Outcomes after carotid artery stenting and endarterectomy in the Medicare population.

abstract：BACKGROUND AND PURPOSE:Elevated leukocyte count has been associated with cardiovascular and cerebrovascular disease in several epidemiological studies. We sought to determine whether white blood cell count (WBC) is associated with carotid plaque thickness in a stroke-free, multiethnic cohort. METHODS:For this cross-se...

journal_title：Stroke

authors： Elkind MS,Cheng J,Boden-Albala B,Paik MC,Sacco RL,Northern Manhattan Stroke Study.

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Functional neuroimaging studies have demonstrated right inferior frontal gyrus (IFG) activation in poststroke aphasia. It remains unclear whether this activation is essential for language performance. We tested this hypothesis in a positron emission tomography (PET) activation study during a sema...

journal_title：Stroke

authors： Winhuisen L,Thiel A,Schumacher B,Kessler J,Rudolf J,Haupt WF,Heiss WD

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile and atherosclerotic severity to hormone replacement therapy, coronary heart disease risk, and migraine. The roles that reproductive steroi...

journal_title：Stroke

authors： Shearman AM,Cooper JA,Kotwinski PJ,Humphries SE,Mendelsohn ME,Housman DE,Miller GJ

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Microvascular basal lamina damage occurs after cerebral ischemia and is important for the development of hemorrhage. The aim of this study was to determine whether hypothermia could maintain microvascular integrity in ischemic stroke. METHODS:Using the suture model, we subjected 12 rats to 3 hou...

journal_title：Stroke

authors： Hamann GF,Burggraf D,Martens HK,Liebetrau M,Jäger G,Wunderlich N,DeGeorgia M,Krieger DW

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dichloroacetate facilitates a decrease in brain lactate during reperfusion after incomplete ischemia. This study examined the possible activation of pyruvate dehydrogenase enzyme by dichloroacetate to explain this effect. Because the duration of ischemia and hyperglycemia exacerbate ischemic brai...

journal_title：Stroke

authors： Dimlich RV,Nielsen MM

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most randomized controlled trials of venous thromboembolism prophylaxis have focused on reduction of deep vein thrombosis, predominantly asymptomatic deep vein thrombosis, detected on imaging. We aimed to estimate the effects of graduated compression stockings on venous thromboembolism events, su...

journal_title：Stroke

authors： CLOTS Trials Collaboration.,Dennis M,Sandercock P,Reid J,Graham C,Murray G,Venables G,Rudd A,Bowler G

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Cardiac involvement in Whipple's disease is not an uncommon phenomenon in autopsies, but its clinical occurrence is often overshadowed by gastrointestinal symptoms. We report a very atypical manifestation of this disorder. SUMMARY OF REPORT:An extraordinary presentation of an extremely long-lasting, culture...

journal_title：Stroke

authors： Naegeli B,Bannwart F,Bertel O

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Methods of performing and reporting randomized clinical trials (RCTs) are available, but weaknesses still occur. For observational studies, methodology is less well described, and weaknesses are even more likely. In recent guidelines for patients with subarachnoid hemorrhage (SAH), 25% of treatme...

journal_title：Stroke

authors： van der Schaaf IC,Ruigrok YM,Rinkel GJ,Algra A,van Gijn J

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The impact of anesthesia technique on the outcomes of mechanical thrombectomy for acute ischemic stroke remains an issue of debate. We investigated the association of general anesthesia with outcomes in patients undergoing mechanical thrombectomy for ischemic stroke. METHODS:We performed a cohor...

journal_title：Stroke

authors： Bekelis K,Missios S,MacKenzie TA,Tjoumakaris S,Jabbour P

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several hundred studies have been published over the last few years on imaging and measurement of carotid stenosis. Despite all this research, there is still no consensus about how best to image and measure stenosis. One possible explanation for this is that many of the studies have not been larg...

journal_title：Stroke

authors： Rothwell PM,Pendlebury ST,Wardlaw J,Warlow CP

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Outcome measurement fidelity within and between sites of multi-site, randomized, clinical trials is an essential element to meaningful trial outcomes. As important are the methods developed for randomized, clinical trials that can have practical utility for clinical practice. A standardized measu...

journal_title：Stroke

authors： Sullivan KJ,Tilson JK,Cen SY,Rose DK,Hershberg J,Correa A,Gallichio J,McLeod M,Moore C,Wu SS,Duncan PW

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Antiplatelet therapy is currently one of the methods for preventing transient ischemic attacks and cerebral thrombosis. Because antiplatelet agents are generally administered on a long-term basis, patient compliance is an important factor. The purpose of this study was to determine the compliance...

journal_title：Stroke

authors： Komiya T,Kudo M,Urabe T,Mizuno Y

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The relationship between the pattern of alcohol intake and the risk of stroke is unclear, in particular the increased risk observed in abstainers and the possible protective effect of light to moderate drinking. For that reason, we examined in a large prospective study the role of alcohol consump...

journal_title：Stroke

authors： Wannamethee SG,Shaper AG

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated low density lipoprotein and reduced high density lipoprotein cholesterol may increase the risk of atherothrombotic brain infarction, but the metabolic mechanisms accounting for this relation are poorly understood. METHODS:The kinetic parameters of low density and high density lipoprotei...

journal_title：Stroke

authors： Alam R,Yatsu FM,Kasturi R,Bui G

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to demonstrate the contribution of axonal remodeling of the corticospinal tract (CST) in the spinal cord to functional outcome after stroke. METHODS:Bilateral pyramidotomy (BPT) or sham-BPT was performed in mice with transgenic yellow fluorescent protein labeling in the CST subjected t...

journal_title：Stroke

authors： Liu Z,Chopp M,Ding X,Cui Y,Li Y

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The role of extracellular Ca2+ in the maintenance of chronic vasospasm after subarachnoid hemorrhage (SAH) is largely unknown. Indeed, studies thus far have been limited to demonstrations that L-type Ca(2+)-channel antagonists were unable to reverse the spasm. This study tested whether SAH-induce...

journal_title：Stroke

authors： Zuccarello M,Boccaletti R,Tosun M,Rapoport RM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The apparent diffusion coefficient (ADC) of water should be sensitive to the cytotoxic edema triggered by energy failure during ischemia. Elevated values of T2. the nuclear MR transverse relaxation time of water, seen on T2 nuclear MR images detect vasogenic edema and infarcted areas. The tempora...

journal_title：Stroke

authors： Loubinoux I,Volk A,Borredon J,Guirimand S,Tiffon B,Seylaz J,Méric P

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We tested the hypothesis that fibrin structure/function is unfavorably altered in patients with cryptogenic ischemic stroke. METHODS:Ex vivo plasma fibrin clot permeability, turbidimetry, and efficiency of fibrinolysis were determined in 89 patients with patent foramen ovale (PFO) and a history ...

journal_title：Stroke

authors： Undas A,Podolec P,Zawilska K,Pieculewicz M,Jedliński I,Stepień E,Konarska-Kuszewska E,Weglarz P,Duszyńska M,Hanschke E,Przewlocki T,Tracz W

更新日期：2009-04-01 00:00:00

abstract：:Experimental subarachnoid hemorrhage (SAH) was induced in baboons by repeated injections of autologous blood into cisterna chiasmatis and cisterna magna, a total of 14-33 ml being injected over 3-4 days. Cerebral blood flow (CBF; 133xenon clearance) and cerebral metabolic rate of oxygen (CMRO2) were measured before, a...

journal_title：Stroke

authors： Sahlin C,Delgado T,Owman C,Svendgaard NA

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our aims were to quantify the yield of Holter monitor for detection of paroxysmal atrial fibrillation (PAF) in patients with stroke and TIA, and to determine potential predictors of PAF to allow more focused testing. METHODS:We reviewed records of 1128 consecutive patients attending a university...

journal_title：Stroke

authors： Alhadramy O,Jeerakathil TJ,Majumdar SR,Najjar E,Choy J,Saqqur M

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Follow-up imaging is often performed in intracranial aneurysms that are not treated. We performed a systematic review and meta-analysis on patient- and aneurysm-specific risk factors for aneurysm growth. METHODS:We searched EMBASE and MEDLINE for cohort studies describing risk factors for aneury...

journal_title：Stroke

authors： Backes D,Rinkel GJ,Laban KG,Algra A,Vergouwen MD

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The neuroprotective role of mild therapeutic hypothermia was established in animal models of cerebral ischemia. Still, several issues, including optimal target temperature, remain unclear. The optimal depth of hypothermia in a rat model of focal cerebral ischemia was investigated. METHODS:Eighty...

journal_title：Stroke

authors： Kollmar R,Blank T,Han JL,Georgiadis D,Schwab S

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:"Incidental" MRI white matter (WM) lesions, comprising periventricular lesions (PVLs) and deep subcortical lesions (DSCLs), are common in the aging brain. Direct evidence of ischemia associated with incidental WM lesions (WMLs) has been lacking, and their pathogenesis is unresolved. METHODS:A po...

journal_title：Stroke

authors： Fernando MS,Simpson JE,Matthews F,Brayne C,Lewis CE,Barber R,Kalaria RN,Forster G,Esteves F,Wharton SB,Shaw PJ,O'Brien JT,Ince PG,MRC Cognitive Function and Ageing Neuropathology Study Group.

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains unknown whether the effects of 0.6 mg/kg alteplase differ with occlusion site of the middle cerebral artery (MCA). We therefore evaluated the effects of 0.6 mg/kg intravenous alteplase in patients with different sites of MCA occlusion. METHODS:An exploratory analysis was made of 57 pa...

journal_title：Stroke

authors： Hirano T,Sasaki M,Mori E,Minematsu K,Nakagawara J,Yamaguchi T,Japan Alteplase Clinical Trial II Group.

更新日期：2010-12-01 00:00:00

abstract：:Acute cerebral circulatory changes following experimental cerebral hemorrhage were investigated in eight cats. The cerebral hemorrhage was produced in the right basal ganglia by introducing arterial blood via a thin catheter, using the systemic arterial blood pressure of the cat as a driving force. Local cerebral bloo...

journal_title：Stroke

authors： Kobari M,Gotoh F,Tomita M,Tanahashi N,Shinohara T,Terayama Y,Mihara B

更新日期：1988-08-01 00:00:00

abstract：:Radiolabelled misonidazole, a radiosensitizing drug that binds to viable hypoxic tumor cells, may be useful in identifying hypoxic cells in cerebrovascular disease. Its potential was investigated in the gerbil stroke model. Biodistribution of [3H]misonidazole was measured in normal gerbils and animals that had been su...

journal_title：Stroke

authors： Hoffman JM,Rasey JS,Spence AM,Shaw DW,Krohn KA

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Posttraumatic stress disorder (PTSD) can be triggered by life-threatening medical events such as strokes and transient ischemic attacks (TIAs). Little is known regarding how PTSD triggered by medical events affects patients' adherence to medications. METHODS:We surveyed 535 participants, age ≥40...

journal_title：Stroke

authors： Kronish IM,Edmondson D,Goldfinger JZ,Fei K,Horowitz CR

更新日期：2012-08-01 00:00:00

abstract：:The hemolysate (10(-5)-10(-2) times dilution; original hemoglobin concentration was 0.83 +/- 0.10 X 10(-3)M) evoked the contraction in a dose dependent manner, and this contraction was composed of low and high sensitive responses as estimated from the Eadie-Hofstee's plot. Indomethacin (10(-7)-10(-5)M) inhibited the l...

journal_title：Stroke

authors： Fujiwara S,Kuriyama H

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Variations in blood-brain barrier (BBB) opening after ischemia have been suggested by some tracer and magnetization transfer studies, although direct in vivo proof is still lacking. Contrast-enhanced magnetic resonance imaging (MRI) is also often used to visualize BBB damage in stroke. We hypothe...

journal_title：Stroke

authors： Nagaraja TN,Karki K,Ewing JR,Croxen RL,Knight RA

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:White matter hyperintensities (WMH) are frequently seen on neuroimaging of elderly and are associated with cognitive decline and the development of dementia. Yet, the temporal dynamics of conversion of normal-appearing white matter (NAWM) into WMH remains unknown. We examined whether and when pro...

journal_title：Stroke

authors： van Leijsen EMC,Bergkamp MI,van Uden IWM,Ghafoorian M,van der Holst HM,Norris DG,Platel B,Tuladhar AM,de Leeuw FE

更新日期：2018-06-01 00:00:00