Characterization of muscarinic cholinergic receptors in human and dog cerebral arteries.

abstract：BACKGROUND AND PURPOSE:20% of ischemic stroke is in the posterior circulation, but there is little prospective data on early recurrent stroke risk and whether vertebrobasilar stenosis predicts a high recurrence risk. This natural history data are important as it is technically possible to stent such lesions. Contrast e...

journal_title：Stroke

authors： Gulli G,Khan S,Markus HS

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Approximately one fourth of stroke occur during sleep. Despite the clinical and radiological similarities between wake-up stroke (WUS) and non-WUS, the functional outcomes of WUS are largely unknown. METHODS:This retrospective analysis reviewed 2289 consecutive patients with acute ischemic strok...

journal_title：Stroke

authors： Kim BJ,Lee SH,Shin CW,Ryu WS,Kim CK,Yoon BW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Extracorporeal rheopheresis is a safe method to optimize hemorheology. Our aim was to determine whether treatment with extracorporeal rheopheresis in patients with acute ischemic hemispheric stroke improves cerebral perfusion as assessed with serial 99mTc-ethyl-cysteinate-dimer single-photon emis...

journal_title：Stroke

authors： Berrouschot J,Barthel H,Köster J,Hesse S,Rössler A,Knapp WH,Schneider D

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Methods of performing and reporting randomized clinical trials (RCTs) are available, but weaknesses still occur. For observational studies, methodology is less well described, and weaknesses are even more likely. In recent guidelines for patients with subarachnoid hemorrhage (SAH), 25% of treatme...

journal_title：Stroke

authors： van der Schaaf IC,Ruigrok YM,Rinkel GJ,Algra A,van Gijn J

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study was performed to determine the relation between distribution of atherosclerosis and risk factors in Japanese patients with atherothrombotic occlusion. METHODS:We studied 154 patients with atherothrombotic occlusion of the extracranial internal carotid artery (n = 75, ICA group)...

journal_title：Stroke

authors： Yasaka M,Yamaguchi T,Shichiri M

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is controversy about the optimal patient position for the detection of right-to-left shunt (RLS). The study was performed to investigate which patient position best detects RLS during contrast-enhanced transcranial Doppler. METHODS:We prospectively evaluated consecutive patients with ische...

journal_title：Stroke

authors： Agustin SJ,Yumul MP,Kalaw AJ,Teo BC,Eng J,Phua Z,Singh R,Gan RN,Venketasubramanian N

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transorbital sonography may help establish diagnosis of central retinal artery occlusion (CRAO). Next to Doppler sonographic proof of CRAO, an intra-arterial spot sign can be detected in some cases. We hypothesized that it reflects calcified components. It may be associated with embolization from...

journal_title：Stroke

authors： Nedelmann M,Graef M,Weinand F,Wassill KH,Kaps M,Lorenz B,Tanislav C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Downregulation of the tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN), is thought to be a novel neuroprotective strategy in ischemic stroke, but the underlying mechanisms remain unclear. In this study, we aimed to validate the use of PTEN regulation of gamma-amino...

journal_title：Stroke

authors： Liu B,Li L,Zhang Q,Chang N,Wang D,Shan Y,Li L,Wang H,Feng H,Zhang L,Brann DW,Wan Q

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Coronary artery bypass grafting (CABG) is a frequently performed surgical procedure that can be associated with neurological complications. Some studies have demonstrated that new focal brain lesions, detected by MRI, can develop after CABG. Furthermore, it has been suggested that the presence of...

journal_title：Stroke

authors： Restrepo L,Wityk RJ,Grega MA,Borowicz L Jr,Barker PB,Jacobs MA,Beauchamp NJ,Hillis AE,McKhann GM

更新日期：2002-12-01 00:00:00

abstract：:The effect of ischemia on catecholamine and 5-hydroxytryptamine (5-HT) levels in brain cortex was examined in the gerbil stroke model. Unilateral common carotid artery occlusion produced bilateral decrease in cortical dopamine levels in gerbils both symptomatic and asymptomatic of cerbral ischemia. The 5-HT progressiv...

journal_title：Stroke

authors： Welch KM,Chabi E,Buckingham J,Bergin B,Achar VS,Meyer JS

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Efforts to increase the availability and shorten the time delivery of intravenous thrombolysis in patients with acute ischemic stroke carry the potential for tissue plasminogen activator administration in patients with diseases other than stroke, that is, stroke mimics (SMs). We aimed to determin...

journal_title：Stroke

authors： Tsivgoulis G,Alexandrov AV,Chang J,Sharma VK,Hoover SL,Lao AY,Liu W,Stamboulis E,Alexandrov AW,Malkoff MD,Frey JL

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hemodynamic insult by bilateral common carotid artery ligation has been shown to induce aneurysmal remodeling at the basilar terminus in a rabbit model. To characterize critical hemodynamics that initiate this remodeling, we applied a novel hemodynamics-histology comapping technique. METHODS:Eig...

journal_title：Stroke

authors： Metaxa E,Tremmel M,Natarajan SK,Xiang J,Paluch RA,Mandelbaum M,Siddiqui AH,Kolega J,Mocco J,Meng H

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The mechanisms underlying smooth muscle relaxations of cerebral arteries in response to nitric oxide (NO) and cyclic GMP (cGMP) are still not completely understood. The present study was designed to determine the role of potassium channels in the relaxations to NO donors 3-morpholinosydnonimine (...

journal_title：Stroke

authors： Onoue H,Katusic ZS

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) lower serum cholesterol and decrease the incidence of stroke and cardiovascular disease. There is growing evidence that statins exert some of their beneficial effects independent of cholesterol lowering. Indeed, we...

journal_title：Stroke

authors： Amin-Hanjani S,Stagliano NE,Yamada M,Huang PL,Liao JK,Moskowitz MA

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been proposed that spin trap agents such as N:-t-butyl-phenylnitrone (PBN) may be useful as neuroprotective agents in the treatment of ischemia and stroke. However, to date, there is little information concerning the effectiveness of spin trap agents when administered in combination with t...

journal_title：Stroke

authors： Lapchak PA,Chapman DF,Zivin JA

更新日期：2001-01-01 00:00:00

abstract：:The morphologic description and measurements of endarterectomy specimens are usually believed to be accurate and are used as the gold standard against which the findings of diagnostic procedures are judged. Pathology data on 289 endarterectomy specimens from five participating centers and the corresponding angiography...

journal_title：Stroke

authors： Schenk EA,Bond MG,Aretz TH,Angelo JN,Choi HY,Rynalski T,Gustafson NF,Berson AS,Ricotta JJ,Goodison MW

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...

journal_title：Stroke

authors： Chen H,Hu CJ,He YY,Yang DI,Xu J,Hsu CY

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acute cocaine use has been temporally associated with aneurysmal subarachnoid hemorrhage (aSAH). This study analyzes the impact of cocaine use on patient presentation, complications, and outcomes. METHODS:Data of patients admitted with aSAH between 1991 and 2009 were reviewed to determine impact...

journal_title：Stroke

authors： Chang TR,Kowalski RG,Caserta F,Carhuapoma JR,Tamargo RJ,Naval NS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The ability of therapeutic exercise after stroke to improve daily functioning and quality of life (QOL) remains controversial. We examined treatment effects on these outcomes in a randomized controlled trial (RCT) of exercise in subacute stroke survivors. METHODS:This is a secondary analysis of ...

journal_title：Stroke

authors： Studenski S,Duncan PW,Perera S,Reker D,Lai SM,Richards L

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke symptoms in the absence of recognized stroke are common, but potential associated dysfunctions have not been described. METHODS:We assessed quality-of-life measures using the Physical and Mental Component Summary scores of the Short Form 12 (PCS-12 and MCS-12) in the REasons for Geographi...

journal_title：Stroke

authors： Howard G,Safford MM,Meschia JF,Moy CS,Howard VJ,Pulley L,Gomez CR,Crowther M

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recent Icelandic studies have demonstrated linkage for common forms of stroke to chromosome 5q12 and association between phosphodiesterase4D (PDE4D) and ischemic stroke. Using a candidate region approach, we wanted to test the validity of these findings in a different population from northern Swe...

journal_title：Stroke

authors： Nilsson-Ardnor S,Wiklund PG,Lindgren P,Nilsson AK,Janunger T,Escher SA,Hallbeck B,Stegmayr B,Asplund K,Holmberg D

更新日期：2005-08-01 00:00:00

abstract：:Background and Purpose- Blood pressure (BP) variability may increase the risk of stroke and dementia. It remains inconclusive whether BP variability is associated with cerebral small vessel disease, a common and potentially devastating subclinical disease that contributes significantly to both stroke and dementia. Met...

journal_title：Stroke

authors： Ma Y,Song A,Viswanathan A,Blacker D,Vernooij MW,Hofman A,Papatheodorou S

更新日期：2020-01-01 00:00:00

abstract：:Background and Purpose- Many patients with acute ischemic stroke are not eligible for thrombolysis or mechanical reperfusion therapies due to contraindications, inaccessible vascular occlusions, late presentation, or large infarct core. Sphenopalatine ganglion (SPG) stimulation to enhance collateral flow and stabilize...

journal_title：Stroke

authors： Bornstein NM,Saver JL,Diener HC,Gorelick PB,Shuaib A,Solberg Y,Devlin T,Leung T,Molina CA,ImpACT-24A Investigators † .,ImpACT-24A Investigators include the Site Principal Investigators, DSMB members, and the Site Co-Investigators lis

更新日期：2019-05-23 00:00:00

abstract：BACKGROUND AND PURPOSE:Insular injuries are known to cause autonomic derangements. Patients with ruptured middle cerebral artery aneurysms frequently develop temporal hematomas (THs) in addition to subarachnoid hemorrhages, and those with TH may sustain autonomic derangements more frequently than those without TH. Hemi...

journal_title：Stroke

authors： Inamasu J,Sugimoto K,Watanabe E,Kato Y,Hirose Y

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about the clinical outcomes associated with posthemorrhage anticoagulation resumption for atrial fibrillation. This study had 2 objectives: first, to evaluate anticoagulation use after a first major bleed on warfarin or dabigatran and, second, to compare effectiveness and safety o...

journal_title：Stroke

authors： Hernandez I,Zhang Y,Brooks MM,Chin PK,Saba S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clinical trials have demonstrated improved 90-day outcomes for patients with acute ischemic stroke treated with stent retriever thrombectomy plus tissue-type plasminogen activator (SST+tPA) compared with tPA. Previous studies suggested that this strategy may be cost-effective, but models were der...

journal_title：Stroke

authors： Shireman TI,Wang K,Saver JL,Goyal M,Bonafé A,Diener HC,Levy EI,Pereira VM,Albers GW,Cognard C,Hacke W,Jansen O,Jovin TG,Mattle HP,Nogueira RG,Siddiqui AH,Yavagal DR,Devlin TG,Lopes DK,Reddy VK,du Mesnil de Rochemo

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:With the advent of time-dependent thrombolytic therapy for ischemic stroke, it has become increasingly important for stroke patients to arrive at the hospital quickly. This study investigates the association between the use of emergency medical services (EMS) and delay time among individuals with...

journal_title：Stroke

authors： Schroeder EB,Rosamond WD,Morris DL,Evenson KR,Hinn AR

更新日期：2000-11-01 00:00:00

abstract：:Many nonsteroidal anti-inflammatory drugs exert their effects by inhibiting the synthesis of prostanoids. More specifically, these agents block the synthesis of prostaglandin endoperoxide G2 from arachidonic acid by competing with arachidonate for binding to the cyclooxygenase active site of prostaglandin endoperoxide...

journal_title：Stroke

authors： Smith WL,DeWitt DL,Shimokawa T,Kraemer SA,Meade EA

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A high incidence of arteriovenous malformations (AVMs) is associated with hereditary hemorrhagic telangiectasia type 1. Endoglin, the gene mutated in this disorder, is expressed at reduced levels on blood vessels of these patients. Since endoglin is a component of the transforming growth factor-b...

journal_title：Stroke

authors： Matsubara S,Bourdeau A,terBrugge KG,Wallace C,Letarte M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The cause and clinical significance of residual dysplastic vessels after surgery for brain arteriovenous malformations (AVM) are unclear. We studied predictors and frequency of residual dysplastic vessels on cerebral angiography after AVM surgery. METHODS:The 240 prospectively enrolled surgical ...

journal_title：Stroke

authors： Stapf C,Connolly ES,Schumacher HC,Sciacca RR,Mast H,Pile-Spellman J,Mohr JP

更新日期：2002-04-01 00:00:00