Endogenous platelet activating factor does not modulate blood flow and metabolism in normal rat brain.

abstract：BACKGROUND AND PURPOSE:Stroke incidence and mortality are declining rapidly in developed countries. Little data on ethnic-specific stroke recurrence trends exist. Fourteen-year stroke recurrence trend estimates were evaluated in Mexican Americans and non-Hispanic whites in a population-based study. METHODS:Recurrent s...

journal_title：Stroke

authors： Sozener CB,Lisabeth LD,Shafie-Khorassani F,Kim S,Zahuranec DB,Brown DL,Skolarus LE,Burke JF,Kerber KA,Meurer WJ,Case E,Morgenstern LB

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To investigate differences between symptomatic and asymptomatic retinal embolism regarding the frequency and source of cerebral microemboli. METHODS:Thirty-seven patients with transient monocular blindness or retinal infarction and 27 patients (29 eyes) with asymptomatic retinal embolism were prospectively enr...

journal_title：Stroke

authors： Wijman CA,Gomes JA,Winter MR,Koleini B,Matjucha IC,Pochay VE,Babikian VL

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Enlarged perivascular spaces (EPVS) have been associated with aging, increased stroke risk, decreased cognitive function, and vascular dementia. However, the relationship of EPVS with age-related neuropathologies is not well understood. Therefore, the purpose of this study was to assess the neuro...

journal_title：Stroke

authors： Javierre-Petit C,Schneider JA,Kapasi A,Makkinejad N,Tamhane AA,Leurgans SE,Mehta RI,Barnes LL,Bennett DA,Arfanakis K

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral amyloid angiopathy (CAA) occasionally coexists with cerebral vasculitis. An immune system may influence deposition or degradation of the amyloid in cerebral blood vessels. The purpose of this study was to elucidate immune reactions associated with CAA. METHODS:In 11 elderly patients wit...

journal_title：Stroke

authors： Yamada M,Itoh Y,Shintaku M,Kawamura J,Jensson O,Thorsteinsson L,Suematsu N,Matsushita M,Otomo E

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Diffusion-weighted MRI (DWI) and perfusion-weighted MRI (PWI) are new techniques that can be used for the evaluation of acute ischemic stroke. However, their potential role in the management of patients treated with recombinant tissue plasminogen activator (rtPA) has yet to be determined. CASE DESCRIPTION:T...

journal_title：Stroke

authors： Lansberg MG,Tong DC,Norbash AM,Yenari MA,Moseley ME

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerated brain atrophy is described following ischemic stroke, but it is not known whether atrophy rates vary over the poststroke period. Examining rates of brain atrophy allows the identification o...

journal_title：Stroke

authors： Brodtmann A,Khlif MS,Egorova N,Veldsman M,Bird LJ,Werden E

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Maternal cigarette smoking increases the risk of neonatal morbidity. We tested the hypothesis that perinatal nicotine exposure causes heightened brain vulnerability to hypoxic-ischemic (HI) injury in neonatal rats through aberrant expression patterns of angiotensin II type 1 (AT(1)R) and type 2 (...

journal_title：Stroke

authors： Li Y,Xiao D,Dasgupta C,Xiong F,Tong W,Yang S,Zhang L

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Identification of acute ischemic stroke (AIS) cause is crucial for guidance of secondary prevention. Previous studies have yielded inconsistent results regarding possible correlations between AIS cause and thrombus composition, as assessed by semiquantitative histological analysis. Here, we perfo...

journal_title：Stroke

authors： Di Meglio L,Desilles JP,Solonomenjanahary M,Labreuche J,Ollivier V,Dupont S,Deschildre C,Maacha MB,Consoli A,Lapergue B,Piotin M,Blanc R,Ho-Tin-Noe B,Mazighi M,compoCLOT study group†.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is not known whether cerebral vasoprotective mechanisms in females include increased function of arterial K+ channels. We hypothesized that vasodilator responses mediated by activation of inwardly rectifying K+ (K(IR)) channels are greater in cerebral arteries of female versus male rats and th...

journal_title：Stroke

authors： Chrissobolis S,Sobey CG

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is scant population-based information on incidence and risk factors for ischemic stroke subtypes. METHODS:We identified all 454 residents of Rochester, Minn, with a first ischemic stroke between 1985 and 1989 from the Rochester Epidemiology Project medical records linkage system. We used S...

journal_title：Stroke

authors： Petty GW,Brown RD Jr,Whisnant JP,Sicks JD,O'Fallon WM,Wiebers DO

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to investigate whether the combination of blood flow measurements in the major cerebral arteries and measurements of cerebral metabolism can provide new insight into the hemodynamic effect of carotid lesions in patients with severe stenosis (> 70% reduction in diameter) of the internal ...

journal_title：Stroke

authors： van der Grond J,Eikelboom BC,Mali WP

更新日期：1996-11-01 00:00:00

abstract：:Before surgery, we evaluated major intracranial collateral pathways using transcranial Doppler ultrasonography (TCD) in 50 patients who then underwent carotid endarterectomy with concurrent multimodality cerebral monitoring. Patients were grouped with respect to collateral pathways demonstrated preoperatively by TCD: ...

journal_title：Stroke

authors： Schneider PA,Ringelstein EB,Rossman ME,Dilley RB,Sobel DF,Otis SM,Bernstein EF

更新日期：1988-11-01 00:00:00

abstract：:The morphologic description and measurements of endarterectomy specimens are usually believed to be accurate and are used as the gold standard against which the findings of diagnostic procedures are judged. Pathology data on 289 endarterectomy specimens from five participating centers and the corresponding angiography...

journal_title：Stroke

authors： Schenk EA,Bond MG,Aretz TH,Angelo JN,Choi HY,Rynalski T,Gustafson NF,Berson AS,Ricotta JJ,Goodison MW

更新日期：1988-03-01 00:00:00

abstract：:In a randomized pilot study we compared the efficacy of temporary anticoagulation with intravenous heparin sodium to the efficacy of aspirin in preventing cerebral infarction in hospitalized patients with recent (less than 7 days) transient ischemic attacks (TIAs). Fifty-five patients (33 men, 22 women) aged 36-81 (me...

journal_title：Stroke

authors： Biller J,Bruno A,Adams HP Jr,Godersky JC,Loftus CM,Mitchell VL,Banwart KJ,Jones MP

更新日期：1989-04-01 00:00:00

abstract：:Neurologic deficits that occur simultaneously with or subsequent to internal carotid artery occlusion may be influenced by the adequacy of the intracerebral collateral circulation. Transcranial Doppler ultrasonography was used to evaluate mean middle cerebral artery blood velocity and blood flow in major collateral ar...

journal_title：Stroke

authors： Schneider PA,Rossman ME,Bernstein EF,Torem S,Ringelstein EB,Otis SM

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several studies have reported on the correlation of ultrasonic carotid plaque morphology, cerebrovascular symptoms, and intraplaque hemorrhage. This study correlates ultrasonic carotid plaque morphology with the degree of carotid stenosis. METHODS:Carotid arteries (n=2460) were examined by using...

journal_title：Stroke

authors： AbuRahma AF,Wulu JT Jr,Crotty B

更新日期：2002-07-01 00:00:00

abstract：:We studied 1,273 patients with ischemic cerebral infarction who were entered into the Stroke Data Bank, a prospective, observational study involving four university hospitals and the Biometry and Field Studies Branch of the National Institute of Neurological Disorders and Stroke. Forty patients had noniatrogenic recur...

journal_title：Stroke

authors： Sacco RL,Foulkes MA,Mohr JP,Wolf PA,Hier DB,Price TR

更新日期：1989-08-01 00:00:00

abstract：:The gap between existing knowledge and the patient care provided in stroke has become more apparent. The translational gap is evidence of our scientific progress, but the sheer magnitude of our implementation gap is astounding. For instance, almost 5 decades ago we recognized the risk factors for stroke, yet in Canada...

journal_title：Stroke

authors： Hakim AM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It has been proposed that spin trap agents such as N:-t-butyl-phenylnitrone (PBN) may be useful as neuroprotective agents in the treatment of ischemia and stroke. However, to date, there is little information concerning the effectiveness of spin trap agents when administered in combination with t...

journal_title：Stroke

authors： Lapchak PA,Chapman DF,Zivin JA

更新日期：2001-01-01 00:00:00

abstract：:Blood flow velocity of the middle cerebral artery was monitored during cardiopulmonary bypass procedures by means of transcranial Doppler ultrasonography. Our investigation was carried out in a group of 16 patients with severe carotid stenosis or occlusion and in a control group of 42 patients with no or stenosis of l...

journal_title：Stroke

authors： von Reutern GM,Hetzel A,Birnbaum D,Schlosser V

更新日期：1988-06-01 00:00:00

abstract：:The author reviewed electrocardiographic records of 150 patients with acute stroke and 150 age- and sex-matched controls, to assess the relative frequencies of ECG abnormalities among the pathophysiologic categories of stroke, and to distinguish new abnormalities at the time of the stroke from those noted on prior tra...

journal_title：Stroke

authors： Goldstein DS

更新日期：1979-05-01 00:00:00

abstract：:It remains uncertain whether platelet activation in ischemic stroke is contributory or secondary to brain ischemia. The efficacy of aspirin (ASA) in stroke prevention suggests that platelet activation contributes to the occurrence of stroke. On the other hand, platelet activation may be simply a generalized consequenc...

journal_title：Stroke

authors： Shah AB,Beamer N,Coull BM

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid artery stenting (CAS) is an alternative to carotid endarterectomy (CEA) for stroke prevention. The value of this therapy relative to CEA remains uncertain. METHODS:In 10 958 Medicare patients aged 66 years or older between 2004 and 2006, we analyzed in-hospital, 1-year stroke, myocardial...

journal_title：Stroke

authors： Wang FW,Esterbrooks D,Kuo YF,Mooss A,Mohiuddin SM,Uretsky BF

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Do children have an increased risk for brain arteriovenous malformation (AVM) recurrence compared with adults and does this risk vary depending on initial presentation with AVM rupture? METHODS:We retrospectively studied 115 patients initially presenting with brain AVM under age 25 years who und...

journal_title：Stroke

authors： Copelan A,Drocton G,Caton MT,Smith ER,Cooke DL,Nelson J,Abla AA,Fox C,Amans MR,Dowd CF,Halbach VV,Higashida RT,Lawton MT,Kim H,Fullerton HJ,Gupta N,Hetts SW,UCSF Center For Cerebrovascular Research and UCSF Pediatric Br

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients. METHODS:Logistic regression was used to evaluate baseline characteristics and recan...

journal_title：Stroke

authors： Linfante I,Walker GR,Castonguay AC,Dabus G,Starosciak AK,Yoo AJ,Abou-Chebl A,Britz GW,Marden FA,Alvarez A,Gupta R,Sun CH,Martin C,Holloway WE,Mueller-Kronast N,English JD,Malisch TW,Bozorgchami H,Xavier A,Rai AT,F

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is a major healthcare problem in both the United States (US) and the United Kingdom (UK). Little comparative data are available concerning how generalist physicians in the two countries approach the management of patients at high risk of stroke. METHODS:Contemporaneous surveys of random s...

journal_title：Stroke

authors： Goldstein LB,Farmer A,Matchar DB

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Acceleration of healing mechanisms is a promising approach to improve current limitations of endovascular aneurysm therapy with the use of platinum coils. We evaluated a new endovascular therapeutic, bioabsorbable polymeric material (BPM), which may promote cellular reaction in the aneurysms. ME...

journal_title：Stroke

authors： Murayama Y,Viñuela F,Tateshima S,Gonzalez NR,Song JK,Mahdavieh H,Iruela-Arispe L

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endothelin receptor antagonists such as clazosentan decrease large-artery vasospasm after experimental and clinical subarachnoid hemorrhage. We used clazosentan to gain insight into the pathophysiology of subarachnoid hemorrhage by determining if decreasing vasospasm is associated with alleviatio...

journal_title：Stroke

authors： Sabri M,Ai J,Macdonald RL

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Arterial baroreflex is one of the most important mechanisms in the regulation of cardiovascular activities. Arterial baroreflex function can be expressed as baroreflex sensitivity (BRS). The present study was designed to test 2 hypotheses: (1) BRS is a new independent predictor for the incidence ...

journal_title：Stroke

authors： Liu AJ,Ma XJ,Shen FM,Liu JG,Chen H,Su DF

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to identify the most powerful binary measures of the treatment effect of tissue plasminogen activator (tPA) in the National Institute of Neurological Disorders and Stroke (NINDS) rTPA Stroke Trial. METHODS:Using the Classification and Regression Tree (CART) algorithm, we evaluated bina...

journal_title：Stroke

authors： Broderick JP,Lu M,Kothari R,Levine SR,Lyden PD,Haley EC,Brott TG,Grotta J,Tilley BC,Marler JR,Frankel M

更新日期：2000-10-01 00:00:00