Perimesencephalic subarachnoid hemorrhage. Additional perspectives from four cases.

abstract：BACKGROUND AND PURPOSE:Stroke produces diaschisis in adjacent and connected regions. The sequential changes in diaschisis over time and the relationship of regions of diaschisis to functional cortical areas and regions of poststroke neuroplasticity have not been determined. METHODS:Small cortical strokes were produced...

journal_title：Stroke

authors： Carmichael ST,Tatsukawa K,Katsman D,Tsuyuguchi N,Kornblum HI

更新日期：2004-03-01 00:00:00

abstract：:Background and Purpose- Ischemic stroke impairs endoplasmic reticulum (ER) function, causes ER stress, and activates the unfolded protein response. The unfolded protein response consists of 3 branches controlled by ER stress sensor proteins, which include PERK (protein kinase RNA-like ER kinase). Activated PERK phosph...

journal_title：Stroke

authors： Wang YC,Li X,Shen Y,Lyu J,Sheng H,Paschen W,Yang W

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Collateral flow augmentation using partial aortic occlusion may improve cerebral perfusion in acute stroke. We assessed the safety and feasibility of partial aortic occlusion immediately after intravenous tissue plasminogen activator. METHODS:We conducted an open-label pilot study of partial aor...

journal_title：Stroke

authors： Emery DJ,Schellinger PD,Selchen D,Douen AG,Chan R,Shuaib A,Butcher KS

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In 6% to 9% of patients with subarachnoid hemorrhage (SAH), familial aggregation occurs; truly familial cases carry a worse prognosis than sporadic cases and raise the question of screening. If relatives have died from SAH, the family history is often the only available clue to the diagnosis, but...

journal_title：Stroke

authors： Bromberg JE,Rinkel GJ,Algra A,Greebe P,Beldman T,van Gijn J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Effects of anoxic stress on cerebrovascular responses to calcitonin gene-related peptide (CGRP) have not been examined previously. We determined the effects of total global ischemia on cerebral arteriolar responses to CGRP in newborn pigs. METHODS:Piglets were anesthetized and ventilated with a ...

journal_title：Stroke

authors： Louis TM,Meng W,Bari F,Errico RA,Busija DW

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The proteoglycan versican is an excellent candidate gene for intracranial aneurysms (IAs) because it plays an important role in extracellular matrix assembly and is localized in a previously implicated locus for IAs on chromosome 5q. METHODS:We analyzed all the common variations using 16-tag sin...

journal_title：Stroke

authors： Ruigrok YM,Rinkel GJ,Wijmenga C

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Tacrolimus, an immunosuppressant agent, has been shown to reduce tissue injury and leukocyte accumulation after transient ischemia. This study was designed to evaluate quantitatively the inhibitory effects of tacrolimus on leukocyte rolling and on subsequent leukocyte accumulation in vivo after t...

journal_title：Stroke

authors： Tsujikawa A,Ogura Y,Hiroshiba N,Miyamoto K,Kiryu J,Honda Y

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional stimulation is accompanied by increases in regional cerebral blood flow which exceed metabolic demands under normal circumstances, but it is unknown whether functional stimulation is beneficial or detrimental in the setting of acute ischemia. The aim of this study was to determine the ...

journal_title：Stroke

authors： Burnett MG,Shimazu T,Szabados T,Muramatsu H,Detre JA,Greenberg JH

更新日期：2006-05-01 00:00:00

abstract：:We produced cerebral vasospasm in 29 dogs by the "two-hemorrhage" method of intracisternal injections, 2 days apart, of autogenous arterial blood. Leukotriene (LT) C4, LTD4, and LTE4 were purified from incubated basilar artery, medulla oblongata, hypothalamus, median eminence, and blood clot from around the basilar ar...

journal_title：Stroke

authors： Yokota M,Tani E,Maeda Y

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anecdotal evidence suggests that the coronavirus disease 2019 (COVID-19) pandemic mitigation efforts may inadvertently discourage patients from seeking treatment for stroke with resultant increased morbidity and mortality. Analysis of regional data, while hospital capacities for acute stroke care...

journal_title：Stroke

authors： Hsiao J,Sayles E,Antzoulatos E,Stanton RJ,Sucharew H,Broderick JP,Demel SL,Flaherty ML,Grossman AW,Kircher C,Kreitzer N,Peariso K,Prestigiacomo CJ,Shirani P,Walsh KB,Lampton H,Adeoye O,Khatri P

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of the cerebral microcirculation in delayed ischemia after subarachnoid hemorrhage remains obscure. To test the hypothesis that cerebral arterioles have a reduced capacity to dilate after subarachnoid hemorrhage, we studied the microvascular responses to papaverine (PPV) in patients unde...

journal_title：Stroke

authors： Pennings FA,Albrecht KW,Muizelaar JP,Schuurman PR,Bouma GJ

更新日期：2009-01-01 00:00:00

abstract：:An anecdotal series of nine patients (three men and six women with an average age of 57 years) presented with progressive neurologic deterioration while on medical therapy for large right hemispheric cerebral infarction. Clinical signs of uncal herniation (anisocoria or fixed and dilated pupils, and/or left hemiplegia...

journal_title：Stroke

authors： Delashaw JB,Broaddus WC,Kassell NF,Haley EC,Pendleton GA,Vollmer DG,Maggio WW,Grady MS

更新日期：1990-06-01 00:00:00

abstract：:We studied 1,273 patients with ischemic cerebral infarction who were entered into the Stroke Data Bank, a prospective, observational study involving four university hospitals and the Biometry and Field Studies Branch of the National Institute of Neurological Disorders and Stroke. Forty patients had noniatrogenic recur...

journal_title：Stroke

authors： Sacco RL,Foulkes MA,Mohr JP,Wolf PA,Hier DB,Price TR

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The spontaneously hypertensive stroke-prone rat (SHRSP) is an animal model for a complex form of cerebrovascular pathology. MRI provides an efficient and noninvasive tool for studying the time course of brain damage. The aim of this study was to gain new insights into the pathological phenomena r...

journal_title：Stroke

authors： Guerrini U,Sironi L,Tremoli E,Cimino M,Pollo B,Calvio AM,Paoletti R,Asdente M

更新日期：2002-03-01 00:00:00

abstract：:The purpose of this work was to study the contractile activity of intracerebral microarterioles and their sensitivity to the calcium antagonist nimodipine. Potassium depolarization evoked contraction and rhythmic activity that was blocked by nimodipine (IC50 0.08 nM). High concentrations of noradrenaline and prostagla...

journal_title：Stroke

authors： Godfraind T,Morel N,Dessy C

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to identify quantitative trait loci (QTL) for carotid intima-media thickness (CIMT) a risk factor for stroke and cardiovascular disease. METHODS:Probands were selected from Caribbean Hispanic subjects of the population-based Northern Manhattan Study. CIMT was measured b...

journal_title：Stroke

authors： Sacco RL,Blanton SH,Slifer S,Beecham A,Glover K,Gardener H,Wang L,Sabala E,Juo SH,Rundek T

更新日期：2009-07-01 00:00:00

abstract：:Background and Purpose- The purpose of this study was to assess recent trends in the admission and mortality rates for subarachnoid hemorrhage in Canada. Methods- This retrospective cross-sectional study was based on data retrieved from the Canadian Institute for Health Information for all patients diagnosed with suba...

journal_title：Stroke

authors： Chan V,Lindsay P,McQuiggan J,Zagorski B,Hill MD,O'Kelly C

更新日期：2018-11-21 00:00:00

abstract：BACKGROUND AND PURPOSE:The presence of white-matter hyperintensities (WMHs) has been linked to intracerebral hemorrhage (ICH). We sought to determine whether the severity of WMHs influences hematoma growth and ICH volume. METHODS:We retrospectively reviewed prospectively collected clinical, laboratory, and radiologic ...

journal_title：Stroke

authors： Lou M,Al-Hazzani A,Goddeau RP Jr,Novak V,Selim M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Proven behavioral assessment strategies for testing potential therapeutic agents in rat stroke models are needed. Few studies include tasks that demand higher levels of sensorimotor and cognitive function. Because behavioral outcome and rate of recovery vary among ischemia models, there is a need...

journal_title：Stroke

authors： Roof RL,Schielke GP,Ren X,Hall ED

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clomethiazole is a neuroprotective drug that enhances gamma-aminobutyrate type A (GABA(A)) receptor activity. Its efficacy and safety were tested in the CLomethiazole Acute Stroke Study (CLASS). The protocol allowed a CT scan to be done after randomization but within 7 days of stroke onset to min...

journal_title：Stroke

authors： Wahlgren NG,Díez-Tejedor E,Teitelbaum J,Arboix A,Leys D,Ashwood T,Grossman E

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Parental stroke has been related to an increased risk of stroke in the offspring. This study examines whether parental stroke is also associated with increased vascular brain injury and poorer cognitive performance among offspring free of clinical stroke. METHODS:Multivariable regression analyse...

journal_title：Stroke

authors： Weinstein G,Beiser AS,Au R,Decarli C,Wolf PA,Seshadri S

更新日期：2013-03-01 00:00:00

abstract：:Brain injury, including ischemia, changes normal astrocytes into reactive species that hypertrophy and begin to proliferate. Understanding the mechanisms that underlie these changes could lead to new abilities to promote regeneration and retard neural degeneration after ischemia. Because ionic changes occur after nonn...

journal_title：Stroke

authors： Kraig RP,Jaeger CB

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hemodynamic insult by bilateral common carotid artery ligation has been shown to induce aneurysmal remodeling at the basilar terminus in a rabbit model. To characterize critical hemodynamics that initiate this remodeling, we applied a novel hemodynamics-histology comapping technique. METHODS:Eig...

journal_title：Stroke

authors： Metaxa E,Tremmel M,Natarajan SK,Xiang J,Paluch RA,Mandelbaum M,Siddiqui AH,Kolega J,Mocco J,Meng H

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There have been few community-based studies of long-term prognosis after acute stroke. This study aims to provide precise estimates of the absolute and relative risks of stroke recurrence in an unselected cohort of patients with a first-ever stroke. METHODS:Six hundred seventy-five patients were...

journal_title：Stroke

authors： Burn J,Dennis M,Bamford J,Sandercock P,Wade D,Warlow C

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Inflammatory and immune mechanisms can precipitate cerebrovascular thrombosis and hemorrhage. Immunologic tolerance can be induced to a specific antigen by intranasal instillation of that antigen. Lymphocytes tolerized in this way provide local immunosuppression on restimulation with the same ant...

journal_title：Stroke

authors： Takeda H,Spatz M,Ruetzler C,McCarron R,Becker K,Hallenbeck J

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The best management of patients with unruptured brain arteriovenous malformations (BAVM) is controversial. In this study, we analyzed the stroke rate and functional outcomes of patients having stereotactic radiosurgery (SRS) for unruptured BAVM using the same eligibility criteria and primary end ...

journal_title：Stroke

authors： Pollock BE,Link MJ,Brown RD

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathogenesis of periventricular hyperintensity (PVH) is still uncertain. We investigated the relationship between PVH and risk factors for cerebrovascular diseases, especially extracranial carotid artery stenosis (ECAS). METHODS:We studied PVH and ECAS in 323 subjects between 1991 and 1994. ...

journal_title：Stroke

authors： Adachi T,Takagi M,Hoshino H,Inafuku T

更新日期：1997-11-01 00:00:00

abstract：:Background and Purpose- Accurate prediction of the subsequent infarct volume early after stroke onset helps determine appropriate interventions and prognosis. In the DEFUSE 3 trial (Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke), we evaluated the accuracy of baseline ischemic core and hypoperfu...

journal_title：Stroke

authors： Rao V,Christensen S,Yennu A,Mlynash M,Zaharchuk G,Heit J,Marks MP,Lansberg MG,Albers GW

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...

journal_title：Stroke

authors： McHutchison C,Blair GW,Appleton JP,Chappell FM,Doubal F,Bath PM,Wardlaw JM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and is linked with mortality, cardiovascular events, and stroke. However, the role of FGF23 as a risk factor for subclinical cerebrovascular damage is unclear. METHODS:We used multivariable linear and logistic regressio...

journal_title：Stroke

authors： Wright CB,Shah NH,Mendez AJ,DeRosa JT,Yoshita M,Elkind MS,Sacco RL,DeCarli C,Rundek T,Silverberg S,Dong C,Wolf M

更新日期：2016-04-01 00:00:00