Characteristics of intracerebral hemorrhage during rivaroxaban treatment: comparison with those during warfarin.

abstract：BACKGROUND AND PURPOSE:We tested the hypothesis that intravenous administration of basic fibroblast growth factor (bFGF) during 4 hours of permanent focal ischemia would affect acute brain injury. METHODS:Halothane-anesthetized cats underwent left middle cerebral artery (MCA) occlusion for 4 hours. Control cats receiv...

journal_title：Stroke

authors： Bethel A,Kirsch JR,Koehler RC,Finklestein SP,Traystman RJ

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:With decision-analytic models becoming more popular to assess the cost-effectiveness of health care interventions, the need for robust estimates on the costs of cerebrovascular disease is paramount. This study reports the results from a literature review of the costs of cerebrovascular diseases, ...

journal_title：Stroke

authors： Luengo-Fernandez R,Gray AM,Rothwell PM

更新日期：2009-02-01 00:00:00

abstract：:Background and Purpose- Cerebral small vessel disease (SVD) is a major cause of stroke and dementia, but underlying disease mechanisms are still largely unknown, partly because of the difficulty in assessing small vessel function in vivo. We developed a method to measure blood flow velocity pulsatility in perforating ...

journal_title：Stroke

authors： Geurts LJ,Zwanenburg JJM,Klijn CJM,Luijten PR,Biessels GJ

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous work has shown that rates of cerebral microemboli downstream of high-grade internal carotid artery stenosis are higher in recently symptomatic compared with asymptomatic patients. In addition, microembolic rates decline after carotid endarterectomy. We conducted a prospective investigati...

journal_title：Stroke

authors： Sitzer M,Müller W,Siebler M,Hort W,Kniemeyer HW,Jäncke L,Steinmetz H

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several studies have reported poor outcomes in patients too good to treat with intravenous thrombolysis because of mild or rapidly improving symptoms. We sought to determine baseline clinical and imaging predictors of poor outcome in these patients. METHODS:Among 3950 consecutive stroke admissio...

journal_title：Stroke

authors： Ali SF,Siddiqui K,Ay H,Silverman S,Singhal A,Viswanathan A,Rost N,Lev M,Schwamm LH

更新日期：2016-12-01 00:00:00

abstract：:Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...

journal_title：Stroke

authors： White RP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Pediatric National Institutes of Health Stroke Scale (PedNIHSS), an adaptation of the adult National Institutes of Health Stroke Scale, is a quantitative measure of stroke severity shown to be reliable when scored prospectively. The ability to calculate the PedNIHSS score retrospectively woul...

journal_title：Stroke

authors： Beslow LA,Kasner SE,Smith SE,Mullen MT,Kirschen MP,Bastian RA,Dowling MM,Lo W,Jordan LC,Bernard TJ,Friedman N,DeVeber G,Kirton A,Abraham L,Licht DJ,Jawad AF,Ellenberg JH,Lautenbach E,Ichord RN

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:One hundred twelve patients undergoing elective carotid endarterectomy for symptomatic and asymptomatic carotid artery stenosis were enrolled in a prospective study to evaluate the incidence of change in postoperative cerebral function. METHODS:Patients were evaluated preoperatively and postoper...

journal_title：Stroke

authors： Heyer EJ,Adams DC,Solomon RA,Todd GJ,Quest DO,McMahon DJ,Steneck SD,Choudhri TF,Connolly ES

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The independent contribution of insulin resistance to atherosclerosis is still under debate. We compared associations of 2 different indices of insulin resistance, the Homeostasis Model Assessment (HOMA) index and kITT from a short insulin tolerance test with carotid atherosclerosis. METHODS:A t...

journal_title：Stroke

authors： Sourij H,Schmoelzer I,Dittrich P,Paulweber B,Iglseder B,Wascher TC

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several observations indicate that, during energy deprivation, endogenous dopamine may become neurotoxic. Accordingly, the nucleus striatum is a preferential site of silent infarcts in humans, and experimental ischemia caused by homolateral carotid occlusion selectively damages this dopamine-enri...

journal_title：Stroke

authors： Saulle E,Centonze D,Martín AB,Moratalla R,Bernardi G,Calabresi P

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The integrin-linked kinase (ILK) signaling pathway contributes to regulation of cellular adhesion, migration, and differentiation, and to apoptotic cell death after a variety of cell death stimuli. We have reported that overexpression of copper/zinc superoxide dismutase (SOD1) reduces apoptotic c...

journal_title：Stroke

authors： Saito A,Hayashi T,Okuno S,Nishi T,Chan PH

更新日期：2004-11-01 00:00:00

abstract：:A 55-year-old woman with an aortic arch syndrome of acute onset and dysphasia, resulting from the excessive administration of ergotamine tartrate suppositories, is described. Complete resolution of symptoms and return of upper limb and carotid artery pulses to normal occurred within four days of cessation of the ergot...

journal_title：Stroke

authors： Feneley MP,Morgan JJ,McGrath MA,Egan JD

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Epidemiological studies have shown mixed findings on the association between hypertension and stroke in the oldest old. Heterogeneity of the populations under study may underlie variation in outcomes. We examined whether the level of physical and cognitive function moderates the association betwe...

journal_title：Stroke

authors： Sabayan B,van Vliet P,de Ruijter W,Gussekloo J,de Craen AJ,Westendorp RG

更新日期：2013-01-01 00:00:00

abstract：:Many patients suffer a stroke early after a transient ischemic attack, but the reason why is often unclear. We studied 12 patients with less than 75% stenosis of the internal carotid artery and a single hemispheric transient ischemic attack lasting less than 1 hour who had a normal neurologic examination 3-13 hours la...

journal_title：Stroke

authors： Bogousslavsky J,Delaloye-Bischof A,Regli F,Delaloye B

更新日期：1990-01-01 00:00:00

abstract：:It is generally stated that ulceration of the carotid bifurcation plaque may give rise to embolization and symptoms of cerebral ischemia. It has been suggested that prophylactic carotid endarterectomy is indicated in asymptomatic patients if the angiogram is interpreted as showing ulceration. We therefore determined t...

journal_title：Stroke

authors： Eikelboom BC,Riles TR,Mintzer R,Baumann FG,DeFillip G,Lin J,Imparato AM

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysregulation of vessel wall formation, growth, and maintenance may confer susceptibility of stroke. METHODS:We tested the hypothesis that variants in 2 genes encoding vascular endothelial growth factor and vascular endothelial growth factor receptor-2 are associated with susceptibility to strok...

journal_title：Stroke

authors： Zhang W,Sun K,Zhen Y,Wang D,Wang Y,Chen J,Xu J,Hu FB,Hui R

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Disruption of the endothelial layer is the first step in the atherogenic process. Experimental studies have shown that endothelial progenitor cells (EPCs) are involved in endothelial homeostasis and repair. Conversely, EPC depletion has been demonstrated in the setting of established atherosclero...

journal_title：Stroke

authors： Fadini GP,Coracina A,Baesso I,Agostini C,Tiengo A,Avogaro A,de Kreutzenberg SV

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion-weighted MRI can demonstrate decreases of the apparent diffusion coefficient (ADC) of brain tissue water shortly after the onset of ischemia. To further elucidate underlying mechanisms, this study extended diffusion assessment to intracellular metabolites in rat brain in vivo before, du...

journal_title：Stroke

authors： Wick M,Nagatomo Y,Prielmeier F,Frahm J

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) is a devastating disease without a proven therapy to improve long-term outcome. Considerable controversy about the role of surgery remains. Minimally invasive endoscopic surgery for ICH offers the potential of improved neurological outcome. METHODS:We tested the hy...

journal_title：Stroke

authors： Vespa P,Hanley D,Betz J,Hoffer A,Engh J,Carter R,Nakaji P,Ogilvy C,Jallo J,Selman W,Bistran-Hall A,Lane K,McBee N,Saver J,Thompson RE,Martin N,ICES Investigators.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:NINDS (National Institute of Neurological Disorders and Stroke)-SiGN (Stroke Genetics Network) is an international consortium of ischemic stroke studies that aims to generate high-quality phenotype data to identify the genetic basis of pathogenic stroke subtypes. This analysis characterizes the e...

journal_title：Stroke

authors： Ay H,Arsava EM,Andsberg G,Benner T,Brown RD Jr,Chapman SN,Cole JW,Delavaran H,Dichgans M,Engström G,Giralt-Steinhauer E,Grewal RP,Gwinn K,Jern C,Jimenez-Conde J,Jood K,Katsnelson M,Kissela B,Kittner SJ,Kleindorfer D

更新日期：2014-12-01 00:00:00

abstract：:The purpose of this study was to develop an animal model that could be used to test the ability of Doppler ultrasound to detect arterial emboli composed of materials that are often involved in cerebral emboli. Emboli introduced into the rabbit aorta via the left renal artery consisted of clotted whole blood, platelets...

journal_title：Stroke

authors： Russell D,Madden KP,Clark WM,Sandset PM,Zivin JA

更新日期：1991-02-01 00:00:00

abstract：:We have evaluated carotid gamma imaging using 111Indium-labelled platelets in the diagnosis of carotid artery disease and measured the accumulation of labelled platelets on endarterectomy specimens. Autologous 111In labelled platelets were injected in 25 patients with TIA. Gamma images were then taken daily and indepe...

journal_title：Stroke

authors： Goldman M,Leung JO,Aukland A,Hawker RJ,Drolc Z,McCollum CN

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with stroke and transient ischemic attack (TIA) often have comparable comorbidities, but it is unclear whether they have similar rates of depression or antidepressant use. METHODS:This study was a secondary analysis of a prospective cohort registry that enrolled subjects from 2006 to 20...

journal_title：Stroke

authors： El Husseini N,Goldstein LB,Peterson ED,Zhao X,Pan W,Olson DM,Zimmer LO,Williams JW Jr,Bushnell C,Laskowitz DT

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated low density lipoprotein and reduced high density lipoprotein cholesterol may increase the risk of atherothrombotic brain infarction, but the metabolic mechanisms accounting for this relation are poorly understood. METHODS:The kinetic parameters of low density and high density lipoprotei...

journal_title：Stroke

authors： Alam R,Yatsu FM,Kasturi R,Bui G

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of flow diverter (FD) on hemodynamic changes observed in aneurysms is inevitably affected by the actual structural configuration of deployed FD. We studied the resultant hemodynamic changes after implantation of FDs using computational fluid dynamic simulations based on micro-computed ...

journal_title：Stroke

authors： Huang Q,Xu J,Cheng J,Wang S,Wang K,Liu JM

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Single and multiple lacunar infarctions may have some difference in underlying diseases and cerebral blood flows. To determine the difference, we investigated underlying diseases and cerebral blood flows in single and multiple lacunar infarctions. METHODS:Fifteen cases of lacunar infarction, 10 ...

journal_title：Stroke

authors： Mochizuki Y,Oishi M,Takasu T

更新日期：1997-07-01 00:00:00

abstract：:Cerebral cortical blood flow was measured in rabbits with the hydrogen clearance technique. The reactivity to CO2, tested by changing the end tidal CO2 (ETCO2) in steps from 2 to 6 volumes %, was highly dependent on the kind of anesthesia, being greatest under halothane and least under nitrous oxide. Reactivity to CO2...

journal_title：Stroke

authors： Scremin OU,Rubinstein EH,Sonnenschein RR

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This prospective study was aimed to evaluate the effects of surgical revascularization on cerebral oxygen metabolism in moyamoya disease. METHODS:This study included totally 69 hemispheres of 42 patients who underwent superficial temporal artery to middle cerebral artery anastomosis and indirect...

journal_title：Stroke

authors： Kuroda S,Kashiwazaki D,Hirata K,Shiga T,Houkin K,Tamaki N

更新日期：2014-09-01 00:00:00

abstract：:Twenty-four cats had an intravenous infusion of either Fluosol or saline and then were subjected to 2 hours of middle cerebral artery occlusion. All the animals infused with Fluosol and one-half the animals infused with saline were ventilated with 100% O2. Tissue oxygen availability and regional cerebral blood flow we...

journal_title：Stroke

authors： Kolluri S,Heros RC,Hedley-Whyte ET,Vonsattel JP,Miller D,Zervas NT

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vascular effects of mental stress are only partially understood. Therefore, we studied effects of chronic stress and heart rate (HR) on endothelial function and cerebral ischemia. METHODS:129S6/SvEv mice were randomized to the I(f)-channel inhibitor ivabradine (10 mg/kg per day) or vehicle and u...

journal_title：Stroke

authors： Custodis F,Gertz K,Balkaya M,Prinz V,Mathar I,Stamm C,Kronenberg G,Kazakov A,Freichel M,Böhm M,Endres M,Laufs U

更新日期：2011-06-01 00:00:00