Transient Ischemic Attack Results in Delayed Brain Atrophy and Cognitive Decline.

abstract：BACKGROUND AND PURPOSE:The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine-induced reduction in blood pressure (BP) and an unfavorable outcome in acute stroke. We sought to confirm this correlation with and without adjustment for prognostic variables and to investigate ...

journal_title：Stroke

authors： Ahmed N,Näsman P,Wahlgren NG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The presence of known restriction fragment length polymorphisms in the apoprotein A-I-C-III gene cluster, which encodes their respective apoproteins, was investigated using the restriction enzymes Sac I and Pst I to determine the potential role of genetic variations for stroke risk in an American...

journal_title：Stroke

authors： Kasturi R,Yatsu FM,Alam R,Rogers S

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To estimate the effect of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors ("statins") on stroke ris, we combined the data of the randomized, placebo-controlled, double-blind trials with HMG-CoA reductase inhibitors published so far. METHODS:The studies were identified using ...

journal_title：Stroke

authors： Blauw GJ,Lagaay AM,Smelt AH,Westendorp RG

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Short-term elevations in fine particulate matter air pollution (PM2.5) are associated with increased risk of acute cerebrovascular events. Evidence from the peripheral circulation suggests that vascular dysfunction may be a central mechanism. However, the effects of PM2.5 on cerebrovascular funct...

journal_title：Stroke

authors： Wellenius GA,Boyle LD,Wilker EH,Sorond FA,Coull BA,Koutrakis P,Mittleman MA,Lipsitz LA

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Leukocytes have been implicated in the development of ischemic atherosclerotic vascular diseases. In a prospective study we investigated whether the plasma concentrations of inflammatory mediators, ie, proteases and cytokines, as markers for systemic leukocyte activation, are increased in patient...

journal_title：Stroke

authors： Elneihoum AM,Falke P,Axelsson L,Lundberg E,Lindgärde F,Ohlsson K

更新日期：1996-10-01 00:00:00

abstract：:Functional assessment of animals following experimental cerebral ischemia is often difficult due to the passive nature of many neurologic exams. We attempted to increase the objectivity of motor function evaluation by adapting quantifiable behavioral tests and actively testing rats' motor capability following a cerebr...

journal_title：Stroke

authors： Combs DJ,D'Alecy LG

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The physiological function of cellular prion protein (PrPc) is not yet understood. Recent findings suggest that PrPc may have neuroprotective properties, and its absence increases susceptibility to neuronal injury. The purpose of this study was to elucidate the role of PrPc in ischemic brain inju...

journal_title：Stroke

authors： Weise J,Sandau R,Schwarting S,Crome O,Wrede A,Schulz-Schaeffer W,Zerr I,Bähr M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Physical and psychological characteristics in adolescence are associated with subsequent stroke risk. Our aim is to investigate their relevance to length of hospital stay and risk of second stroke. METHODS:Swedish men born between 1952 and 1956 (n=237 879) were followed from 1987 to 2010 using i...

journal_title：Stroke

authors： Bergh C,Udumyan R,Appelros P,Fall K,Montgomery S

更新日期：2016-09-01 00:00:00

abstract：:In a randomized pilot study we compared the efficacy of temporary anticoagulation with intravenous heparin sodium to the efficacy of aspirin in preventing cerebral infarction in hospitalized patients with recent (less than 7 days) transient ischemic attacks (TIAs). Fifty-five patients (33 men, 22 women) aged 36-81 (me...

journal_title：Stroke

authors： Biller J,Bruno A,Adams HP Jr,Godersky JC,Loftus CM,Mitchell VL,Banwart KJ,Jones MP

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Using the dexamethasone suppression test, we studied the suppressibility of the cortisol axis and its clinical determinants at various time points after stroke. A major aim was to examine the dexamethasone test as a diagnostic tool for the diagnosis of major depression in stroke patients. METHOD...

journal_title：Stroke

authors： Aström M,Olsson T,Asplund K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Animal data suggest the use of beta-human chorionic gonadotropin followed by erythropoietin to promote brain repair after stroke. The current study directly translated these results by evaluating safety of this sequential growth factor therapy through a 3-center, single-dose, open-label, noncontr...

journal_title：Stroke

authors： Cramer SC,Fitzpatrick C,Warren M,Hill MD,Brown D,Whitaker L,Ryckborst KJ,Plon L

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Efforts at public education to improve adults' response to stroke symptoms continue to be disappointing, and very little has been developed to improve the knowledge base of children regarding brain attacks. Children may be able to exert a positive influence on adult behavior and to learn positive...

journal_title：Stroke

authors： Dressman LA,Hunter J

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:beta-Blockers prevent vascular events in patients after myocardial infarction and lower blood pressure, the main risk factor for stroke. Hence, we assessed the effects of atenolol on the occurrence of death from vascular causes, stroke, or myocardial infarction and on blood pressure in patients a...

journal_title：Stroke

authors：

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Standard radiographic criteria for hematoma enlargement have not been established. We undertook this investigation to assess the incidence and time course of hematoma growth using objective cutoff values. METHODS:We reviewed the clinical records of 204 patients with spontaneous intracerebral hem...

journal_title：Stroke

authors： Kazui S,Naritomi H,Yamamoto H,Sawada T,Yamaguchi T

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral infarction (DCI) is an important cause of poor outcome after subarachnoid hemorrhage. Cerebral perfusion is a predictor for DCI. Because acute hydrocephalus may impair cerebral perfusion, we evaluated the predictive value of the extent of acute hydrocephalus on the development of...

journal_title：Stroke

authors： Bakker AM,Dorhout Mees SM,Algra A,Rinkel GJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS:As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at...

journal_title：Stroke

authors： Ballard C,Rowan E,Stephens S,Kalaria R,Kenny RA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Nonaneurysmal perimesencephalic hemorrhage, a distinct form of subarachnoid hemorrhage, is a recently described variant of intracranial hemorrhage. We describe two patients who presented with unusual features of this type of subarachnoid hemorrhage and also two patients who had a perimesencephalic pattern of...

journal_title：Stroke

authors： Schievink WI,Wijdicks EF,Piepgras DG,Nichols DA,Ebersold MJ

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vertebrobasilar territory ischemia (VBI) leads to disabling neurological symptoms and poses a risk for stroke by an embolic or flow-related mechanism. We present our clinical experience in the endovascular treatment of patients with symptomatic VBI from severe atherosclerosis or dissection of the...

journal_title：Stroke

authors： Malek AM,Higashida RT,Phatouros CC,Lempert TE,Meyers PM,Gress DR,Dowd CF,Halbach VV

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombin, heme oxygenase, complement, microglia activation, and leukocyte infiltration are all actively upregulated in intracerebral hemorrhage (ICH). Experimental evidence suggests that all these factors are involved in ICH-induced brain injury. This suggests a scenario whereby ICH actively (thr...

journal_title：Stroke

authors： Keep RF,Xi G,Hua Y,Hoff JT

更新日期：2005-07-01 00:00:00

abstract：:Background and Purpose- This ARISTOPHANES study (Anticoagulants for Reduction in Stroke: Observational Pooled Analysis on Health Outcomes and Experience of Patients) used multiple data sources to compare stroke/systemic embolism (SE) and major bleeding (MB) among a large number of nonvalvular atrial fibrillation patie...

journal_title：Stroke

authors： Lip GYH,Keshishian A,Li X,Hamilton M,Masseria C,Gupta K,Luo X,Mardekian J,Friend K,Nadkarni A,Pan X,Baser O,Deitelzweig S

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. MATERIALS AND METHODS:In the Swedish national quality assessment register, Riks-Stroke, 15 747 stroke sur...

journal_title：Stroke

authors： Eriksson M,Asplund K,Glader EL,Norrving B,Stegmayr B,Terént A,Asberg KH,Wester PO,Riks-Stroke Collaboration.

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autonomic nervous system diseases affect systemic blood pressure regulation. Patients with autonomic nervous system diseases have consistently larger drops in blood pressure associated with standing than the normal population. Autonomic dysfunction and/or these changes in blood pressure may affec...

journal_title：Stroke

authors： Blaber AP,Bondar RL,Stein F,Dunphy PT,Moradshahi P,Kassam MS,Freeman R

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We evaluated the impact of admission hyperglycemia (HG) on stroke outcome in relation to the timing of reperfusion in patients treated with tissue plasminogen activator (tPA). METHODS:We studied 138 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with...

journal_title：Stroke

authors： Alvarez-Sabín J,Molina CA,Ribó M,Arenillas JF,Montaner J,Huertas R,Santamarina E,Rubiera M

更新日期：2004-11-01 00:00:00

abstract：:During perinatal asphyxia, cerebral blood flow is markedly reduced in the gray and white matter of the telencephalon. Since previous work has implicated prostaglandins in the control of blood flow, we tested the hypothesis that a thromboxane synthesis inhibitor would improve cerebral blood flow and blunt the metabolic...

journal_title：Stroke

authors： Ment LR,Stewart WB,Petroff OA,Duncan CC

更新日期：1989-06-01 00:00:00

abstract：:Background and Purpose- Hyperacute assessment and management of patients with stroke, termed code stroke, is a time-sensitive and high-stakes clinical scenario. In the context of the current coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus, the ability to deliver timely and efficacious care ...

journal_title：Stroke

authors： Khosravani H,Rajendram P,Notario L,Chapman MG,Menon BK

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in the elderly. We undertook an international survey to characterize the frequency of AF-associated stroke, methods of AF detection, and patient features. METHODS:Consecutive patie...

journal_title：Stroke

authors： Perera KS,Vanassche T,Bosch J,Swaminathan B,Mundl H,Giruparajah M,Barboza MA,O'Donnell MJ,Gomez-Schneider M,Hankey GJ,Yoon BW,Roxas A Jr,Lavallee P,Sargento-Freitas J,Shamalov N,Brouns R,Gagliardi RJ,Kasner SE,Pieroni

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Systemic administration of Toll-like receptor (TLR) 4 and TLR9 agonists before cerebral ischemia have been shown to reduce ischemic injury by reprogramming the response of the brain to stroke. Our goal was to explore the mechanism of TLR-induced neuroprotection by determining whether a TLR7 agoni...

journal_title：Stroke

authors： Leung PY,Stevens SL,Packard AE,Lessov NS,Yang T,Conrad VK,van den Dungen NN,Simon RP,Stenzel-Poore MP

更新日期：2012-05-01 00:00:00

abstract：:The trends in age adjusted and age and sex specific mortality rates for the period 1968-1980 are compared for ischaemic heart disease and cerebrovascular disease. For both sexes and at all ages over 45 the mortality rates for cerebrovascular disease have fallen significantly. However, the mortality rates for ischaemic...

journal_title：Stroke

authors： Haberman S,Capildeo R,Rose FC

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess the prevalence and characteristics of silent cerebral infarction in a population-based consecutive autopsy series of residents of Hisayama, Kyushu, Japan. METHODS:Autopsy records, cerebral pathological findings, and clinical charts of 966 Hisayama resident...

journal_title：Stroke

authors： Shinkawa A,Ueda K,Kiyohara Y,Kato I,Sueishi K,Tsuneyoshi M,Fujishima M

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The onset of spontaneous intracerebral hemorrhage (ICH) is often accompanied by transient blood pressure (BP) elevation. The prognostic value and the determinants of this BP reaction have not entirely been solved, and the present study was focused on these questions. METHODS:From 1985 to 1991 in...

journal_title：Stroke

authors： Fogelholm R,Avikainen S,Murros K

更新日期：1997-07-01 00:00:00