Low carotid calcium score is associated with higher levels of glycosaminoglycans, tumor necrosis factor-alpha, and parathyroid hormone in human carotid plaques.

abstract：:We produced cerebral vasospasm in 29 dogs by the "two-hemorrhage" method of intracisternal injections, 2 days apart, of autogenous arterial blood. Leukotriene (LT) C4, LTD4, and LTE4 were purified from incubated basilar artery, medulla oblongata, hypothalamus, median eminence, and blood clot from around the basilar ar...

journal_title：Stroke

authors： Yokota M,Tani E,Maeda Y

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to describe the clinical and imaging features of patients with tumor-like presentation of primary angiitis of the central nervous system. METHODS:We retrospectively analyzed 10 patients enrolled in the French primary angiitis of the central nervous system cohort, who initially presented...

journal_title：Stroke

authors： de Boysson H,Boulouis G,Dequatre N,Godard S,Néel A,Arquizan C,Detante O,Bloch-Queyrat C,Zuber M,Touzé E,Bienvenu B,Aouba A,Guillevin L,Naggara O,Pagnoux C,French Vasculitis Study Group.

更新日期：2016-09-01 00:00:00

abstract：:The media cross-sectional area, the media thickness, the internal radius and the ratio between media thickness and internal radius were determined in consecutive sections of extraparenchymal cerebral arteries of 7- and 12-month-old normotensive and spontaneously hypertensive rats. The study included intracranial pial ...

journal_title：Stroke

authors： Nordborg C,Fredriksson K,Johansson BB

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Intravenous Nimodipine West European Stroke Trial (INWEST) found a correlation between nimodipine-induced reduction in blood pressure (BP) and an unfavorable outcome in acute stroke. We sought to confirm this correlation with and without adjustment for prognostic variables and to investigate ...

journal_title：Stroke

authors： Ahmed N,Näsman P,Wahlgren NG

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been suggested that the interleukin-1A (IL-1A) allele 2 is a risk factor for Alzheimer's disease (AD). Because cerebral amyloid angiopathy-related hemorrhage (CAAH) often coexists with AD, we examined the IL-1A polymorphism in CAAH. METHODS:In a case-control study, patients with pathologi...

journal_title：Stroke

authors： McCarron MO,Stewart J,McCarron P,Love S,Vinters HV,Ironside JW,Mann DM,Graham DI,Nicoll JA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of athersclerosis in the difference between the pathogenesis of large-vessel disease (LVD) and small-vessel disease (SVD) is a matter of debate. Common carotid artery intima-media thickness (CCA IMT) is a marker of atherosclerosis. Our aim was to compare CCA IMT between SVD and LVD patie...

journal_title：Stroke

authors： Pruissen DM,Gerritsen SA,Prinsen TJ,Dijk JM,Kappelle LJ,Algra A,SMART Study Group.

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Osteogenic protein-1 (OP1) not only possesses trophic activity on bone tissue but also influences neuronal survival and differentiation in vitro. Specific receptors for OP1 are present in brain and spinal cord and can be upregulated during cerebral contusion. OP1 is a member of the transforming g...

journal_title：Stroke

authors： Lin SZ,Hoffer BJ,Kaplan P,Wang Y

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We tested the hypothesis that intravenous administration of basic fibroblast growth factor (bFGF) during 4 hours of permanent focal ischemia would affect acute brain injury. METHODS:Halothane-anesthetized cats underwent left middle cerebral artery (MCA) occlusion for 4 hours. Control cats receiv...

journal_title：Stroke

authors： Bethel A,Kirsch JR,Koehler RC,Finklestein SP,Traystman RJ

更新日期：1997-03-01 00:00:00

abstract：:Background and Purpose- Enhancement of erythrophagocytosis by macrophages in a timely manner can limit the toxic effects of erythrocyte metabolites and promote brain recovery after intracerebral hemorrhage (ICH). In the current study, we investigated the therapeutic effect of retinoid X receptor agonist, bexarotene, i...

journal_title：Stroke

authors： Chang CF,Massey J,Osherov A,Angenendt da Costa LH,Sansing LH

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Policy makers require evidence on the costs and outcomes of different ways of organizing stroke care. This study compared the costs and survival of different ways of providing stroke care. METHODS:Hospitalized stroke patients from 13 European centers were included, with demographic, case-mix, an...

journal_title：Stroke

authors： Grieve R,Hutton J,Bhalla A,Rastenytë D,Ryglewicz D,Sarti C,Lamassa M,Giroud M,Dundas R,Wolfe CD

更新日期：2001-07-01 00:00:00

abstract：:The external diameters of rat and rabbit basilar arteries were determined before and after formaldehyde fixation in relaxed and drug constricted vessels. Fixation usually resulted in an immediate vessel constriction followed by partial relaxation after several hours. However, the results were inconstant from vessel to...

journal_title：Stroke

authors： Hart MN,O'Donnell SL

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Stroke patients are heterogeneous not only with respect to etiology but also in terms of preexisting clinical conditions. Approximately one fifth of patients with acute stroke are hyperglycemic and/or have had a recent infectious or inflammatory condition. Summary of Review-- Experimental research indicates ...

journal_title：Stroke

authors： Kent TA,Soukup VM,Fabian RH

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:This prospective study was aimed to evaluate the effects of surgical revascularization on cerebral oxygen metabolism in moyamoya disease. METHODS:This study included totally 69 hemispheres of 42 patients who underwent superficial temporal artery to middle cerebral artery anastomosis and indirect...

journal_title：Stroke

authors： Kuroda S,Kashiwazaki D,Hirata K,Shiga T,Houkin K,Tamaki N

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Iron is an essential element for the human body. It has, however, been suggested that excessive iron stores may increase the risk of vascular disease. So far, epidemiologic studies on stroke are sparse. METHODS:We studied the association between iron status and stroke risk in a population-based ...

journal_title：Stroke

authors： van der A DL,Grobbee DE,Roest M,Marx JJ,Voorbij HA,van der Schouw YT

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Priorities in the care of stroke patients are often intuitive. An open and translucent priority-setting procedure would benefit patients, professionals, and decision-makers. Prioritization is an innovative part of the new Swedish national stroke guidelines. METHODS:Working groups identified diag...

journal_title：Stroke

authors： Norrving B,Wester P,Sunnerhagen KS,Terént A,Sohlberg A,Berggren F,Wester PO,Asplund K,Stroke Guidelines Working Group, National Board of Health and Welfare, Stockholm, Sweden.

更新日期：2007-07-01 00:00:00

abstract：:I used leg and arm paresis to predict outcome measured as extremity function in a prospective study of 75 consecutive hemiplegic patients admitted to an inpatient stroke rehabilitation unit. In each patient, extremity paresis was quantified according to the five-point scoring system advised by the Medical Research Cou...

journal_title：Stroke

authors： Olsen TS

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Angiotensin II produces oxidative stress and endothelial dysfunction in cerebral arteries, and angiotensin II type I receptors may play a role in longevity and vascular aging. Angiotensin-converting enzyme type 2 (ACE2) converts angiotensin II to angiotensin (1-7) and thus, may protect against ef...

journal_title：Stroke

authors： Peña Silva RA,Chu Y,Miller JD,Mitchell IJ,Penninger JM,Faraci FM,Heistad DD

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic treatment of stroke carries the risk of hemorrhagic transformation. Therefore, the potential of MRI for prediction of recombinant tissue plasminogen activator (rtPA)-induced bleeding is explored to identify patients in whom rtPA treatment may provoke such complications. METHODS:Spon...

journal_title：Stroke

authors： Neumann-Haefelin C,Brinker G,Uhlenküken U,Pillekamp F,Hossmann KA,Hoehn M

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To investigate whether neuroimaging information has added predictive value compared with clinical information for independency in activities of daily living (ADL) 1 year after stroke. METHODS:Seventy-five first-ever middle cerebral artery stroke survivors were evaluated in logistic regression an...

journal_title：Stroke

authors： Schiemanck SK,Kwakkel G,Post MW,Kappelle LJ,Prevo AJ

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelin receptor antagonists such as clazosentan decrease large-artery vasospasm after experimental and clinical subarachnoid hemorrhage. We used clazosentan to gain insight into the pathophysiology of subarachnoid hemorrhage by determining if decreasing vasospasm is associated with alleviatio...

journal_title：Stroke

authors： Sabri M,Ai J,Macdonald RL

更新日期：2011-05-01 00:00:00

abstract：:Leukoaraiosis quantified by computerized densitometric measurements of reduced Hounsfield numbers was correlated with local cerebral blood flow on the same computed tomographic images of 35 patients with multi-infarct dementia and 16 age-matched elderly normal volunteers. The ratio for area of frontal leukoaraiosis to...

journal_title：Stroke

authors： Kawamura J,Meyer JS,Terayama Y,Weathers S

更新日期：1991-05-01 00:00:00

abstract：:Changes of regional cerebral blood flow from rest to mental activation by a visually presented spatial reasoning test were measured during normo- and hypercapnia in 10 healthy subjects. Hypercapnia, elicited by inhalation of 6% CO2, resulted in similar flow increases in all 32 cortical regions measured. Increases of f...

journal_title：Stroke

authors： Maximilian VA,Prohovnik I,Risberg J

更新日期：1980-07-01 00:00:00

abstract：:I provide the theoretical basis for an error calculus for measurements of cerebral blood flow using a freely diffusible tracer substance such as xenon-133. The use of the error calculus is exemplified by a study of the effect on the error margins in measurements of gray matter blood flow from flow level, relative weig...

journal_title：Stroke

authors： Ryding E

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis for acute ischemic stroke is usually based on clinical assessment, blood test results, and CT findings. Intravenous thrombolysis of stroke mimics may occur but has not been studied in detail. METHODS:We determined frequency, clinical characteristics, and outcome of mimic...

journal_title：Stroke

authors： Winkler DT,Fluri F,Fuhr P,Wetzel SG,Lyrer PA,Ruegg S,Engelter ST

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous research has reported worse outcomes after stroke for women and for African Americans, but few prospective population-based studies have systematically examined demographic differences on long-term stroke outcomes. Race and gender differences in 1-year stroke outcomes were examined using...

journal_title：Stroke

authors： Roth DL,Haley WE,Clay OJ,Perkins M,Grant JS,Rhodes JD,Wadley VG,Kissela B,Howard G

更新日期：2011-03-01 00:00:00

abstract：:The gap between existing knowledge and the patient care provided in stroke has become more apparent. The translational gap is evidence of our scientific progress, but the sheer magnitude of our implementation gap is astounding. For instance, almost 5 decades ago we recognized the risk factors for stroke, yet in Canada...

journal_title：Stroke

authors： Hakim AM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite a high incidence of poststroke dementia, there is no specific treatment for this condition. Because the evaluation of poststroke cognitive deficits in animal models of stroke is exceedingly challenging, the preclinical evaluation of candidate drugs is limited. We aimed to explore the impa...

journal_title：Stroke

authors： Diederich K,Schmidt A,Strecker JK,Schäbitz WR,Schilling M,Minnerup J

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sonic hedgehog (Shh) protein is required for the maintenance of neural progenitor cells (NPCs) in the embryonic and adult hippocampus. Brain ischemia causes increased proliferation of hippocampal NPCs. We therefore examined whether Shh regulates the increase in proliferation of NPCs after ischemi...

journal_title：Stroke

authors： Sims JR,Lee SW,Topalkara K,Qiu J,Xu J,Zhou Z,Moskowitz MA

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To assess the association of lesion location and risk of aspiration and to establish predictors of transient versus extended risk of aspiration after supratentorial ischemic stroke. METHODS:Atlas-based localization analysis was performed in consecutive patients with MRI-proven first-time acute s...

journal_title：Stroke

authors： Galovic M,Leisi N,Müller M,Weber J,Abela E,Kägi G,Weder B

更新日期：2013-10-01 00:00:00

abstract：:Cystatin C, a protein inhibitor of lysosomal cysteine proteinases, was demonstrated by immunohistochemical techniques to be present in the birefringent amyloid deposits of the small arteries in the cerebrum, cerebellum, and leptomeninges of 10 Icelandic individuals with hereditary cerebral hemorrhage with amyloidosis....

journal_title：Stroke

authors： Löfberg H,Grubb AO,Nilsson EK,Jensson O,Gudmundsson G,Blöndal H,Arnason A,Thorsteinsson L

更新日期：1987-03-01 00:00:00