Platelet accumulation in regions of low blood flow during the postischemic period.

abstract：BACKGROUND AND PURPOSE:Standard radiographic criteria for hematoma enlargement have not been established. We undertook this investigation to assess the incidence and time course of hematoma growth using objective cutoff values. METHODS:We reviewed the clinical records of 204 patients with spontaneous intracerebral hem...

journal_title：Stroke

authors： Kazui S,Naritomi H,Yamamoto H,Sawada T,Yamaguchi T

更新日期：1996-10-01 00:00:00

abstract：:Background and Purpose- Although obesity is an established risk factor for cardiovascular disease and stroke, studies have shown evidence of an obesity paradox-a protective effect of obesity in patients who already have these disease states. Data on the obesity paradox in intracerebral hemorrhage is limited. Methods- ...

journal_title：Stroke

authors： Persaud SR,Lieber AC,Donath E,Stingone JA,Dangayach NS,Zhang X,Mocco J,Kellner CP

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Many studies associate fever with poor outcome in patients with neurological injury, but this relationship is blurred by divergence in populations and outcome measures. We sought to incorporate all recent scholarship addressing fever in brain-injured patients into a comprehensive meta-analysis to...

journal_title：Stroke

authors： Greer DM,Funk SE,Reaven NL,Ouzounelli M,Uman GC

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this investigation was to compare the respective efficacy of transcranial Doppler sonography (TCD) and magnetic resonance angiography (MRA) for the assessment of intracranial hemodynamics in patients with extracranial occlusion or severe stenosis of the internal carotid artery (ICA). ...

journal_title：Stroke

authors： Anzola GP,Gasparotti R,Magoni M,Prandini F

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The rarity of intracranial vascular malformations (IVMs) and the infrequency of their outcomes make large, prolonged cohort studies the best means to evaluate their frequency and prognosis. METHODS:The Scottish Intracranial Vascular Malformation Study (SIVMS) is a prototype prospective, populati...

journal_title：Stroke

authors： Al-Shahi R,Bhattacharya JJ,Currie DG,Papanastassiou V,Ritchie V,Roberts RC,Sellar RJ,Warlow CP,Scottish Intracranial Vascular Malformation Study Collaborators.

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is no consensus on whether anticoagulation should be continued or temporarily stopped in patients suffering acute ischemic stroke while using anticoagulation. We assessed treatment variations and outcomes in these patients. METHODS:Post hoc analysis of PASS (Preventive Antibiotics in Strok...

journal_title：Stroke

authors： Groot AE,Vermeij JM,Westendorp WF,Nederkoorn PJ,van de Beek D,Coutinho JM

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chronic ocular ischemia is a rare form of ischemia of the eye in patients with carotid artery occlusion (CAO). The early and often asymptomatic stage of chronic ocular ischemia is referred to as venous stasis retinopathy (VSR). The aim of this study was to gain insight into the prevalence, cause,...

journal_title：Stroke

authors： Klijn CJ,Kappelle LJ,van Schooneveld MJ,Hoppenreijs VP,Algra A,Tulleken CA,van Gijn J

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vorapaxar is an antiplatelet agent that antagonizes thrombin-mediated activation of the protease-activated receptor-1 on platelets. We tested the efficacy and safety of vorapaxar in a prespecified analysis in the stroke subcohort from a multinational, randomized, placebo-controlled trial. METHOD...

journal_title：Stroke

authors： Morrow DA,Alberts MJ,Mohr JP,Ameriso SF,Bonaca MP,Goto S,Hankey GJ,Murphy SA,Scirica BM,Braunwald E,Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events–TIMI 50 Steering Committee and Investigators

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is the leading cause of disability in the Western world; however, few therapies are at hand to decrease this burden. SUMMARY OF REVIEW:Endothelial progenitor cells (EPCs) have been introduced in cardiovascular medicine as factotums. EPCs can repair damaged endothelium and attenuate the de...

journal_title：Stroke

authors： Rouhl RP,van Oostenbrugge RJ,Damoiseaux J,Tervaert JW,Lodder J

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sonic hedgehog (Shh) protein is required for the maintenance of neural progenitor cells (NPCs) in the embryonic and adult hippocampus. Brain ischemia causes increased proliferation of hippocampal NPCs. We therefore examined whether Shh regulates the increase in proliferation of NPCs after ischemi...

journal_title：Stroke

authors： Sims JR,Lee SW,Topalkara K,Qiu J,Xu J,Zhou Z,Moskowitz MA

更新日期：2009-11-01 00:00:00

abstract：:Using transesophageal echocardiography, cardiac structures can be imaged with high resolution. The aim of our study was to evaluate whether transesophageal echocardiography is superior in detecting mitral valve prolapse and other cardiac abnormalities compared with transthoracic echocardiography in an age-matched cont...

journal_title：Stroke

authors： Zenker G,Erbel R,Krämer G,Mohr-Kahaly S,Drexler M,Harnoncourt K,Meyer J

更新日期：1988-03-01 00:00:00

abstract：:Background and Purpose- The GLX (glycocalyx) is a protein/polysaccharide meshwork at the cellular surface. Consisting largely of glycosaminoglycans and proteoglycans, the GLX can shed in response to stress. In this study, we assay 11 components of the GLX in plasma from patients with ischemic stroke from a longitudina...

journal_title：Stroke

authors： DellaValle B,Hasseldam H,Johansen FF,Iversen HK,Rungby J,Hempel C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The apparent diffusion coefficient (ADC) of water should be sensitive to the cytotoxic edema triggered by energy failure during ischemia. Elevated values of T2. the nuclear MR transverse relaxation time of water, seen on T2 nuclear MR images detect vasogenic edema and infarcted areas. The tempora...

journal_title：Stroke

authors： Loubinoux I,Volk A,Borredon J,Guirimand S,Tiffon B,Seylaz J,Méric P

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Animal studies have shown that MR diffusion imaging can outline acute ischemic regions before irreversible damage (infarction) occurs. To study evolution of ischemic lesions in humans, it is therefore important to quantify absolute diffusion constants (D values), but quantitation has not been rep...

journal_title：Stroke

authors： Uluğ AM,Beauchamp N Jr,Bryan RN,van Zijl PC

更新日期：1997-03-01 00:00:00

abstract：:Leukoaraiosis is a common finding in stroke patients and has been strongly associated with risk of incident stroke and dementia. Leukoaraiosis may also be an independent predictor of stroke outcomes. There is increasing evidence from neuroimaging to support the concept that some leukoaraiosis is caused by white matter...

journal_title：Stroke

authors： Smith EE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transient ischemic attack (TIA) initiates an ischemic cascade without resulting in frank infarction and, as such, represents a novel model to study the effects of this ischemic cascade and secondary neurodegeneration in humans. METHODS:Patients with suspected TIA underwent acute brain perfusion ...

journal_title：Stroke

authors： Bivard A,Lillicrap T,Maréchal B,Garcia-Esperon C,Holliday E,Krishnamurthy V,Levi CR,Parsons M

更新日期：2018-02-01 00:00:00

abstract：:A 25-year-old black man with sarcoidosis presented with transient ischemic attacks followed by sudden, persistent right hemiparesis. He gave a history of recent, recurrent lower motor neuron facial palsy. Computed tomography demonstrated an infarct in the left internal capsule. Chest x-ray film showed bilateral hilar ...

journal_title：Stroke

authors： Brown MM,Thompson AJ,Wedzicha JA,Swash M

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The overall burden of prior infections may contribute to atherosclerosis and stroke risk. We hypothesized that serological evidence of common infections would be associated with carotid plaque thickness in a multiethnic cohort. METHODS:Antibody titers to 5 common infectious microorganisms (ie, C...

journal_title：Stroke

authors： Elkind MS,Luna JM,Moon YP,Boden-Albala B,Liu KM,Spitalnik S,Rundek T,Sacco RL,Paik MC

更新日期：2010-03-01 00:00:00

abstract：:The postischemic production of PGE2, PGD2, 6-keto-PGF1 alpha, and TXB2 in brain tissue was studied in Mongolian gerbils using tissue extraction as well as a new ex vivo method. This new method permits the study of prostaglandin synthesis in slices from discrete areas of the brain (cortex, hippocampus, striatum, hypoth...

journal_title：Stroke

authors： Kempski O,Shohami E,von Lubitz D,Hallenbeck JM,Feuerstein G

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated leukocyte count has been associated with cardiovascular and cerebrovascular disease in several epidemiological studies. We sought to determine whether white blood cell count (WBC) is associated with carotid plaque thickness in a stroke-free, multiethnic cohort. METHODS:For this cross-se...

journal_title：Stroke

authors： Elkind MS,Cheng J,Boden-Albala B,Paik MC,Sacco RL,Northern Manhattan Stroke Study.

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from prospective studies on the associations between B vitamin plasma levels and the risk of stroke are limited. We investigated the individual and combined effects of plasma folate, vitamin B12, and pyridoxal 5-phosphate (PLP) levels on the risk of ischemic stroke and transient ischemic att...

journal_title：Stroke

authors： Weikert C,Dierkes J,Hoffmann K,Berger K,Drogan D,Klipstein-Grobusch K,Spranger J,Möhlig M,Luley C,Boeing H

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral emboli can be identified by the presence of typical microembolic signals (MES) in transcranial Doppler (TCD) spectral curves. The usefulness of this technique was studied by evaluating the prevalence and time course of MES in patients with acute stroke. In addition, we examined the influ...

journal_title：Stroke

authors： Sliwka U,Lingnau A,Stohlmann WD,Schmidt P,Mull M,Diehl RR,Noth J

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:White matter (WM) is less vulnerable to ischemia than gray matter. In ischemic stroke caused by acute large-vessel occlusion, successful recanalization might therefore sometimes selectively salvage the WM, leading to infarct patterns confined to gray matter. This study examines occurrence, determ...

journal_title：Stroke

authors： Kleine JF,Kaesmacher M,Wiestler B,Kaesmacher J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some studies have suggested a link between impaired cerebral hemodynamics and stroke in patients with carotid stenosis. The aim of this study was to assess the effects of severe carotid stenosis on cerebrovascular reactivity and the possible changes after endarterectomy. METHODS:Using bilateral ...

journal_title：Stroke

authors： Silvestrini M,Troisi E,Matteis M,Cupini LM,Caltagirone C

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Proven behavioral assessment strategies for testing potential therapeutic agents in rat stroke models are needed. Few studies include tasks that demand higher levels of sensorimotor and cognitive function. Because behavioral outcome and rate of recovery vary among ischemia models, there is a need...

journal_title：Stroke

authors： Roof RL,Schielke GP,Ren X,Hall ED

更新日期：2001-11-01 00:00:00

abstract：:Endovascular acute ischemic stroke therapy is now proven by randomized controlled trials to produce large, clinically meaningful benefits. In response, stroke systems of care must change to increase timely and equitable access to this therapy. In this review, we provide a North American perspective on implications for...

journal_title：Stroke

authors： Smith EE,Schwamm LH

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acetazolamide is commonly used with single-photon CT to assess the cerebrovascular reserve in patients with internal carotid artery stenosis or occlusion. In this study we wanted to evaluate the effects of adenosine, a well-known vasodilatatory compound with a short biological half-life, on brain...

journal_title：Stroke

authors： Soricelli A,Postiglione A,Cuocolo A,De Chiara S,Ruocco A,Brunetti A,Salvatore M,Ell PJ

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). The relationship between genetic variation in the LPA gene region and CAAD risk remains unknown. METHODS:we genotyped single nucleotide polymorphisms (...

journal_title：Stroke

authors： Ronald J,Rajagopalan R,Cerrato F,Nord AS,Hatsukami T,Kohler T,Marcovina S,Heagerty P,Jarvik GP

更新日期：2011-01-01 00:00:00

abstract：:We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

journal_title：Stroke

authors： Rosenblum WI,Segreti AC

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The impact of anesthesia technique on the outcomes of mechanical thrombectomy for acute ischemic stroke remains an issue of debate. We investigated the association of general anesthesia with outcomes in patients undergoing mechanical thrombectomy for ischemic stroke. METHODS:We performed a cohor...

journal_title：Stroke

authors： Bekelis K,Missios S,MacKenzie TA,Tjoumakaris S,Jabbour P

更新日期：2017-02-01 00:00:00