Brain metabolic changes in young vs aged rats during hypoxia.

abstract：BACKGROUND AND PURPOSE:Mechanisms of initiation, progression and rupture of cerebral aneurysms have not yet been fully understood despite its clinical significance. Matrix metalloproteinases (MMPs) are a family of proteinases which are involved in the remodeling of vascular walls. In the present study, we investigated ...

journal_title：Stroke

authors： Aoki T,Kataoka H,Morimoto M,Nozaki K,Hashimoto N

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine if ischemia involving Broca area predicts Broca aphasia more reliably in acute or chronic stroke. METHODS:We included consecutive right-hand-dominant patients with left hemisphere ischemic stroke (<48 hours from onset for acute stroke or >6 months after stroke for chronic s...

journal_title：Stroke

authors： Ochfeld E,Newhart M,Molitoris J,Leigh R,Cloutman L,Davis C,Crinion J,Hillis AE

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is inconclusive evidence of the effectiveness of psychological interventions for depression after stroke. We report the results from a randomized controlled trial of cognitive behavioral therapy (CBT). METHODS:Stroke patients admitted to hospital were invited to complete mood questionnaire...

journal_title：Stroke

authors： Lincoln NB,Flannaghan T

更新日期：2003-01-01 00:00:00

abstract：:Occlusion of the anterior cerebral artery is a rare condition. A review of CT scans from 413 patients with ischemic infarction confirmed this low relative incidence: only 3% of CT scans evidencing infarction involved the territory of the anterior cerebral artery. Four major mechanisms of anterior cerebral artery occlu...

journal_title：Stroke

authors： Gacs G,Fox AJ,Barnett HJ,Vinuela F

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The *2 allele of the aldehyde dehydrogenase 2 gene (ALDH2) is the most common variant in Asian populations. The variant resulting in enzyme dysfunction was highly related to coronary artery disease. Recently, genome-wide association studies also discovered that the 12q24 locus near ALDH2 gene was...

journal_title：Stroke

authors： Sung YF,Lu CC,Lee JT,Hung YJ,Hu CJ,Jeng JS,Chiou HY,Peng GS

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thromboxane prostaglandin receptors have been implicated to be involved in the atherosclerotic process. We assessed whether Terutroban, a thromboxane prostaglandin receptor antagonist, affects the progression of atherosclerosis, as measured by common carotid intima-media thickness and carotid pla...

journal_title：Stroke

authors： Bots ML,Ford I,Lloyd SM,Laurent S,Touboul PJ,Hennerici MG,Prevention of Cerebrovascular and Cardiovascular Events of Ischemic Origin With Terutroban in Patients With a History of Ischemic Stroke or Transient Ischemic Attack Vascular Ultrasou

更新日期：2014-08-01 00:00:00

abstract：:Results from 1,039 combined cervical and transcranial Doppler examinations are reported. Satisfactory transcranial signals were not found in 2.7% of the cases. Compared with angiography, the accuracy of transcranial criteria in assessing collateral flow over the circle of Willis was 94 and 88% for anterior and posteri...

journal_title：Stroke

authors： Grolimund P,Seiler RW,Aaslid R,Huber P,Zurbruegg H

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of the study is to compare the reliability of the Barthel activities of daily living score, which assesses disability, with the Rankin scale, which assesses handicap, and to determine their mutual agreement. METHODS:Fifty patients with stroke of varying severity were identified by a ...

journal_title：Stroke

authors： Wolfe CD,Taub NA,Woodrow EJ,Burney PG

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We examined patient demographic and hospital characteristics and clinical predictors of delay time from hospital arrival until CT among 20 374 patients enrolled in the North Carolina Collaborative Stroke Registry (January 2005 to April 2008). METHODS:Delay time was log-transformed in linear regr...

journal_title：Stroke

authors： Rose KM,Rosamond WD,Huston SL,Murphy CV,Tegeler CH

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A right-to-left shunt can be identified by contrast transcranial Doppler ultrasonography (c-TCD) at rest and/or after a Valsalva maneuver (VM) or by arterial blood gas (ABG) measurement. We assessed the influence of controlled strain pressures and durations during VM on the right-to-left passage ...

journal_title：Stroke

authors： Devuyst G,Piechowski-Józwiak B,Karapanayiotides T,Fitting JW,Kémeny V,Hirt L,Urbano LA,Arnold P,van Melle G,Despland PA,Bogousslavsky J

更新日期：2004-04-01 00:00:00

abstract：:Background and Purpose- Patients with intracerebral hemorrhage (ICH) and atrial fibrillation (AF) are at risk for ischemic events. While risk calculators (CHA2DS2-VASc and HAS-BLED) have been validated to assess risk for ischemic stroke and major bleeding in AF patients, decisions about anticoagulation must consider t...

journal_title：Stroke

authors： Stanton RJ,Eckman MH,Woo D,Moomaw CJ,Haverbusch M,Flaherty ML,Kleindorfer DO

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Early carotid surgery or stenting after thrombolytic treatment for stroke has become more common during recent years. It is unclear whether this carries an increased risk of postoperative complications and death. The aim of this nationwide population-based study was, therefore, to investigate the...

journal_title：Stroke

authors： Koraen-Smith L,Troëng T,Björck M,Kragsterman B,Wahlgren CM,Swedish Vascular Registry and the Riks-Stroke Collaboration.

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The limited walking ability that follows a stroke restricts the patient's independent mobility about the home and community, a significant social handicap. To improve the in-hospital prediction of functional outcome, the relationships between impairment, disability, and handicap were assessed wit...

journal_title：Stroke

authors： Perry J,Garrett M,Gronley JK,Mulroy SJ

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previously, we have shown that hyperthermia significantly increased neuronal damage after ischemic injury in a focal embolic model of stroke in rats. In the present study, we examined the effects of hyperthermia on the efficacy of thrombolytic therapy in this stroke model. METHODS:In part A, eff...

journal_title：Stroke

authors： Noor R,Wang CX,Shuaib A

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Loss of movement coordination is the main postacute symptom after cerebellar infarction. Although the course of motor recovery has been described previously, detailed kinematic descriptions of acute stage ataxia are rare and no attempt has been made to link improvements in motor function to measu...

journal_title：Stroke

authors： Konczak J,Pierscianek D,Hirsiger S,Bultmann U,Schoch B,Gizewski ER,Timmann D,Maschke M,Frings M

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We have developed a minimally invasive model of photothrombotic occlusion of the distal middle cerebral artery in rats and have evaluated the patterns and features of the resulting histopathologic injury in two normotensive strains. METHODS:Food-deprived male Sprague-Dawley (n = 14) and Wistar (...

journal_title：Stroke

authors： Markgraf CG,Kraydieh S,Prado R,Watson BD,Dietrich WD,Ginsberg MD

更新日期：1993-02-01 00:00:00

abstract：:The effect of respiration on the cerebrovascular response to elevated intracranial pressure (ICP) was studied in anesthetized dogs. Total and regional cerebral blood flows were measured using labelled microspheres. In spontaneously breathing dogs total and regional cerebral blood flows increased when cerebral perfusio...

journal_title：Stroke

authors： Malik AB,Krasney JA,Royce GJ

更新日期：1977-03-01 00:00:00

abstract：:Experimental regional cerebral ischemia was produced in the middle cerebral artery (MCA) territory in primates (M. mulatta) by macrosphere embolization. Determinations of percentage tissue dry weight and tissue sodium and potassium concentrations were obtained in samples from the ischemic and non-ischemic hemispheres ...

journal_title：Stroke

authors： Bremer AM,Yamada K,West CR

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The trends in stroke incidence reported so far have not been entirely consistent, although declining trends in mortality from stroke have been reported from a number of studies around the world. This study aims to evaluate the 10-year trends (from 1983 through 1992) in incidence, attack rate, and...

journal_title：Stroke

authors： Tuomilehto J,Rastenyte D,Sivenius J,Sarti C,Immonen-Räihä P,Kaarsalo E,Kuulasmaa K,Narva EV,Salomaa V,Salmi K,Torppa J

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The goal of this study was to determine whether release of endothelium-derived relaxing factor (EDRF) from carotid artery in response to acetylcholine is altered by aging. METHODS:Responses were examined in arteries from Wistar rats 6 to 8 months old (young rats), 24 to 26 months old (old rats),...

journal_title：Stroke

authors： Paternò R,Faraci FM,Heistad DD

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To increase the reliability of 99mTc-hexamethyl propyleneamine oxime (HMPAO) single photon emission computed tomography (SPECT) study in the evaluation of hemodynamic change with balloon test occlusion (BTO) of the internal carotid artery, we attempted to clarify the usefulness of additional moni...

journal_title：Stroke

authors： Kaminogo M,Ochi M,Onizuka M,Takahata H,Shibata S

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Central autonomic dysfunction increases stroke morbidity and mortality. We aimed to investigate whether poststroke autonomic dysfunction graded by Ewing battery can predict clinical outcome. METHODS:In this prospective observational study, we assessed autonomic function of ischemic stroke patien...

journal_title：Stroke

authors： Xiong L,Tian G,Leung H,Soo YOY,Chen X,Ip VHL,Mok VCT,Chu WCW,Wong KS,Leung TWH

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:In 15% to 20% of patients with a spontaneous subarachnoid hemorrhage, no aneurysm is found on the first angiogram. This review emphasizes that this group of patients is in fact heterogeneous and describes the clinical features, pattern of hemorrhage on early computed tomographic (CT) scan, prognosis, and pro...

journal_title：Stroke

authors： Rinkel GJ,van Gijn J,Wijdicks EF

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Ischemic brain injury secondary to an arterial occlusion is characterized by acute local inflammation. Blood polymorphonuclear leukocytes (PMNL), primarily neutrophils, adhere to endothelial cells and rapidly invade the injured brain after the arterial occlusion. This neutrophilic invasion might ...

journal_title：Stroke

authors： Kostulas N,Kivisäkk P,Huang Y,Matusevicius D,Kostulas V,Link H

更新日期：1998-02-01 00:00:00

abstract：:We measured cerebrovascular reactivity to carbon dioxide in the cerebral cortex and the subcortical white matter of 12 healthy adult volunteers (four young subjects aged 21-24, four middle-aged subjects aged 34-40, and four elderly subjects aged 62-85 years). Blood flow was computed from the concentration history of x...

journal_title：Stroke

authors： Reich T,Rusinek H

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:A number of clinical syndromes describing the presentation of deep brain infarcts are called lacunar syndromes resulting from small vessel occlusion (SVO). To verify the reliability of the clinical diagnosis "lacunar syndrome," the value was investigated with diffusion-weighted MRI (DWI). METHODS AND RESULT...

journal_title：Stroke

authors： Wessels T,Röttger C,Jauss M,Kaps M,Traupe H,Stolz E

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent evidence suggests a possible role for leukocytes in ischemic brain injury. This study examined the effect of activation of endogenous circulating leukocytes on cerebral blood flow in normal and neutrophil-depleted rats. METHODS:Leukocytes were activated by rapid injection of either 50 mic...

journal_title：Stroke

authors： Uhl MW,Kochanek PM,Schiding JK,Nemoto EM

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about how regions vary in their use of thrombolysis (intravenous tissue-type plasminogen activator and intra-arterial treatment) for acute stroke. We sought to determine regional variation in thrombolysis treatment and investigate the extent to which regional variation is accounte...

journal_title：Stroke

authors： Skolarus LE,Meurer WJ,Shanmugasundaram K,Adelman EE,Scott PA,Burke JF

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The significance of structural changes associated with cerebral small-vessel disease (SVD), including white matter lesions (WML), lacunes, and brain atrophy, to outcome from acute intracerebral hemorrhage is uncertain. We determined associations of computed tomographic radiological manifestations...

journal_title：Stroke

authors： Sato S,Delcourt C,Heeley E,Arima H,Zhang S,Al-Shahi Salman R,Stapf C,Woo D,Flaherty ML,Vagal A,Levi C,Davies L,Wang J,Robinson T,Lavados PM,Lindley RI,Chalmers J,Anderson CS,INTERACT2 Investigators.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The integrin-linked kinase (ILK) signaling pathway contributes to regulation of cellular adhesion, migration, and differentiation, and to apoptotic cell death after a variety of cell death stimuli. We have reported that overexpression of copper/zinc superoxide dismutase (SOD1) reduces apoptotic c...

journal_title：Stroke

authors： Saito A,Hayashi T,Okuno S,Nishi T,Chan PH

更新日期：2004-11-01 00:00:00