Influence of gender on K+-induced cerebral vasodilatation.

abstract：:Using a scintillation camera system, hemispheric and regional cerebral blood flow was measured repeatedly during the course after a stroke. In 20 patients who improved clinically mean hemispheric and regional flow and relative weight of rapidly perfused compartment increased, while these values decreased in 15 patient...

journal_title：Stroke

authors： Heiss WD,Zeiler K,Turnheim M,Podreka I

更新日期：1976-07-01 00:00:00

abstract：:An anecdotal series of nine patients (three men and six women with an average age of 57 years) presented with progressive neurologic deterioration while on medical therapy for large right hemispheric cerebral infarction. Clinical signs of uncal herniation (anisocoria or fixed and dilated pupils, and/or left hemiplegia...

journal_title：Stroke

authors： Delashaw JB,Broaddus WC,Kassell NF,Haley EC,Pendleton GA,Vollmer DG,Maggio WW,Grady MS

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Zinc protoporphyrin (ZnPP) has multiple actions. It is an interleukin-1 antagonist as well as a hemeoxygenase inhibitor. Interleukin-1 is produced in ischemic brain and probably contributes to ischemic injury, although the role of heme oxygenase during ischemia is unknown. Whether ZnPP treatment ...

journal_title：Stroke

authors： Kadoya C,Domino EF,Yang GY,Stern JD,Betz AL

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recovery of patients within the first 6 months after stroke is well documented, but there has been little research on long-term recovery. The aim of this study was to analyze functional and motor recovery between admission to rehabilitation centres and 5 years after stroke. METHODS:This follow-u...

journal_title：Stroke

authors： Meyer S,Verheyden G,Brinkmann N,Dejaeger E,De Weerdt W,Feys H,Gantenbein AR,Jenni W,Laenen A,Lincoln N,Putman K,Schuback B,Schupp W,Thijs V,De Wit L

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of this study was to clarify whether mitral valve prolapse increases the subsequent risk of stroke. METHODS:A historical cohort study was conducted on 1079 residents of Olmsted County, Minnesota, who had an initial echocardiographic diagnosis of mitral valve prolapse between 1975 and...

journal_title：Stroke

authors： Orencia AJ,Petty GW,Khandheria BK,Annegers JF,Ballard DJ,Sicks JD,O'Fallon WM,Whisnant JP

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Coronary artery bypass grafting (CABG) is a frequently performed surgical procedure that can be associated with neurological complications. Some studies have demonstrated that new focal brain lesions, detected by MRI, can develop after CABG. Furthermore, it has been suggested that the presence of...

journal_title：Stroke

authors： Restrepo L,Wityk RJ,Grega MA,Borowicz L Jr,Barker PB,Jacobs MA,Beauchamp NJ,Hillis AE,McKhann GM

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To test the role of fibrinolysis in stroke, we used a mouse model in which preformed 2.5- to 3-microm-diameter fibrin microemboli are injected into the cerebral circulation. The microemboli lodge in the downstream precapillary vasculature and are susceptible to fibrinolysis. METHODS:We injected ...

journal_title：Stroke

authors： Atochin DN,Murciano JC,Gürsoy-Ozdemir Y,Krasik T,Noda F,Ayata C,Dunn AK,Moskowitz MA,Huang PL,Muzykantov VR

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with carotid occlusive disease and stage 2 cerebral hemodynamic failure, characterized by an increased oxygen extraction fraction (OEF) as measured by positron emission tomography (PET) and otherwise known as misery perfusion, have a high risk of cerebral ischemia and subsequent stroke. ...

journal_title：Stroke

authors： Imaizumi M,Kitagawa K,Hashikawa K,Oku N,Teratani T,Takasawa M,Yoshikawa T,Rishu P,Ohtsuki T,Hori M,Matsumoto M,Nishimura T

更新日期：2002-09-01 00:00:00

abstract：:To elucidate the connection between blood flow and the localized genesis and development of atherosclerosis and thrombosis at the human carotid artery bifurcation, detailed studies of the flow patterns and distributions of fluid velocity and wall shear rate in this region were carried out using a transparent segment o...

journal_title：Stroke

authors： Motomiya M,Karino T

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pial arterioles transiently dilate during cortical spreading depression (CSD), although the mechanisms are unclear. We tested the hypothesis that increased production of nitric oxide (NO) promotes arteriolar dilation. METHODS:Urethane-anesthetized rabbits were equipped with cranial windows, and ...

journal_title：Stroke

authors： Colonna DM,Meng W,Deal DD,Busija DW

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombin, heme oxygenase, complement, microglia activation, and leukocyte infiltration are all actively upregulated in intracerebral hemorrhage (ICH). Experimental evidence suggests that all these factors are involved in ICH-induced brain injury. This suggests a scenario whereby ICH actively (thr...

journal_title：Stroke

authors： Keep RF,Xi G,Hua Y,Hoff JT

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The importance of perioperative cognitive decline has long been debated. We recently demonstrated a significant correlation between perioperative cognitive decline and long-term cognitive dysfunction. Despite this association, some still question the importance of these changes in cognitive funct...

journal_title：Stroke

authors： Newman MF,Grocott HP,Mathew JP,White WD,Landolfo K,Reves JG,Laskowitz DT,Mark DB,Blumenthal JA,Neurologic Outcome Research Group and the Cardiothoracic Anesthesia Research Endeavors (CARE) Investigators of the Duke Heart Center.

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Cincinnati Prehospital Stroke Scale (CPSS) is recommended for emergency medical services use in identifying patients with stroke. Data evaluating its performance in the field are limited. We assessed the impact of training and use of the CPSS on the accuracy of paramedics' stroke patient iden...

journal_title：Stroke

authors： Frendl DM,Strauss DG,Underhill BK,Goldstein LB

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) have been used increasingly in recent years to evaluate acute stroke in the emergency setting. In the present study, we compared DWI and PWI findings in acute stroke patients with and without severe extracranial internal caroti...

journal_title：Stroke

authors： Neumann-Haefelin T,Wittsack HJ,Fink GR,Wenserski F,Li TQ,Seitz RJ,Siebler M,Mödder U,Freund HJ

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to evaluate how accurately length and volume of thrombotic clots occluding cerebral arteries of patients with acute ischemic stroke can be assessed from nonenhanced CT (NECT) scans reconstructed with different slice widths. METHODS:NECT image data of 58 patients with acute ischemic str...

journal_title：Stroke

authors： Riedel CH,Jensen U,Rohr A,Tietke M,Alfke K,Ulmer S,Jansen O

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The composition of carotid atherosclerosis was visualized by using 3D MRI at high resolution with 200-micrometer (3) voxels. Magnetic resonance signal characteristics were correlated with plaque components, including collagenous cap, necrotic core, and calcification, to define resolution and othe...

journal_title：Stroke

authors： Coombs BD,Rapp JH,Ursell PC,Reilly LM,Saloner D

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite its low efficacy, aspirin is the most widely used drug for secondary stroke prevention. The reasons why stroke recurs while patients are on aspirin are unknown. We have analyzed a series of patients who had recurrent strokes while on aspirin. METHODS:Out of 2231 consecutive patients who ...

journal_title：Stroke

authors： Bornstein NM,Karepov VG,Aronovich BD,Gorbulev AY,Treves TA,Korczyn AD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence suggests that the protease-activated receptor-1 (PAR-1), a thrombin receptor, mediates neuronal injury in experimental cerebral ischemia. The present study investigated whether PAR-1 plays a role in brain injury after global cerebral ischemia. METHODS:Adult male wild-type or PAR-1 knock...

journal_title：Stroke

authors： Wang J,Jin H,Hua Y,Keep RF,Xi G

更新日期：2012-09-01 00:00:00

abstract：:Stroke is a complex disease, with both genetic and environmental factors having a role in its pathogenesis. A review of past studies shows some evidence of genetic influences in the development of stroke. This is supported by studies of cardiovascular disease, which indicate major genetic influences at several levels ...

journal_title：Stroke

authors： Alberts MJ

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Pediatric National Institutes of Health Stroke Scale (PedNIHSS), an adaptation of the adult National Institutes of Health Stroke Scale, is a quantitative measure of stroke severity shown to be reliable when scored prospectively. The ability to calculate the PedNIHSS score retrospectively woul...

journal_title：Stroke

authors： Beslow LA,Kasner SE,Smith SE,Mullen MT,Kirschen MP,Bastian RA,Dowling MM,Lo W,Jordan LC,Bernard TJ,Friedman N,DeVeber G,Kirton A,Abraham L,Licht DJ,Jawad AF,Ellenberg JH,Lautenbach E,Ichord RN

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previously published meta-analyses exploring the effect of statins on stroke incidence included 20,000 patients and found a 2% to 30% risk reduction. It is not clear whether this is attributable to low-density lipoprotein-cholesterol (LDL-C) reduction. Statin trials have now included >90,000 pati...

journal_title：Stroke

authors： Amarenco P,Labreuche J,Lavallée P,Touboul PJ

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is unclear which harmonic imaging mode (power Doppler or gray-scale imaging) is superior and which measuring method is the most robust for the description of brain perfusion. METHODS:We performed an animal study on 6 beagles through the intact skull using a SONOS 5500 device and Optison injec...

journal_title：Stroke

authors： Seidel G,Algermissen C,Christoph A,Katzer T,Kaps M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although chemokines have been implicated in cardiovascular diseases, few studies have addressed the role of these inflammatory mediators in ischemic stroke. This study tested the hypothesis that RANTES (CCL5; regulated on activation, normal T-cell expressed and secreted) mediates the cerebral mic...

journal_title：Stroke

authors： Terao S,Yilmaz G,Stokes KY,Russell J,Ishikawa M,Kawase T,Granger DN

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In animals, drugs that increase brain amine concentrations influence the rate and degree of recovery from cortical lesions. It is therefore conceivable that antidepressants may influence outcome after ischemic brain injury in humans. We evaluated the effects of the norepinephrine reuptake blocker...

journal_title：Stroke

authors： Dam M,Tonin P,De Boni A,Pizzolato G,Casson S,Ermani M,Freo U,Piron L,Battistin L

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipophilic calcium channel antagonist flunarizine has been demonstrated to be neuroprotective in several models of cerebral ischemia. Ischemic spinal cord injury may have a similar pathophysiology and hence may respond in a similar fashion. This study was designed to investigate the effects o...

journal_title：Stroke

authors： Johnson SH,Kraimer JM,Graeber GM

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fish consumption has been postulated to reduce the risk of stroke. We conducted a dose-response meta-analysis to summarize the evidence from prospective studies regarding the association between fish consumption and stroke risk. METHODS:Pertinent studies were identified by searching Embase and P...

journal_title：Stroke

authors： Larsson SC,Orsini N

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We found age-related vulnerability to cerebral ischemia in the hippocampus and striatum in spontaneously hypertensive rats. Further study revealed that ischemia-induced release of hippocampal taurine, an inhibitory amino acid, was reduced by 40% in aged rats compared with adult rats, which sugges...

journal_title：Stroke

authors： Yao H,Ooboshi H,Ibayashi S,Uchimura H,Fujishima M

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:National Institutes of Health Stroke Scale (NIHSS) item profiles that were recently proposed and validated may prove useful for clinical prognostication and research studies. We aimed to validate the NIHSS item profiles in hyper-acute stroke patients who received thrombolysis treatment (tissue-ty...

journal_title：Stroke

authors： Abdul-Rahim AH,Fulton RL,Sucharew H,Kleindorfer D,Khatri P,Broderick JP,Lees KR,SITS-MOST Steering Committee.

更新日期：2015-10-01 00:00:00

abstract：:Experimental subarachnoid hemorrhage (SAH) was induced in baboons by repeated injections of autologous blood into cisterna chiasmatis and cisterna magna, a total of 14-33 ml being injected over 3-4 days. Cerebral blood flow (CBF; 133xenon clearance) and cerebral metabolic rate of oxygen (CMRO2) were measured before, a...

journal_title：Stroke

authors： Sahlin C,Delgado T,Owman C,Svendgaard NA

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...

journal_title：Stroke

authors： Brouwers HB,Battey TW,Musial HH,Ciura VA,Falcone GJ,Ayres AM,Vashkevich A,Schwab K,Viswanathan A,Anderson CD,Greenberg SM,Pomerantz SR,Ortiz CJ,Goldstein JN,Gonzalez RG,Rosand J,Romero JM

更新日期：2015-09-01 00:00:00