Single limb exercise induces femoral artery remodeling and improves blood flow in the hemiparetic leg poststroke.

Abstract:

BACKGROUND AND PURPOSE:After stroke, individuals have decreased mobility of the hemiparetic leg, which demands less muscle oxygen consumption; thus, blood flow decreases. The purpose of this study was to determine the effect of single limb exercise (SLE) on femoral artery blood flow, diameter, and peak flow velocity in the hemiparetic leg after stroke. METHODS:Twelve individuals (60.6+/-14.5 years of age; 5 male) with chronic stroke (69.1+/-82.2 months; 5 with right-sided hemiparesis) participated in the study. The intervention consisted of a SLE knee extension/flexion protocol 3 times per week for 4 weeks. Using Doppler ultrasound, bilateral femoral artery blood flow, diameter, and peak flow velocity were assessed at baseline, after 2 weeks, and after 4 weeks of SLE. RESULTS:Using repeated-measures analysis of variance, femoral artery blood flow, arterial diameter, and blood flow velocity in the hemiparetic limb were significantly improved (P<0.0001) after the SLE. No significant changes occurred in the nontrained limb for any outcome measures. CONCLUSIONS:These data suggest that a 4-week SLE training program that increases muscular activity in the hemiparetic limb improves femoral artery blood flow, diameter, and peak velocity. SLE may be an important training strategy in stroke rehabilitation to minimize the vascular changes that occur poststroke due to decreased activity of the hemiparetic limb.

journal_name

Stroke

journal_title

Stroke

authors

Billinger SA,Gajewski BJ,Guo LX,Kluding PM

doi

10.1161/STROKEAHA.109.550889

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

3086-90

issue

9

eissn

0039-2499

issn

1524-4628

pii

STROKEAHA.109.550889

journal_volume

40

pub_type

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