Arterial baroreflex: a novel target for preventing stroke in rat hypertension.

abstract：BACKGROUND AND PURPOSE:The objective of this study was to determine the clinical features, angiographic findings, and response to treatment with thrombolytic therapy in patients with ischemic stroke caused by acute occlusion of the distal internal carotid artery. METHODS:This is a retrospective case series from a pros...

journal_title：Stroke

authors： Zaidat OO,Suarez JI,Santillan C,Sunshine JL,Tarr RW,Paras VH,Selman WR,Landis DM

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To define desirable target low-density lipoprotein (LDL) cholesterol levels for the prevention of stroke recurrence, a post hoc analysis was performed in the J-STARS study (Japan Statin Treatment Against Recurrent Stroke). METHODS:Subjects (n=1578) were divided into groups based on mean value of...

journal_title：Stroke

authors： Hosomi N,Kitagawa K,Nagai Y,Nakagawa Y,Aoki S,Nezu T,Kagimura T,Maruyama H,Origasa H,Minematsu K,Uchiyama S,Matsumoto M,J-STARS Collaborators.

更新日期：2018-04-01 00:00:00

abstract：:The purpose of this work was to study the contractile activity of intracerebral microarterioles and their sensitivity to the calcium antagonist nimodipine. Potassium depolarization evoked contraction and rhythmic activity that was blocked by nimodipine (IC50 0.08 nM). High concentrations of noradrenaline and prostagla...

journal_title：Stroke

authors： Godfraind T,Morel N,Dessy C

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of this study is to assess whether the PHASES score allows to (1) match decisions taken by multidisciplinary team whether to observe or intervene, (2) classify patients being diagnosed with a ruptured versus unruptured intracranial aneurysm (UIA), and (3) discriminate patients at low risk...

journal_title：Stroke

authors： Bijlenga P,Gondar R,Schilling S,Morel S,Hirsch S,Cuony J,Corniola MV,Perren F,Rüfenacht D,Schaller K

更新日期：2017-08-01 00:00:00

abstract：:Background and Purpose- The ESCAPE trial (The Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) was a multicentre, randomized controlled trial of endovascular thrombectomy versus standard care for patients with acute ischemic strok...

journal_title：Stroke

authors： Shamy MCF,Dewar B,Chevrier S,Wang CQ,Page S,Goyal M,Demchuk AM,Hill MD

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Endovascular therapy has increasingly become the most common treatment for unruptured cerebral aneurysms in the United States. We evaluated a national, multi-hospital database to examine recent utilization trends and compare periprocedural outcomes between clipping and coiling treatments of unrup...

journal_title：Stroke

authors： McDonald JS,McDonald RJ,Fan J,Kallmes DF,Lanzino G,Cloft HJ

更新日期：2013-04-01 00:00:00

abstract：:The initial Stroke Therapy Academic Industry Roundtable (STAIR) recommendations published in 1999 were intended to improve the quality of preclinical studies of purported acute stroke therapies. Although recognized as reasonable, they have not been closely followed nor rigorously validated. Substantial advances have o...

journal_title：Stroke

authors： Fisher M,Feuerstein G,Howells DW,Hurn PD,Kent TA,Savitz SI,Lo EH,STAIR Group.

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Endovascular treatment of intracranial aneurysms is safe and effective but too often is followed by recurrences. Gene therapy may improve healing after embolization, and endovascular approaches may offer future in situ delivery systems designed to prevent aneurysm rupture. SUMMARY OF REVIEW:Advances in coil...

journal_title：Stroke

authors： Ribourtout E,Raymond J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Silent cerebrovascular disease (CVD) has been proposed as a predisposing condition for clinically overt stroke and vascular dementia. Recently, we found increased thrombin generation in silent CVD patients. Here, we report the effect of thrombin inhibition using a potent selective thrombin inhibi...

journal_title：Stroke

authors： Kario K,Matsuo T,Hoshide S,Umeda Y,Shimada K

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:After stroke, individuals have decreased mobility of the hemiparetic leg, which demands less muscle oxygen consumption; thus, blood flow decreases. The purpose of this study was to determine the effect of single limb exercise (SLE) on femoral artery blood flow, diameter, and peak flow velocity in...

journal_title：Stroke

authors： Billinger SA,Gajewski BJ,Guo LX,Kluding PM

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The clinical syndrome of transient ischemic attacks is accompanied in a significant percentage of patients by brain lesions or neuroimaging abnormalities whose structural counterparts have not been defined. The objective of this study was to analyze, in an experimental model of short-term (< 25 m...

journal_title：Stroke

authors： Garcia JH,Liu KF,Ye ZR,Gutierrez JA

更新日期：1997-11-01 00:00:00

abstract：:We used 44 splenectomized dogs to study the effects of isovolemic hemodilution with a crystalloid solution. The dogs were randomly divided into a hemodilution and a control group. In each group, 17 dogs were subjected to 6 hours of internal carotid and middle cerebral artery occlusion, and five dogs received sham oper...

journal_title：Stroke

authors： Hyodo A,Heros RC,Tu YK,Ogilvy C,Graichen R,Lagree K,Korosue K

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial cerebral atherosclerosis causes ischemic stroke in a significant number of patients. Technological advances over the past 10 years have enabled endovascular treatment of intracranial atherosclerotic stenosis. The number of patients treated with angioplasty or stent-assisted angioplas...

journal_title：Stroke

authors： Schumacher HC,Meyers PM,Higashida RT,Derdeyn CP,Lavine SD,Nesbit GM,Sacks D,Rasmussen P,Wechsler LR

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The modified Rankin Scale (mRS) is the recommended functional outcome assessment in stroke trials. Utility of mRS may be limited by interobserver variability. prestroke function, described using mRS, is often used as trial entry criterion. We assessed the reliability and validity of prestroke mRS...

journal_title：Stroke

authors： Fearon P,McArthur KS,Garrity K,Graham LJ,McGroarty G,Vincent S,Quinn TJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The current work is based on our previous finding that in neuronal cells, nmol/L concentrations of alpha-tocotrienol (TCT), but not alpha-tocopherol (TCP), blocked glutamate-induced death by suppressing early activation of c-Src kinase and 12-lipoxygenase. METHODS:The single neuron microinjectio...

journal_title：Stroke

authors： Khanna S,Roy S,Slivka A,Craft TK,Chaki S,Rink C,Notestine MA,DeVries AC,Parinandi NL,Sen CK

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several observations indicate that, during energy deprivation, endogenous dopamine may become neurotoxic. Accordingly, the nucleus striatum is a preferential site of silent infarcts in humans, and experimental ischemia caused by homolateral carotid occlusion selectively damages this dopamine-enri...

journal_title：Stroke

authors： Saulle E,Centonze D,Martín AB,Moratalla R,Bernardi G,Calabresi P

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The prevalence of constipation after stroke varies from 30% to 60%. The incidence of new-onset constipation during the early stage of stroke remains uncertain. The present study was designed to investigate the prevalence of new-onset constipation, its risk factors, and its impact on stroke outcom...

journal_title：Stroke

authors： Su Y,Zhang X,Zeng J,Pei Z,Cheung RT,Zhou QP,Ling L,Yu J,Tan J,Zhang Z

更新日期：2009-04-01 00:00:00

abstract：:Though unilateral blood distribution of the vertebral artery has not been studied in humans, it is significant when considering the ischemic events especially embolic occlusion in vertebrobasilar system. To clarify the blood distribution, Krypton-81m was continuously infused into the vertebral arteries of 10 patients....

journal_title：Stroke

authors： Taki W,Handa H,Higa T,Tanada S,Fukuyama H,Fujita T,Yonekawa Y,Kameyama M,Torizuka K

更新日期：1984-05-01 00:00:00

abstract：:Blood proteins could play a critical role in the pathogenesis of cerebral vasospasm in subarachnoid hemorrhage (SAH) as agonists and as antagonists of vasoconstriction. The present study was designed primarily to quantify the inhibition produced by antithrombin III of the phasic responses elicited by cumulative doses ...

journal_title：Stroke

authors： White RP

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolysis rates among minor stroke (MS) patients are increasing because of increased recognition of disability in this group and guideline changes regarding treatment indications. We examined the association of delays in door-to-needle (DTN) time with stroke severity. METHODS:We performed a r...

journal_title：Stroke

authors： Rostanski SK,Shahn Z,Elkind MSV,Liberman AL,Marshall RS,Stillman JI,Williams O,Willey JZ

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perioperative strokes (POS) are rare but serious complications for which mechanical thrombectomy could be beneficial. We aimed to compare the technical results and patients outcomes in a population of POS versus non-POS (nPOS) treated by mechanical thrombectomy. METHODS:From 2010 to 2017, 25 pat...

journal_title：Stroke

authors： Premat K,Clovet O,Frasca Polara G,Shotar E,Bartolini B,Yger M,Di Maria F,Baronnet F,Pistocchi S,Le Bouc R,Pires C,Sourour N,Alamowitch S,Samson Y,Degos V,Clarençon F

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral infarction in sickle cell disease is associated with arterial narrowing or occlusions of intracranial arteries. Primary stroke prevention would be feasible if a noninvasive screening test could be developed to detect intracranial disease in patients before symptoms develop. METHODS:To d...

journal_title：Stroke

authors： Adams RJ,Nichols FT,Figueroa R,McKie V,Lott T

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We investigated the effect of hypothermia induced 1 hour after transient (2-hour) middle cerebral artery occlusion on the extent of ischemic cell damage in the rat. METHODS:Middle cerebral artery occlusion was induced extracranially by insertion of a nylon filament into the right internal caroti...

journal_title：Stroke

authors： Zhang RL,Chopp M,Chen H,Garcia JH,Zhang ZG

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transtemporal insonation in transcranial Doppler sonography is often impaired by an insufficient signal-to-noise ratio, especially in elderly patients. A transpulmonary stable air microbubble suspension was injected intravenously in humans as an intracranial ultrasonic contrast agent. METHODS:In...

journal_title：Stroke

authors： Ries F,Honisch C,Lambertz M,Schlief R

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Astrocytes are potent regulators of brain capillary endothelial cell function. Recently, astrocytes were shown to regulate brain capillary endothelial expression of the fibrinolytic enzyme tissue plasminogen activator (tPA) and the anticoagulant thrombomodulin (TM). To study the mechanism of this...

journal_title：Stroke

authors： Tran ND,Correale J,Schreiber SS,Fisher M

更新日期：1999-08-01 00:00:00

abstract：:Functional assessment of animals following experimental cerebral ischemia is often difficult due to the passive nature of many neurologic exams. We attempted to increase the objectivity of motor function evaluation by adapting quantifiable behavioral tests and actively testing rats' motor capability following a cerebr...

journal_title：Stroke

authors： Combs DJ,D'Alecy LG

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intraventricular thrombolysis (IVT) is a promising treatment in facilitating intraventricular clot resolution after intraventricular hemorrhage. We examined in-hospital outcomes and resource utilization after thrombolysis in patients with intraventricular hemorrhage requiring ventriculostomy in a...

journal_title：Stroke

authors： Moradiya Y,Murthy SB,Newman-Toker DE,Hanley DF,Ziai WC

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Stroke PROTECT (Preventing Recurrence Of Thromboembolic Events through Coordinated Treatment) program systematically implements, at the time of acute transient ischemic attack (TIA) or ischemic stroke admission, 8 medication/behavioral secondary prevention measures known to improve outcome in...

journal_title：Stroke

authors： Ovbiagele B,Saver JL,Fredieu A,Suzuki S,Selco S,Rajajee V,McNair N,Razinia T,Kidwell CS

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clinical trials have demonstrated improved 90-day outcomes for patients with acute ischemic stroke treated with stent retriever thrombectomy plus tissue-type plasminogen activator (SST+tPA) compared with tPA. Previous studies suggested that this strategy may be cost-effective, but models were der...

journal_title：Stroke

authors： Shireman TI,Wang K,Saver JL,Goyal M,Bonafé A,Diener HC,Levy EI,Pereira VM,Albers GW,Cognard C,Hacke W,Jansen O,Jovin TG,Mattle HP,Nogueira RG,Siddiqui AH,Yavagal DR,Devlin TG,Lopes DK,Reddy VK,du Mesnil de Rochemo

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:High-sensitivity C-reactive protein (hsCRP), a marker of inflammation, is associated with atherosclerosis, hypertensive target organ damage, and cardiovascular events. In the general Japanese population, the level of hsCRP is reported to be lower than that in Western countries, and the relationsh...

journal_title：Stroke

authors： Ishikawa J,Tamura Y,Hoshide S,Eguchi K,Ishikawa S,Shimada K,Kario K

更新日期：2007-03-01 00:00:00