Determinants of use of emergency medical services in a population with stroke symptoms: the Second Delay in Accessing Stroke Healthcare (DASH II) Study.

abstract：:A 25-year-old black man with sarcoidosis presented with transient ischemic attacks followed by sudden, persistent right hemiparesis. He gave a history of recent, recurrent lower motor neuron facial palsy. Computed tomography demonstrated an infarct in the left internal capsule. Chest x-ray film showed bilateral hilar ...

journal_title：Stroke

authors： Brown MM,Thompson AJ,Wedzicha JA,Swash M

更新日期：1989-03-01 00:00:00

abstract：:There have been numerous failures in the field of acute stroke therapy over many years, but the first large clinical trial showing preliminary indications of efficacy and safety of a neuroprotective drug, NXY-059, has now been fully reported. If confirmed, it will mean that a second therapy for acute stroke has been i...

journal_title：Stroke

authors： Zivin JA

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recanalization status after intravenous thrombolysis (IVT) in patients with ischemic stroke is a reference point to proceed with a rescue reperfusion intervention, although early neurological improvement (NI) may preclude endovascular procedures. We aimed to evaluate the importance of restoration...

journal_title：Stroke

authors： Kharitonova TV,Melo TP,Andersen G,Egido JA,Castillo J,Wahlgren N,SITS investigators.

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous studies on the hyperdense middle cerebral artery (MCA) sign were conducted using > or =5-mm thickness noncontrast-computed tomography (NCT). The purpose of this study was to compare thin-section NCT with 5-mm NCT in the detection of thrombus in acute ischemic stroke. METHODS:Enrolled we...

journal_title：Stroke

authors： Kim EY,Lee SK,Kim DJ,Suh SH,Kim J,Heo JH,Kim DI

更新日期：2005-12-01 00:00:00

abstract：:Five patients with nonseptic cerebral embolism of cardiac origin are reported in whom early anticoagulant therapy resulted in clinical deterioration or death from frank hemorrhage into the acute infarct. In each patient an initial CT scan excluded the presence of intracerebral hemorrhage and a second CT scan, after cl...

journal_title：Stroke

authors： Shields RW Jr,Laureno R,Lachman T,Victor M

更新日期：1984-05-01 00:00:00

abstract：:The protective properties of PY 108-068 against ischemic disturbances in the brain were investigated in vitro and in vivo. The calcium antagonistic effects were demonstrated on isolated, calcium-loaded arterial rings of feline cerebral arteries. Determination of brain tissue oxygenation with pO2 microelectrodes showed...

journal_title：Stroke

authors： Wiernsperger N,Gygax P,Hofmann A

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Quality of life (QoL) is important to stroke survivors yet is often recorded as a secondary measure in acute stroke randomized controlled trials. We examined whether commonly used stroke outcome measures captured aspects of QoL. METHODS:We examined primary outcomes by National Institutes of Heal...

journal_title：Stroke

authors： Ali M,Fulton R,Quinn T,Brady M,VISTA Collaboration.

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The composition of carotid atherosclerosis was visualized by using 3D MRI at high resolution with 200-micrometer (3) voxels. Magnetic resonance signal characteristics were correlated with plaque components, including collagenous cap, necrotic core, and calcification, to define resolution and othe...

journal_title：Stroke

authors： Coombs BD,Rapp JH,Ursell PC,Reilly LM,Saloner D

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Magnetic resonance perfusion (MRP) and computed tomographic perfusion (CTP) are being increasingly applied in acute stroke trials and clinical practice, yet the comparability of their perfusion values is not well validated. The aim of this study was to validate the comparability of CTP and MRP me...

journal_title：Stroke

authors： Lin L,Bivard A,Levi CR,Parsons MW

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autonomic dysfunction, including increased sympathetic drive and blunted baroreflex, has repeatedly been observed in acute stroke. Of clinical importance is that the stroke-related autonomic imbalance seems to be linked to worse outcome after stroke. Here, we discuss the role of baroreflex impair...

journal_title：Stroke

authors： Sykora M,Diedler J,Turcani P,Hacke W,Steiner T

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There are significant variations in mortality rates from stroke in Europe. A European Union BIOMED Concerted Action was established to assess and determine the reasons for the variations in case fatality and disability after stroke. METHODS:Hospital-based stroke registers were established in 12 ...

journal_title：Stroke

authors： Wolfe CD,Tilling K,Beech R,Rudd AG

更新日期：1999-02-01 00:00:00

abstract：:Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...

journal_title：Stroke

authors： White RP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The management of carotid atherosclerosis is well-established for symptomatic stenosis above 69%, but the optimal approach for managing lower degrees of narrowing remains uncertain. Because the risk of stroke increases with higher grades of stenosis, we are inclined to consider low-grade disease ...

journal_title：Stroke

authors： Wasserman BA,Wityk RJ,Trout HH 3rd,Virmani R

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Waist circumference has been shown to be a better predictor of cardiovascular risk than body mass index (BMI). Our case-control study aimed to evaluate the contribution of obesity and abdominal fat mass to the risk of stroke and transient ischemic attacks (TIA). METHODS:We recruited 1137 partici...

journal_title：Stroke

authors： Winter Y,Rohrmann S,Linseisen J,Lanczik O,Ringleb PA,Hebebrand J,Back T

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:MRI has become increasingly used in the acute setting to manage patients with stroke. There has been concern that MRI may not be sensitive in the detection of acute intracranial hemorrhage. We assessed whether strongly susceptibility-weighted MRI would be sensitive to intraparenchymal hemorrhage in the first...

journal_title：Stroke

authors： Patel MR,Edelman RR,Warach S

更新日期：1996-12-01 00:00:00

abstract：:We measured cerebrovascular reactivity to carbon dioxide in the cerebral cortex and the subcortical white matter of 12 healthy adult volunteers (four young subjects aged 21-24, four middle-aged subjects aged 34-40, and four elderly subjects aged 62-85 years). Blood flow was computed from the concentration history of x...

journal_title：Stroke

authors： Reich T,Rusinek H

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Close relations between leukoaraiosis detected by computed tomography or magnetic resonance imaging and stroke, particularly lacunar infarction, have been reported. We studied whether leukoaraiosis is related to long-term prognosis for patients with lacunar infarction. METHODS:We examined monthl...

journal_title：Stroke

authors： Miyao S,Takano A,Teramoto J,Takahashi A

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The significance of structural changes associated with cerebral small-vessel disease (SVD), including white matter lesions (WML), lacunes, and brain atrophy, to outcome from acute intracerebral hemorrhage is uncertain. We determined associations of computed tomographic radiological manifestations...

journal_title：Stroke

authors： Sato S,Delcourt C,Heeley E,Arima H,Zhang S,Al-Shahi Salman R,Stapf C,Woo D,Flaherty ML,Vagal A,Levi C,Davies L,Wang J,Robinson T,Lavados PM,Lindley RI,Chalmers J,Anderson CS,INTERACT2 Investigators.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We systematically compared and appraised contemporary guidelines on management of asymptomatic and symptomatic carotid artery stenosis. METHODS:We systematically searched for guideline recommendations on carotid endarterectomy (CEA) or carotid angioplasty/stenting (CAS) published in any language...

journal_title：Stroke

authors： Abbott AL,Paraskevas KI,Kakkos SK,Golledge J,Eckstein HH,Diaz-Sandoval LJ,Cao L,Fu Q,Wijeratne T,Leung TW,Montero-Baker M,Lee BC,Pircher S,Bosch M,Dennekamp M,Ringleb P

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine the effect of intracisternal administration of an endothelin-A receptor antagonist (BQ-123) against vasospasm in a monkey model and to determine whether this drug would have adverse interactions with intracisternal tissue plasminogen activator (TPA). METHODS:Thirty-three mo...

journal_title：Stroke

authors： Kim CJ,Bassiouny M,Macdonald RL,Weir B,Johns LM

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our goal was to compare outcomes of patients with proximal middle cerebral artery occlusions treated with intravenous tissue plasminogen activator (tPA) with those of patients treated with stent-based thrombectomy (SBT). METHODS:Patients with proximal middle cerebral artery occlusions included i...

journal_title：Stroke

authors： Leker RR,Eichel R,Gomori JM,Ramirez de Noriega F,Ben-Hur T,Cohen JE

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Stroke is the third leading cause of death and the leading cause of long-term disability in the United States. Although a host of genetic, biochemical, physiological, anatomic, and histological factors have been implicated, to varying degrees, in the pathogenesis of stroke, biophysical factors are believed t...

journal_title：Stroke

authors： Hademenos GJ,Massoud TF

更新日期：1997-10-01 00:00:00

abstract：:Nonvalvular atrial fibrillation (NVAF) can be a source of cardiogenic brain embolism. We retrospectively reviewed the clinical features of 56 patients with acute brain infarction and NVAF. Based on clinical criteria, 35 infarcts (63%) were classified as probably embolic, 13 infarcts (23%) as probably nonembolic and 8 ...

journal_title：Stroke

authors： Hart RG,Coull BM,Hart D

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite its low efficacy, aspirin is the most widely used drug for secondary stroke prevention. The reasons why stroke recurs while patients are on aspirin are unknown. We have analyzed a series of patients who had recurrent strokes while on aspirin. METHODS:Out of 2231 consecutive patients who ...

journal_title：Stroke

authors： Bornstein NM,Karepov VG,Aronovich BD,Gorbulev AY,Treves TA,Korczyn AD

更新日期：1994-02-01 00:00:00

abstract：:Background and Purpose- Low ankle-brachial index (ABI) identifies a stroke subgroup with high risk of recurrent stroke, cardiovascular events, and death. However, limited data exist on the relationship between low ABI and stroke in low and middle-income countries. Therefore, we evaluated the prevalence of ABI ≤0.90 (w...

journal_title：Stroke

authors： Abboud H,Monteiro Tavares L,Labreuche J,Arauz A,Bryer A,Lavados PM,Massaro A,Munoz Collazos M,Steg PG,Yamout BI,Vicaut E,Amarenco P

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:[123I]Iomazenil is a specific radioligand for the central benzodiazepine receptor that may be useful as an indicator of the intactness of cortical neurons after focal cerebral ischemia. We evaluated the binding of this receptor in reperfused cortex among patients with ischemic stroke to detect vi...

journal_title：Stroke

authors： Nakagawara J,Sperling B,Lassen NA

更新日期：1997-01-01 00:00:00

abstract：:Brain energy state and glycolytic metabolites were measured in young (6 month) and aged (28 month) male rats under normoxic (70% nitrous oxide, 30% oxygen) or hypoxic (PaO2 = 25 mm Hg) test conditions. Hypoxic ischemia was induced in one cerebral hemisphere by ligation of one carotid artery. Under normoxic test condit...

journal_title：Stroke

authors： Hoffman WE,Pelligrino D,Miletich DJ,Albrecht RF

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) is a devastating disease without a proven therapy to improve long-term outcome. Considerable controversy about the role of surgery remains. Minimally invasive endoscopic surgery for ICH offers the potential of improved neurological outcome. METHODS:We tested the hy...

journal_title：Stroke

authors： Vespa P,Hanley D,Betz J,Hoffer A,Engh J,Carter R,Nakaji P,Ogilvy C,Jallo J,Selman W,Bistran-Hall A,Lane K,McBee N,Saver J,Thompson RE,Martin N,ICES Investigators.

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Development of translational functional imaging modalities for atherosclerosis risk stratification is sought for stroke prediction. Our group has developed late-phase contrast-enhanced ultrasound (LP-CEUS) to quantify microbubble contrast retention within carotid atherosclerosis and shown it to s...

journal_title：Stroke

authors： Shalhoub J,Monaco C,Owen DR,Gauthier T,Thapar A,Leen EL,Davies AH

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients. METHODS:Logistic regression was used to evaluate baseline characteristics and recan...

journal_title：Stroke

authors： Linfante I,Walker GR,Castonguay AC,Dabus G,Starosciak AK,Yoo AJ,Abou-Chebl A,Britz GW,Marden FA,Alvarez A,Gupta R,Sun CH,Martin C,Holloway WE,Mueller-Kronast N,English JD,Malisch TW,Bozorgchami H,Xavier A,Rai AT,F

更新日期：2015-08-01 00:00:00