Transcranial Doppler ultrasonography during cardiopulmonary bypass in patients with severe carotid stenosis or occlusion.

abstract：BACKGROUND AND PURPOSE:Neonatal stroke is increasingly recognized with an estimated incidence of one in 4000 live births per year. Pathways involved in the pathophysiology of neonatal stroke are diverse and may include thrombosis and thrombolysis, vascular reactivity, and inflammation. METHODS:We compared frequencies ...

journal_title：Stroke

authors： Miller SP,Wu YW,Lee J,Lammer EJ,Iovannisci DM,Glidden DV,Bonifacio SL,Collins A,Shaw GM,Barkovich AJ,Ferriero DM

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial atherosclerosis is one of the main causes of stroke, and high-resolution magnetic resonance imaging provides useful imaging biomarkers related to the risk of ischemic events. This study aims to evaluate differences in histogram features between culprit and nonculprit intracranial ath...

journal_title：Stroke

authors： Shi Z,Li J,Zhao M,Peng W,Meddings Z,Jiang T,Liu Q,Teng Z,Lu J

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with stroke and transient ischemic attack (TIA) often have comparable comorbidities, but it is unclear whether they have similar rates of depression or antidepressant use. METHODS:This study was a secondary analysis of a prospective cohort registry that enrolled subjects from 2006 to 20...

journal_title：Stroke

authors： El Husseini N,Goldstein LB,Peterson ED,Zhao X,Pan W,Olson DM,Zimmer LO,Williams JW Jr,Bushnell C,Laskowitz DT

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Diffusion magnetic resonance imaging (MRI) can quantitatively detect focal ischemic injury within minutes of onset, and perfusion MRI can evaluate the brain's microcirculation. N-Methyl-D-aspartate (NMDA) antagonists and reperfusion can reduce lesion size in stroke models. We used diffusion and p...

journal_title：Stroke

authors： Minematsu K,Fisher M,Li L,Sotak CH

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the cause of stroke among patients with patent foramen ovale (PFO) may be due to paradoxical cerebral embolism (PCE), this mechanism is often difficult to prove. The aim of our study was to evaluate the association between brain imaging findings suggestive of embolism and PFO among ische...

journal_title：Stroke

authors： Steiner MM,Di Tullio MR,Rundek T,Gan R,Chen X,Liguori C,Brainin M,Homma S,Sacco RL

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Citicoline, a naturally occurring precursor of phosphatidylcholine, is neuroprotective and is currently being assessed in clinical trials. To evaluate potential synergistic neuroprotective effects of prolonged citicoline treatment and early N-methyl-D-aspartate (NMDA) antagonist therapy, suboptim...

journal_title：Stroke

authors： Onal MZ,Li F,Tatlisumak T,Locke KW,Sandage BW Jr,Fisher M

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathogenesis of periventricular hyperintensity (PVH) is still uncertain. We investigated the relationship between PVH and risk factors for cerebrovascular diseases, especially extracranial carotid artery stenosis (ECAS). METHODS:We studied PVH and ECAS in 323 subjects between 1991 and 1994. ...

journal_title：Stroke

authors： Adachi T,Takagi M,Hoshino H,Inafuku T

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our goal was to compare outcomes of patients with proximal middle cerebral artery occlusions treated with intravenous tissue plasminogen activator (tPA) with those of patients treated with stent-based thrombectomy (SBT). METHODS:Patients with proximal middle cerebral artery occlusions included i...

journal_title：Stroke

authors： Leker RR,Eichel R,Gomori JM,Ramirez de Noriega F,Ben-Hur T,Cohen JE

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is known that atherosclerosis does not involve both carotid arteries to the same extent. Pathological investigations have demonstrated that lesions develop in regions of low wall shear stress. The aims of the present study were to verify the degree of carotid atherosclerosis asymmetry in a pop...

journal_title：Stroke

authors： Gnasso A,Irace C,Carallo C,De Franceschi MS,Motti C,Mattioli PL,Pujia A

更新日期：1997-05-01 00:00:00

abstract：:Bay U 3405 is a novel thromboxane receptor blocker. The present investigations describe its effects on experimental canine and porcine cardiac damage. In anesthetized dogs, a coronary artery was occluded for 6 hours and reperfused for 30 minutes. Bay U 3405 was administered intravenously 15 minutes after occlusion (1 ...

journal_title：Stroke

authors： Fiedler VB,Seuter F,Perzborn E

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To clarify diagnostic entities in ischemic stroke we analyzed the relation between the severity of carotid atherosclerosis, coagulation parameters, lipoproteins, neurological status, and risk factors in 232 patients. METHODS:Duplex ultrasonography, computed tomography scan, and laboratory invest...

journal_title：Stroke

authors： Szirmai IG,Kamondi A,Magyar H,Juhász C

更新日期：1993-12-01 00:00:00

abstract：:Background and Purpose- The ESCAPE trial (The Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) was a multicentre, randomized controlled trial of endovascular thrombectomy versus standard care for patients with acute ischemic strok...

journal_title：Stroke

authors： Shamy MCF,Dewar B,Chevrier S,Wang CQ,Page S,Goyal M,Demchuk AM,Hill MD

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence suggests that the protease-activated receptor-1 (PAR-1), a thrombin receptor, mediates neuronal injury in experimental cerebral ischemia. The present study investigated whether PAR-1 plays a role in brain injury after global cerebral ischemia. METHODS:Adult male wild-type or PAR-1 knock...

journal_title：Stroke

authors： Wang J,Jin H,Hua Y,Keep RF,Xi G

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is increasing interest in defining stroke lesion volume thresholds to predict poststroke outcome. However, there is a paucity of data on factors that impact the association between critical infarct thresholds volume and outcome. We sought to determine whether lesion thresholds best predicti...

journal_title：Stroke

authors： Patti J,Helenius J,Puri AS,Henninger N

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The relationship between arterial recanalization, infarct size, and outcome in patients treated with intravenous thrombolytics remains unclear. Therefore, we aimed to determine the time course of recombinant tissue plasminogen activator (rtPA)-induced recanalization in patients with cardioembolic...

journal_title：Stroke

authors： Molina CA,Montaner J,Abilleira S,Arenillas JF,Ribó M,Huertas R,Romero F,Alvarez-Sabín J

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previously, we have shown that hyperthermia significantly increased neuronal damage after ischemic injury in a focal embolic model of stroke in rats. In the present study, we examined the effects of hyperthermia on the efficacy of thrombolytic therapy in this stroke model. METHODS:In part A, eff...

journal_title：Stroke

authors： Noor R,Wang CX,Shuaib A

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is little data regarding the cost of pediatric stroke care or the elements that contribute to these costs. We examined costs for poststroke care during the first year after diagnosis and compared these costs with the volume of the cerebral infarct and the level of neurological and functiona...

journal_title：Stroke

authors： Lo W,Zamel K,Ponnappa K,Allen A,Chisolm D,Tang M,Kerlin B,Yeates KO

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We obtained magnetization transfer imaging (MTI) scans from individuals with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (1) to investigate the presence, extent, and nature of pathology in white and gray matter outside proton density (PD)-v...

journal_title：Stroke

authors： Iannucci G,Dichgans M,Rovaris M,Brüning R,Gasser T,Giacomotti L,Yousry TA,Filippi M

更新日期：2001-03-01 00:00:00

abstract：:Perforating branches of the middle cerebral arteries (MCA) were examined on the forebrain hemispheres of fourteen human brains. It was noticed that their intracerebral segments arose from the MCA main trunk, and its terminal and collateral (cortical) branches. They terminated in certain parts of the basal ganglia and ...

journal_title：Stroke

authors： Marinkovic SV,Milisavljevic MM,Kovacevic MS,Stevic ZD

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcranial Doppler (TCD) and carotid duplex (CD) provide rapid and safe screening for stroke patients but are highly operator dependent. We explored the feasibility of telemedicine (TM)-guided TCD/CD administered by a health care provider inexperienced with ultrasound. METHODS:Dual video scree...

journal_title：Stroke

authors： Mikulik R,Alexandrov AV,Ribo M,Garami Z,Porche NA,Fulep E,Grotta JC,Wojner-Alexandrov AW,Choi JY

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The composition of carotid atherosclerosis was visualized by using 3D MRI at high resolution with 200-micrometer (3) voxels. Magnetic resonance signal characteristics were correlated with plaque components, including collagenous cap, necrotic core, and calcification, to define resolution and othe...

journal_title：Stroke

authors： Coombs BD,Rapp JH,Ursell PC,Reilly LM,Saloner D

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Proinflammatory cytokines including interleukin-6 (IL-6) are supposed to play a pivotal role in the development of atherosclerosis. A common polymorphism in the promoter of the IL-6 gene (IL-6 -174G>C) affects plasma IL-6 concentrations and has been suggested as a risk factor for cardiovascular d...

journal_title：Stroke

authors： Weger M,Steinbrugger I,Haas A,März W,El-Shabrawi Y,Weger W,Schmut O,Renner W

更新日期：2005-02-01 00:00:00

abstract：:Longitudinal stretch of the rabbit basilar artery produces local injury followed by prolonged circular constriction. After stretching and rapid release in vitro localized constrictions promptly occurred. This could be prevented by prior treatment with cyanide or calcium-free solution. Once produced, constrictions pers...

journal_title：Stroke

authors： Duckles SP,Bevan RD,Bevan JA

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although insulin resistance and hyperinsulinemia play a crucial role in the pathogenesis of atherosclerosis, little is known about their roles in ischemic stroke. The purpose of this study was to clarify whether insulin resistance and hyperinsulinemia are causative factors in the pathogenesis of ...

journal_title：Stroke

authors： Shinozaki K,Naritomi H,Shimizu T,Suzuki M,Ikebuchi M,Sawada T,Harano Y

更新日期：1996-01-01 00:00:00

abstract：:Mild hypothermia is an established neuroprotectant in the laboratory, showing remarkable and consistent effects across multiple laboratories and models of brain injury. At the clinical level, mild hypothermia has shown benefits in patients who have experienced cardiac arrest and in some pediatric populations experienc...

journal_title：Stroke

authors： Yenari MA,Hemmen TM

更新日期：2010-10-01 00:00:00

abstract：:Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a co...

journal_title：Stroke

authors： Dichgans M,Planas AM,Biessels GJ,van der Worp B,Sudlow C,Norrving B,Lees K,Mattle HP

更新日期：2016-07-01 00:00:00

abstract：:Seventy-four patients with hypertensive putaminal hemorrhage (HPH) were followed at least 6 months after treatment and estimated by ADL. They were graded according to the state of consciousness on admission. The grading consists of 6 grades: Grade 1, fully conscious; Grade 2, somnolent; Grade 3, stuporous; Grade 4, se...

journal_title：Stroke

authors： Waga S,Yamamoto Y

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To estimate the effect of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors ("statins") on stroke ris, we combined the data of the randomized, placebo-controlled, double-blind trials with HMG-CoA reductase inhibitors published so far. METHODS:The studies were identified using ...

journal_title：Stroke

authors： Blauw GJ,Lagaay AM,Smelt AH,Westendorp RG

更新日期：1997-05-01 00:00:00

abstract：:Choline concentration is rate limiting in the synthesis of acetylcholine. There is a negative arteriovenous difference for choline concentration across the brain, indicating the steady output of choline from this organ. Cerebral ischemia may increase extracellular choline concentration by interfering with its removal ...

journal_title：Stroke

authors： Scremin OU,Jenden DJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The significance of structural changes associated with cerebral small-vessel disease (SVD), including white matter lesions (WML), lacunes, and brain atrophy, to outcome from acute intracerebral hemorrhage is uncertain. We determined associations of computed tomographic radiological manifestations...

journal_title：Stroke

authors： Sato S,Delcourt C,Heeley E,Arima H,Zhang S,Al-Shahi Salman R,Stapf C,Woo D,Flaherty ML,Vagal A,Levi C,Davies L,Wang J,Robinson T,Lavados PM,Lindley RI,Chalmers J,Anderson CS,INTERACT2 Investigators.

更新日期：2016-03-01 00:00:00