Determinants of early recurrence of cerebral infarction. The Stroke Data Bank.

abstract：:Regional cerebral ischemia was produced by common carotid artery occlusion in gerbils and by middle cerebral artery occlusion in dogs, cats, and squirrel monkeys. Anesthesia was induced with either pentobarbital or halothane and maintained for two to three hours after vessel occlusion. In acute studies, the effect of ...

journal_title：Stroke

authors： Michenfelder JD,Milde JH

更新日期：1975-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vasogenic brain edema is a frequent complication of ischemic stroke. The mechanism of the blood-brain barrier opening that underlies the edema formation is poorly understood. In the present study we examined the response of endothelial cells cultured from adult human brain to thrombogenic and fib...

journal_title：Stroke

authors： Nagy Z,Kolev K,Csonka E,Pék M,Machovich R

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the resting regional cerebral blood flow (rCBF) in aphasic patients has been thoroughly investigated with positron emission tomography (PET) and single-photon emission CT, and PET studies in normal subjects have elucidated the functional localization of language processing, little is kno...

journal_title：Stroke

authors： Ohyama M,Senda M,Kitamura S,Ishii K,Mishina M,Terashi A

更新日期：1996-05-01 00:00:00

abstract：UNLABELLED:Background and Purpose-Hemiplegic shoulder pain is not uncommon after stroke. Its origin is still unknown, and although many different methods of treatment are applied, none have yet been proved to be effective. We sought to study the efficacy of 3 injections of intra-articular triamcinolone acetonide on pai...

journal_title：Stroke

authors： Snels IA,Beckerman H,Twisk JW,Dekker JH,Peter De Koning,Koppe PA,Lankhorst GJ,Bouter LM

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...

journal_title：Stroke

authors： Woodward M,Lowe GD,Campbell DJ,Colman S,Rumley A,Chalmers J,Neal BC,Patel A,Jenkins AJ,Kemp BE,MacMahon SW

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The goal of the Stroke Treatment Academic Industry Roundtable (STAIR) meetings is to advance the development of acute and restorative stroke therapies. Summary of Review- At the STAIR VII recommendations for strategies to maximize the use of intravenous thrombolytics through targeting public educ...

journal_title：Stroke

authors： Albers GW,Goldstein LB,Hess DC,Wechsler LR,Furie KL,Gorelick PB,Hurn P,Liebeskind DS,Nogueira RG,Saver JL,STAIR VII Consortium.

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acetazolamide is commonly used with single-photon CT to assess the cerebrovascular reserve in patients with internal carotid artery stenosis or occlusion. In this study we wanted to evaluate the effects of adenosine, a well-known vasodilatatory compound with a short biological half-life, on brain...

journal_title：Stroke

authors： Soricelli A,Postiglione A,Cuocolo A,De Chiara S,Ruocco A,Brunetti A,Salvatore M,Ell PJ

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Knowledge of cerebral blood volume (CBV) is invaluable in identifying the primary cause of brain swelling in patients with stroke or severe head injury, and it might also help in clinical decision making in patients thought to have hemodynamic transient ischemic attacks (TIAs). This investigation...

journal_title：Stroke

authors： Muizelaar JP,Fatouros PP,Schröder ML

更新日期：1997-10-01 00:00:00

abstract：:As part of a prospective study of mood disorders in stroke patients, interviews were obtained from 37 patients at 1 year and 48 patients at 2 years follow-up. In-hospital evaluations for these 65 follow-up patients found that 9 patients (14%) had symptom clusters of major depression, 12 patients (18%) had symptom clus...

journal_title：Stroke

authors： Robinson RG,Bolduc PL,Price TR

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The vitamin K-dependent protein Z (PZ) has been shown to possess anticoagulant as well as procoagulant properties. Plasma levels of PZ show a broad interindividual variation, but it is unknown to which extent this variation is under genetic control. Recent clinical studies revealed contradictory ...

journal_title：Stroke

authors： Lichy C,Kropp S,Dong-Si T,Genius J,Dolan T,Hampe T,Stoll F,Reuner K,Grond-Ginsbach C,Grau A

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke during pregnancy is an emerging concern. Although females undergo many physiological, endocrine, and neurological alterations during pregnancy, the consequences of such changes on outcome after stroke are unclear. It is predicted that increases in steroid hormones observed during pregnancy...

journal_title：Stroke

authors： Spencer SJ,Galic MA,Tsutsui M,Pittman QJ,Mouihate A

更新日期：2008-03-01 00:00:00

abstract：:Using in vivo brain microdialysis, we studied amino acid release in the striatum and cortex of eight rats following permanent middle cerebral artery occlusion. We then processed all brains for histopathologic assessment of the volume of ischemic damage 4 hours after occlusion. Ischemic damage was varied by occlusion o...

journal_title：Stroke

authors： Butcher SP,Bullock R,Graham DI,McCulloch J

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Kinesthesia, the sense of body motion, is essential to proper control and execution of movement. Despite its importance for activities of daily living, no current clinical measures can objectively measure kinesthetic deficits. The goal of this study was to use robotic technology to quantify preva...

journal_title：Stroke

authors： Semrau JA,Herter TM,Scott SH,Dukelow SP

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...

journal_title：Stroke

authors： Chen H,Hu CJ,He YY,Yang DI,Xu J,Hsu CY

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity, reflecting active, multifocal bleeding or a variable bleeding time course, would predict ICH growth. METHODS:Three raters examined baseline su...

journal_title：Stroke

authors： Barras CD,Tress BM,Christensen S,MacGregor L,Collins M,Desmond PM,Skolnick BE,Mayer SA,Broderick JP,Diringer MN,Steiner T,Davis SM,Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators.

更新日期：2009-04-01 00:00:00

abstract：:We report two patients with mixed transcortical aphasia following left frontal lobe infarctions. Although there was no evidence of anatomic isolation of the speech area on computed tomograms or magnetic resonance imaging scans, single-photon emission computed tomography in one case demonstrated diminished blood flow o...

journal_title：Stroke

authors： Rapcsak SZ,Krupp LB,Rubens AB,Reim J

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intake of fruits and vegetables has been related to lower risk of ischemic stroke, but nutrients responsible for this apparent benefit remain ill-defined. Tocopherols (vitamin E) have also been proposed to be protective. METHODS:We conducted a prospective, nested case-control analysis among male...

journal_title：Stroke

authors： Hak AE,Ma J,Powell CB,Campos H,Gaziano JM,Willett WC,Stampfer MJ

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Genetic factors involved in the pathogenesis of primary intracerebral hemorrhage (PICH) remain unknown. One of the candidate genes is SERPINA3. Results of a Spanish study suggested that TT genotype of the A/T SERPINA3 polymorphism in the signal peptide sequence was a risk factor for PICH in normo...

journal_title：Stroke

authors： Pera J,Slowik A,Dziedzic T,Szczudlik A

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Early neurological deterioration (END) occurs in ≥20% of single small subcortical infarctions (SSSIs; axial diameter ≤20 mm in the perforator territories) and deters functional recovery. Both microvasculopathies and atherosclerosis have been proposed to independently contribute to the occurrence ...

journal_title：Stroke

authors： Jeong HG,Kim BJ,Yang MH,Han MK,Bae HJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron overload has been associated with greater oxidative stress and brain injury in experimental cerebral ischemia and reperfusion. This study investigates whether high serum ferritin levels, as an index of increased cellular iron stores, are associated with poor outcome, hemorrhagic transformati...

journal_title：Stroke

authors： Millan M,Sobrino T,Castellanos M,Nombela F,Arenillas JF,Riva E,Cristobo I,García MM,Vivancos J,Serena J,Moro MA,Castillo J,Dávalos A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hyperglycemia may worsen brain injury during acute cerebral infarction. We tested the feasibility and tolerability of aggressive hyperglycemia correction with intravenous insulin compared with usual care during acute cerebral infarction. METHODS:We conducted a randomized, multicenter, blinded pi...

journal_title：Stroke

authors： Bruno A,Kent TA,Coull BM,Shankar RR,Saha C,Becker KJ,Kissela BM,Williams LS

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies on the hyperdense middle cerebral artery (MCA) sign were conducted using > or =5-mm thickness noncontrast-computed tomography (NCT). The purpose of this study was to compare thin-section NCT with 5-mm NCT in the detection of thrombus in acute ischemic stroke. METHODS:Enrolled we...

journal_title：Stroke

authors： Kim EY,Lee SK,Kim DJ,Suh SH,Kim J,Heo JH,Kim DI

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neutrophil Extracellular Traps (NETs) are DNA extracellular networks decorated with histones and granular proteins produced by activated neutrophils. NETs have been identified as major triggers and structural factors of thrombosis. A recent study designated extracellular DNA threads from NETs as ...

journal_title：Stroke

authors： Ducroux C,Di Meglio L,Loyau S,Delbosc S,Boisseau W,Deschildre C,Ben Maacha M,Blanc R,Redjem H,Ciccio G,Smajda S,Fahed R,Michel JB,Piotin M,Salomon L,Mazighi M,Ho-Tin-Noe B,Desilles JP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:ASCOD phenotyping (A, atherosclerosis; S, small vessel disease; C, cardiac pathology; O, other causes; and D, dissection) assigns a degree of likelihood to every potential cause (1 for potentially causal, 2 for causality is uncertain, 3 for unlikely causal but disease is present, 0 for absence of...

journal_title：Stroke

authors： Sirimarco G,Lavallée PC,Labreuche J,Meseguer E,Cabrejo L,Guidoux C,Klein IF,Olivot JM,Abboud H,Adraï V,Kusmierek J,Ratani S,Touboul PJ,Mazighi M,Steg PG,Amarenco P

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There have been relatively few community-based studies of long-term prognosis after acute stroke. This study aimed to provide precise estimates of the absolute and relative risks of dying in an unselected cohort of patients with a first-ever stroke. METHODS:Six hundred seventy-five patients were...

journal_title：Stroke

authors： Dennis MS,Burn JP,Sandercock PA,Bamford JM,Wade DT,Warlow CP

更新日期：1993-06-01 00:00:00

abstract：:Using a scintillation camera system, hemispheric and regional cerebral blood flow was measured repeatedly during the course after a stroke. In 20 patients who improved clinically mean hemispheric and regional flow and relative weight of rapidly perfused compartment increased, while these values decreased in 15 patient...

journal_title：Stroke

authors： Heiss WD,Zeiler K,Turnheim M,Podreka I

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The collagen alpha2(I) gene (COL1A2) on chromosome 7q22.1, a positional and functional candidate for intracranial aneurysm (IA), was extensively screened for susceptibility in Japanese IA patients. METHODS:Twenty-one single nucleotide polymorphisms (SNPs) of COL1A2 were genotyped in genomic DNA ...

journal_title：Stroke

authors： Yoneyama T,Kasuya H,Onda H,Akagawa H,Hashiguchi K,Nakajima T,Hori T,Inoue I

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We evaluated the impact of admission hyperglycemia (HG) on stroke outcome in relation to the timing of reperfusion in patients treated with tissue plasminogen activator (tPA). METHODS:We studied 138 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with...

journal_title：Stroke

authors： Alvarez-Sabín J,Molina CA,Ribó M,Arenillas JF,Montaner J,Huertas R,Santamarina E,Rubiera M

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several studies have reported on the correlation of ultrasonic carotid plaque morphology, cerebrovascular symptoms, and intraplaque hemorrhage. This study correlates ultrasonic carotid plaque morphology with the degree of carotid stenosis. METHODS:Carotid arteries (n=2460) were examined by using...

journal_title：Stroke

authors： AbuRahma AF,Wulu JT Jr,Crotty B

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Progression of asymptomatic carotid artery stenosis (ACAS) in patients with >50% luminal narrowing is considered a potential risk factor for ischemic stroke; however, subclinical molecular biomarkers of ACAS progression are lacking. Recent studies suggest a regulatory function for several microRN...

journal_title：Stroke

authors： Dolz S,Górriz D,Tembl JI,Sánchez D,Fortea G,Parkhutik V,Lago A

更新日期：2017-01-01 00:00:00