The morphometry of consecutive segments in cerebral arteries of normotensive and spontaneously hypertensive rats.

Abstract:

:The media cross-sectional area, the media thickness, the internal radius and the ratio between media thickness and internal radius were determined in consecutive sections of extraparenchymal cerebral arteries of 7- and 12-month-old normotensive and spontaneously hypertensive rats. The study included intracranial pial and basal arteries as well as extracranial cervical arteries. In the chronically hypertensive rats the media to radius ratio was consistently higher than in normotensive rats over the entire calibre spectrum investigated (radius 5-400 micron). The increase of the ratio in the extracranial arteries of the hypertensive rats was exclusively due to a thicker media. In the basal intracranial arteries the increase of ratio was due to a thicker media and/or a smaller internal radius in 7- and 12-month-old rats with moderate hypertension (mean arterial pressure, MAP 171 +/- 8 and 177 +/- 7 mm Hg respectively). In 7-month-old rats with severe hypertension (MAP 204 +/- 11 mm Hg) the increase of ratio was mainly due to a smaller internal radius. The observed structural alterations are likely to be of hemodynamic importance.

journal_name

Stroke

journal_title

Stroke

authors

Nordborg C,Fredriksson K,Johansson BB

doi

10.1161/01.str.16.2.313

subject

Has Abstract

pub_date

1985-03-01 00:00:00

pages

313-20

issue

2

eissn

0039-2499

issn

1524-4628

journal_volume

16

pub_type

杂志文章

相关文献

STROKE文献大全
  • Silent cerebral infarction in a community-based autopsy series in Japan. The Hisayama Study.

    abstract:BACKGROUND AND PURPOSE:The purpose of this study was to assess the prevalence and characteristics of silent cerebral infarction in a population-based consecutive autopsy series of residents of Hisayama, Kyushu, Japan. METHODS:Autopsy records, cerebral pathological findings, and clinical charts of 966 Hisayama resident...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.26.3.380

    authors: Shinkawa A,Ueda K,Kiyohara Y,Kato I,Sueishi K,Tsuneyoshi M,Fujishima M

    更新日期:1995-03-01 00:00:00

  • Evidence of corticospinal tract injury at midbrain in patients with subarachnoid hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Clear elucidation of the exact pathophysiological mechanisms of motor weakness in patients with subarachnoid hemorrhage has not yet been achieved. We attempted to investigate injury to the corticospinal tract in patients with subarachnoid hemorrhage using diffusion tensor imaging. METHODS:Twenty...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.112.661116

    authors: Yeo SS,Choi BY,Chang CH,Kim SH,Jung YJ,Jang SH

    更新日期:2012-08-01 00:00:00

  • Plaque components in symptomatic moderately stenosed carotid arteries related to cerebral infarcts: the plaque at RISK study.

    abstract:BACKGROUND AND PURPOSE:Carotid plaque composition is a major determinant of cerebrovascular events. In the present analysis, we evaluated the relationship between intraplaque hemorrhage (IPH) and a thin/ruptured fibrous cap (TRFC) in moderately stenosed carotid arteries and cerebral infarcts on MRI in the ipsilateral h...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.114.008121

    authors: de Rotte AA,Truijman MT,van Dijk AC,Liem MI,Schreuder FH,van der Kolk AG,de Kruijk JR,Daemen MJ,van der Steen AF,de Borst GJ,Luijten PR,Nederkoorn PJ,Kooi ME,van der Lugt A,Hendrikse J

    更新日期:2015-02-01 00:00:00

  • Which time-to-peak threshold best identifies penumbral flow? A comparison of perfusion-weighted magnetic resonance imaging and positron emission tomography in acute ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:In acute ischemic stroke, the hypoperfused but viable tissue is the main therapeutic target. In clinical routine, time-to-peak (TTP) maps are frequently used to estimate the hemodynamic compromise and to calculate the mismatch volume. We evaluated the accuracy of TTP maps to identify penumbral fl...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000147043.29399.f6

    authors: Sobesky J,Zaro Weber O,Lehnhardt FG,Hesselmann V,Thiel A,Dohmen C,Jacobs A,Neveling M,Heiss WD

    更新日期:2004-12-01 00:00:00

  • Combining theta burst stimulation with training after subcortical stroke.

    abstract:BACKGROUND AND PURPOSE:Repetitive transcranial magnetic stimulation of the primary motor cortex (M1) may improve outcomes after stroke. The aim of this study was to determine the effects of M1 theta burst stimulation (TBS) and standardized motor training on upper-limb function of patients with chronic stroke. METHODS:...

    journal_title:Stroke

    pub_type: 信件

    doi:10.1161/STROKEAHA.110.583278

    authors: Ackerley SJ,Stinear CM,Barber PA,Byblow WD

    更新日期:2010-07-01 00:00:00

  • Self-reported depression and use of antidepressants after stroke: a national survey.

    abstract:BACKGROUND AND PURPOSE:Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. MATERIALS AND METHODS:In the Swedish national quality assessment register, Riks-Stroke, 15 747 stroke sur...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000121643.86762.9a

    authors: Eriksson M,Asplund K,Glader EL,Norrving B,Stegmayr B,Terént A,Asberg KH,Wester PO,Riks-Stroke Collaboration.

    更新日期:2004-04-01 00:00:00

  • Increased lipid peroxidation in vulnerable brain regions after transient forebrain ischemia in rats.

    abstract::We examined cerebral lipid peroxidation, estimated by a thiobarbituric acid test, in rat brain regions after 30 minutes of severe forebrain ischemia and at recirculation periods of up to 72 hours. The lipid peroxide levels remained unaltered in all brain regions during ischemia and during the first hour of recirculati...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.20.7.918

    authors: Bromont C,Marie C,Bralet J

    更新日期:1989-07-01 00:00:00

  • Measurement of regional brain glucose utilization in vivo using [2(-14)C] glucose.

    abstract::A new technique is described for the autoradiographic determination of regional brain glucose metabolism employing 14C labeled glucose as substrate and measurement principles previously described for whole brain. Regional glucose values correlate closely with those reported for the 14C-deoxyglucose technique. The meth...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.10.6.690

    authors: Hawkins R,Hass WK,Ransohoff J

    更新日期:1979-11-01 00:00:00

  • Morbidity After Symptomatic Hemorrhage of Cerebral Cavernous Malformation: A Nomogram Approach to Risk Assessment.

    abstract:BACKGROUND AND PURPOSE:Symptomatic hemorrhage contributes to an increased risk of repeated bleeding and morbidity in cerebral cavernous malformation (CCM). A better understanding of morbidity after CCM hemorrhage would be helpful to identify patients of higher risk for unfavorable outcome and tailor individualized mana...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.120.029942

    authors: Ma L,Zhang S,Li Z,Wu CX,Wang Z,Zhan L,Hao Q,Wang H,Ye X,Chen X,Liu YO,Wang S,Zhao YL

    更新日期:2020-10-01 00:00:00

  • A systematic review of the risks of stroke and death due to endarterectomy for symptomatic carotid stenosis.

    abstract:BACKGROUND AND PURPOSE:Carotid endarterectomy reduces the risk of carotid territory ischemic stroke ipsilateral to a recently symptomatic severe carotid stenosis. However, the benefit is limited by the risks of stroke and death associated with the operation. Although reported surgical risks vary enormously, there has b...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.str.27.2.260

    authors: Rothwell PM,Slattery J,Warlow CP

    更新日期:1996-02-01 00:00:00

  • Cerebrovascular disease in Utah, 1968--1971.

    abstract::Utah mortality rates for cerebrovascular disease (ICD numbers 430--438) are 13% below U.S. rates. About 70% of Utahns are members of the Church of Jesus Christ of Latter-day Saints, commonly called Mormons of LDS, which proscribes use of tobacco and alcohol. Other studies on this group have found significantly lower o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.12.5.564

    authors: Lyon JL,Bishop CT,Nielsen NS

    更新日期:1981-09-01 00:00:00

  • Do statins improve outcomes and reduce the incidence of vasospasm after aneurysmal subarachnoid hemorrhage: a meta-analysis.

    abstract:BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) is a relatively rare cause of stroke with a high rate of morbidity and mortality, primarily due to the occurrence of delayed vasospasm. To date, many therapies have been proposed to help prevent vasospasm, but very few have been proven effective. The initiation of st...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析

    doi:10.1161/STROKEAHA.107.508341

    authors: Sillberg VA,Wells GA,Perry JJ

    更新日期:2008-09-01 00:00:00

  • Accuracy of transcranial Doppler compared with CT angiography in diagnosing arterial obstructions in acute ischemic strokes.

    abstract:BACKGROUND AND PURPOSE:Patients with acute ischemic stroke and intracranial arterial obstructions have a poor prognosis and a high probability of deteriorating at 24 hours. We aimed to evaluate the diagnostic accuracy of power motion mode Doppler (PMD-TCD) compared with CT angiography as standard in diagnosing intracra...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.108.542704

    authors: Brunser AM,Lavados PM,Hoppe A,Lopez J,Valenzuela M,Rivas R

    更新日期:2009-06-01 00:00:00

  • Patient selection for carotid endarterectomy: how far is risk modeling applicable to the individual?

    abstract:BACKGROUND AND PURPOSE:Risk-factor modeling has been proposed to identify patients with carotid stenosis who will most benefit from surgery. Validation by independent institutions performing carotid endarterectomy is necessary to determine the applicability of such models to the individual patient. METHODS:A series of...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/01.str.0000051729.79990.fb

    authors: Barth A,Bassetti C

    更新日期:2003-02-01 00:00:00

  • Computerized detection of cerebral emboli and discrimination from artifact using Doppler ultrasound.

    abstract:BACKGROUND AND PURPOSE:Transcranial Doppler ultrasound can detect circulating cerebral emboli. Monitoring of patients with potential embolic sources may allow identification of high-risk patients who can then be selected for prophylactic treatment. However, practical patient monitoring will require automated programs t...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.11.1667

    authors: Markus H,Loh A,Brown MM

    更新日期:1993-11-01 00:00:00

  • Lipohyalinosis and miliary microaneurysms causing cerebral hemorrhage in a patient with moyamoya. A clinicopathological study.

    abstract::Moyamoya is an intriguing and controversial syndrome. This patient study serves to align the pathophysiology of intracranial hemorrhage in moyamoya with the cerebral vascular disease seen with hypertension, or aging. The historical evidence linking lipohyalinosis and microaneurysms to cerebral hemorrhage is reviewed, ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.11.4.405

    authors: Mauro AJ,Johnson ES,Chikos PM,Alvord EC Jr

    更新日期:1980-07-01 00:00:00

  • Mixed transcortical aphasia without anatomic isolation of the speech area.

    abstract::We report two patients with mixed transcortical aphasia following left frontal lobe infarctions. Although there was no evidence of anatomic isolation of the speech area on computed tomograms or magnetic resonance imaging scans, single-photon emission computed tomography in one case demonstrated diminished blood flow o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.21.6.953

    authors: Rapcsak SZ,Krupp LB,Rubens AB,Reim J

    更新日期:1990-06-01 00:00:00

  • Predictors of major vascular events in patients with a transient ischemic attack or minor ischemic stroke and with nonrheumatic atrial fibrillation. European Atrial Fibrillation Trial (EAFT) Study Group.

    abstract:BACKGROUND AND PURPOSE:The risk of major vascular events after an initial episode of cerebral ischemia in patients with nonrheumatic atrial fibrillation (NRAF) varies from 2% to 15% in the first year and is approximately 5% yearly thereafter. Few studies have reported on risk factors that can be used to identify high-r...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1161/01.str.26.5.801

    authors: van Latum JC,Koudstaal PJ,Venables GS,van Gijn J,Kappelle LJ,Algra A

    更新日期:1995-05-01 00:00:00

  • Increases in cerebral atherosclerosis according to CHADS2 scores in patients with stroke with nonvalvular atrial fibrillation.

    abstract:BACKGROUND AND PURPOSE:The CHADS(2) score is used for risk stratification of ischemic stroke in patients with nonvalvular atrial fibrillation and high CHADS(2) scores are associated with increased risk of stroke. Most components of the CHADS(2) score are also risk factors for atherosclerosis. Therefore, high CHADS(2) s...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.602987

    authors: Kim YD,Cha MJ,Kim J,Lee DH,Lee HS,Nam CM,Nam HS,Heo JH

    更新日期:2011-04-01 00:00:00

  • Role of platelet function in symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage.

    abstract::To evaluate the role of platelet function in the pathogenesis of cerebral vasospasm, we compared sequential changes of platelet aggregability and beta-thromboglobulin and thromboxane B2 concentrations in blood samples from the internal jugular and peripheral vein of 13 patients with aneurysmal subarachnoid hemorrhage....

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.22.7.854

    authors: Ohkuma H,Suzuki S,Kimura M,Sobata E

    更新日期:1991-07-01 00:00:00

  • Preischemic but not postischemic zinc protoporphyrin treatment reduces infarct size and edema accumulation after temporary focal cerebral ischemia in rats.

    abstract:BACKGROUND AND PURPOSE:Zinc protoporphyrin (ZnPP) has multiple actions. It is an interleukin-1 antagonist as well as a hemeoxygenase inhibitor. Interleukin-1 is produced in ischemic brain and probably contributes to ischemic injury, although the role of heme oxygenase during ischemia is unknown. Whether ZnPP treatment ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.26.6.1035

    authors: Kadoya C,Domino EF,Yang GY,Stern JD,Betz AL

    更新日期:1995-06-01 00:00:00

  • Neglect is more common and severe at extreme hemoglobin levels in right hemispheric stroke.

    abstract:BACKGROUND AND PURPOSE:Anemia is 1 potential mechanism by which the brain receives inadequate oxygenation. The purpose of this study was to determine in acute stroke patients whether lower hemoglobin values were associated with worse hemispatial neglect. METHODS:In 203 subjects, neglect testing batteries were administ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.585265

    authors: Gottesman RF,Bahrainwala Z,Wityk RJ,Hillis AE

    更新日期:2010-08-01 00:00:00

  • Late measures of brain injury after neonatal hypoxia-ischemia in mice.

    abstract:BACKGROUND AND PURPOSE:This work was undertaken to determine to what degree long-term neurofunctional outcome of neonatal hypoxic-ischemic (HI) brain injury in mice correlates with anatomical extent of cerebral damage assessed by magnetic resonance imaging (MRI) and histopathology. METHODS:On postnatal day 7, mice wer...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000137768.25203.df

    authors: Ten VS,Wu EX,Tang H,Bradley-Moore M,Fedarau MV,Ratner VI,Stark RI,Gingrich JA,Pinsky DJ

    更新日期:2004-09-01 00:00:00

  • Telemedicine Cognitive Behavioral Therapy for Anxiety After Stroke: Proof-of-Concept Randomized Controlled Trial.

    abstract:BACKGROUND AND PURPOSE:Disabling anxiety affects a quarter of stroke survivors but access to treatment is poor. We developed a telemedicine model for delivering guided self-help cognitive behavioral therapy (CBT) for anxiety after stroke (TASK-CBT). We aimed to evaluate the feasibility of TASK-CBT in a randomized contr...

    journal_title:Stroke

    pub_type: 杂志文章,随机对照试验

    doi:10.1161/STROKEAHA.120.029042

    authors: Chun HY,Carson AJ,Tsanas A,Dennis MS,Mead GE,Calabria C,Whiteley WN

    更新日期:2020-08-01 00:00:00

  • Postischemic (1 hour) hypothermia significantly reduces ischemic cell damage in rats subjected to 2 hours of middle cerebral artery occlusion.

    abstract:BACKGROUND AND PURPOSE:We investigated the effect of hypothermia induced 1 hour after transient (2-hour) middle cerebral artery occlusion on the extent of ischemic cell damage in the rat. METHODS:Middle cerebral artery occlusion was induced extracranially by insertion of a nylon filament into the right internal caroti...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.8.1235

    authors: Zhang RL,Chopp M,Chen H,Garcia JH,Zhang ZG

    更新日期:1993-08-01 00:00:00

  • Stroke rehabilitation outcome. A potential use of predictive variables to establish levels of care.

    abstract:BACKGROUND AND PURPOSE:The most powerful predictors of functional recovery and eventual home discharge among stroke survivors are the initial severity of the stroke and the patient's age. We analyzed a large population of stroke rehabilitation admissions by stratifying subgroups with coherent outcomes in an attempt to ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.1.128

    authors: Alexander MP

    更新日期:1994-01-01 00:00:00

  • Normal-Appearing White Matter Integrity Is a Predictor of Outcome After Ischemic Stroke.

    abstract::Background and Purpose- The aim of the present study was to evaluate the relationship between normal-appearing white matter (NAWM) integrity and postischemic stroke recovery in 4 main domains including cognition, mood, gait, and dependency. Methods- A prospective study was conducted, including patients diagnosed for a...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.026886

    authors: Sagnier S,Catheline G,Dilharreguy B,Linck PA,Coupé P,Munsch F,Bigourdan A,Debruxelles S,Poli M,Olindo S,Renou P,Rouanet F,Dousset V,Berthoz S,Tourdias T,Sibon I

    更新日期:2020-02-01 00:00:00

  • Analysis of mean transit time of contrast medium in ruptured and unruptured arteriovenous malformations: a digital subtraction angiographic study.

    abstract:BACKGROUND AND PURPOSE:To clarify hemodynamic risk factors for hemorrhage in arteriovenous malformations (AVMs), the mean transit time (MTT) of feeding arteries and draining veins in AVMs with and without hemorrhage was measured and analyzed. METHODS:Morphological features such as the number and diameter of draining a...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/01.STR.0000089924.43363.E3

    authors: Todaka T,Hamada J,Kai Y,Morioka M,Ushio Y

    更新日期:2003-10-01 00:00:00

  • Black-white differences in stroke risk among young adults.

    abstract:BACKGROUND AND PURPOSE:Little information is available regarding black-white differences in stroke incidence in young adults. METHODS:Cerebral infarction and intracerebral hemorrhage rates among adults 15 to 44 years of age were studied in Baltimore City and Baltimore County for 1988. Diagnoses were based on neurologi...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:

    authors: Kittner SJ,McCarter RJ,Sherwin RW,Sloan MA,Stern BJ,Johnson CJ,Buchholz D,Seipp MJ,Price TR

    更新日期:1993-12-01 00:00:00

  • Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study.

    abstract:BACKGROUND AND PURPOSE:The role of uric acid as a risk factor for myocardial infarction is controversial, and little is known about its role as a risk factor for stroke. Recent evidence suggests that uric acid may be an important causal agent in cardiovascular disease, for example, by inducing renal disease and hence h...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000221716.55088.d4

    authors: Bos MJ,Koudstaal PJ,Hofman A,Witteman JC,Breteler MM

    更新日期:2006-06-01 00:00:00