Genomewide linkage in a large Caucasian family maps a new locus for intracranial aneurysms to chromosome 13q.

abstract：:In the rat an intracisternal injection of blood induces an angiographically demonstrable biphasic cerebral arterial vasospasm. Chemical destruction of the central serotoninergic and dopaminergic pathways prior to the cisternal blood injection does not affect the spasm pattern after the subarachnoid haemorrhage. It is ...

journal_title：Stroke

authors： Svendgaard NA,Brismar J,Delgado TJ,Rosengren E,Stenevi U

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microwave Radiometry (MWR) allows in vivo noninvasive assessment of internal temperature of tissues. The aim of the present study was to evaluate in patients with ischemic stroke and bilateral carotid plaques (1) whether ipsilateral carotid arteries exhibit higher temperature differences (ΔT), as...

journal_title：Stroke

authors： Toutouzas K,Benetos G,Drakopoulou M,Deligianni C,Spengos K,Stefanadis C,Siores E,Tousoulis D

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:We sought to determine interrater agreement in evaluation of stroke patients with the Unified Form for Neurological Stroke Scales (UFNSS). SUMMARY OF REPORT:Fifty inpatients were independently examined by three neurologists. Kendall coefficients of concordance were computed for the different items of the UF...

journal_title：Stroke

authors： Treves TA,Karepov VG,Aronovich BD,Gorbulev AY,Bornstein NM,Korczyn AD

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mechanical thrombectomy (MT) is the recommended treatment for acute ischemic stroke caused by anterior circulation large vessel occlusion. However, despite a high rate of reperfusion, the clinical response to successful MT remains highly variable in the early time window where optimal imaging sel...

journal_title：Stroke

authors： Olivot JM,Albucher JF,Guenego A,Thalamas C,Mlynash M,Rousseau V,Drif A,Christensen S,Sommet A,Viguier A,Darcourt J,Calvière L,Menegon P,Raposo N,Januel AC,Bonneville F,Tourdias T,Mazighi M,Sibon I,Albers GW,Cognar

更新日期：2021-01-01 00:00:00

abstract：:Adenylate cyclase activity was investigated in either homogenate or particulate fractions from the frontal cerebral cortex of the gerbil following five experimental conditions of bilateral ischemia. After periods of 15 min ischemia, 15 min ischemia plus 15 min of recirculation or 60 min ischemia the enzyme generally d...

journal_title：Stroke

authors： Taylor MD,Palmer GC,Callahan AS 3rd

更新日期：1984-03-01 00:00:00

abstract：:Background and Purpose- The simplified stroke-thrombolytic predictive instrument (s-Stroke-TPI) is useful for predicting the outcomes in thrombolysis-treated patients in Western populations. We aimed to validate its predictive value in Chinese patients. Methods- Data from thrombolysis implementation and monitor of acu...

journal_title：Stroke

authors： Wang C,Yang Y,Pan Y,Liao X,Huo X,Miao Z,Wang Y,Wang Y

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Emergency medical services routing of patients with acute stroke to designated centers may increase the proportion of patients receiving care at facilities meeting national standards and augment recruitment for prehospital stroke research. METHODS:We analyzed consecutive patients enrolled within...

journal_title：Stroke

authors： Sanossian N,Liebeskind DS,Eckstein M,Starkman S,Stratton S,Pratt FD,Koenig W,Hamilton S,Kim-Tenser M,Conwit R,Saver JL,FAST-MAG Investigators and Coordinators.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We hypothesize that reversal in diffusion-weighted imaging (DWI) volume at 24 hours predicts favorable clinical outcome only if accompanied by immediate reperfusion. Our aim was to quantify the immediate DWI and mean transit time changes at 2 and 24 hours after intravenous tissue-type plasminogen...

journal_title：Stroke

authors： Luby M,Warach SJ,Nadareishvili Z,Merino JG

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke risk increases with age in patients who have nonvalvular atrial fibrillation. It is uncertain whether the efficacy of stroke prevention therapies in atrial fibrillation changes as patients age. The objective of this study was to determine the effect of age on the relative efficacy of oral ...

journal_title：Stroke

authors： van Walraven C,Hart RG,Connolly S,Austin PC,Mant J,Hobbs FD,Koudstaal PJ,Petersen P,Perez-Gomez F,Knottnerus JA,Boode B,Ezekowitz MD,Singer DE

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains uncertain whether lower dose intravenous tissue-type plasminogen activator (tPA) for stroke is as effective and safe as the standard dose. METHODS:We analyzed data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China). Patients who were treate...

journal_title：Stroke

authors： Liao X,Wang Y,Pan Y,Wang C,Zhao X,Wang DZ,Wang C,Liu L,Wang Y,Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Symptomatic intracranial hemorrhage (SICH) is the most feared complication after tissue plasminogen activator (tPA) stroke treatment. Endogenous fibrinolysis inhibitors play an essential role in the coagulation/fibrinolysis balance and may be involved in the bleeding process. We aim to determine ...

journal_title：Stroke

authors： Ribo M,Montaner J,Molina CA,Arenillas JF,Santamarina E,Quintana M,Alvarez-Sabín J

更新日期：2004-09-01 00:00:00

abstract：:The postischemic production of PGE2, PGD2, 6-keto-PGF1 alpha, and TXB2 in brain tissue was studied in Mongolian gerbils using tissue extraction as well as a new ex vivo method. This new method permits the study of prostaglandin synthesis in slices from discrete areas of the brain (cortex, hippocampus, striatum, hypoth...

journal_title：Stroke

authors： Kempski O,Shohami E,von Lubitz D,Hallenbeck JM,Feuerstein G

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Spreading depressions (SDs) occur in experimental focal ischemia and contribute to lesion evolution. N-Methyl-D-aspartate (NMDA) antagonists inhibit SDs and reduce infarct size. The glycine site on the NMDA receptor complex offers a therapeutic target for acute focal ischemia, potentially devoid ...

journal_title：Stroke

authors： Tatlisumak T,Takano K,Meiler MR,Fisher M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A right-to-left shunt can be identified by contrast transcranial Doppler ultrasonography (c-TCD) at rest and/or after a Valsalva maneuver (VM) or by arterial blood gas (ABG) measurement. We assessed the influence of controlled strain pressures and durations during VM on the right-to-left passage ...

journal_title：Stroke

authors： Devuyst G,Piechowski-Józwiak B,Karapanayiotides T,Fitting JW,Kémeny V,Hirt L,Urbano LA,Arnold P,van Melle G,Despland PA,Bogousslavsky J

更新日期：2004-04-01 00:00:00

abstract：:Various studies indicate that after a latent interval, a progressive focal deterioration of microvascular perfusion can develop in zones of acute damage to the central nervous system (CNS). In order to obtain reliable information concerning the possibility of platelet participation in this phenomenon, platelet deposit...

journal_title：Stroke

authors： Obrenovitch TP,Hallenbeck JM

更新日期：1985-03-01 00:00:00

abstract：:Non-invasive vascular testing has proven to be an effective means of identifying patients with significant extracranial carotid artery disease. Such tests can yield valuable physiologic data in patients with TIAs and can identify patients with soft signs who may have significant carotid artery disease and who may be c...

journal_title：Stroke

authors： Goran A,Moore G

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Type 2 diabetes is associated with a high cardiovascular morbidity and mortality. Recent advances of intervention studies in type 2 diabetes with use of carotid intima-media thickness (CIMT) measurement as a surrogate end point may allow for better understanding of the undetermined process of ath...

journal_title：Stroke

authors： Yokoyama H,Katakami N,Yamasaki Y

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Desaturation during swallowing may help to identify aspiration in stroke patients. This study investigated pulse oximetry, bedside swallowing assessment (BSA), and videofluoroscopy as tests for detecting aspiration after stroke. METHODS:Swallowing was assessed in 189 stroke patients (mean+/-SD a...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perioperative strokes (POS) are rare but serious complications for which mechanical thrombectomy could be beneficial. We aimed to compare the technical results and patients outcomes in a population of POS versus non-POS (nPOS) treated by mechanical thrombectomy. METHODS:From 2010 to 2017, 25 pat...

journal_title：Stroke

authors： Premat K,Clovet O,Frasca Polara G,Shotar E,Bartolini B,Yger M,Di Maria F,Baronnet F,Pistocchi S,Le Bouc R,Pires C,Sourour N,Alamowitch S,Samson Y,Degos V,Clarençon F

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The natural history of stroke is worse in women than in men. Controversial data have been published on the efficacy of thrombolysis with recombinant tissue plasminogen activator (rtPA) according to gender. We evaluated gender differences in the efficacy and safety outcomes of intravenous rtPA usi...

journal_title：Stroke

authors： Meseguer E,Mazighi M,Labreuche J,Arnaiz C,Cabrejo L,Slaoui T,Guidoux C,Olivot JM,Abboud H,Lapergue B,Raphaeli G,Klein IF,Lavallée PC,Amarenco P

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative stress is known to be involved in ischemic stroke. Intense interest is drawn to the therapeutic potential of Chinese herbs on ischemic stroke because many of them contain antioxidant properties. Leonurine, 1 of the active compounds from purified Herba Leonuri, was studied to evaluate it...

journal_title：Stroke

authors： Loh KP,Qi J,Tan BK,Liu XH,Wei BG,Zhu YZ

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined whether hemodynamic and metabolic abnormalities in the cerebral white matter, basal ganglia, and thalamus are associated with asymptomatic white matter lesions (WML) depicted on MR images. METHODS:A positron emission tomographic study with H2(15)O, C15O, and 15O2 was performed in eig...

journal_title：Stroke

authors： Hatazawa J,Shimosegawa E,Satoh T,Toyoshima H,Okudera T

更新日期：1997-10-01 00:00:00

abstract：:Eighteen patients with recent ischemic stroke were compared with an equal number of matched controls. Standardized suspensions of red cells as well as of red and white cells were filtered in a new filtration apparatus capable of discriminating between cell deformability and filter occlusion. Results show that red cell...

journal_title：Stroke

authors： Ernst E,Matrai A,Paulsen F

更新日期：1987-01-01 00:00:00

abstract：:Brain injury, including ischemia, changes normal astrocytes into reactive species that hypertrophy and begin to proliferate. Understanding the mechanisms that underlie these changes could lead to new abilities to promote regeneration and retard neural degeneration after ischemia. Because ionic changes occur after nonn...

journal_title：Stroke

authors： Kraig RP,Jaeger CB

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Endovascular treatment of intracranial aneurysms is safe and effective but too often is followed by recurrences. Gene therapy may improve healing after embolization, and endovascular approaches may offer future in situ delivery systems designed to prevent aneurysm rupture. SUMMARY OF REVIEW:Advances in coil...

journal_title：Stroke

authors： Ribourtout E,Raymond J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the stroke rate associated with atrial fibrillation has declined over the last 10 years, the emerging atrial fibrillation epidemic threatens to increase the incidence of cardioembolic stroke. Summary of Review-Oral anticoagulants are superior antithrombotic agents but are underused due t...

journal_title：Stroke

authors： Medi C,Hankey GJ,Freedman SB

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The chronological development and natural history of cerebral aneurysms (CAs) remain incompletely understood. We used (14)C birth dating of a main constituent of CAs, that is, collagen type I, as an indicator for biosynthesis and turnover of collagen in CAs in relation to human cerebral arteries ...

journal_title：Stroke

authors： Etminan N,Dreier R,Buchholz BA,Beseoglu K,Bruckner P,Matzenauer C,Torner JC,Brown RD Jr,Steiger HJ,Hänggi D,Macdonald RL

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Uric acid (UA) is a neuroprotective antioxidant that improves the benefits of alteplase in experimental ischemia. However, it is unknown whether endogenous UA also influences the response to thrombolysis in patients with stroke. METHODS:A total of 317 consecutive patients treated with thrombolys...

journal_title：Stroke

authors： Amaro S,Urra X,Gómez-Choco M,Obach V,Cervera A,Vargas M,Torres F,Rios J,Planas AM,Chamorro A

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There have been relatively few community-based studies of long-term prognosis after acute stroke. This study aimed to provide precise estimates of the absolute and relative risks of dying in an unselected cohort of patients with a first-ever stroke. METHODS:Six hundred seventy-five patients were...

journal_title：Stroke

authors： Dennis MS,Burn JP,Sandercock PA,Bamford JM,Wade DT,Warlow CP

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to describe the clinical and imaging features of patients with tumor-like presentation of primary angiitis of the central nervous system. METHODS:We retrospectively analyzed 10 patients enrolled in the French primary angiitis of the central nervous system cohort, who initially presented...

journal_title：Stroke

authors： de Boysson H,Boulouis G,Dequatre N,Godard S,Néel A,Arquizan C,Detante O,Bloch-Queyrat C,Zuber M,Touzé E,Bienvenu B,Aouba A,Guillevin L,Naggara O,Pagnoux C,French Vasculitis Study Group.

更新日期：2016-09-01 00:00:00