Do statins improve outcomes and reduce the incidence of vasospasm after aneurysmal subarachnoid hemorrhage: a meta-analysis.

abstract：BACKGROUND AND PURPOSE:Inflammatory and immune mechanisms can precipitate cerebrovascular thrombosis and hemorrhage. Immunologic tolerance can be induced to a specific antigen by intranasal instillation of that antigen. Lymphocytes tolerized in this way provide local immunosuppression on restimulation with the same ant...

journal_title：Stroke

authors： Takeda H,Spatz M,Ruetzler C,McCarron R,Becker K,Hallenbeck J

更新日期：2002-09-01 00:00:00

abstract：:We examined the 21-aminosteroid U74006F, a potent inhibitor of lipid peroxidation, for potential neuroprotective effects in a canine model of complete cerebral ischemia. Two 1.5-mg/kg boluses were administered to six dogs, the first bolus 15 minutes prior to a 12-minute episode of complete cerebral ischemia and the se...

journal_title：Stroke

authors： Perkins WJ,Milde LN,Milde JH,Michenfelder JD

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ultrasonographic plaque echolucency has been studied as a stroke risk marker in carotid atherosclerotic disease. We performed a systematic review and meta-analysis to summarize the association between ultrasound-determined carotid plaque echolucency and future ipsilateral stroke risk. METHODS:We...

journal_title：Stroke

authors： Gupta A,Kesavabhotla K,Baradaran H,Kamel H,Pandya A,Giambrone AE,Wright D,Pain KJ,Mtui EE,Suri JS,Sanelli PC,Mushlin AI

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have previously shown that 17beta-estradiol reduces infarction volume in female rats. The present study determined whether single injection or chronic implantation of estrogen confers neuroprotection in male animals with middle cerebral artery occlusion (MCAO) and whether there is an interacti...

journal_title：Stroke

authors： Toung TJ,Traystman RJ,Hurn PD

更新日期：1998-08-01 00:00:00

abstract：:We have evaluated carotid gamma imaging using 111Indium-labelled platelets in the diagnosis of carotid artery disease and measured the accumulation of labelled platelets on endarterectomy specimens. Autologous 111In labelled platelets were injected in 25 patients with TIA. Gamma images were then taken daily and indepe...

journal_title：Stroke

authors： Goldman M,Leung JO,Aukland A,Hawker RJ,Drolc Z,McCollum CN

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The management of carotid atherosclerosis is well-established for symptomatic stenosis above 69%, but the optimal approach for managing lower degrees of narrowing remains uncertain. Because the risk of stroke increases with higher grades of stenosis, we are inclined to consider low-grade disease ...

journal_title：Stroke

authors： Wasserman BA,Wityk RJ,Trout HH 3rd,Virmani R

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelial progenitor cells (EPCs) migrate from bone marrow to systemic circulation in response to tissue ischemia where they differentiate into mature endothelial cells for angiogenesis in situ. This study tested the hypothesis that the level of circulating EPCs is substantially increased and p...

journal_title：Stroke

authors： Yip HK,Chang LT,Chang WN,Lu CH,Liou CW,Lan MY,Liu JS,Youssef AA,Chang HW

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke MRI protocols provide useful information about underlying vessel pathologies in the anterior circulation by means of intracranial time-of-flight angiography. However, these protocols mostly fail in the posterior circulation to differentiate between congenital variants and secondary thrombo...

journal_title：Stroke

authors： Freund W,Kassubek J,Aschoff AJ,Huber R

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is scant population-based information on incidence and risk factors for ischemic stroke subtypes. METHODS:We identified all 454 residents of Rochester, Minn, with a first ischemic stroke between 1985 and 1989 from the Rochester Epidemiology Project medical records linkage system. We used S...

journal_title：Stroke

authors： Petty GW,Brown RD Jr,Whisnant JP,Sicks JD,O'Fallon WM,Wiebers DO

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia can lead to pneumonia and subsequent death after acute stroke. However, no prospective study has demonstrated reduced pneumonia prevalence after implementation of a dysphagia screen. METHODS:We performed a single-center prospective interrupted time series trial of a quality initiative ...

journal_title：Stroke

authors： Titsworth WL,Abram J,Fullerton A,Hester J,Guin P,Waters MF,Mocco J

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We analyzed the impact of detailed anatomic characteristics on the results of endovascular coil embolization for anterior communicating artery (AcoA) aneurysms and developed a predictive model estimating the probability of successful endovascular treatment. METHODS:One hundred eighty-one AcoA an...

journal_title：Stroke

authors： Gonzalez N,Sedrak M,Martin N,Vinuela F

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Combined Lysis of Thrombus in Brain Ischemia With Transcranial Ultrasound and Systemic T-PA-Hands-Free (CLOTBUST-HF) study is a first-in-human, National Institutes of Health-sponsored, multicenter, open-label, pilot safety trial of tissue-type plasminogen activator (tPA) plus a novel operator...

journal_title：Stroke

authors： Barreto AD,Alexandrov AV,Shen L,Sisson A,Bursaw AW,Sahota P,Peng H,Ardjomand-Hessabi M,Pandurengan R,Rahbar MH,Barlinn K,Indupuru H,Gonzales NR,Savitz SI,Grotta JC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) and carotid duplex (CD) provide rapid and safe screening for stroke patients but are highly operator dependent. We explored the feasibility of telemedicine (TM)-guided TCD/CD administered by a health care provider inexperienced with ultrasound. METHODS:Dual video scree...

journal_title：Stroke

authors： Mikulik R,Alexandrov AV,Ribo M,Garami Z,Porche NA,Fulep E,Grotta JC,Wojner-Alexandrov AW,Choi JY

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Watershed ischemia is a significant cause of stroke in severe carotid disease, but its pathophysiology is unsettled. Although hemodynamic compromise has long been regarded as the main mechanism-particularly with deep watershed infarction-there is some contradictory evidence from clinical and path...

journal_title：Stroke

authors： Moustafa RR,Izquierdo-Garcia D,Jones PS,Graves MJ,Fryer TD,Gillard JH,Warburton EA,Baron JC

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A ruptured intracranial aneurysm (IA) is the leading cause of a subarachnoid hemorrhage. This study seeks to define a specific gene whose mutation leads to disease. METHODS:More than 500 IA probands and 100 affected families were enrolled and clinically characterized. Whole exome sequencing was ...

journal_title：Stroke

authors： Santiago-Sim T,Fang X,Hennessy ML,Nalbach SV,DePalma SR,Lee MS,Greenway SC,McDonough B,Hergenroeder GW,Patek KJ,Colosimo SM,Qualmann KJ,Hagan JP,Milewicz DM,MacRae CA,Dymecki SM,Seidman CE,Seidman JG,Kim DH

更新日期：2016-12-01 00:00:00

abstract：:Background and Purpose- Hyperacute assessment and management of patients with stroke, termed code stroke, is a time-sensitive and high-stakes clinical scenario. In the context of the current coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 virus, the ability to deliver timely and efficacious care ...

journal_title：Stroke

authors： Khosravani H,Rajendram P,Notario L,Chapman MG,Menon BK

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A locus containing the elastin gene has been linked to familial intracranial aneurysms in 2 distinct populations. We investigated the association of single-nucleotide polymorphisms (SNPs) and haplotypes of SNPs in the elastin gene with the occurrence of subarachnoid hemorrhage (SAH) from sporadic...

journal_title：Stroke

authors： Ruigrok YM,Seitz U,Wolterink S,Rinkel GJ,Wijmenga C,Urbán Z

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Abnormalities of dermal connective tissue have been detected in patients with spontaneous cervical artery dissections (sCAD), suggesting an underlying structural defect of the arterial wall. Alpha1-antitrypsin (A1-AT) is a circulating serine proteinase inhibitor of proteolytic enzymes that helps ...

journal_title：Stroke

authors： Vila N,Millán M,Ferrer X,Riutort N,Escudero D

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary arteriopathy, which mainly involves the brain causing stroke and dementia. Mice expressing the mutated protein display early dysfunction in vasoreactivity in resistance arteries, b...

journal_title：Stroke

authors： Stenborg A,Kalimo H,Viitanen M,Terent A,Lind L

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is not known what fraction of patients with symptomatic cerebral aneurysms are misdiagnosed at initial medical presentation. It is also not clear whether misdiagnosed patients more frequently deteriorate before definitive aneurysm diagnosis and therapy or achieve a poorer outcome than correctl...

journal_title：Stroke

authors： Mayer PL,Awad IA,Todor R,Harbaugh K,Varnavas G,Lansen TA,Dickey P,Harbaugh R,Hopkins LN

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Rates of development of de novo intracranial aneurysms and of growth of untreated additional aneurysms are largely unknown. We performed MRA in a large patient cohort with coiled aneurysms at 5-year follow-up. METHODS:In 276 patients with coiled intracranial aneurysms and 5±0.5 years of follow-u...

journal_title：Stroke

authors： Ferns SP,Sprengers ME,van Rooij WJ,van den Berg R,Velthuis BK,de Kort GA,Sluzewski M,van Zwam WH,Rinkel GJ,Majoie CB

更新日期：2011-02-01 00:00:00

abstract：:Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...

journal_title：Stroke

authors： Herold S,Frackowiak RS,Neil-Dwyer G

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with stroke and transient ischemic attack (TIA) often have comparable comorbidities, but it is unclear whether they have similar rates of depression or antidepressant use. METHODS:This study was a secondary analysis of a prospective cohort registry that enrolled subjects from 2006 to 20...

journal_title：Stroke

authors： El Husseini N,Goldstein LB,Peterson ED,Zhao X,Pan W,Olson DM,Zimmer LO,Williams JW Jr,Bushnell C,Laskowitz DT

更新日期：2012-06-01 00:00:00

abstract：:This study, in biologically bred hyperglycemic diabetic rats, examined the effect of a intravenous insulin infusion (1.5 units.hr-1) on blood, plasma, and brain glucose concentrations to determine their relationship during decreasing blood and plasma glucose levels. The data were compared to saline-treated diabetic ra...

journal_title：Stroke

authors： Hofer RE,Lanier WL

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:With the advent of time-dependent thrombolytic therapy for ischemic stroke, it has become increasingly important for stroke patients to arrive at the hospital quickly. This study investigates the association between the use of emergency medical services (EMS) and delay time among individuals with...

journal_title：Stroke

authors： Schroeder EB,Rosamond WD,Morris DL,Evenson KR,Hinn AR

更新日期：2000-11-01 00:00:00

abstract：PURPOSE:The aim of the present study was to investigate the diagnostic potential of contrast-enhanced transcranial color-coded real-time sonography (CE-TCCS) in otherwise ultrasound-refractory acute stroke patients with an ischemia in the territory of the middle cerebral artery (MCA). Furthermore, correlations of CE-TC...

journal_title：Stroke

authors： Postert T,Braun B,Meves S,Köster O,Przuntek H,Weber S,Büttner T

更新日期：1999-09-01 00:00:00

abstract：:It has been recognized that small intracerebral hemorrhage not uncommonly produced lacunar syndromes. In this study, we examined cases of intracerebral hemorrhage presenting as lacunar syndromes. Of 174 cases with recent intracerebral hemorrhage, 19 presented with a lacunar syndrome: 4 presented with pure motor hemipa...

journal_title：Stroke

authors： Mori E,Tabuchi M,Yamadori A

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some strokes of unknown etiology may be the result of a paradoxical embolism traversing through a nonfused foramen ovale (patent foramen ovale [PFO]). The utility of percutaneously placed devices for treatment of patients with cryptogenic stroke or transient ischemic attack (TIA) and PFO is unkno...

journal_title：Stroke

authors： Furlan AJ,Reisman M,Massaro J,Mauri L,Adams H,Albers GW,Felberg R,Herrmann H,Kar S,Landzberg M,Raizner A,Wechsler L,CLOSURE I Investigators.

更新日期：2010-12-01 00:00:00

abstract：:The literature on carotid surgery for lesions appropriate to prior episodes of ischemia has been reviewed. Only one randomized study and six non-controlled reports give useful data (this despite more than thirty years of surgical activity in this field). When analyzed by the IMPS (intact months of patient survival) cr...

journal_title：Stroke

authors： Jonas S

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Futile recanalization after acute ischemic stroke occurs in almost half of the patients despite optimal angiographic results. Multimodal neuroimaging may help to improve patient's selection but is still dismissed by many interventionalists. Our aim was to evaluate the accuracy of each parameter o...

journal_title：Stroke

authors： Espinosa de Rueda M,Parrilla G,Manzano-Fernández S,García-Villalba B,Zamarro J,Hernández-Fernández F,Sánchez-Vizcaino C,Carreón E,Morales A,Moreno A

更新日期：2015-09-01 00:00:00