Abstract:
:Nonvalvular atrial fibrillation (NVAF) can be a source of cardiogenic brain embolism. We retrospectively reviewed the clinical features of 56 patients with acute brain infarction and NVAF. Based on clinical criteria, 35 infarcts (63%) were classified as probably embolic, 13 infarcts (23%) as probably nonembolic and 8 infarcts (14%) as of indeterminate pathogenesis. Among the 35 patients with presumed embolic infarcts, 12 patients were immediately anticoagulated without hemorrhagic complications. Of 23 patients who did not receive immediate anticoagulation, three (13%) experienced recurrent embolism (one each to brain, kidney and leg) within 10 days of initial embolism. There were no early recurrent emboli in patients receiving immediate anticoagulation or patients in the nonembolic or indeterminate category. Five additional patients experienced probable brain or systemic emboli within the 11 days prior to the marker stroke event. Including these patients, 20% (8 of 40) of all NVAF patients who were not immediately anticoagulated experienced recurrent embolism within 11 days of the initial embolus. Early recurrent emboli are common in NVAF patients who experience embolic stroke.
journal_name
Strokejournal_title
Strokeauthors
Hart RG,Coull BM,Hart Ddoi
10.1161/01.str.14.5.688subject
Has Abstractpub_date
1983-09-01 00:00:00pages
688-93issue
5eissn
0039-2499issn
1524-4628journal_volume
14pub_type
杂志文章相关文献
STROKE文献大全abstract::The double subarachnoid hemorrhage canine model was used to test the prophylactic value of immunosuppression in the prevention of cerebral vasospasm after subarachnoid hemorrhage. Dogs treated with cyclosporine A following the regimen prescribed for organ transplant procedures in patients showed a significant reductio...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.21.1.133
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Carotid angioplasty and stenting (CAS) has a higher incidence of periprocedural stroke compared with endarterectomy. Identifying CAS steps with the highest likelihood of embolization may have important implications. We evaluated CAS safety by correlating the findings of procedural transcranial Do...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.000659
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Disabling anxiety affects a quarter of stroke survivors but access to treatment is poor. We developed a telemedicine model for delivering guided self-help cognitive behavioral therapy (CBT) for anxiety after stroke (TASK-CBT). We aimed to evaluate the feasibility of TASK-CBT in a randomized contr...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.120.029042
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The antiplatelet agent sarpogrelate is a selective inhibitor of 5-hydroxytryptamine receptors. The purpose of this study was to compare the efficacy and safety of sarpogrelate with those of aspirin in Japanese ischemic stroke patients. METHODS:In total, 1510 patients with recent cerebral infarct...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.107.505131
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Carotid artery stenting (CAS) is an alternative to carotid endarterectomy (CEA) for stroke prevention. The value of this therapy relative to CEA remains uncertain. METHODS:In 10 958 Medicare patients aged 66 years or older between 2004 and 2006, we analyzed in-hospital, 1-year stroke, myocardial...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.608992
更新日期:2011-07-01 00:00:00
abstract::Background and Purpose- Intracerebral hemorrhage (ICH) has a poorer prognosis than acute ischemic stroke (AIS). However, clinician perception of prognosis may influence treatment decisions and adversely affect outcome. On acute CT, the conspicuity of ICH compared with AIS may lead clinicians to overestimate severity a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.022606
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Increased knowledge of stroke risk factors in the general population may lead to improved prevention of stroke. The objective of the present study was to assess knowledge of stroke risk factors and to determine factors associated with knowledge. METHODS:In a population-based survey, we sent a qu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000209332.96513.82
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this study was to validate the diagnosis of self-reported stroke. METHODS:During 1994-1995, 27 159 people attended a population health survey in the community of Tromso, Norway, a response rate of 77%. A total of 418 attenders reported a history of stroke. In 1997, all individuals wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.31.7.1602
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Magnetic resonance perfusion (MRP) and computed tomographic perfusion (CTP) are being increasingly applied in acute stroke trials and clinical practice, yet the comparability of their perfusion values is not well validated. The aim of this study was to validate the comparability of CTP and MRP me...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.114.005419
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is controversy about the optimal patient position for the detection of right-to-left shunt (RLS). The study was performed to investigate which patient position best detects RLS during contrast-enhanced transcranial Doppler. METHODS:We prospectively evaluated consecutive patients with ische...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.609875
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:This work was undertaken to determine to what degree long-term neurofunctional outcome of neonatal hypoxic-ischemic (HI) brain injury in mice correlates with anatomical extent of cerebral damage assessed by magnetic resonance imaging (MRI) and histopathology. METHODS:On postnatal day 7, mice wer...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000137768.25203.df
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Microvascular basal lamina damage occurs after cerebral ischemia and is important for the development of hemorrhage. The aim of this study was to determine whether hypothermia could maintain microvascular integrity in ischemic stroke. METHODS:Using the suture model, we subjected 12 rats to 3 hou...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000116866.60794.21
更新日期:2004-03-01 00:00:00
abstract::The postischemic production of PGE2, PGD2, 6-keto-PGF1 alpha, and TXB2 in brain tissue was studied in Mongolian gerbils using tissue extraction as well as a new ex vivo method. This new method permits the study of prostaglandin synthesis in slices from discrete areas of the brain (cortex, hippocampus, striatum, hypoth...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.1.111
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Watershed ischemia is a significant cause of stroke in severe carotid disease, but its pathophysiology is unsettled. Although hemodynamic compromise has long been regarded as the main mechanism-particularly with deep watershed infarction-there is some contradictory evidence from clinical and path...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.110.580415
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Ischemic injury triggers multiple pathological responses in the brain tissue, including spreading depolarizations across the cerebral cortex (cortical spreading depolarizations [CSD]). Microglia have been recently shown to play a significant role in the propagation of CSD. However, the intracellu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.032766
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We sought to evaluate the efficacy of testing the laryngeal cough reflex in identifying pneumonia risk in acute stroke patients. METHODS:We performed a prospective study of 400 consecutive acute stroke patients examined using the reflex cough test (RCT) compared with 204 consecutive acute stroke...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.30.6.1203
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.108.542308
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:It is unclear whether blood lipid profiles and statin use before intracerebral hemorrhage (ICH) are associated with its outcome. METHODS:The Helsinki ICH Study, a single-center observational registry of consecutive ICH patients, was used to study the associations between premorbid statin use, ba...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.001829
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several prospective studies have shown significant associations between plasma fibrinogen, viscosity, C-reactive protein (CRP), fibrin D-dimer, or tissue plasminogen activator (tPA) antigen and the risk of primary cardiovascular events. Little has been published on the associations of these varia...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/01.STR.0000181754.38408.4c
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There have been relatively few community-based studies of long-term prognosis after acute stroke. This study aimed to provide precise estimates of the absolute and relative risks of dying in an unselected cohort of patients with a first-ever stroke. METHODS:Six hundred seventy-five patients were...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.24.6.796
更新日期:1993-06-01 00:00:00
abstract:PURPOSE:To investigate differences between symptomatic and asymptomatic retinal embolism regarding the frequency and source of cerebral microemboli. METHODS:Thirty-seven patients with transient monocular blindness or retinal infarction and 27 patients (29 eyes) with asymptomatic retinal embolism were prospectively enr...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000125009.05353.7c
更新日期:2004-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Elevated leukocyte count has been associated with cardiovascular and cerebrovascular disease in several epidemiological studies. We sought to determine whether white blood cell count (WBC) is associated with carotid plaque thickness in a stroke-free, multiethnic cohort. METHODS:For this cross-se...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.32.4.842
更新日期:2001-04-01 00:00:00
abstract::A standardized neurologic assessment scoring instrument was developed and tested for use in a multicenter trial of hypervolemic hemodilution in acute hemispheric stroke. Components of the neurologic examination pertinent to hemispheric stroke syndromes were emphasized. The scale was evaluated using 16 acute stroke pat...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.18.3.665
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:White matter hyperintensities (WMH) are frequently seen on neuroimaging of elderly and are associated with cognitive decline and the development of dementia. Yet, the temporal dynamics of conversion of normal-appearing white matter (NAWM) into WMH remains unknown. We examined whether and when pro...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.118.020980
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Sleep-disordered breathing (SDB) represents a risk factor for cardiovascular morbidity after a cerebral ischemic event (acute ischemic event, ischemic stroke, or transient ischemic attack). In the present study, endothelial function and arterial stiffness were analyzed in patients who experienced...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/STROKEAHA.111.000112
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Tetrahydrobiopterin (THBP) is an essential cofactor for nitric oxide synthase (NOS), which is responsible for the synthesis of the endothelium-derived relaxing factor (EDRF) responsible for mediating the vasorelaxation produced by acetylcholine (ACh). Previous publications suggest that EDRFACh is...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.1.186
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile and atherosclerotic severity to hormone replacement therapy, coronary heart disease risk, and migraine. The roles that reproductive steroi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000181088.76518.ec
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We aimed to determine clinical and hemodynamic predictors of early reocclusion (RO) in stroke patients treated with intravenous tissue plasminogen activator (tPA). METHODS:We studied 142 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with intravenous...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000170711.43405.81
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Autonomic nervous system diseases affect systemic blood pressure regulation. Patients with autonomic nervous system diseases have consistently larger drops in blood pressure associated with standing than the normal population. Autonomic dysfunction and/or these changes in blood pressure may affec...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.9.1686
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:TIMI angiographic classification measures coronary residual flow and recanalization. We developed a Thrombolysis in Brain Ischemia (TIBI) classification by using transcranial Doppler (TCD) to noninvasively monitor intracranial vessel residual flow signals. We examined whether the emergent TCD TIB...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/01.str.32.1.89
更新日期:2001-01-01 00:00:00