Time course of tissue plasminogen activator-induced recanalization in acute cardioembolic stroke: a case-control study.

abstract：BACKGROUND AND PURPOSE:We designed a prospective sequential pretreatment and posttreatment MRI study to assess the relation between neuroimaging parameters and clinical outcome in patients treated with intravenous recombinant tissue-type plasminogen activator (rtPA). METHODS:Patients with symptoms of acute hemispheric...

journal_title：Stroke

authors： Nighoghossian N,Hermier M,Adeleine P,Derex L,Dugor JF,Philippeau F,Ylmaz H,Honnorat J,Dardel P,Berthezène Y,Froment JC,Trouillas P

更新日期：2003-02-01 00:00:00

abstract：:Background and Purpose- Carotid web (CW) is a rare form of focal fibromuscular dysplasia defined as an abnormal shelf-like projection of intimal fibrous tissue into the carotid bulb. It is theorized that CW leads to ischemic stroke secondary to blood flow stasis and subsequent embolization. The natural history and opt...

journal_title：Stroke

authors： Zhang AJ,Dhruv P,Choi P,Bakker C,Koffel J,Anderson D,Kim J,Jagadeesan B,Menon BK,Streib C

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Unstable atherosclerotic plaques are characterized by increased macrophages and reduced smooth muscle cells (SMCs) and collagen content. Endoglin, an accessory transforming growth factor-beta (TGFbeta) receptor, is a modulator of TGFbeta signaling recently found to be expressed on SMCs in atheros...

journal_title：Stroke

authors： Bot PT,Hoefer IE,Sluijter JP,van Vliet P,Smits AM,Lebrin F,Moll F,de Vries JP,Doevendans P,Piek JJ,Pasterkamp G,Goumans MJ

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Cerebral venous sinus thrombosis is rare and can be promoted by various conditions. We report the case of cerebral venous thrombosis in a patient using androgens. CASE DESCRIPTION:A 31-year-old man using androgens for bodybuilding was admitted for headache and vomiting. He had cerebral venous sinus thrombos...

journal_title：Stroke

authors： Jaillard AS,Hommel M,Mallaret M

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study was performed to determine the relation between distribution of atherosclerosis and risk factors in Japanese patients with atherothrombotic occlusion. METHODS:We studied 154 patients with atherothrombotic occlusion of the extracranial internal carotid artery (n = 75, ICA group)...

journal_title：Stroke

authors： Yasaka M,Yamaguchi T,Shichiri M

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage caused by cerebral aneurysm rupture remains a life-threatening emergency despite advances in treatment. However, the mechanisms underlying aneurysm initiation, progression, and rupture remain unclear. We developed a method to induce experimental cerebral aneurysms in rats,...

journal_title：Stroke

authors： Moriwaki T,Takagi Y,Sadamasa N,Aoki T,Nozaki K,Hashimoto N

更新日期：2006-03-01 00:00:00

abstract：:Background and Purpose- The purpose of this study was to assess recent trends in the admission and mortality rates for subarachnoid hemorrhage in Canada. Methods- This retrospective cross-sectional study was based on data retrieved from the Canadian Institute for Health Information for all patients diagnosed with suba...

journal_title：Stroke

authors： Chan V,Lindsay P,McQuiggan J,Zagorski B,Hill MD,O'Kelly C

更新日期：2018-11-21 00:00:00

abstract：BACKGROUND AND PURPOSE:Milk fat globule-EGF factor-8 (MFGE8) has been reported to be neuroprotective in ischemic stroke. However, the effects of MFGE8 in early brain injury after subarachnoid hemorrhage (SAH) have not been investigated. We investigated the role of MFGE8 in early brain injury and the potential mechanism...

journal_title：Stroke

authors： Liu F,Hu Q,Li B,Manaenko A,Chen Y,Tang J,Guo Z,Tang J,Zhang JH

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Futile recanalization after acute ischemic stroke occurs in almost half of the patients despite optimal angiographic results. Multimodal neuroimaging may help to improve patient's selection but is still dismissed by many interventionalists. Our aim was to evaluate the accuracy of each parameter o...

journal_title：Stroke

authors： Espinosa de Rueda M,Parrilla G,Manzano-Fernández S,García-Villalba B,Zamarro J,Hernández-Fernández F,Sánchez-Vizcaino C,Carreón E,Morales A,Moreno A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:White matter (WM) is less vulnerable to ischemia than gray matter. In ischemic stroke caused by acute large-vessel occlusion, successful recanalization might therefore sometimes selectively salvage the WM, leading to infarct patterns confined to gray matter. This study examines occurrence, determ...

journal_title：Stroke

authors： Kleine JF,Kaesmacher M,Wiestler B,Kaesmacher J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Tacrolimus, an immunosuppressant agent, has been shown to reduce tissue injury and leukocyte accumulation after transient ischemia. This study was designed to evaluate quantitatively the inhibitory effects of tacrolimus on leukocyte rolling and on subsequent leukocyte accumulation in vivo after t...

journal_title：Stroke

authors： Tsujikawa A,Ogura Y,Hiroshiba N,Miyamoto K,Kiryu J,Honda Y

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Decompressive surgery (hemicraniectomy) for life-threatening massive cerebral infarction represents a controversial issue in neurocritical care medicine. We report here the 30-day mortality and 6- and 12-month functional outcomes from the DESTINY trial. METHODS:DESTINY (ISRCTN01258591) is a pros...

journal_title：Stroke

authors： Jüttler E,Schwab S,Schmiedek P,Unterberg A,Hennerici M,Woitzik J,Witte S,Jenetzky E,Hacke W,DESTINY Study Group.

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is increasingly recognized as the single most important cause of disabling ischemic stroke in the elderly. We undertook an international survey to characterize the frequency of AF-associated stroke, methods of AF detection, and patient features. METHODS:Consecutive patie...

journal_title：Stroke

authors： Perera KS,Vanassche T,Bosch J,Swaminathan B,Mundl H,Giruparajah M,Barboza MA,O'Donnell MJ,Gomez-Schneider M,Hankey GJ,Yoon BW,Roxas A Jr,Lavallee P,Sargento-Freitas J,Shamalov N,Brouns R,Gagliardi RJ,Kasner SE,Pieroni

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Previous research has reported worse outcomes after stroke for women and for African Americans, but few prospective population-based studies have systematically examined demographic differences on long-term stroke outcomes. Race and gender differences in 1-year stroke outcomes were examined using...

journal_title：Stroke

authors： Roth DL,Haley WE,Clay OJ,Perkins M,Grant JS,Rhodes JD,Wadley VG,Kissela B,Howard G

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Virtual reality (VR) is a new promising computer-assisted technology to promote motor recovery in stroke patients. VR-induced neuroplasticity supporting locomotor recovery is not known. We investigated the effects of VR intervention on cortical reorganization and associated locomotor recovery in ...

journal_title：Stroke

authors： You SH,Jang SH,Kim YH,Hallett M,Ahn SH,Kwon YH,Kim JH,Lee MY

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We evaluated the impact of admission hyperglycemia (HG) on stroke outcome in relation to the timing of reperfusion in patients treated with tissue plasminogen activator (tPA). METHODS:We studied 138 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with...

journal_title：Stroke

authors： Alvarez-Sabín J,Molina CA,Ribó M,Arenillas JF,Montaner J,Huertas R,Santamarina E,Rubiera M

更新日期：2004-11-01 00:00:00

abstract：:Background and Purpose- More intensive secondary prevention with newer drugs may be cost-effective in patients with coronary artery disease (CAD). Whether some subgroups of patients who had a transient ischemic attack (TIA) or ischemic stroke, but no prior CAD are at similar high risk of myocardial infarction as those...

journal_title：Stroke

authors： Boulanger M,Li L,Lyons S,Lovett NG,Kubiak MM,Silver L,Touzé E,Rothwell PM

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Posttraumatic stress disorder (PTSD) can be triggered by life-threatening medical events such as strokes and transient ischemic attacks (TIAs). Little is known regarding how PTSD triggered by medical events affects patients' adherence to medications. METHODS:We surveyed 535 participants, age ≥40...

journal_title：Stroke

authors： Kronish IM,Edmondson D,Goldfinger JZ,Fei K,Horowitz CR

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor inhibition has been hypothesized to provide neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models of a variety of compounds with varying selectivity for AMPA over other...

journal_title：Stroke

authors： Menniti FS,Buchan AM,Chenard BL,Critchett DJ,Ganong AH,Guanowsky V,Seymour PA,Welch WM

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High-dose human albumin (ALB) is robustly neuroprotective in rodent stroke models. A phase I dose-escalation study was conducted to assess the safety of ALB therapy in ischemic stroke. We analyzed the data for preliminary evidence of treatment efficacy. METHODS:Eighty-two subjects with acute isc...

journal_title：Stroke

authors： Palesch YY,Hill MD,Ryckborst KJ,Tamariz D,Ginsberg MD

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral small vessel disease reflected by white matter lesions (WMLs) in MRI and kidney function reflected by estimated glomerular filtration rate (eGFR) is closely associated in patients without stroke. We studied whether eGFR and WMLs predict long-term survival in patients with acute stroke. ...

journal_title：Stroke

authors： Oksala NK,Salonen T,Strandberg T,Oksala A,Pohjasvaara T,Kaste M,Karhunen PJ,Erkinjuntti T

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Traditional vascular risk factors do not completely explain the asymmetry, racial, and sex differences in carotid artery disease. Carotid anatomy and geometry may play a role in the pathogenesis of internal carotid artery (ICA) stenosis, but their effects are unknown. We hypothesized that carotid...

journal_title：Stroke

authors： Phan TG,Beare RJ,Jolley D,Das G,Ren M,Wong K,Chong W,Sinnott MD,Hilton JE,Srikanth V

更新日期：2012-06-01 00:00:00

abstract：:Longitudinal stretch of the rabbit basilar artery produces local injury followed by prolonged circular constriction. After stretching and rapid release in vitro localized constrictions promptly occurred. This could be prevented by prior treatment with cyanide or calcium-free solution. Once produced, constrictions pers...

journal_title：Stroke

authors： Duckles SP,Bevan RD,Bevan JA

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Leptin is the major adipose hormone that regulates body weight and energy expenditure by activating leptin receptors in the hypothalamus. Leptin receptors are also present in other cell types, and a potent antiapoptotic effect for leptin has recently been reported. We investigated whether leptin ...

journal_title：Stroke

authors： Zhang F,Wang S,Signore AP,Chen J

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Efforts at public education to improve adults' response to stroke symptoms continue to be disappointing, and very little has been developed to improve the knowledge base of children regarding brain attacks. Children may be able to exert a positive influence on adult behavior and to learn positive...

journal_title：Stroke

authors： Dressman LA,Hunter J

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Oxidative damage of mitochondrial DNA (mtDNA) in the ischemic brain is expected after ischemia/reperfusion injury. A recent study demonstrated limited patterns of mtDNA deletion in the brain after ischemia/reperfusion. We studied the ischemia/reperfusion-induced global changes of mtDNA integrity ...

journal_title：Stroke

authors： Chen H,Hu CJ,He YY,Yang DI,Xu J,Hsu CY

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pressure-flow relation has been characterized in normal cerebrum, but it has not been studied in cerebrum dependent on collateral flow. The purpose of this investigation was to examine the relation between systemic pressure, regional cerebral blood flow, and middle cerebral artery branch pres...

journal_title：Stroke

authors： Muhonen MG,Sawin PD,Loftus CM,Heistad DD

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Develop achievable benchmarks for 9 stroke performance measures (PM) and to identify organizational factors associated with adherence. METHODS:Adherence rates and achievable benchmarks were determined for 9 PM within a study of patients (n=2294) admitted with acute ischemic stroke at 17 hospital...

journal_title：Stroke

authors： Hinchey JA,Shephard T,Tonn ST,Ruthazer R,Selker HP,Kent DM

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Anticoagulation is a highly effective secondary prevention in patients with cardioembolic stroke and atrial fibrillation/flutter (AF). However, the condition remains underdiagnosed, because paroxysmal AF may be missed by diagnostic tests in the acute phase. In this study, the sensitivity of AF de...

journal_title：Stroke

authors： Kallmünzer B,Breuer L,Hering C,Raaz-Schrauder D,Kollmar R,Huttner HB,Schwab S,Köhrmann M

更新日期：2012-04-01 00:00:00

abstract：:It remains uncertain whether platelet activation in ischemic stroke is contributory or secondary to brain ischemia. The efficacy of aspirin (ASA) in stroke prevention suggests that platelet activation contributes to the occurrence of stroke. On the other hand, platelet activation may be simply a generalized consequenc...

journal_title：Stroke

authors： Shah AB,Beamer N,Coull BM

更新日期：1985-07-01 00:00:00