Striatal dopamine in acute cerebral ischemia of stroke-resistant rats.

abstract：BACKGROUND AND PURPOSE:The neck clipping of cerebral aneurysms is a well-established treatment for subarachnoid hemorrhage (SAH) caused by aneurysmal rupture. However, it is still unclear how great a risk of recurrence patients with a successfully treated aneurysm carry over a long-term period. METHODS:Of 425 patients...

journal_title：Stroke

authors： Tsutsumi K,Ueki K,Usui M,Kwak S,Kirino T

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:An increase in intima-media thickness (IMT) in the common carotid artery (CCA) is commonly used as a marker of atherosclerosis. The purpose of this study was to investigate the relationship between IMT in the CCA and atherosclerosis in the carotid bifurcation. METHODS:182 consecutive patients (m...

journal_title：Stroke

authors： Rosfors S,Hallerstam S,Jensen-Urstad K,Zetterling M,Carlström C

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pial arterioles transiently dilate during cortical spreading depression (CSD), although the mechanisms are unclear. We tested the hypothesis that increased production of nitric oxide (NO) promotes arteriolar dilation. METHODS:Urethane-anesthetized rabbits were equipped with cranial windows, and ...

journal_title：Stroke

authors： Colonna DM,Meng W,Deal DD,Busija DW

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The relation between symptomatic lacunar infarction, silent stroke, and arterial hypertension is controversial. METHODS:From 500 patients with ischemic or hemorrhagic stroke admitted to the Downtown Barcelona Stroke Registry between July 1992 and December 1994, we evaluated prospectively the pre...

journal_title：Stroke

authors： Chamorro A,Saiz A,Vila N,Ascaso C,Blanc R,Alday M,Pujol J

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The migratory efficiency of mesenchymal stem cells (MSC) toward cerebral infarct after transplantation is limited. Valproate (VPA) and lithium enhance in vitro migration of MSC by upregulating CXC chemokine receptor 4 and matrix metalloproteinase-9, respectively. Ability of VPA and lithium to pro...

journal_title：Stroke

authors： Tsai LK,Wang Z,Munasinghe J,Leng Y,Leeds P,Chuang DM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Improvements in cardiac surgery mortality and morbidity have focused interest on the neurological injury such as stroke and cognitive decline that may accompany an otherwise successful operation. We aimed to investigate (1) the rate of stroke, new ischemic change on MRI, and cognitive impairment ...

journal_title：Stroke

authors： Barber PA,Hach S,Tippett LJ,Ross L,Merry AF,Milsom P

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Symptomatic hemorrhage contributes to an increased risk of repeated bleeding and morbidity in cerebral cavernous malformation (CCM). A better understanding of morbidity after CCM hemorrhage would be helpful to identify patients of higher risk for unfavorable outcome and tailor individualized mana...

journal_title：Stroke

authors： Ma L,Zhang S,Li Z,Wu CX,Wang Z,Zhan L,Hao Q,Wang H,Ye X,Chen X,Liu YO,Wang S,Zhao YL

更新日期：2020-10-01 00:00:00

abstract：:In 24 patients with cerebrovascular disease and 6 without organic brain lesions, the increased velocity of blood flow in both the internal carotid and vertebral arteries during a contralateral carotid compression was compared with the angiographic appearance of the circle of Willis. The flow velocity was measured usin...

journal_title：Stroke

authors： Yoneda S,Nukada T,Kimura K,Tanaka K,Ashida K,Asai T,Etani H,Imaizumi M,Abe H

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To clarify hemodynamic risk factors for hemorrhage in arteriovenous malformations (AVMs), the mean transit time (MTT) of feeding arteries and draining veins in AVMs with and without hemorrhage was measured and analyzed. METHODS:Morphological features such as the number and diameter of draining a...

journal_title：Stroke

authors： Todaka T,Hamada J,Kai Y,Morioka M,Ushio Y

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:20% of ischemic stroke is in the posterior circulation, but there is little prospective data on early recurrent stroke risk and whether vertebrobasilar stenosis predicts a high recurrence risk. This natural history data are important as it is technically possible to stent such lesions. Contrast e...

journal_title：Stroke

authors： Gulli G,Khan S,Markus HS

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild hypothermia is possibly the single most effective method of cerebroprotection developed to date. However, many questions regarding mild hypothermia remain to be addressed before its potential implementation in the treatment of human stroke. Here we report the results of 2 studies designed to...

journal_title：Stroke

authors： Maier CM,Ahern Kv,Cheng ML,Lee JE,Yenari MA,Steinberg GK

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several studies have reported on the correlation of ultrasonic carotid plaque morphology, cerebrovascular symptoms, and intraplaque hemorrhage. This study correlates ultrasonic carotid plaque morphology with the degree of carotid stenosis. METHODS:Carotid arteries (n=2460) were examined by using...

journal_title：Stroke

authors： AbuRahma AF,Wulu JT Jr,Crotty B

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We investigated the effect of hypothermia induced 1 hour after transient (2-hour) middle cerebral artery occlusion on the extent of ischemic cell damage in the rat. METHODS:Middle cerebral artery occlusion was induced extracranially by insertion of a nylon filament into the right internal caroti...

journal_title：Stroke

authors： Zhang RL,Chopp M,Chen H,Garcia JH,Zhang ZG

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We analyzed the impact of detailed anatomic characteristics on the results of endovascular coil embolization for anterior communicating artery (AcoA) aneurysms and developed a predictive model estimating the probability of successful endovascular treatment. METHODS:One hundred eighty-one AcoA an...

journal_title：Stroke

authors： Gonzalez N,Sedrak M,Martin N,Vinuela F

更新日期：2008-10-01 00:00:00

abstract：:Background and Purpose- More intensive secondary prevention with newer drugs may be cost-effective in patients with coronary artery disease (CAD). Whether some subgroups of patients who had a transient ischemic attack (TIA) or ischemic stroke, but no prior CAD are at similar high risk of myocardial infarction as those...

journal_title：Stroke

authors： Boulanger M,Li L,Lyons S,Lovett NG,Kubiak MM,Silver L,Touzé E,Rothwell PM

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke-associated immunosuppression is an increasingly recognized factor triggering infections and thus potentially influencing outcome after stroke. Specifically, lymphocytopenia after intracerebral hemorrhage (ICH) has only been addressed in small-sized retrospective studies of mixed intracrani...

journal_title：Stroke

authors： Giede-Jeppe A,Bobinger T,Gerner ST,Madžar D,Sembill J,Lücking H,Kloska SP,Keil T,Kuramatsu JB,Huttner HB

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent studies have shown the antiapoptotic neuroprotective effects of lecithinized superoxide dismutase (PC-SOD) in different forms of brain injury. We tested the effects of PC-SOD in focal cerebral ischemia in the rat middle cerebral artery occlusion model (MCAO). METHODS:Adult male Sprague-Da...

journal_title：Stroke

authors： Tsubokawa T,Jadhav V,Solaroglu I,Shiokawa Y,Konishi Y,Zhang JH

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Combined Lysis of Thrombus in Brain Ischemia With Transcranial Ultrasound and Systemic T-PA-Hands-Free (CLOTBUST-HF) study is a first-in-human, National Institutes of Health-sponsored, multicenter, open-label, pilot safety trial of tissue-type plasminogen activator (tPA) plus a novel operator...

journal_title：Stroke

authors： Barreto AD,Alexandrov AV,Shen L,Sisson A,Bursaw AW,Sahota P,Peng H,Ardjomand-Hessabi M,Pandurengan R,Rahbar MH,Barlinn K,Indupuru H,Gonzales NR,Savitz SI,Grotta JC

更新日期：2013-12-01 00:00:00

abstract：:To clarify the nature of ischemic striatal dopamine release during the earliest periods of neuronal injury, we used chronoamperometry to measure dopamine levels every 60 seconds during various durations of ischemia in 32 gerbils. Catecholamine-selective electrodes were implanted into the brains of anesthetized gerbils...

journal_title：Stroke

authors： Ahn SS,Blaha CD,Alkire MT,Wood E,Gray-Allan P,Marrocco RT,Moore WS

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Inflammatory and immune mechanisms can precipitate cerebrovascular thrombosis and hemorrhage. Immunologic tolerance can be induced to a specific antigen by intranasal instillation of that antigen. Lymphocytes tolerized in this way provide local immunosuppression on restimulation with the same ant...

journal_title：Stroke

authors： Takeda H,Spatz M,Ruetzler C,McCarron R,Becker K,Hallenbeck J

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The remaining limitations of ultrasonographic imaging in accurately quantifying internal carotid stenosis or diagnosing internal carotid occlusion may be overcome by enhancing the echogenicity of flowing arterial blood with contrast agents. This study assessed the usefulness of the intravenous (t...

journal_title：Stroke

authors： Sitzer M,Fürst G,Siebler M,Steinmetz H

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Striatal GABAergic neuron is known as a key regulator in adult neurogenesis. However, the specific role of striatal GABAergic neuronal activity in the promotion of neurological recovery after ischemic stroke remains unknown. Here, we used optogenetic approach to investigate these effects and mech...

journal_title：Stroke

authors： Jiang L,Li W,Mamtilahun M,Song Y,Ma Y,Qu M,Lu Y,He X,Zheng J,Fu Z,Zhang Z,Yang GY,Wang Y

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acute cocaine use has been temporally associated with aneurysmal subarachnoid hemorrhage (aSAH). This study analyzes the impact of cocaine use on patient presentation, complications, and outcomes. METHODS:Data of patients admitted with aSAH between 1991 and 2009 were reviewed to determine impact...

journal_title：Stroke

authors： Chang TR,Kowalski RG,Caserta F,Carhuapoma JR,Tamargo RJ,Naval NS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The sensitivity of the brain to brief periods of profound ischemia or prolonged periods of modest ischemia mandates an aggressive approach to acute stroke care. Past studies have shown that many stroke patients do not receive acute care in an urgent and timely fashion. The formation of acute stro...

journal_title：Stroke

authors： Alberts MJ,Chaturvedi S,Graham G,Hughes RL,Jamieson DG,Krakowski F,Raps E,Scott P

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Familial aggregation of intracranial aneurysms (IAs) indicates a genetic role in the pathogenesis of this disease. Despite a number of reported susceptibility loci, no disease-causing gene variants have been identified. In this study, we used a parametric genomewide linkage approach to search for...

journal_title：Stroke

authors： Santiago-Sim T,Depalma SR,Ju KL,McDonough B,Seidman CE,Seidman JG,Kim DH

更新日期：2009-03-01 00:00:00

abstract：:The double subarachnoid hemorrhage canine model was used to test the prophylactic value of immunosuppression in the prevention of cerebral vasospasm after subarachnoid hemorrhage. Dogs treated with cyclosporine A following the regimen prescribed for organ transplant procedures in patients showed a significant reductio...

journal_title：Stroke

authors： Peterson JW,Nishizawa S,Hackett JD,Bun T,Teramura A,Zervas NT

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because thromboembolic events are frequently observed in primary antiphospholipid syndrome (PAPS), we assessed the risk factors for new thrombotic episodes. METHODS:Fifty-six PAPS patients (mean age, 37+/-10 years) were prospectively studied for 5 years. The preliminary Sapporo classification cr...

journal_title：Stroke

authors： Turiel M,Sarzi-Puttini P,Peretti R,Rossi E,Atzeni F,Parsons W,Doria A

更新日期：2005-07-01 00:00:00

abstract：:Two hundred fifteen consecutive patients with cerebrovascular events were evaluated prospectively for the incidence and characteristics of headache. Of 163 patients able to communicate, headache occurred in 29% with bland infarcts, 57% with parenchymal hemorrhage, 36% with transient ischemic attacks and 17% with lacun...

journal_title：Stroke

authors： Portenoy RK,Abissi CJ,Lipton RB,Berger AR,Mebler MF,Baglivo J,Solomon S

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke has been shown to alter autonomic function. The purpose of this study was to show the differential effects of stroke localization on autonomic function parameters assessed by heart rate variability (HRV). METHODS:To determine the differential effect of ischemic stroke localization on auto...

journal_title：Stroke

authors： Tokgözoglu SL,Batur MK,Topçuoglu MA,Saribas O,Kes S,Oto A

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is a major cause of death in the People's Republic of China (PRC), and the geographic distribution of stroke death varies substantially. We conducted an ecological analysis to investigate the relationship of prevalence of hypertension and other risk factors with stroke incidence and mortal...

journal_title：Stroke

authors： He J,Klag MJ,Wu Z,Whelton PK

更新日期：1995-12-01 00:00:00