Different degrees of hypothermia after experimental stroke: short- and long-term outcome.

abstract：BACKGROUND AND PURPOSE:Deep intracerebral hemorrhage (ICH) and lacunar infarcts are the result of small vessel disease, whereas nonlacunar infarcts are often caused by large artery atherosclerosis or cardiac embolism. We hypothesized that patients with deep ICH and lacunar infarcts have similar retinal microvascular si...

journal_title：Stroke

authors： Baker ML,Hand PJ,Liew G,Wong TY,Rochtchina E,Mitchell P,Lindley RI,Hankey GJ,Wang JJ,Multi-Centre Retinal Stroke Study Group.

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although a genetic contribution to ischemic stroke is well recognized, only a handful of stroke loci have been identified by large-scale genetic association studies to date. Hypothesizing that genetic effects might be stronger for early- versus late-onset stroke, we conducted a 2-stage meta-analy...

journal_title：Stroke

authors： Cheng YC,Stanne TM,Giese AK,Ho WK,Traylor M,Amouyel P,Holliday EG,Malik R,Xu H,Kittner SJ,Cole JW,O'Connell JR,Danesh J,Rasheed A,Zhao W,Engelter S,Grond-Ginsbach C,Kamatani Y,Lathrop M,Leys D,Thijs V,Metso TM,

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Reduced arterial distensibility has been introduced as a novel risk factor for atherosclerosis. The importance of the genetic contribution to variation in distensibility is largely unknown. The purpose of this study was to estimate heritability of carotid distensibility. METHODS:The ongoing Nort...

journal_title：Stroke

authors： Juo SH,Rundek T,Lin HF,Cheng R,Lan MY,Huang JS,Boden-Albala B,Sacco RL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been postulated that physiological changes in the cardiovascular system, lipids, and glucose metabolism during pregnancy may increase subsequent risk of cardiovascular disease. Examination of the association between parity and risk factors for atherosclerosis may contribute information reg...

journal_title：Stroke

authors： Humphries KH,Westendorp IC,Bots ML,Spinelli JJ,Carere RG,Hofman A,Witteman JC

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The use of thrombolysis in acute minor ischemic stroke (MIS) remains controversial. We sought to determine the safety and efficacy of intravenous tissue-type plasminogen activator (IV-tPA) in acute MIS patients with demonstrable penumbra on computed tomographic perfusion study. METHODS:Consecuti...

journal_title：Stroke

authors： Ng FC,Coote S,Frost T,Bladin C,Choi PM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cardiovascular and pulmonary factors contributing to impaired peak oxygen uptake (VO2) in patients with stroke (SP) are not well known. We assessed cardiovascular function, pulmonary gas exchange, and ventilation in SP and healthy age, gender, and activity-matched control subjects. METHODS:Ten h...

journal_title：Stroke

authors： Tomczak CR,Jelani A,Haennel RG,Haykowsky MJ,Welsh R,Manns PJ

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There have not been any new epidemiological studies related to stroke in Tibet for 20 years. This study aimed to collect stroke data from The City Staff Medical Insurance Registry in Lhasa, Tibet, to describe the incidence, clinical subtypes, and associated risk factors of stroke. METHODS:We use...

journal_title：Stroke

authors： Zhao Y,Yao Z,D'Souza W,Zhu C,Chun H,Zhuoga C,Zhang Q,Hu X,Zhou D

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We analyzed the impact of detailed anatomic characteristics on the results of endovascular coil embolization for anterior communicating artery (AcoA) aneurysms and developed a predictive model estimating the probability of successful endovascular treatment. METHODS:One hundred eighty-one AcoA an...

journal_title：Stroke

authors： Gonzalez N,Sedrak M,Martin N,Vinuela F

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Mechanisms involved in stroke progression are incompletely understood. Ischemic brain injury is characterized by acute local inflammatory response mediated by cytokines. Anti-inflammatory cytokines act in a feedback loop to inhibit continued proinflammatory cytokine production. We assessed the implication of...

journal_title：Stroke

authors： Vila N,Castillo J,Dávalos A,Esteve A,Planas AM,Chamorro A

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sulcal effacement with preserved underlying gray-white matter junction (isolated sulcal effacement [ISE]) in acute ischemic stroke may not represent irreversible parenchymal injury. We aimed to evaluate the frequency and significance of ISE in patients with large vessel occlusion acute ischemic s...

journal_title：Stroke

authors： Haussen DC,Lima A,Frankel M,Anderson A,Belagaje S,Nahab F,Rangaraju S,Nogueira RG

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A supraphysiological amount of vitamin E in the standard diet of laboratory animals may provide partial protection against cerebral ischemic damage in stroke models. The aim of the present study was to test the effect of dietary vitamin E on infarct volume in rats subjected to permanent focal cer...

journal_title：Stroke

authors： van der Worp HB,Bär PR,Kappelle LJ,de Wildt DJ

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study was to assess the costs and cost-effectiveness of intravenous thrombolysis treatment with alteplase (Actilyse) of acute ischemic stroke with 24-hour in-house neurology coverage and use of magnetic resonance imaging. METHODS:A health economic model was designed to calculate ...

journal_title：Stroke

authors： Ehlers L,Andersen G,Clausen LB,Bech M,Kjølby M

更新日期：2007-01-01 00:00:00

abstract：:To elucidate the connection between blood flow and the localized genesis and development of atherosclerosis and thrombosis at the human carotid artery bifurcation, detailed studies of the flow patterns and distributions of fluid velocity and wall shear rate in this region were carried out using a transparent segment o...

journal_title：Stroke

authors： Motomiya M,Karino T

更新日期：1984-01-01 00:00:00

abstract：:Background and Purpose- Hyperglycemia is a negative prognostic factor after acute ischemic stroke but is not known whether glucose is associated with the effects of endovascular thrombectomy (EVT) in patients with large-vessel stroke. In a pooled-data meta-analysis, we analyzed whether serum glucose is a treatment mod...

journal_title：Stroke

authors： Chamorro Á,Brown S,Amaro S,Hill MD,Muir KW,Dippel DWJ,van Zwam W,Butcher K,Ford GA,den Hertog HM,Mitchell PJ,Demchuk AM,Majoie CBLM,Bracard S,Sibon I,Jadhav AP,Lara-Rodriguez B,van der Lugt A,Osei E,Renú A,Richard

更新日期：2019-03-01 00:00:00

abstract：:In the rat an intracisternal injection of blood induces an angiographically demonstrable biphasic cerebral arterial vasospasm. Chemical destruction of the central serotoninergic and dopaminergic pathways prior to the cisternal blood injection does not affect the spasm pattern after the subarachnoid haemorrhage. It is ...

journal_title：Stroke

authors： Svendgaard NA,Brismar J,Delgado TJ,Rosengren E,Stenevi U

更新日期：1986-01-01 00:00:00

abstract：:Perioperative cerebral infarction occurs in less than 1% of general surgical procedures; the mechanism is usually unknown. The clinical features of 12 consecutive perioperative strokes were retrospectively reviewed. Although intraoperative hypotension was frequent, onset of deficit occurred postoperatively in 83% and ...

journal_title：Stroke

authors： Hart R,Hindman B

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The current work is based on our previous finding that in neuronal cells, nmol/L concentrations of alpha-tocotrienol (TCT), but not alpha-tocopherol (TCP), blocked glutamate-induced death by suppressing early activation of c-Src kinase and 12-lipoxygenase. METHODS:The single neuron microinjectio...

journal_title：Stroke

authors： Khanna S,Roy S,Slivka A,Craft TK,Chaki S,Rink C,Notestine MA,DeVries AC,Parinandi NL,Sen CK

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aspirin is preventive against stroke not only because of its antithrombotic properties but also by other direct effects. The aim of this study was to elucidate its direct neuroprotective effects. METHODS:Viability parameters, glutamate release and uptake, and ATP levels were measured in cultured...

journal_title：Stroke

authors： De Cristóbal J,Cárdenas A,Lizasoain I,Leza JC,Fernández-Tomé P,Lorenzo P,Moro MA

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid angioplasty and stenting (CAS) is associated with higher risk of periprocedural stroke and death when compared with carotid endarterectomy (CEA). By contrast, the risk of myocardial infarction (MI) was higher after CEA than after CAS in randomized trials. However, numbers were small, and ...

journal_title：Stroke

authors： Boulanger M,Camelière L,Felgueiras R,Berger L,Rerkasem K,Rothwell PM,Touzé E

更新日期：2015-10-01 00:00:00

abstract：:Background and Purpose- Many patients with acute ischemic stroke are not eligible for thrombolysis or mechanical reperfusion therapies due to contraindications, inaccessible vascular occlusions, late presentation, or large infarct core. Sphenopalatine ganglion (SPG) stimulation to enhance collateral flow and stabilize...

journal_title：Stroke

authors： Bornstein NM,Saver JL,Diener HC,Gorelick PB,Shuaib A,Solberg Y,Devlin T,Leung T,Molina CA,ImpACT-24A Investigators † .,ImpACT-24A Investigators include the Site Principal Investigators, DSMB members, and the Site Co-Investigators lis

更新日期：2019-05-23 00:00:00

abstract：BACKGROUND AND PURPOSE:Cells lacking the ATM (ataxia telangectasia mutated) gene are hypersensitive to DNA damage caused by a variety of insults. ATM may regulate oxidative stress-induced signaling cascades involving nuclear factor-kappaB (NF-kappaB), a transcription factor that is upstream of a wide variety of stress-...

journal_title：Stroke

authors： Yin KJ,Chen SD,Lee JM,Xu J,Hsu CY

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Flow Diverters (FD) are a new emerging therapy for intracranial aneurysms. Initial reports focused on the treatment of proximally located aneurysms. We report our experience with FDs in the treatment of aneurysms at and beyond the circle of Willis. METHODS:We treated 30 aneurysms at and beyond t...

journal_title：Stroke

authors： Pistocchi S,Blanc R,Bartolini B,Piotin M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Citicoline, a naturally occurring precursor of phosphatidylcholine, is neuroprotective and is currently being assessed in clinical trials. To evaluate potential synergistic neuroprotective effects of prolonged citicoline treatment and early N-methyl-D-aspartate (NMDA) antagonist therapy, suboptim...

journal_title：Stroke

authors： Onal MZ,Li F,Tatlisumak T,Locke KW,Sandage BW Jr,Fisher M

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To improve reproducibility and reliability in the identification of embolic signals detected with the use of Doppler ultrasound, many studies have used an intensity threshold. However, variable thresholds between 3 and 12 dB have been used, and often the method of measurement of intensity is not ...

journal_title：Stroke

authors： Markus HS,Molloy J

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral white matter hyperintensities (WMHs) are believed to be the consequence of small vessel disease, and it is uncertain whether their extent predicts the risk of dementia in patients with vascular disease history. Method- Brain MRI was performed in 226 participants of the PROGRESS study. WM...

journal_title：Stroke

authors： Dufouil C,Godin O,Chalmers J,Coskun O,MacMahon S,Tzourio-Mazoyer N,Bousser MG,Anderson C,Mazoyer B,Tzourio C,PROGRESS MRI Substudy Investigators.

更新日期：2009-06-01 00:00:00

abstract：:Choline concentration is rate limiting in the synthesis of acetylcholine. There is a negative arteriovenous difference for choline concentration across the brain, indicating the steady output of choline from this organ. Cerebral ischemia may increase extracellular choline concentration by interfering with its removal ...

journal_title：Stroke

authors： Scremin OU,Jenden DJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:After stroke, individuals have decreased mobility of the hemiparetic leg, which demands less muscle oxygen consumption; thus, blood flow decreases. The purpose of this study was to determine the effect of single limb exercise (SLE) on femoral artery blood flow, diameter, and peak flow velocity in...

journal_title：Stroke

authors： Billinger SA,Gajewski BJ,Guo LX,Kluding PM

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Embolic complications during ultrasound examinations are a rare cause of neurological deficits. The present case documents the occurrence of embolism by a nonobstructive compression maneuver during transcranial Doppler examination, resulting in a minor stroke. CASE DESCRIPTION:A 63-year-old man ...

journal_title：Stroke

authors： Khaffaf N,Karnik R,Winkler WB,Valentin A,Slany J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study is to investigate whether apocynin, an NADPH oxidase inhibitor, attenuates vasospasm after experimental subarachnoid hemorrhage (SAH) in rats. METHODS:Rats were subjected to endovascular perforation of the right anterior cerebral artery or sham surgery. Beginning 2 hour...

journal_title：Stroke

authors： Zheng JS,Zhan RY,Zheng SS,Zhou YQ,Tong Y,Wan S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because best medical treatment is improving, the risk of stroke in asymptomatic carotid artery stenosis (ACAS) may decline. We evaluated the risk of ischemic stroke and stratified it according to stroke subtype in patients with ACAS during long-term follow-up. METHODS:In total, 4319 consecutive ...

journal_title：Stroke

authors： den Hartog AG,Achterberg S,Moll FL,Kappelle LJ,Visseren FL,van der Graaf Y,Algra A,de Borst GJ,SMART Study Group.

更新日期：2013-04-01 00:00:00