Delayed cerebral ischemia following arteriography.

abstract：:We observed the effects of a new thyrotropin-releasing hormone derivative, YM-14673 (N alpha-[[(S)-4-oxo-2-azetidinyl]carbonyl]-L-histidyl-L-prolinamide dihydrate), on behavioral changes in rats for 3 weeks after focal cerebral ischemia. Under halothane anesthesia, the left middle cerebral artery was occluded via a tr...

journal_title：Stroke

authors： Yamamoto M,Tamura A,Kirino T,Shimizu M,Sano K

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hyperglycemia enhances the deleterious effect of global cerebral ischemia. One possible explanation is that increased anaerobic glycolysis leads to exaggeration of intracellular acidosis and increased postischemic edema. To examine the importance of this edema on postischemic cerebral perfusion d...

journal_title：Stroke

authors： Morimoto Y,Morimoto Y,Warner DS,Pearlstein RD

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to identify the most powerful binary measures of the treatment effect of tissue plasminogen activator (tPA) in the National Institute of Neurological Disorders and Stroke (NINDS) rTPA Stroke Trial. METHODS:Using the Classification and Regression Tree (CART) algorithm, we evaluated bina...

journal_title：Stroke

authors： Broderick JP,Lu M,Kothari R,Levine SR,Lyden PD,Haley EC,Brott TG,Grotta J,Tilley BC,Marler JR,Frankel M

更新日期：2000-10-01 00:00:00

abstract：:Brain injury, including ischemia, changes normal astrocytes into reactive species that hypertrophy and begin to proliferate. Understanding the mechanisms that underlie these changes could lead to new abilities to promote regeneration and retard neural degeneration after ischemia. Because ionic changes occur after nonn...

journal_title：Stroke

authors： Kraig RP,Jaeger CB

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little information is available regarding black-white differences in stroke incidence in young adults. METHODS:Cerebral infarction and intracerebral hemorrhage rates among adults 15 to 44 years of age were studied in Baltimore City and Baltimore County for 1988. Diagnoses were based on neurologi...

journal_title：Stroke

authors： Kittner SJ,McCarter RJ,Sherwin RW,Sloan MA,Stern BJ,Johnson CJ,Buchholz D,Seipp MJ,Price TR

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Waist circumference has been shown to be a better predictor of cardiovascular risk than body mass index (BMI). Our case-control study aimed to evaluate the contribution of obesity and abdominal fat mass to the risk of stroke and transient ischemic attacks (TIA). METHODS:We recruited 1137 partici...

journal_title：Stroke

authors： Winter Y,Rohrmann S,Linseisen J,Lanczik O,Ringleb PA,Hebebrand J,Back T

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because best medical treatment is improving, the risk of stroke in asymptomatic carotid artery stenosis (ACAS) may decline. We evaluated the risk of ischemic stroke and stratified it according to stroke subtype in patients with ACAS during long-term follow-up. METHODS:In total, 4319 consecutive ...

journal_title：Stroke

authors： den Hartog AG,Achterberg S,Moll FL,Kappelle LJ,Visseren FL,van der Graaf Y,Algra A,de Borst GJ,SMART Study Group.

更新日期：2013-04-01 00:00:00

abstract：:In a postasphyxia neonatal lamb model, the responses of the cerebral circulation to hypoxic hypoxia and changes in systemic arterial blood pressure were examined. Ventilated newborn lambs (n = 14) were subjected to a gradual asphyxial insult, resuscitated, and returned to control ventilator settings. During the time 2...

journal_title：Stroke

authors： Rosenberg AA

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Progression of asymptomatic carotid artery stenosis (ACAS) in patients with >50% luminal narrowing is considered a potential risk factor for ischemic stroke; however, subclinical molecular biomarkers of ACAS progression are lacking. Recent studies suggest a regulatory function for several microRN...

journal_title：Stroke

authors： Dolz S,Górriz D,Tembl JI,Sánchez D,Fortea G,Parkhutik V,Lago A

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In 15% to 20% of patients with a spontaneous subarachnoid hemorrhage, no aneurysm is found on the first angiogram. This review emphasizes that this group of patients is in fact heterogeneous and describes the clinical features, pattern of hemorrhage on early computed tomographic (CT) scan, prognosis, and pro...

journal_title：Stroke

authors： Rinkel GJ,van Gijn J,Wijdicks EF

更新日期：1993-09-01 00:00:00

abstract：:An anecdotal series of nine patients (three men and six women with an average age of 57 years) presented with progressive neurologic deterioration while on medical therapy for large right hemispheric cerebral infarction. Clinical signs of uncal herniation (anisocoria or fixed and dilated pupils, and/or left hemiplegia...

journal_title：Stroke

authors： Delashaw JB,Broaddus WC,Kassell NF,Haley EC,Pendleton GA,Vollmer DG,Maggio WW,Grady MS

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the physical and, to a lesser extent, emotional outcome of stroke survivors has been well documented, there are far fewer data relating to the outcomes of those who care for them. We aimed to describe the outcome of those caring for stroke patients and to identify both patient and caregi...

journal_title：Stroke

authors： Dennis M,O'Rourke S,Lewis S,Sharpe M,Warlow C

更新日期：1998-09-01 00:00:00

abstract：:Background and Purpose- Hypertrophic cardiomyopathy patients with atrial fibrillation are at increased risk of stroke, and anticoagulation is strongly recommended. However, limited data are available regarding the safety and effectiveness of non-vitamin K antagonist oral anticoagulants (NOACs) for primary prevention o...

journal_title：Stroke

authors： Lee HJ,Kim HK,Jung JH,Han KD,Lee H,Park JB,Kim HM,Kim YJ,Ommen SR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Reduction of cerebral blood flow and vasomotor reactivity (VMR) are thought to play an important role in the pathogenesis of cerebral microangiopathy. The aim of our study was to determine whether near-infrared spectroscopy (NIRS) can detect a reduced VMR in patients with microangiopathy, whether...

journal_title：Stroke

authors： Terborg C,Gora F,Weiller C,Röther J

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The most powerful predictors of functional recovery and eventual home discharge among stroke survivors are the initial severity of the stroke and the patient's age. We analyzed a large population of stroke rehabilitation admissions by stratifying subgroups with coherent outcomes in an attempt to ...

journal_title：Stroke

authors： Alexander MP

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To investigate the incidence of retrograde flow from complex plaques (> or =4-mm-thick, ulcerated, or superimposed thrombi) of the descending aorta (DAo) and its potential role in embolic stroke. METHODS:Ninety-four consecutive acute stroke patients with aortic plaques > or =3-mm-thick in transe...

journal_title：Stroke

authors： Harloff A,Simon J,Brendecke S,Assefa D,Helbing T,Frydrychowicz A,Weber J,Olschewski M,Strecker C,Hennig J,Weiller C,Markl M

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The clinical syndrome of transient ischemic attacks is accompanied in a significant percentage of patients by brain lesions or neuroimaging abnormalities whose structural counterparts have not been defined. The objective of this study was to analyze, in an experimental model of short-term (< 25 m...

journal_title：Stroke

authors： Garcia JH,Liu KF,Ye ZR,Gutierrez JA

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:NINDS (National Institute of Neurological Disorders and Stroke)-SiGN (Stroke Genetics Network) is an international consortium of ischemic stroke studies that aims to generate high-quality phenotype data to identify the genetic basis of pathogenic stroke subtypes. This analysis characterizes the e...

journal_title：Stroke

authors： Ay H,Arsava EM,Andsberg G,Benner T,Brown RD Jr,Chapman SN,Cole JW,Delavaran H,Dichgans M,Engström G,Giralt-Steinhauer E,Grewal RP,Gwinn K,Jern C,Jimenez-Conde J,Jood K,Katsnelson M,Kissela B,Kittner SJ,Kleindorfer D

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Conventional diets may cause hyperglycemia in patients with neurological injuries. The purpose of this study was to examine the effect on the severity of cerebral infarction of replacing carbohydrates as the primary dietary source of nonprotein calories. METHODS:Sixty-nine Long-Evans rats were e...

journal_title：Stroke

authors： Robertson C,Goodman JC,Grossman RG,Claypool M,White A

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies of the cerebroprotective effects of selective brain cooling have failed to show amelioration of ischemic injury in the cerebral cortex. This study was designed to test the hypothesis that mild-to-moderate selective brain cooling initiated after the onset of global brain ischemia in rats p...

journal_title：Stroke

authors： Kuluz JW,Gregory GA,Yu AC,Chang Y

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The objectives of the present study were to: (1) noninvasively identify white matter reorganization and monitor its progress within 6 weeks after the onset of stroke; and (2) quantitatively investigate the effect of recombinant human erythropoietin treatment on this structural change using in viv...

journal_title：Stroke

authors： Li L,Jiang Q,Ding G,Zhang L,Zhang ZG,Li Q,Panda S,Kapke A,Lu M,Ewing JR,Chopp M

更新日期：2009-03-01 00:00:00

abstract：:Background and Purpose- Cerebral small vessel disease (SVD) is associated with increased stroke risk and poor stroke outcomes. We aimed to evaluate whether chronic SVD burden is associated with poor recruitment of collaterals in large-vessel occlusive stroke. Methods- Consecutive patients with middle cerebral artery o...

journal_title：Stroke

authors： Lin MP,Brott TG,Liebeskind DS,Meschia JF,Sam K,Gottesman RF

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Cerebral venous sinus thrombosis is rare and can be promoted by various conditions. We report the case of cerebral venous thrombosis in a patient using androgens. CASE DESCRIPTION:A 31-year-old man using androgens for bodybuilding was admitted for headache and vomiting. He had cerebral venous sinus thrombos...

journal_title：Stroke

authors： Jaillard AS,Hommel M,Mallaret M

更新日期：1994-01-01 00:00:00

abstract：:The relationship between normal aging and regional cerebral blood flow (rCBF) computed as initial slope index (ISI) by Fourier method was investigated in 105 right-handed healthy volunteers (132 measurements) by Xe-133 inhalation method, and age-matched normal values were calculated. Mean brain ISI values showed signi...

journal_title：Stroke

authors： Matsuda H,Maeda T,Yamada M,Gui LX,Tonami N,Hisada K

更新日期：1984-03-01 00:00:00

abstract：:Life table analysis is a powerful statistical tool that has become the preferred technique for studying both the natural history of and the effect of treatment on disease outcome. We have found only one report using life table analysis to study rehabilitation outcome after stroke. We assessed the recovery of both inde...

journal_title：Stroke

authors： Reding MJ,Potes E

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To test the role of fibrinolysis in stroke, we used a mouse model in which preformed 2.5- to 3-microm-diameter fibrin microemboli are injected into the cerebral circulation. The microemboli lodge in the downstream precapillary vasculature and are susceptible to fibrinolysis. METHODS:We injected ...

journal_title：Stroke

authors： Atochin DN,Murciano JC,Gürsoy-Ozdemir Y,Krasik T,Noda F,Ayata C,Dunn AK,Moskowitz MA,Huang PL,Muzykantov VR

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute ischemic stroke, the hypoperfused but viable tissue is the main therapeutic target. In clinical routine, time-to-peak (TTP) maps are frequently used to estimate the hemodynamic compromise and to calculate the mismatch volume. We evaluated the accuracy of TTP maps to identify penumbral fl...

journal_title：Stroke

authors： Sobesky J,Zaro Weber O,Lehnhardt FG,Hesselmann V,Thiel A,Dohmen C,Jacobs A,Neveling M,Heiss WD

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite its high prevalence in stroke survivors, there is little clinical research on bowel dysfunction in this population. This is the first randomized controlled trial to evaluate treatment of constipation and fecal incontinence in stroke survivors. METHODS:Stroke patients with constipation or...

journal_title：Stroke

authors： Harari D,Norton C,Lockwood L,Swift C

更新日期：2004-11-01 00:00:00

abstract：:Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...

journal_title：Stroke

authors： White RP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Accumulation of iron after intracerebral hemorrhage causes free radical formation and oxidative damage resulting in liquefaction. The aim of this study was the investigation of molecular mechanisms underlying estrogen-mediated neuroprotective effect against iron-induced brain injury in vivo. MET...

journal_title：Stroke

authors： Chen TY,Tsai KL,Lee TY,Chiueh CC,Lee WS,Hsu C

更新日期：2010-01-01 00:00:00