobe. The initial thrombus was present only in the right channel of a congenitally bifurcated superior sagittal sinus. This diagnosis and subsequent thrombus extension were readily shown by magnetic resonance imaging in contrast...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.3.396
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Treatment of stroke patients in specialized stroke units has become more frequent, yet the effect of this treatment has not been determined. METHODS:In a community-based, prospective, and consecutive study of 1241 unselected acute stroke patients, we compared outcome of stroke treatment between ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.26.7.1178
更新日期:1995-07-01 00:00:00
abstract::Before surgery, we evaluated major intracranial collateral pathways using transcranial Doppler ultrasonography (TCD) in 50 patients who then underwent carotid endarterectomy with concurrent multimodality cerebral monitoring. Patients were grouped with respect to collateral pathways demonstrated preoperatively by TCD: ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.19.11.1328
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We have previously shown that 17beta-estradiol reduces infarction volume in female rats. The present study determined whether single injection or chronic implantation of estrogen confers neuroprotection in male animals with middle cerebral artery occlusion (MCAO) and whether there is an interacti...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.29.8.1666
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We sought to assess the long-term predictive usefulness of bone mineral density (BMD) for stroke incidence and stroke mortality. METHODS:The First National Health and Nutrition Examination Survey data were obtained from a nationally representative sample of noninstitutionalized civilians. A coho...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000065826.23815.A5
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We designed a prospective sequential pretreatment and posttreatment MRI study to assess the relation between neuroimaging parameters and clinical outcome in patients treated with intravenous recombinant tissue-type plasminogen activator (rtPA). METHODS:Patients with symptoms of acute hemispheric...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.0000053850.64877.af
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic str...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019395
更新日期:2018-01-01 00:00:00
abstract::The value of the concomittant use of a real time frequency analyzer along with a continuous wave carotid Doppler scanner is demonstrated in this study of 118 cases. With a colour-coded Doppler scanner alone, internal carotid stenoses greater than 35% were diagnosed with a sensitivity of 95% and a specificity of 82%. W...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.13.5.660
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The best management of patients with unruptured brain arteriovenous malformations (BAVM) is controversial. In this study, we analyzed the stroke rate and functional outcomes of patients having stereotactic radiosurgery (SRS) for unruptured BAVM using the same eligibility criteria and primary end ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.112.670232
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Functional stimulation is accompanied by increases in regional cerebral blood flow which exceed metabolic demands under normal circumstances, but it is unknown whether functional stimulation is beneficial or detrimental in the setting of acute ischemia. The aim of this study was to determine the ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000217305.82123.d8
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Neuroradiological characteristics and functional outcomes of patients with intracerebral hemorrhage (ICH) during novel oral anticoagulant treatment were not well defined. We examined these in comparison with those during warfarin treatment. METHODS:The consecutive 585 patients with ICH admitted ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.006661
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Evidence indicates that center volume of cases affects outcomes for both carotid endarterectomy and stenting. We evaluated the effect of enrollment volume by site on complication rates in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). METHODS:The primary composite en...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/STROKEAHA.114.006228
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this experiment was to study the serial changes in brain intracellular pH, cerebral blood flow, and the oxidation/reduction level of intramitochondrial nicotinamide adenine dinucleotide fluorescence across the cortical surface during severe incomplete global ischemia. METHODS:Reduced ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.3.435
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Stroke patients have a 15-fold increased risk of recurrent stroke, and those with > or =1 risk factor have a further increased risk of recurrence. Previous work found management of physiological risk factors after stroke to be unsatisfactory, but there is little information on behavioral risks wi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.31.8.1877
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Maternal cigarette smoking increases the risk of neonatal morbidity. We tested the hypothesis that perinatal nicotine exposure causes heightened brain vulnerability to hypoxic-ischemic (HI) injury in neonatal rats through aberrant expression patterns of angiotensin II type 1 (AT(1)R) and type 2 (...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.112.664698
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The treatment of large brain arteriovenous malformations (BAVMs) is challenging, and embolization alone is seldom curative. The study goal is to enhance the efficacy of arteriovenous malformation embolization by adding a beta-emitting isotope to the embolic agent. METHODS:The pig rete mirabile w...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000185673.73381.4c
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The impact of asymptomatic coronary artery disease on the risk of major vascular events in patients with cerebral infarction is unknown. METHODS:Four hundred five patients with acute cerebral infarction underwent carotid, femoral artery, thoracic, and abdominal aorta ultrasound examination. Of 3...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.000142
更新日期:2013-06-01 00:00:00
abstract::Clinical and pathologic observations have suggested analogies between the developing nervous system of ferrets (Mustela putorius furo) and those of more traditional animal models employed in stroke research. Experimental work has demonstrated advantages of the ferret as a model of visual development. We performed in v...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.8.1085
更新日期:1989-08-01 00:00:00
abstract::Thrombus formation is of paramount importance in the pathophysiology of acute ischemic stroke. Current antithrombotics used to treat or prevent cerebral ischemia are only moderately effective or bear an increased risk of severe bleeding. von Willebrand factor (VWF) has long been known to be a key player in thrombus fo...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/STROKEAHA.111.628867
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:The aim of the present study was to investigate the diagnostic potential of contrast-enhanced transcranial color-coded real-time sonography (CE-TCCS) in otherwise ultrasound-refractory acute stroke patients with an ischemia in the territory of the middle cerebral artery (MCA). Furthermore, correlations of CE-TC...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.9.1819
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several studies have reported a better functional outcome in lobar intracerebral hemorrhage (ICH) compared with deep location. However, among lobar ICH, a correlation of hemorrhage site-involving the specific lobes-with functional outcome has not been established. METHODS:Conservatively treated ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.015890
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Adequate control of blood pressure (BP) is a cornerstone in stroke prevention. This study explored the risk of stroke in relation to the quality of BP control in a population-based cohort and whether control of hypertension was related to background characteristics of patients. METHODS:A total o...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000158925.12740.87
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Recovery of patients within the first 6 months after stroke is well documented, but there has been little research on long-term recovery. The aim of this study was to analyze functional and motor recovery between admission to rehabilitation centres and 5 years after stroke. METHODS:This follow-u...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/STROKEAHA.115.009421
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Chinese patients largely experience acute ischemic stroke (AIS) because of large artery atherosclerosis rather than cardioembolism, and whether tirofiban is safe and effective in these patients treated with endovascular thrombectomy (ET) is unknown. This study evaluated the safety and efficacy of...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.019193
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The spontaneously hypertensive stroke-prone rat (SHRSP) is an animal model for a complex form of cerebrovascular pathology. MRI provides an efficient and noninvasive tool for studying the time course of brain damage. The aim of this study was to gain new insights into the pathological phenomena r...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/hs0302.104111
更新日期:2002-03-01 00:00:00