Influence of anesthetics on metabolic, functional and pathological responses to regional cerebral ischemia.

abstract：:Arteriolar diameters and venular erythrocyte velocities in the small pial vessels on the surface of the cat brain were measured by TV methods during induced epileptic seizures through a cranial window. Grand mal seizures maximally dilated arterioles and increased venular erythrocyte velocity up to 400%. High positive ...

journal_title：Stroke

authors： Myers RR,Intaglietta M

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transtemporal insonation in transcranial Doppler sonography is often impaired by an insufficient signal-to-noise ratio, especially in elderly patients. A transpulmonary stable air microbubble suspension was injected intravenously in humans as an intracranial ultrasonic contrast agent. METHODS:In...

journal_title：Stroke

authors： Ries F,Honisch C,Lambertz M,Schlief R

更新日期：1993-12-01 00:00:00

abstract：:Background and Purpose- This ARISTOPHANES study (Anticoagulants for Reduction in Stroke: Observational Pooled Analysis on Health Outcomes and Experience of Patients) used multiple data sources to compare stroke/systemic embolism (SE) and major bleeding (MB) among a large number of nonvalvular atrial fibrillation patie...

journal_title：Stroke

authors： Lip GYH,Keshishian A,Li X,Hamilton M,Masseria C,Gupta K,Luo X,Mardekian J,Friend K,Nadkarni A,Pan X,Baser O,Deitelzweig S

更新日期：2018-12-01 00:00:00

abstract：:Cerebral blood flow (CBF) was determined in the rat under 70% nitrous oxide anesthesia and pentobarbital anesthesia. The application of the Fick principle technique of Kety et al. was modified utilizing 133Xe infused intravenously steadily for 30 seconds, at which time the animal was decapitated and the head frozen in...

journal_title：Stroke

authors： Matsumoto A,Namon R,Utsunomiya Y,Kogure K,Scheinberg P,Reinmuth OM

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:If it could be determined whether cerebral blood flow can be maintained (autoregulated) during transient falls in arterial blood pressure, we might be able to identify patients with carotid stenosis who are at risk of stroke. However, conventional methods of determining autoregulation in such pat...

journal_title：Stroke

authors： White RP,Markus HS

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is increasing interest in defining stroke lesion volume thresholds to predict poststroke outcome. However, there is a paucity of data on factors that impact the association between critical infarct thresholds volume and outcome. We sought to determine whether lesion thresholds best predicti...

journal_title：Stroke

authors： Patti J,Helenius J,Puri AS,Henninger N

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to test whether arterial spin labeling (ASL) can detect significant differences in relative cerebral blood flow (rCBF) in the core, mismatch, and reverse-mismatch regions, and whether rCBF values measured by ASL in those areas differ from values obtained using dynamic su...

journal_title：Stroke

authors： Hernandez DA,Bokkers RP,Mirasol RV,Luby M,Henning EC,Merino JG,Warach S,Latour LL

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:20% of ischemic stroke is in the posterior circulation, but there is little prospective data on early recurrent stroke risk and whether vertebrobasilar stenosis predicts a high recurrence risk. This natural history data are important as it is technically possible to stent such lesions. Contrast e...

journal_title：Stroke

authors： Gulli G,Khan S,Markus HS

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients. METHODS:Logistic regression was used to evaluate baseline characteristics and recan...

journal_title：Stroke

authors： Linfante I,Walker GR,Castonguay AC,Dabus G,Starosciak AK,Yoo AJ,Abou-Chebl A,Britz GW,Marden FA,Alvarez A,Gupta R,Sun CH,Martin C,Holloway WE,Mueller-Kronast N,English JD,Malisch TW,Bozorgchami H,Xavier A,Rai AT,F

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vorapaxar is an antiplatelet agent that antagonizes thrombin-mediated activation of the protease-activated receptor-1 on platelets. We tested the efficacy and safety of vorapaxar in a prespecified analysis in the stroke subcohort from a multinational, randomized, placebo-controlled trial. METHOD...

journal_title：Stroke

authors： Morrow DA,Alberts MJ,Mohr JP,Ameriso SF,Bonaca MP,Goto S,Hankey GJ,Murphy SA,Scirica BM,Braunwald E,Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events–TIMI 50 Steering Committee and Investigators

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To clarify hemodynamic risk factors for hemorrhage in arteriovenous malformations (AVMs), the mean transit time (MTT) of feeding arteries and draining veins in AVMs with and without hemorrhage was measured and analyzed. METHODS:Morphological features such as the number and diameter of draining a...

journal_title：Stroke

authors： Todaka T,Hamada J,Kai Y,Morioka M,Ushio Y

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis for acute ischemic stroke is beneficial within 4.5 hours of symptom onset, but the effect rapidly decreases over time, necessitating quick diagnostic in-hospital work-up. Initial time strain occasionally results in treatment of patients with an alternate diagnosis (stroke...

journal_title：Stroke

authors： Zinkstok SM,Engelter ST,Gensicke H,Lyrer PA,Ringleb PA,Artto V,Putaala J,Haapaniemi E,Tatlisumak T,Chen Y,Leys D,Sarikaya H,Michel P,Odier C,Berrouschot J,Arnold M,Heldner MR,Zini A,Fioravanti V,Padjen V,Beslac-Bu

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Familial aggregation of intracranial aneurysms (IAs) indicates a genetic role in the pathogenesis of this disease. Despite a number of reported susceptibility loci, no disease-causing gene variants have been identified. In this study, we used a parametric genomewide linkage approach to search for...

journal_title：Stroke

authors： Santiago-Sim T,Depalma SR,Ju KL,McDonough B,Seidman CE,Seidman JG,Kim DH

更新日期：2009-03-01 00:00:00

abstract：:Utah mortality rates for cerebrovascular disease (ICD numbers 430--438) are 13% below U.S. rates. About 70% of Utahns are members of the Church of Jesus Christ of Latter-day Saints, commonly called Mormons of LDS, which proscribes use of tobacco and alcohol. Other studies on this group have found significantly lower o...

journal_title：Stroke

authors： Lyon JL,Bishop CT,Nielsen NS

更新日期：1981-09-01 00:00:00

abstract：:The relationship between central conduction time (CCT) and levels of regional blood flow were studied in 9 primates. Flows were recorded in both hemispheres using the method of hydrogen (2 min) clearance. The somatosensory evoked potentials were recorded over the contralateral cortex and the dorsal columns, following ...

journal_title：Stroke

authors： Hargadine JR,Branston NM,Symon L

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to assess the prevalence and characteristics of silent cerebral infarction in a population-based consecutive autopsy series of residents of Hisayama, Kyushu, Japan. METHODS:Autopsy records, cerebral pathological findings, and clinical charts of 966 Hisayama resident...

journal_title：Stroke

authors： Shinkawa A,Ueda K,Kiyohara Y,Kato I,Sueishi K,Tsuneyoshi M,Fujishima M

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerated brain atrophy is described following ischemic stroke, but it is not known whether atrophy rates vary over the poststroke period. Examining rates of brain atrophy allows the identification o...

journal_title：Stroke

authors： Brodtmann A,Khlif MS,Egorova N,Veldsman M,Bird LJ,Werden E

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolysis rates among minor stroke (MS) patients are increasing because of increased recognition of disability in this group and guideline changes regarding treatment indications. We examined the association of delays in door-to-needle (DTN) time with stroke severity. METHODS:We performed a r...

journal_title：Stroke

authors： Rostanski SK,Shahn Z,Elkind MSV,Liberman AL,Marshall RS,Stillman JI,Williams O,Willey JZ

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral blood flow after cardiac arrest is reduced during the delayed hypoperfusion phase, while cerebral metabolic rate of oxygen returns to baseline values. Hypocapnia can induce cerebral ischemia in neurosurgical patients who already have reduced cerebral blood flow. The purpose of the presen...

journal_title：Stroke

authors： Buunk G,van der Hoeven JG,Meinders AE

更新日期：1997-08-01 00:00:00

abstract：:Background and Purpose- Stroke is the most frequent severe clinical event in patients with Fabry disease. We aimed to evaluate the cerebral magnetic resonance imaging findings of patients with Fabry disease and assess their association with future stroke risk after enzyme replacement therapy (ERT) induction. Methods- ...

journal_title：Stroke

authors： Yagita Y,Sakai N,Miwa K,Ohara N,Tanaka M,Sakaguchi M,Kitagawa K,Mochizuki H

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The remaining limitations of ultrasonographic imaging in accurately quantifying internal carotid stenosis or diagnosing internal carotid occlusion may be overcome by enhancing the echogenicity of flowing arterial blood with contrast agents. This study assessed the usefulness of the intravenous (t...

journal_title：Stroke

authors： Sitzer M,Fürst G,Siebler M,Steinmetz H

更新日期：1994-02-01 00:00:00

abstract：:Background and Purpose- The importance of weight change for the risk of stroke is not well known. We examined the associations between early- and mid-life weight change and risks of stroke and death during long-term follow-up of healthy men. Methods- We recruited healthy men aged between 40 and 59 years and performed ...

journal_title：Stroke

authors： Prestgaard E,Mariampillai J,Engeseth K,Erikssen J,Bodegård J,Liestøl K,Kjeldsen S,Grundvold I,Berge E

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This study was conducted to analyze the association between reported risk factors for Alzheimer's disease, apolipoprotein E epsilon4 allele, and cardiovascular disease and neuropathological changes essential for the diagnosis of Alzheimer's disease. METHODS:Our data are based on clinical and pos...

journal_title：Stroke

authors： Irina A,Seppo H,Arto M,Paavo R Sr,Hilkka S

更新日期：1999-03-01 00:00:00

abstract：:Brief episodes of ischemia can protect against subsequent damaging ischemic events; however, the molecular mechanisms responsible for protection are poorly understood. Identifying genes involved in this process could provide insight into cell survival and treatment of stroke. We developed a murine model of ischemic pr...

journal_title：Stroke

authors： Stenzel-Poore MP,Stevens SL,Simon RP

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The natural history of stroke is worse in women than in men. Controversial data have been published on the efficacy of thrombolysis with recombinant tissue plasminogen activator (rtPA) according to gender. We evaluated gender differences in the efficacy and safety outcomes of intravenous rtPA usi...

journal_title：Stroke

authors： Meseguer E,Mazighi M,Labreuche J,Arnaiz C,Cabrejo L,Slaoui T,Guidoux C,Olivot JM,Abboud H,Lapergue B,Raphaeli G,Klein IF,Lavallée PC,Amarenco P

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Maternal cigarette smoking increases the risk of neonatal morbidity. We tested the hypothesis that perinatal nicotine exposure causes heightened brain vulnerability to hypoxic-ischemic (HI) injury in neonatal rats through aberrant expression patterns of angiotensin II type 1 (AT(1)R) and type 2 (...

journal_title：Stroke

authors： Li Y,Xiao D,Dasgupta C,Xiong F,Tong W,Yang S,Zhang L

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with carotid occlusive disease and stage 2 cerebral hemodynamic failure, characterized by an increased oxygen extraction fraction (OEF) as measured by positron emission tomography (PET) and otherwise known as misery perfusion, have a high risk of cerebral ischemia and subsequent stroke. ...

journal_title：Stroke

authors： Imaizumi M,Kitagawa K,Hashikawa K,Oku N,Teratani T,Takasawa M,Yoshikawa T,Rishu P,Ohtsuki T,Hori M,Matsumoto M,Nishimura T

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The migratory efficiency of mesenchymal stem cells (MSC) toward cerebral infarct after transplantation is limited. Valproate (VPA) and lithium enhance in vitro migration of MSC by upregulating CXC chemokine receptor 4 and matrix metalloproteinase-9, respectively. Ability of VPA and lithium to pro...

journal_title：Stroke

authors： Tsai LK,Wang Z,Munasinghe J,Leng Y,Leeds P,Chuang DM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Computed tomography (CT) is used to study coronary artery plaques, but little is known about its potential to characterize plaque composition. This study assesses the relation between carotid calcium score (CCS) by CT and plaque composition, namely extracellular matrix, inflammatory mediators, an...

journal_title：Stroke

authors： Edsfeldt A,Dias N,Elmståhl B,Müller MF,Berg K,Nitulescu M,Persson A,Ekberg O,Gonçalves I

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is important to know the costs of hospitalization for patients undergoing endovascular embolectomy so that comparisons can be made with payments to hospitals. METHODS:Using the National Inpatient Sample, we evaluated the costs of hospitalization for patients treated with endovascular embolect...

journal_title：Stroke

authors： Brinjikji W,Kallmes DF,Rabinstein AA,Lanzino G,Cloft HJ

更新日期：2011-11-01 00:00:00