Gender influences the magnitude of the inflammatory response within embolic cerebral infarcts in young rats.

abstract：:Background and Purpose- Ischemic stroke is one of the leading causes of morbidity and mortality worldwide and a major cause of long-term disability. Recently, long noncoding RNAs have been revealed, which are tightly associated with several human diseases. However, the functions of long noncoding RNAs in ischemic stro...

journal_title：Stroke

authors： Deng Y,Chen D,Wang L,Gao F,Jin B,Lv H,Zhang G,Sun X,Liu L,Mo D,Ma N,Song L,Huo X,Yan T,Miao Z

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with cerebral amyloid angiopathy (CAA) are at high risk for intracerebral hemorrhage (ICH), but no effective prevention strategies have been established. The objective is to determine whether lowering of blood pressure (BP) provides protection for this high-risk patient group. METHODS:T...

journal_title：Stroke

authors： Arima H,Tzourio C,Anderson C,Woodward M,Bousser MG,MacMahon S,Neal B,Chalmers J,PROGRESS Collaborative Group.

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The integrin-linked kinase (ILK) signaling pathway contributes to regulation of cellular adhesion, migration, and differentiation, and to apoptotic cell death after a variety of cell death stimuli. We have reported that overexpression of copper/zinc superoxide dismutase (SOD1) reduces apoptotic c...

journal_title：Stroke

authors： Saito A,Hayashi T,Okuno S,Nishi T,Chan PH

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Admission infarct core lesion size is an important determinant of management and outcome in acute (<9 hours) stroke. Our purposes were to: (1) determine the optimal CT perfusion parameter to define infarct core using various postprocessing platforms; and (2) establish the degree of variability in...

journal_title：Stroke

authors： Kamalian S,Kamalian S,Maas MB,Goldmacher GV,Payabvash S,Akbar A,Schaefer PW,Furie KL,Gonzalez RG,Lev MH

更新日期：2011-07-01 00:00:00

abstract：:Patients with chronic aphasia were assigned randomly to a group to receive either conventional aphasia therapy or constraint-induced (CI) aphasia therapy, a new therapeutic technique requiring intense practice over a relatively short period of consecutive days. CI aphasia therapy is realized in a communicative therape...

journal_title：Stroke

authors： Pulvermüller F,Neininger B,Elbert T,Mohr B,Rockstroh B,Koebbel P,Taub E

更新日期：2001-07-01 00:00:00

abstract：:Seventy-four patients with hypertensive putaminal hemorrhage (HPH) were followed at least 6 months after treatment and estimated by ADL. They were graded according to the state of consciousness on admission. The grading consists of 6 grades: Grade 1, fully conscious; Grade 2, somnolent; Grade 3, stuporous; Grade 4, se...

journal_title：Stroke

authors： Waga S,Yamamoto Y

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic therapy with recombinant tissue plasminogen activator (rtPA) after stroke increases risk of hemorrhagic transformation, particularly in areas with blood-brain barrier leakage. Our aim was to characterize acute effects of rtPA administration on the integrity of microvascular barriers....

journal_title：Stroke

authors： Dijkhuizen RM,Asahi M,Wu O,Rosen BR,Lo EH

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A supraphysiological amount of vitamin E in the standard diet of laboratory animals may provide partial protection against cerebral ischemic damage in stroke models. The aim of the present study was to test the effect of dietary vitamin E on infarct volume in rats subjected to permanent focal cer...

journal_title：Stroke

authors： van der Worp HB,Bär PR,Kappelle LJ,de Wildt DJ

更新日期：1998-05-01 00:00:00

abstract：:Background and Purpose- Enhancement of erythrophagocytosis by macrophages in a timely manner can limit the toxic effects of erythrocyte metabolites and promote brain recovery after intracerebral hemorrhage (ICH). In the current study, we investigated the therapeutic effect of retinoid X receptor agonist, bexarotene, i...

journal_title：Stroke

authors： Chang CF,Massey J,Osherov A,Angenendt da Costa LH,Sansing LH

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...

journal_title：Stroke

authors： Kuroda S,Shiga T,Houkin K,Ishikawa T,Katoh C,Tamaki N,Iwasaki Y

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Calcium (Ca(2+)) plays a role in the cellular and molecular pathways of ischemic neuronal death. We evaluated the impact of both early and delayed Ca(2+) levels on clinical outcomes from acute ischemic stroke. METHODS:The relations between blood calcium level obtained early (<4.5 hours), and del...

journal_title：Stroke

authors： Ovbiagele B,Starkman S,Teal P,Lyden P,Kaste M,Davis SM,Hacke W,Fierus M,Saver JL,VISTA Investigators.

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Arteriopathy is common in childhood arterial ischemic stroke (AIS) and predicts stroke recurrence. Currently available vascular imaging techniques mainly image the arterial lumen rather than the vessel wall and have a limited ability to differentiate among common arteriopathies. We aimed to inves...

journal_title：Stroke

authors： Dlamini N,Yau I,Muthusami P,Mikulis DJ,Elbers J,Slim M,Askalan R,MacGregor D,deVeber G,Shroff M,Moharir M

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia is common after stroke and is a marker of poor prognosis. Early identification is important. This article reviews the merits and limitations of various assessment methods available to clinicians. METHODS:An electronic database search was performed of MEDLINE, EMBASE, and the Cochrane d...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In most European societies and in the United States, the percentage of patients ≥80 years has been rising over the past century. The present study was conducted to observe this demographic change and its impact on patients with intracerebral hemorrhage (ICH). METHODS:We reviewed patients' data w...

journal_title：Stroke

authors： Stein M,Misselwitz B,Hamann GF,Scharbrodt W,Schummer DI,Oertel MF

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It remains uncertain whether lower dose intravenous tissue-type plasminogen activator (tPA) for stroke is as effective and safe as the standard dose. METHODS:We analyzed data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China). Patients who were treate...

journal_title：Stroke

authors： Liao X,Wang Y,Pan Y,Wang C,Zhao X,Wang DZ,Wang C,Liu L,Wang Y,Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators.

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In Rivaroxaban Once Daily Oral Direct Factor Xa Inhibitor Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial, rivaroxaban was noninferior to dose-adjusted warfarin in preventing stroke or systemic embolism among patients with no...

journal_title：Stroke

authors： Wong KS,Hu DY,Oomman A,Tan RS,Patel MR,Singer DE,Breithardt G,Mahaffey KW,Becker RC,Califf R,Fox KA,Berkowitz SD,Hacke W,Hankey GJ,Executive Steering Committee and the ROCKET AF Study Investigators.

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:TIMI angiographic classification measures coronary residual flow and recanalization. We developed a Thrombolysis in Brain Ischemia (TIBI) classification by using transcranial Doppler (TCD) to noninvasively monitor intracranial vessel residual flow signals. We examined whether the emergent TCD TIB...

journal_title：Stroke

authors： Demchuk AM,Burgin WS,Christou I,Felberg RA,Barber PA,Hill MD,Alexandrov AV

更新日期：2001-01-01 00:00:00

abstract：:The methionine analogue methionine sulfoximine was administered to 10 rats 24 hours before occlusion of the proximal left middle cerebral artery. Three days later the rats were decapitated and the brain infarct volumes were compared with those in 10 control rats that received saline before middle cerebral artery occlu...

journal_title：Stroke

authors： Swanson RA,Shiraishi K,Morton MT,Sharp FR

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracerebral hemorrhage (ICH) is a devastating disease without a proven therapy to improve long-term outcome. Considerable controversy about the role of surgery remains. Minimally invasive endoscopic surgery for ICH offers the potential of improved neurological outcome. METHODS:We tested the hy...

journal_title：Stroke

authors： Vespa P,Hanley D,Betz J,Hoffer A,Engh J,Carter R,Nakaji P,Ogilvy C,Jallo J,Selman W,Bistran-Hall A,Lane K,McBee N,Saver J,Thompson RE,Martin N,ICES Investigators.

更新日期：2016-11-01 00:00:00

abstract：:TCD recording of flow velocities in intracranial vessels was first described by Aaslid in 1982. The utility of this instrument becomes more apparent as it is used in different clinical settings and compared with angiographic findings (Figures 1 and 2). Its importance in early detection of vasospasm in subarachnoid hem...

journal_title：Stroke

authors： DeWitt LD,Wechsler LR

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to identify variables associated with intracerebral hemorrhage in patients with acute ischemic stroke who receive tissue plasminogen activator (t-PA). METHODS:We performed subgroup analyses of data from a randomized, double-blind, placebo-controlled trial of intravenous t-PA administer...

journal_title：Stroke

authors：

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It was found that glutamate, a major neurotransmitter, is vasoactive in the cerebral circulation. However, the mechanism is unclear. This study was designed to investigate the role of nitric oxide (NO) and N-methyl-D-aspartate (NMDA) receptors in cerebral arteriolar dilation to glutamate. METHOD...

journal_title：Stroke

authors： Meng W,Tobin JR,Busija DW

更新日期：1995-05-01 00:00:00

abstract：:The effects of halothane on intracellular membrane potential (Em) and force development in cat MCA were studied. Halothane (0.07-0.14 mM/1) relaxed isolated MCA which had developed myogenic tone. Measurement of Em showed that halothane depolarized this preparation in a dose-dependent fashion in the face of vessel rela...

journal_title：Stroke

authors： Harder DR,Gradall K,Madden JA,Kampine JP

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is a major risk factor for ischemic stroke and its prevalence increases steeply with age. Population-based data on its influence on stroke outcome are scarce. METHODS:We evaluated the prevalence of AF and its influence on prognosis in patients with a first-ever ischemic ...

journal_title：Stroke

authors： Marini C,De Santis F,Sacco S,Russo T,Olivieri L,Totaro R,Carolei A

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Animal studies have shown that MR diffusion imaging can outline acute ischemic regions before irreversible damage (infarction) occurs. To study evolution of ischemic lesions in humans, it is therefore important to quantify absolute diffusion constants (D values), but quantitation has not been rep...

journal_title：Stroke

authors： Uluğ AM,Beauchamp N Jr,Bryan RN,van Zijl PC

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate the direct costs of acute hospitalization for patients with first-ever ischemic stroke in Taiwan. METHODS:Data were prospectively collected from 360 first-ever ischemic stroke patients. Hospital charges were used for analysis. Multiple linear regression analysis was used...

journal_title：Stroke

authors： Chang KC,Tseng MC

更新日期：2003-11-01 00:00:00

abstract：:Background and Purpose- Prestroke dependence is an exclusion criterion in most trials of endovascular treatment (EVT) for acute ischemic stroke. Little is known about outcomes after EVT in these patients. We compared outcome and safety of EVT between prestroke-dependent and prestroke-independent patients. Methods- We ...

journal_title：Stroke

authors： Goldhoorn RB,Verhagen M,Dippel DWJ,van der Lugt A,Lingsma HF,Roos YBWEM,Majoie CBLM,Vos JA,Boiten J,van Zwam WH,van Oostenbrugge RJ,van den Wijngaard I,MR CLEAN Registry Investigators.

更新日期：2018-10-01 00:00:00

abstract：:Background and Purpose- Carotid web (CW) is a rare form of focal fibromuscular dysplasia defined as an abnormal shelf-like projection of intimal fibrous tissue into the carotid bulb. It is theorized that CW leads to ischemic stroke secondary to blood flow stasis and subsequent embolization. The natural history and opt...

journal_title：Stroke

authors： Zhang AJ,Dhruv P,Choi P,Bakker C,Koffel J,Anderson D,Kim J,Jagadeesan B,Menon BK,Streib C

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Thrombolytic Therapy in Acute Ischemic Stroke Study, which started in August of 1991, was designed to assess the efficacy and safety of intravenous rtPA (alteplase) in patients with acute (0 to 6 hours) ischemic stroke. In October 1993 enrollment was halted because of Safety Committee (DMSB) ...

journal_title：Stroke

authors： Clark WM,Albers GW,Madden KP,Hamilton S

更新日期：2000-04-01 00:00:00

abstract：:The hydrogen clearance method was used to measure local and total cerebral blood flow (CBF) in the rhesus monkey before and for five hours after a simulated subarachnoid hemorrhage (SAH). CBF remained stable after SAH unless SAH was associated with a fall in cerebral perfusion pressure. In addition, cerebrovascular re...

journal_title：Stroke

authors： Martins AN,Doyle TF,Newby N,Kobrine AI,Ramirez A

更新日期：1975-11-01 00:00:00