Analysis of mean transit time of contrast medium in ruptured and unruptured arteriovenous malformations: a digital subtraction angiographic study.

abstract：BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...

journal_title：Stroke

authors： Kuroda S,Shiga T,Houkin K,Ishikawa T,Katoh C,Tamaki N,Iwasaki Y

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We earlier reported that risk factors for stroke prepare brain stem tissue for a modified Shwartzman reaction, including the development of ischemia and hemorrhage and the production of tumor necrosis factor-alpha, after a provocative dose of lipopolysaccharide. In the present study, we sought to...

journal_title：Stroke

authors： Sirén AL,Liu Y,Feuerstein G,Hallenbeck JM

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity, reflecting active, multifocal bleeding or a variable bleeding time course, would predict ICH growth. METHODS:Three raters examined baseline su...

journal_title：Stroke

authors： Barras CD,Tress BM,Christensen S,MacGregor L,Collins M,Desmond PM,Skolnick BE,Mayer SA,Broderick JP,Diringer MN,Steiner T,Davis SM,Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators.

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The ability of therapeutic exercise after stroke to improve daily functioning and quality of life (QOL) remains controversial. We examined treatment effects on these outcomes in a randomized controlled trial (RCT) of exercise in subacute stroke survivors. METHODS:This is a secondary analysis of ...

journal_title：Stroke

authors： Studenski S,Duncan PW,Perera S,Reker D,Lai SM,Richards L

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to determine the effect of intracisternal administration of an endothelin-A receptor antagonist (BQ-123) against vasospasm in a monkey model and to determine whether this drug would have adverse interactions with intracisternal tissue plasminogen activator (TPA). METHODS:Thirty-three mo...

journal_title：Stroke

authors： Kim CJ,Bassiouny M,Macdonald RL,Weir B,Johns LM

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Parental stroke has been related to an increased risk of stroke in the offspring. This study examines whether parental stroke is also associated with increased vascular brain injury and poorer cognitive performance among offspring free of clinical stroke. METHODS:Multivariable regression analyse...

journal_title：Stroke

authors： Weinstein G,Beiser AS,Au R,Decarli C,Wolf PA,Seshadri S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:MRI has become increasingly used in the acute setting to manage patients with stroke. There has been concern that MRI may not be sensitive in the detection of acute intracranial hemorrhage. We assessed whether strongly susceptibility-weighted MRI would be sensitive to intraparenchymal hemorrhage in the first...

journal_title：Stroke

authors： Patel MR,Edelman RR,Warach S

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Vasogenic brain edema is a frequent complication of ischemic stroke. The mechanism of the blood-brain barrier opening that underlies the edema formation is poorly understood. In the present study we examined the response of endothelial cells cultured from adult human brain to thrombogenic and fib...

journal_title：Stroke

authors： Nagy Z,Kolev K,Csonka E,Pék M,Machovich R

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although chemokines have been implicated in cardiovascular diseases, few studies have addressed the role of these inflammatory mediators in ischemic stroke. This study tested the hypothesis that RANTES (CCL5; regulated on activation, normal T-cell expressed and secreted) mediates the cerebral mic...

journal_title：Stroke

authors： Terao S,Yilmaz G,Stokes KY,Russell J,Ishikawa M,Kawase T,Granger DN

更新日期：2008-09-01 00:00:00

abstract：:The nature of alpha-adrenergic receptors in human cerebral arteries was characterized, and alteration of these receptors after subarachnoid hemorrhage was examined using a radioligand binding assay. Norepinephrine content of control arteries was also analyzed and compared with that of arteries after subarachnoid hemor...

journal_title：Stroke

authors： Tsukahara T,Taniguchi T,Miwa S,Shimohama S,Fujiwara M,Nishikawa M,Handa H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The National Institutes of Health Stroke Scale (NIHSS) is a valid, reproducible scale that measures neurological deficit. Of 42 possible points, 7 points are directly related to measurement of language compared with only 2 points related to neglect. METHODS:We examined the placebo arm of the NIN...

journal_title：Stroke

authors： Woo D,Broderick JP,Kothari RU,Lu M,Brott T,Lyden PD,Marler JR,Grotta JC

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The association between hyperthermia and early neurological deterioration, increased morbidity, and mortality in acute ischemic stroke is well known. However, the timing at which the cerebral lesion may be aggravated by high temperature has not been firmly established. The aim of this study was t...

journal_title：Stroke

authors： Castillo J,Dávalos A,Marrugat J,Noya M

更新日期：1998-12-01 00:00:00

abstract：:Background and Purpose- The complexity and heterogeneity of stroke, as well as the associated comorbidities, may render neuroprotective drugs less efficacious in clinical practice. Therefore, the development of targeted therapies to specific patient subsets has become a high priority in translational stroke research. ...

journal_title：Stroke

authors： Jiang Y,Liu N,Wang Q,Yu Z,Lin L,Yuan J,Guo S,Ahn BJ,Wang XJ,Li X,Lo EH,Sun X,Wang X

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Citicoline, a naturally occurring precursor of phosphatidylcholine, is neuroprotective and is currently being assessed in clinical trials. To evaluate potential synergistic neuroprotective effects of prolonged citicoline treatment and early N-methyl-D-aspartate (NMDA) antagonist therapy, suboptim...

journal_title：Stroke

authors： Onal MZ,Li F,Tatlisumak T,Locke KW,Sandage BW Jr,Fisher M

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral blood flow after cardiac arrest is reduced during the delayed hypoperfusion phase, while cerebral metabolic rate of oxygen returns to baseline values. Hypocapnia can induce cerebral ischemia in neurosurgical patients who already have reduced cerebral blood flow. The purpose of the presen...

journal_title：Stroke

authors： Buunk G,van der Hoeven JG,Meinders AE

更新日期：1997-08-01 00:00:00

abstract：:Cerebral venous blood gas tensions were correlated with elevated intracranial pressure in spontaneously breathing dogs lightly anesthetized with nitrous oxide/halothane. Intracranial pressure was elevated by infusion of artificial cerebrospinal fluid into a lateral ventricle. Respiration and blood pressure were monito...

journal_title：Stroke

authors： Grady PA,Blaumanis OR

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pial arterioles transiently dilate during cortical spreading depression (CSD), although the mechanisms are unclear. We tested the hypothesis that increased production of nitric oxide (NO) promotes arteriolar dilation. METHODS:Urethane-anesthetized rabbits were equipped with cranial windows, and ...

journal_title：Stroke

authors： Colonna DM,Meng W,Deal DD,Busija DW

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The influence of dietary protein intake on stroke risk is an area of interest. We investigated the association between dietary protein intake and stroke risk in Japanese, considering sources of protein. METHODS:A total of 2400 subjects aged 40 to 79 years were followed up for 19 years. Dietary p...

journal_title：Stroke

authors： Ozawa M,Yoshida D,Hata J,Ohara T,Mukai N,Shibata M,Uchida K,Nagata M,Kitazono T,Kiyohara Y,Ninomiya T

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The inflammatory response within cerebral infarcts may have an influence on tissue damage. Since old animals with an impaired immune response have decreased inflammation after experimental cerebral infarction, we postulated that female animals with an increased immune response will have an increa...

journal_title：Stroke

authors： Li K,Futrell N,Tovar S,Wang LC,Wang DZ,Schultz LR

更新日期：1996-03-01 00:00:00

abstract：:Both platelet activating factor and eicosanoids participate in the cerebrovascular response to ischemia. Eicosanoids also modulate cerebrovascular tone under normal physiologic circumstances, but a similar role for platelet activating factor has not been investigated. Therefore, using 16 rats, we studied the effects o...

journal_title：Stroke

authors： Kochanek PM,Melick JA,Schoettle RJ,Magargee MJ,Evans RW,Nemoto EM

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To compare the utility of contrast-enhanced MR Angiography (CE-MRA) with digital subtraction angiography (DSA) after endovascular treatment of intracranial aneurysms with Guglielmi detachable coils. METHODS:From April 1999 to August 2002, 106 patients with 107 aneurysms treated by endovascular c...

journal_title：Stroke

authors： Gauvrit JY,Leclerc X,Caron S,Taschner CA,Lejeune JP,Pruvo JP

更新日期：2006-04-01 00:00:00

abstract：:Brief episodes of ischemia can protect against subsequent damaging ischemic events; however, the molecular mechanisms responsible for protection are poorly understood. Identifying genes involved in this process could provide insight into cell survival and treatment of stroke. We developed a murine model of ischemic pr...

journal_title：Stroke

authors： Stenzel-Poore MP,Stevens SL,Simon RP

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Urinary incontinence in the acute stage of stroke is seen as a predictor of death, severe disability, and an important factor on hospital discharge destination. Therefore, it is an important measure of stroke severity that not only affects the lives of stroke survivors but also those of caregivers. SUMMARY ...

journal_title：Stroke

authors： Brittain KR,Peet SM,Castleden CM

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Variation in the outcome after aneurysmal subarachnoid hemorrhage (SAH) is not fully explained by known prognostic factors. APOE genotype is the most important genetic determinant of susceptibility to Alzheimer's disease, and it is also shown to be associated with the outcome after traumatic brai...

journal_title：Stroke

authors： Niskakangas T,Ohman J,Niemelä M,Ilveskoski E,Kunnas TA,Karhunen PJ

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The majority of ischemic stroke patients receiving endovascular recanalization therapy (EVT) experience variable changes of neurological severities during the hyperacute period. We hypothesized that the National Institutes of Health Stroke Scale (NIHSS) score after EVT is a better prognostic fact...

journal_title：Stroke

authors： Jeong HG,Kim BJ,Choi JC,Hong KS,Yang MH,Jung C,Han MK,Bae HJ

更新日期：2018-04-01 00:00:00

abstract：:We measured cerebrovascular reactivity to carbon dioxide in the cerebral cortex and the subcortical white matter of 12 healthy adult volunteers (four young subjects aged 21-24, four middle-aged subjects aged 34-40, and four elderly subjects aged 62-85 years). Blood flow was computed from the concentration history of x...

journal_title：Stroke

authors： Reich T,Rusinek H

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent studies have shown the antiapoptotic neuroprotective effects of lecithinized superoxide dismutase (PC-SOD) in different forms of brain injury. We tested the effects of PC-SOD in focal cerebral ischemia in the rat middle cerebral artery occlusion model (MCAO). METHODS:Adult male Sprague-Da...

journal_title：Stroke

authors： Tsubokawa T,Jadhav V,Solaroglu I,Shiokawa Y,Konishi Y,Zhang JH

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The introduction of cereal grain folic acid fortification in 1998 has reduced homocyst(e)ine (tHcy) concentrations in the US population. We performed a case-control study to determine the risk of stroke and transient ischemic attack (TIA) associated with tHcy and low vitamin status in a postforti...

journal_title：Stroke

authors： Kelly PJ,Shih VE,Kistler JP,Barron M,Lee H,Mandell R,Furie KL

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV(1)) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is no...

journal_title：Stroke

authors： Söderholm M,Zia E,Hedblad B,Engström G

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite the reported functional recovery in transplanted stroke models and patients, the mechanism of action underlying stem cell therapy remains not well understood. Here, we examined the role of stem cell-mediated vascular repair in stroke. METHODS:Adult rats were exposed to transient occlusio...

journal_title：Stroke

authors： Ishikawa H,Tajiri N,Shinozuka K,Vasconcellos J,Kaneko Y,Lee HJ,Mimura O,Dezawa M,Kim SU,Borlongan CV

更新日期：2013-12-01 00:00:00