Relationship between intima-media thickness in the common carotid artery and atherosclerosis in the carotid bifurcation.


BACKGROUND AND PURPOSE:An increase in intima-media thickness (IMT) in the common carotid artery (CCA) is commonly used as a marker of atherosclerosis. The purpose of this study was to investigate the relationship between IMT in the CCA and atherosclerosis in the carotid bifurcation. METHODS:182 consecutive patients (mean age, 67 years) referred for carotid duplex scanning were included. We measured IMT and classified plaques by means of a high-resolution ultrasound technique. RESULTS:IMT was correlated to age, male gender, ischemic heart disease, and presence of plaques or stenoses in any of the carotid bifurcations. In men, IMT was larger on the left than on the right side. Plaques were seen in 163 carotid bifurcations, in 45 of these with > 50% stenosis. On the left side but not on the right, there was a correlation between IMT in the CCA and presence of plaques or stenoses in the carotid bifurcation. Echogenic plaques were more common than echolucent, but the latter caused significantly more stenoses. No relationship was found between plaque echogenicity and IMT. CONCLUSIONS:IMT of the CCA is correlated to the degree of atherosclerosis in the carotid bifurcations in general and on the left side also to the presence of plaques or stenoses in the left carotid bifurcation. Our results support earlier observations suggesting faster development of carotid atherosclerosis on the left than on the right side. Echogenic plaques were more common and generally smaller than echolucent plaques, but there was no correlation between plaque echogenicity and IMT.






Rosfors S,Hallerstam S,Jensen-Urstad K,Zetterling M,Carlström C




Has Abstract


1998-07-01 00:00:00














  • Intracranial stent placement for symptomatic intracranial stenosis as part of a clinical trial versus outside a clinical trial.

    abstract:BACKGROUND AND PURPOSE:A high rate of postprocedure complications in the Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis (SAMMPRIS) trial has raised concerns whether such results are representative of intracranial stent placement in actual routine practice. METHODS:Using the Nationwide In...


    pub_type: 杂志文章


    authors: Siddiq F,Adil MM,Norby K,Qureshi AI

    更新日期:2013-12-01 00:00:00

  • Predictors of early arterial reocclusion after tissue plasminogen activator-induced recanalization in acute ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:We aimed to determine clinical and hemodynamic predictors of early reocclusion (RO) in stroke patients treated with intravenous tissue plasminogen activator (tPA). METHODS:We studied 142 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with intravenous...


    pub_type: 杂志文章


    authors: Rubiera M,Alvarez-Sabín J,Ribo M,Montaner J,Santamarina E,Arenillas JF,Huertas R,Delgado P,Purroy F,Molina CA

    更新日期:2005-07-01 00:00:00

  • Telomerase reverse transcriptase upregulation attenuates astrocyte proliferation and promotes neuronal survival in the hypoxic-ischemic rat brain.

    abstract:BACKGROUND AND PURPOSE:Telomerase reverse transcriptase (TERT) is tightly related to the resistance of cells to stress and injury. However, little is known about the roles of TERT in the nervous system. We try to investigate the effects of TERT on the function of astrocytes in developing rat brains subjected to hypoxia...


    pub_type: 杂志文章,收录出版


    authors: Qu Y,Duan Z,Zhao F,Wei D,Zhang J,Tang B,Li J,Yang C,Mu D

    更新日期:2011-12-01 00:00:00

  • Decreased nighttime heart rate variability is associated with increased stroke risk.

    abstract:BACKGROUND AND PURPOSE:Prediction of stroke in healthy individuals is challenging and there is a diurnal variation of stroke onset. We hypothesized that heart rate variability with a focus on nighttime heart rate variability will predict the risk of stroke in apparently healthy middle-age and elderly subjects. METHODS...


    pub_type: 杂志文章


    authors: Binici Z,Mouridsen MR,Køber L,Sajadieh A

    更新日期:2011-11-01 00:00:00

  • Physical activity and stroke incidence: the Harvard Alumni Health Study.

    abstract:BACKGROUND AND PURPOSE:Physiologically, it appears plausible for physical activity to decrease stroke risk; however, epidemiological studies have produced mixed findings. Furthermore, few studies have examined specific kinds and intensities of activities. The purpose of this study was to examine the association between...


    pub_type: 杂志文章


    authors: Lee IM,Paffenbarger RS Jr

    更新日期:1998-10-01 00:00:00

  • Fatal infantile polyarteritis nodosa with predominant central nervous system involvement.

    abstract:BACKGROUND:Infantile polyarteritis nodosa usually presents in children under 2 years of age as a multiorgan system disease with signs of congestive heart failure or renal failure. This disease and Kawasaki disease may share certain clinical and pathological features. CASE DESCRIPTION:We describe a child who first pres...


    pub_type: 杂志文章


    authors: Engel DG,Gospe SM Jr,Tracy KA,Ellis WG,Lie JT

    更新日期:1995-04-01 00:00:00

  • The rtPA (alteplase) 0- to 6-hour acute stroke trial, part A (A0276g) : results of a double-blind, placebo-controlled, multicenter study. Thromblytic therapy in acute ischemic stroke study investigators.

    abstract:BACKGROUND AND PURPOSE:The Thrombolytic Therapy in Acute Ischemic Stroke Study, which started in August of 1991, was designed to assess the efficacy and safety of intravenous rtPA (alteplase) in patients with acute (0 to 6 hours) ischemic stroke. In October 1993 enrollment was halted because of Safety Committee (DMSB) ...


    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Clark WM,Albers GW,Madden KP,Hamilton S

    更新日期:2000-04-01 00:00:00

  • Incidence of cerebral microbleeds in the general population: the Rotterdam Scan Study.

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    authors: Poels MM,Ikram MA,van der Lugt A,Hofman A,Krestin GP,Breteler MM,Vernooij MW

    更新日期:2011-03-01 00:00:00

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    pub_type: 杂志文章


    authors: Barbour PJ,Castaldo JE,Rae-Grant AD,Gee W,Reed JF 3rd,Jenny D,Longennecker J

    更新日期:1994-06-01 00:00:00

  • Urgent carotid surgery and stenting may be safe after systemic thrombolysis for stroke.

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    pub_type: 杂志文章


    authors: Koraen-Smith L,Troëng T,Björck M,Kragsterman B,Wahlgren CM,Swedish Vascular Registry and the Riks-Stroke Collaboration.

    更新日期:2014-03-01 00:00:00

  • Analysis of endoglin expression in normal brain tissue and in cerebral arteriovenous malformations.

    abstract:BACKGROUND AND PURPOSE:A high incidence of arteriovenous malformations (AVMs) is associated with hereditary hemorrhagic telangiectasia type 1. Endoglin, the gene mutated in this disorder, is expressed at reduced levels on blood vessels of these patients. Since endoglin is a component of the transforming growth factor-b...


    pub_type: 杂志文章


    authors: Matsubara S,Bourdeau A,terBrugge KG,Wallace C,Letarte M

    更新日期:2000-11-01 00:00:00

  • Functional and motor outcome 5 years after stroke is equivalent to outcome at 2 months: follow-up of the collaborative evaluation of rehabilitation in stroke across Europe.

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    pub_type: 临床试验,杂志文章,多中心研究


    authors: Meyer S,Verheyden G,Brinkmann N,Dejaeger E,De Weerdt W,Feys H,Gantenbein AR,Jenni W,Laenen A,Lincoln N,Putman K,Schuback B,Schupp W,Thijs V,De Wit L

    更新日期:2015-06-01 00:00:00

  • Monitoring of cerebral autoregulation in head-injured patients.

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    pub_type: 杂志文章


    authors: Czosnyka M,Smielewski P,Kirkpatrick P,Menon DK,Pickard JD

    更新日期:1996-10-01 00:00:00

  • Inaccuracy of angiography in the diagnosis of carotid ulceration.

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    pub_type: 杂志文章


    authors: Eikelboom BC,Riles TR,Mintzer R,Baumann FG,DeFillip G,Lin J,Imparato AM

    更新日期:1983-11-01 00:00:00

  • Low-grade inflammation is a risk factor for clinical stroke events in addition to silent cerebral infarcts in Japanese older hypertensives: the Jichi Medical School ABPM Study, wave 1.

    abstract:BACKGROUND AND PURPOSE:High-sensitivity C-reactive protein (hsCRP), a marker of inflammation, is associated with atherosclerosis, hypertensive target organ damage, and cardiovascular events. In the general Japanese population, the level of hsCRP is reported to be lower than that in Western countries, and the relationsh...


    pub_type: 杂志文章,随机对照试验


    authors: Ishikawa J,Tamura Y,Hoshide S,Eguchi K,Ishikawa S,Shimada K,Kario K

    更新日期:2007-03-01 00:00:00

  • Is elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events?

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    pub_type: 杂志文章


    authors: Greisenegger S,Endler G,Hsieh K,Tentschert S,Mannhalter C,Lalouschek W

    更新日期:2004-07-01 00:00:00

  • Contralateral flow reduction in unilateral stroke: evidence for transhemispheric diaschisis.

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    pub_type: 杂志文章


    authors: Lagrèze HL,Levine RL,Pedula KL,Nickles RJ,Sunderland JS,Rowe BR

    更新日期:1987-09-01 00:00:00

  • Prognosis of high-risk patients with nonoperated symptomatic extracranial carotid tight stenosis.

    abstract::Forty-five patients with symptomatic (20 with transient ischemic attack, 25 with minor stroke) greater than or equal to 75% stenosis of the cervical internal carotid artery had no endarterectomy and received only medical therapy because the surgical risks (severe cardiac disease, chronic obstructive pulmonary disease,...


    pub_type: 杂志文章


    authors: Bogousslavsky J,Despland PA,Regli F

    更新日期:1988-01-01 00:00:00

  • Fish consumption and the risk of stroke: a dose-response meta-analysis.

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    pub_type: 杂志文章,meta分析


    authors: Larsson SC,Orsini N

    更新日期:2011-12-01 00:00:00

  • Association of intraoperative transcranial doppler monitoring variables with stroke from carotid endarterectomy.

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    pub_type: 杂志文章,多中心研究


    authors: Ackerstaff RG,Moons KG,van de Vlasakker CJ,Moll FL,Vermeulen FE,Algra A,Spencer MP

    更新日期:2000-08-01 00:00:00

  • Ischemic stroke subtypes: a population-based study of incidence and risk factors.

    abstract:BACKGROUND AND PURPOSE:There is scant population-based information on incidence and risk factors for ischemic stroke subtypes. METHODS:We identified all 454 residents of Rochester, Minn, with a first ischemic stroke between 1985 and 1989 from the Rochester Epidemiology Project medical records linkage system. We used S...


    pub_type: 杂志文章


    authors: Petty GW,Brown RD Jr,Whisnant JP,Sicks JD,O'Fallon WM,Wiebers DO

    更新日期:1999-12-01 00:00:00

  • Mild hypothermia after intravenous thrombolysis in patients with acute stroke: a randomized controlled trial.

    abstract:BACKGROUND AND PURPOSE:Hypothermia improves outcome in resuscitated patients and newborns with hypoxic brain injury. We studied the safety and feasibility of mild hypothermia in awake patients with stroke after intravenous thrombolysis. METHODS:Patients were randomized 1:1 to mild hypothermia (35°C) or to standard str...


    pub_type: 杂志文章,随机对照试验


    authors: Piironen K,Tiainen M,Mustanoja S,Kaukonen KM,Meretoja A,Tatlisumak T,Kaste M

    更新日期:2014-02-01 00:00:00

  • Impaired dynamic cerebral autoregulation in carotid artery stenosis.

    abstract:BACKGROUND AND PURPOSE:If it could be determined whether cerebral blood flow can be maintained (autoregulated) during transient falls in arterial blood pressure, we might be able to identify patients with carotid stenosis who are at risk of stroke. However, conventional methods of determining autoregulation in such pat...


    pub_type: 杂志文章


    authors: White RP,Markus HS

    更新日期:1997-07-01 00:00:00

  • Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults.

    abstract:BACKGROUND AND PURPOSE:Enlarged perivascular spaces (EPVS) have been associated with aging, increased stroke risk, decreased cognitive function, and vascular dementia. However, the relationship of EPVS with age-related neuropathologies is not well understood. Therefore, the purpose of this study was to assess the neuro...


    pub_type: 杂志文章


    authors: Javierre-Petit C,Schneider JA,Kapasi A,Makkinejad N,Tamhane AA,Leurgans SE,Mehta RI,Barnes LL,Bennett DA,Arfanakis K

    更新日期:2020-09-01 00:00:00

  • Randomized Sham-Controlled Trial of Navigated Repetitive Transcranial Magnetic Stimulation for Motor Recovery in Stroke.

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    pub_type: 杂志文章,随机对照试验


    authors: Harvey RL,Edwards D,Dunning K,Fregni F,Stein J,Laine J,Rogers LM,Vox F,Durand-Sanchez A,Bockbrader M,Goldstein LB,Francisco GE,Kinney CL,Liu CY,NICHE Trial Investigators *.

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  • High Serum Level of Matrix Metalloproteinase-7 Is Associated With Increased Risk of Spontaneous Subarachnoid Hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Increased degradation of the extracellular matrix in the arterial wall by matrix metalloproteinases (MMPs) may be an important mechanism in the pathogenesis of intracranial aneurysms and subarachnoid hemorrhage (SAH). MMP-2 and MMP-9 have been suggested to be involved in matrix degradation preced...


    pub_type: 杂志文章


    authors: Söderholm M,Nordin Fredrikson G,Nilsson J,Engström G

    更新日期:2018-07-01 00:00:00

  • Impact of pretreatment noncontrast CT Alberta Stroke Program Early CT Score on clinical outcome after intra-arterial stroke therapy.

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    pub_type: 杂志文章,多中心研究


    authors: Yoo AJ,Zaidat OO,Chaudhry ZA,Berkhemer OA,González RG,Goyal M,Demchuk AM,Menon BK,Mualem E,Ueda D,Buell H,Sit SP,Bose A,Penumbra Pivotal and Penumbra Imaging Collaborative Study (PICS) Investigators.

    更新日期:2014-03-01 00:00:00

  • Late measures of brain injury after neonatal hypoxia-ischemia in mice.

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    pub_type: 杂志文章


    authors: Ten VS,Wu EX,Tang H,Bradley-Moore M,Fedarau MV,Ratner VI,Stark RI,Gingrich JA,Pinsky DJ

    更新日期:2004-09-01 00:00:00

  • Intracerebral hematomas disappear on T2*-weighted images during normobaric oxygen therapy.

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    pub_type: 杂志文章


    authors: Gaberel T,Gakuba C,Hebert M,Montagne A,Agin V,Rubio M,Emery E,Vivien D,Gauberti M

    更新日期:2013-12-01 00:00:00

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    pub_type: 杂志文章


    authors: Guerrini U,Sironi L,Tremoli E,Cimino M,Pollo B,Calvio AM,Paoletti R,Asdente M

    更新日期:2002-03-01 00:00:00