The effect of a simulated subarachnoid hemorrhage on cerebral blood flow in the monkey.

Abstract:

:The hydrogen clearance method was used to measure local and total cerebral blood flow (CBF) in the rhesus monkey before and for five hours after a simulated subarachnoid hemorrhage (SAH). CBF remained stable after SAH unless SAH was associated with a fall in cerebral perfusion pressure. In addition, cerebrovascular resistance did not increase after SAH. These results suggest that vasoactive agents in fresh whole blood, and the arterial spasm they produce when added to cerebrospinal fluid (CSF), play only a limited role in the pathogenesis of ischemic encephalopathy that follows an SAH.

journal_name

Stroke

journal_title

Stroke

authors

Martins AN,Doyle TF,Newby N,Kobrine AI,Ramirez A

doi

10.1161/01.str.6.6.664

subject

Has Abstract

pub_date

1975-11-01 00:00:00

pages

664-72

issue

6

eissn

0039-2499

issn

1524-4628

journal_volume

6

pub_type

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