Increased expression of the transforming growth factor-beta signaling pathway, endoglin, and early growth response-1 in stable plaques.

abstract：BACKGROUND AND PURPOSE:Previously, we have shown that hyperthermia significantly increased neuronal damage after ischemic injury in a focal embolic model of stroke in rats. In the present study, we examined the effects of hyperthermia on the efficacy of thrombolytic therapy in this stroke model. METHODS:In part A, eff...

journal_title：Stroke

authors： Noor R,Wang CX,Shuaib A

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To elucidate how the motor pathways rewire the denervated tissue after stroke, we investigated remodeling of the corticospinal tract (CST) in transgenic mice with yellow fluorescent protein CST labeling in conjunction with transsynaptic pseudorabies virus retrograde tracing. METHODS:Adult male C...

journal_title：Stroke

authors： Liu Z,Zhang RL,Li Y,Cui Y,Chopp M

更新日期：2009-07-01 00:00:00

abstract：:Weights of matching right and left middle or posterior cerebral arteries and their main branches from the same animal were compared 8-10 weeks after unilateral denervation by superior cervical ganglionectomy. When compared in pairs, the denervated arterial systems weighed significantly less (mean 85%) than their inner...

journal_title：Stroke

authors： Bevan RD,Tsuru H,Bevan JA

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Language training success in chronic aphasia remains only moderate. Electric brain stimulation may be a viable way to enhance treatment efficacy. METHODS:In a randomized, double-blind, sham-controlled crossover trial, we assessed if anodal transcranial direct current stimulation compared to cath...

journal_title：Stroke

authors： Flöel A,Meinzer M,Kirstein R,Nijhof S,Deppe M,Knecht S,Breitenstein C

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite its high prevalence in stroke survivors, there is little clinical research on bowel dysfunction in this population. This is the first randomized controlled trial to evaluate treatment of constipation and fecal incontinence in stroke survivors. METHODS:Stroke patients with constipation or...

journal_title：Stroke

authors： Harari D,Norton C,Lockwood L,Swift C

更新日期：2004-11-01 00:00:00

abstract：:We reviewed demographic data on patients having 2,256 carotid endarterectomies in eight large hospitals in North Carolina to determine the frequency of blacks among these patients. Blacks comprised only 4.6% of the patients having carotid endarterectomy even though they comprised 26% of all patients discharged and 22%...

journal_title：Stroke

authors： Maxwell JG,Rutherford EJ,Covington D,Clancy TV,Tackett AD,Robinson N,Johnson G Jr

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Fever after aneurysmal subarachnoid hemorrhage is associated with poor outcome. Because hydrocephalus and extravasated blood may influence thermoregulation, we determined whether these factors increase the risk for fever after subarachnoid hemorrhage. METHODS:Fever within 14 days (subdivided int...

journal_title：Stroke

authors： Dorhout Mees SM,Luitse MJ,van den Bergh WM,Rinkel GJ

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Futile recanalization after acute ischemic stroke occurs in almost half of the patients despite optimal angiographic results. Multimodal neuroimaging may help to improve patient's selection but is still dismissed by many interventionalists. Our aim was to evaluate the accuracy of each parameter o...

journal_title：Stroke

authors： Espinosa de Rueda M,Parrilla G,Manzano-Fernández S,García-Villalba B,Zamarro J,Hernández-Fernández F,Sánchez-Vizcaino C,Carreón E,Morales A,Moreno A

更新日期：2015-09-01 00:00:00

abstract：:Regional cerebral blood flow (CBF) was measured (intra-arterial injections of 133Xe) and electroencephalograms (EEG) were recorded periodically before, for two hours during, and for one and one-fourth hours after middle cerebral artery (MCA) occlusion in 20 squirrel monkeys (Saimiri sciureus). A CBF-Paco2 response cur...

journal_title：Stroke

authors： Donley RF,Sundt TM,Anderson RE,Sharbrough FW

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:We report the clinical and neuroimaging findings of a patient who sustained multiple cerebral infarcts after the ingestion of concentrated hydrogen peroxide solution sold as a "health food" product. CASE DESCRIPTION:An 84-year-old man sustained focal neurological deficits immediately after ingesting 30 mL o...

journal_title：Stroke

authors： Sherman SJ,Boyer LV,Sibley WA

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There is scant information available on the incidence of transient ischemic attack (TIA) in a defined population. This study defines incidence rates of first TIA and subtypes of TIA during 1985-1989 and compares the incidence to that obtained from a 1960-1972 cohort study. METHODS:Medical record...

journal_title：Stroke

authors： Brown RD Jr,Petty GW,O'Fallon WM,Wiebers DO,Whisnant JP

更新日期：1998-10-01 00:00:00

abstract：:Neurogenically caused cardiac arrhythmias and their correlation to lesions within the central nervous system were examined prospectively in 54 patients with spontaneous intracerebral hemorrhage. All patients were examined neurologically daily for 3 weeks, with special attention given to signs of brainstem compression ...

journal_title：Stroke

authors： Stober T,Sen S,Anstätt T,Bette L

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intravenous thrombolysis for acute ischemic stroke is beneficial within 4.5 hours of symptom onset, but the effect rapidly decreases over time, necessitating quick diagnostic in-hospital work-up. Initial time strain occasionally results in treatment of patients with an alternate diagnosis (stroke...

journal_title：Stroke

authors： Zinkstok SM,Engelter ST,Gensicke H,Lyrer PA,Ringleb PA,Artto V,Putaala J,Haapaniemi E,Tatlisumak T,Chen Y,Leys D,Sarikaya H,Michel P,Odier C,Berrouschot J,Arnold M,Heldner MR,Zini A,Fioravanti V,Padjen V,Beslac-Bu

更新日期：2013-04-01 00:00:00

abstract：:Background and Purpose- Case reports suggest that unruptured intracranial aneurysms may serve as a nidus for thrombus formation and downstream embolic stroke. However, few data exist to support an association between unruptured aneurysms and ischemic stroke. Methods- We conducted a within-subjects case-control study o...

journal_title：Stroke

authors： Chen ML,Gupta A,Chatterjee A,Khazanova D,Dou E,Patel H,Gialdini G,Merkler AE,Navi BB,Kamel H

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is still unclear that impaired cerebrovascular reactivity (CVR) to acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron emission tomography (PET) in patients with occlusive carotid diseases. Therefore, in this study, the authors aimed to clarify whether OEF is e...

journal_title：Stroke

authors： Kuroda S,Shiga T,Houkin K,Ishikawa T,Katoh C,Tamaki N,Iwasaki Y

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The visual analogue scale is a self-reported, validated tool to measure quality of life (QoL). Our purpose was to determine whether baseline QoL predicted strokes in the ALLHAT study (Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial) and evaluate determinants of poststr...

journal_title：Stroke

authors： Shams T,Auchus AP,Oparil S,Wright CB,Wright J,Furlan AJ,Sila CA,Davis BR,Pressel S,Yamal JM,Einhorn PT,Lerner AJ,ALLHAT Collaborative Research Group.

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The first goal of this study was to determine the effect of glutamate on permeability and reactivity of the cerebral microcirculation. The second goal of this study was to determine a possible role for nitric oxide in the effects of glutamate on the cerebral microcirculation. METHODS:We examined...

journal_title：Stroke

authors： Mayhan WG,Didion SP

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Multiple acute ischemic lesions on diffusion-weighted magnetic resonance imaging (DWI-MRI) are thought to be of embolic origin. However, in several patients with multiple ischemic lesions on DWI-MRI, no embolic source was detected, despite a thorough clinical work-up. Stroke etiology in such case...

journal_title：Stroke

authors： Jauss M,Wessels T,Trittmacher S,Allendörfer J,Kaps M

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chronic ocular ischemia is a rare form of ischemia of the eye in patients with carotid artery occlusion (CAO). The early and often asymptomatic stage of chronic ocular ischemia is referred to as venous stasis retinopathy (VSR). The aim of this study was to gain insight into the prevalence, cause,...

journal_title：Stroke

authors： Klijn CJ,Kappelle LJ,van Schooneveld MJ,Hoppenreijs VP,Algra A,Tulleken CA,van Gijn J

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because the long-term security of endovascular treatments remains uncertain, a follow-up study of the patients treated in the International Subarachnoid Aneurysm Trial was performed to compare the frequency, timing, and consequences of aneurysm recurrence. METHODS:Patient data were reclassified ...

journal_title：Stroke

authors： Campi A,Ramzi N,Molyneux AJ,Summers PE,Kerr RS,Sneade M,Yarnold JA,Rischmiller J,Byrne JV

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To prevent new cardiovascular events after stroke, prescribed preventive drugs should be used continuously. This study measures persistent use of preventive drugs after stroke and identifies factors associated with persistence. METHODS:A 1-year cohort (21,077 survivors) from Riks-Stroke, the Swe...

journal_title：Stroke

authors： Glader EL,Sjölander M,Eriksson M,Lundberg M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Malignant cerebellar edema (MCE) is a life-threatening complication of acute ischemic stroke that requires timely diagnosis and management. Aim of this study was to identify imaging predictors in initial multiparametric computed tomography (CT), including whole-brain CT perfusion (WB-CTP). METHO...

journal_title：Stroke

authors： Fabritius MP,Thierfelder KM,Meinel FG,Othman AE,Dorn F,Sabel BO,Scheffler P,Ertl-Wagner B,Sommer WH,Kunz WG

更新日期：2017-09-01 00:00:00

abstract：:Background and Purpose- Intracerebral hemorrhage (ICH) has a poorer prognosis than acute ischemic stroke (AIS). However, clinician perception of prognosis may influence treatment decisions and adversely affect outcome. On acute CT, the conspicuity of ICH compared with AIS may lead clinicians to overestimate severity a...

journal_title：Stroke

authors： Tilling EJ,El Tawil S,Muir KW

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The modified Rankin Scale (mRS) is widely used to assess global outcome after stroke. The aim of the study was to examine rater variability in assessing functional outcomes using the conventional mRS, and to investigate whether use of a structured interview (mRS-SI) reduced this variability. MET...

journal_title：Stroke

authors： Wilson JT,Hareendran A,Hendry A,Potter J,Bone I,Muir KW

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Arterial baroreflex is one of the most important mechanisms in the regulation of cardiovascular activities. Arterial baroreflex function can be expressed as baroreflex sensitivity (BRS). The present study was designed to test 2 hypotheses: (1) BRS is a new independent predictor for the incidence ...

journal_title：Stroke

authors： Liu AJ,Ma XJ,Shen FM,Liu JG,Chen H,Su DF

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The reliability of the EuroQol and SF-36 questionnaires after stroke is not known. We therefore aimed to assess and compare the test-retest reliability of both instruments in a group of stroke patients. METHODS:A total of 2253 patients with stroke entered by United Kingdom hospitals in the Inter...

journal_title：Stroke

authors： Dorman P,Slattery J,Farrell B,Dennis M,Sandercock P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Platelet-rich thrombi are resistant to thrombolytics. Matrix metalloproteinases (MMPs) may be involved in platelet aggregation and contribute to thrombolysis failure in stroke patients. METHODS:Plasma samples from 23 stroke patients who had received thrombolytics and from 47 healthy volunteers w...

journal_title：Stroke

authors： Heo JH,Kim SH,Lee KY,Kim EH,Chu CK,Nam JM

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV(1)) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is no...

journal_title：Stroke

authors： Söderholm M,Zia E,Hedblad B,Engström G

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited small-artery disease that clinically involves only the brain. Particularly early in the disease, patients can show substantial or complete recovery after individual strokes. Cortic...

journal_title：Stroke

authors： Reddy H,De Stefano N,Mortilla M,Federico A,Matthews PM

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dichloroacetate facilitates a decrease in brain lactate during reperfusion after incomplete ischemia. This study examined the possible activation of pyruvate dehydrogenase enzyme by dichloroacetate to explain this effect. Because the duration of ischemia and hyperglycemia exacerbate ischemic brai...

journal_title：Stroke

authors： Dimlich RV,Nielsen MM

更新日期：1992-08-01 00:00:00