Short-term anomia training and electrical brain stimulation.

Abstract:

BACKGROUND AND PURPOSE:Language training success in chronic aphasia remains only moderate. Electric brain stimulation may be a viable way to enhance treatment efficacy. METHODS:In a randomized, double-blind, sham-controlled crossover trial, we assessed if anodal transcranial direct current stimulation compared to cathodal transcranial direct current stimulation and sham stimulation over the right temporo-parietal cortex would improve the success of short-term high-frequency anomia training. Twelve chronic poststroke aphasia patients were studied. Naming outcome was assessed after training and 2 weeks later. RESULTS:All training conditions led to a significant increase in naming ability, which was retained for at least 2 weeks after the end of the training. Application of anodal transcranial direct current stimulation significantly enhanced the overall training effect compared to sham stimulation. Baseline naming ability significantly predicted anodal transcranial direct current stimulation effects. CONCLUSIONS:Anodal transcranial direct current stimulation applied over the nonlanguage dominant hemisphere can enhance language training outcome in chronic aphasia. Clinical Trial Registration- URL: www.clinicaltrials.gov/. Unique identifier: NCT00822068.

journal_name

Stroke

journal_title

Stroke

authors

Flöel A,Meinzer M,Kirstein R,Nijhof S,Deppe M,Knecht S,Breitenstein C

doi

10.1161/STROKEAHA.110.609032

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

2065-7

issue

7

eissn

0039-2499

issn

1524-4628

pii

STROKEAHA.110.609032

journal_volume

42

pub_type

杂志文章,随机对照试验

相关文献

STROKE文献大全
  • Altered endothelial Ca2+ regulation after ischemia/reperfusion produces potentiated endothelium-derived hyperpolarizing factor-mediated dilations.

    abstract:BACKGROUND AND PURPOSE:Endothelium-derived hyperpolarizing factor (EDHF)-mediated dilations are potentiated after several pathologies, including ischemia/reperfusion (I/R). However, no study to date has addressed the mechanism by which this potentiation occurs. This study tested the hypothesis that potentiated EDHF-med...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.0000027439.61501.39

    authors: Marrelli SP

    更新日期:2002-09-01 00:00:00

  • Glutamate-induced cerebral vasodilation is mediated by nitric oxide through N-methyl-D-aspartate receptors.

    abstract:BACKGROUND AND PURPOSE:It was found that glutamate, a major neurotransmitter, is vasoactive in the cerebral circulation. However, the mechanism is unclear. This study was designed to investigate the role of nitric oxide (NO) and N-methyl-D-aspartate (NMDA) receptors in cerebral arteriolar dilation to glutamate. METHOD...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.26.5.857

    authors: Meng W,Tobin JR,Busija DW

    更新日期:1995-05-01 00:00:00

  • Posttraumatic stress disorder and adherence to medications in survivors of strokes and transient ischemic attacks.

    abstract:BACKGROUND AND PURPOSE:Posttraumatic stress disorder (PTSD) can be triggered by life-threatening medical events such as strokes and transient ischemic attacks (TIAs). Little is known regarding how PTSD triggered by medical events affects patients' adherence to medications. METHODS:We surveyed 535 participants, age ≥40...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.112.655209

    authors: Kronish IM,Edmondson D,Goldfinger JZ,Fei K,Horowitz CR

    更新日期:2012-08-01 00:00:00

  • In situ beta-irradiation of a brain arteriovenous malformation model.

    abstract:BACKGROUND AND PURPOSE:The treatment of large brain arteriovenous malformations (BAVMs) is challenging, and embolization alone is seldom curative. The study goal is to enhance the efficacy of arteriovenous malformation embolization by adding a beta-emitting isotope to the embolic agent. METHODS:The pig rete mirabile w...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000185673.73381.4c

    authors: Roy D,Soucy JP,Hartman NG,Janicki C,Weill A,Guilbert F,Papineau K,Raymond J

    更新日期:2005-11-01 00:00:00

  • Coronary and Basilar Artery Ectasia Are Associated: Results From an Autopsy Case-Control Study.

    abstract:BACKGROUND AND PURPOSE:Intracranial artery dolichoectasia (IADE) and coronary artery ectasia have been associated with stroke and myocardial infarction, respectively. Only rarely have cases of coexisting IADE and coronary artery ectasia been reported. We investigated this association in a large consecutive autopsy seri...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.010797

    authors: Pico F,Labreuche J,Hauw JJ,Seilhean D,Duyckaerts C,Amarenco P

    更新日期:2016-01-01 00:00:00

  • Early assessments of dysphagia and aspiration risk in acute stroke patients.

    abstract:BACKGROUND AND PURPOSE:Dysphagia is common after stroke and is a marker of poor prognosis. Early identification is important. This article reviews the merits and limitations of various assessment methods available to clinicians. METHODS:An electronic database search was performed of MEDLINE, EMBASE, and the Cochrane d...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.STR.0000066309.06490.B8

    authors: Ramsey DJ,Smithard DG,Kalra L

    更新日期:2003-05-01 00:00:00

  • Retrobulbar Spot Sign Predicts Thrombolytic Treatment Effects and Etiology in Central Retinal Artery Occlusion.

    abstract:BACKGROUND AND PURPOSE:Transorbital sonography may help establish diagnosis of central retinal artery occlusion (CRAO). Next to Doppler sonographic proof of CRAO, an intra-arterial spot sign can be detected in some cases. We hypothesized that it reflects calcified components. It may be associated with embolization from...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.009839

    authors: Nedelmann M,Graef M,Weinand F,Wassill KH,Kaps M,Lorenz B,Tanislav C

    更新日期:2015-08-01 00:00:00

  • Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY): a randomized, controlled trial.

    abstract:BACKGROUND AND PURPOSE:Decompressive surgery (hemicraniectomy) for life-threatening massive cerebral infarction represents a controversial issue in neurocritical care medicine. We report here the 30-day mortality and 6- and 12-month functional outcomes from the DESTINY trial. METHODS:DESTINY (ISRCTN01258591) is a pros...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/STROKEAHA.107.485649

    authors: Jüttler E,Schwab S,Schmiedek P,Unterberg A,Hennerici M,Woitzik J,Witte S,Jenetzky E,Hacke W,DESTINY Study Group.

    更新日期:2007-09-01 00:00:00

  • Flow patterns in the human carotid artery bifurcation.

    abstract::To elucidate the connection between blood flow and the localized genesis and development of atherosclerosis and thrombosis at the human carotid artery bifurcation, detailed studies of the flow patterns and distributions of fluid velocity and wall shear rate in this region were carried out using a transparent segment o...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.15.1.50

    authors: Motomiya M,Karino T

    更新日期:1984-01-01 00:00:00

  • Elevated tissue plasminogen activator antigen and stroke risk: The Stroke Prevention In Young Women Study.

    abstract:BACKGROUND AND PURPOSE:Abnormalities in endogenous fibrinolysis are associated with an increased risk for stroke in men and older adults. We tested the hypothesis that elevated plasma tissue plasminogen activator (tPA) antigen, a marker for impaired endogenous fibrinolysis, is an independent risk factor for stroke in y...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.1.7

    authors: Macko RF,Kittner SJ,Epstein A,Cox DK,Wozniak MA,Wityk RJ,Stern BJ,Sloan MA,Sherwin R,Price TR,McCarter RJ,Johnson CJ,Earley CJ,Buchholz DW,Stolley PD

    更新日期:1999-01-01 00:00:00

  • Efficacy of Stent-Retriever Thrombectomy in Magnetic Resonance Imaging Versus Computed Tomographic Perfusion-Selected Patients in SWIFT PRIME Trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stro

    abstract:BACKGROUND AND PURPOSE:The majority of patients enrolled in SWIFT PRIME trial (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke) had computed tomographic perfusion (CTP) imaging before randomization; 34 patients were randomized after magnetic resonance imaging...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/STROKEAHA.117.016669

    authors: Menjot de Champfleur N,Saver JL,Goyal M,Jahan R,Diener HC,Bonafe A,Levy EI,Pereira VM,Cognard C,Yavagal DR,Albers GW

    更新日期:2017-06-01 00:00:00

  • Effects of calcium channel blockers on neurologic outcome after focal ischemia in rabbits.

    abstract::To determine the efficacy of calcium channel blockers in preserving neurologic function after central nervous system ischemia, we studied three such agents in two animal models. We treated rabbits after inducing ischemia in the brain with intra-arterial microspheres and in the spinal cord using a removable aortic occl...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.19.8.1020

    authors: Lyden PD,Zivin JA,Kochhar A,Mazzarella V

    更新日期:1988-08-01 00:00:00

  • Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality.

    abstract:BACKGROUND AND PURPOSE:The aim of this study was to determine the 30-day mortality and morbidity of intracerebral hemorrhage in a large metropolitan population and to determine the most important predictors of 30-day outcome. METHODS:We reviewed the medical records and computed tomographic films for all cases of spont...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.7.987

    authors: Broderick JP,Brott TG,Duldner JE,Tomsick T,Huster G

    更新日期:1993-07-01 00:00:00

  • Long-term angiographic recurrences after selective endovascular treatment of aneurysms with detachable coils.

    abstract:BACKGROUND AND PURPOSE:Our aim in this study was to assess the incidence and determining factors of angiographic recurrences after endovascular treatment of aneurysms. METHODS:A retrospective analysis of all patients with selective endosaccular coil occlusion of intracranial aneurysms prospectively collected from 1992...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000073841.88563.E9

    authors: Raymond J,Guilbert F,Weill A,Georganos SA,Juravsky L,Lambert A,Lamoureux J,Chagnon M,Roy D

    更新日期:2003-06-01 00:00:00

  • Change in perfusion in acute nondominant hemisphere stroke may be better estimated by tests of hemispatial neglect than by the National Institutes of Health Stroke Scale.

    abstract:BACKGROUND AND PURPOSE:It has been reported that National Institutes of Health Stroke Scale (NIHSS) scores correlate poorly with hypoperfused tissue measured by perfusion-weighted imaging (PWI) in nondominant hemisphere stroke. We conducted 2 studies to determine whether tests of hemispatial neglect provide a better me...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/01.STR.0000089681.84041.69

    authors: Hillis AE,Wityk RJ,Barker PB,Ulatowski JA,Jacobs MA

    更新日期:2003-10-01 00:00:00

  • Rivaroxaban for stroke prevention in East Asian patients from the ROCKET AF trial.

    abstract:BACKGROUND AND PURPOSE:In Rivaroxaban Once Daily Oral Direct Factor Xa Inhibitor Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial, rivaroxaban was noninferior to dose-adjusted warfarin in preventing stroke or systemic embolism among patients with no...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1161/STROKEAHA.113.002968

    authors: Wong KS,Hu DY,Oomman A,Tan RS,Patel MR,Singer DE,Breithardt G,Mahaffey KW,Becker RC,Califf R,Fox KA,Berkowitz SD,Hacke W,Hankey GJ,Executive Steering Committee and the ROCKET AF Study Investigators.

    更新日期:2014-06-01 00:00:00

  • Intracranial Arterial Dolichoectasia and Stenosis: Risk Factors and Relation to Cerebral Small Vessel Disease.

    abstract:BACKGROUND AND PURPOSE:Intracranial arterial dolichoectasia (IADE) is a poorly understood arteriopathy compared with intracranial atherosclerotic stenosis (ICAS). We aimed to investigate the risk factors of IADE and ICAS and their relationship with neuroimaging markers of cerebral small vessel disease in a population-b...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.117.020130

    authors: Zhai FF,Yan S,Li ML,Han F,Wang Q,Zhou LX,Ni J,Yao M,Zhang SY,Cui LY,Jin ZY,Zhu YC

    更新日期:2018-05-01 00:00:00

  • Coronary artery disease and risk of major vascular events after cerebral infarction.

    abstract:BACKGROUND AND PURPOSE:The impact of asymptomatic coronary artery disease on the risk of major vascular events in patients with cerebral infarction is unknown. METHODS:Four hundred five patients with acute cerebral infarction underwent carotid, femoral artery, thoracic, and abdominal aorta ultrasound examination. Of 3...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.111.000142

    authors: Amarenco P,Lavallée PC,Labreuche J,Ducrocq G,Juliard JM,Feldman L,Cabrejo L,Meseguer E,Guidoux C,Adraï V,Ratani S,Kusmierek J,Lapergue B,Klein IF,Gongora-Rivera F,Jaramillo A,Abboud H,Olivot JM,Mazighi M,Touboul PJ

    更新日期:2013-06-01 00:00:00

  • Time course of tissue plasminogen activator-induced recanalization in acute cardioembolic stroke: a case-control study.

    abstract:BACKGROUND AND PURPOSE:The relationship between arterial recanalization, infarct size, and outcome in patients treated with intravenous thrombolytics remains unclear. Therefore, we aimed to determine the time course of recombinant tissue plasminogen activator (rtPA)-induced recanalization in patients with cardioembolic...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/hs1201.99821

    authors: Molina CA,Montaner J,Abilleira S,Arenillas JF,Ribó M,Huertas R,Romero F,Alvarez-Sabín J

    更新日期:2001-12-01 00:00:00

  • Computerized detection of cerebral emboli and discrimination from artifact using Doppler ultrasound.

    abstract:BACKGROUND AND PURPOSE:Transcranial Doppler ultrasound can detect circulating cerebral emboli. Monitoring of patients with potential embolic sources may allow identification of high-risk patients who can then be selected for prophylactic treatment. However, practical patient monitoring will require automated programs t...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.11.1667

    authors: Markus H,Loh A,Brown MM

    更新日期:1993-11-01 00:00:00

  • Arterial baroreflex: a novel target for preventing stroke in rat hypertension.

    abstract:BACKGROUND AND PURPOSE:Arterial baroreflex is one of the most important mechanisms in the regulation of cardiovascular activities. Arterial baroreflex function can be expressed as baroreflex sensitivity (BRS). The present study was designed to test 2 hypotheses: (1) BRS is a new independent predictor for the incidence ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.106.480061

    authors: Liu AJ,Ma XJ,Shen FM,Liu JG,Chen H,Su DF

    更新日期:2007-06-01 00:00:00

  • THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage.

    abstract:BACKGROUND AND PURPOSE:A ruptured intracranial aneurysm (IA) is the leading cause of a subarachnoid hemorrhage. This study seeks to define a specific gene whose mutation leads to disease. METHODS:More than 500 IA probands and 100 affected families were enrolled and clinically characterized. Whole exome sequencing was ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.014161

    authors: Santiago-Sim T,Fang X,Hennessy ML,Nalbach SV,DePalma SR,Lee MS,Greenway SC,McDonough B,Hergenroeder GW,Patek KJ,Colosimo SM,Qualmann KJ,Hagan JP,Milewicz DM,MacRae CA,Dymecki SM,Seidman CE,Seidman JG,Kim DH

    更新日期:2016-12-01 00:00:00

  • A comparison of long-term functional outcome after 2 middle cerebral artery occlusion models in rats.

    abstract:BACKGROUND AND PURPOSE:Proven behavioral assessment strategies for testing potential therapeutic agents in rat stroke models are needed. Few studies include tasks that demand higher levels of sensorimotor and cognitive function. Because behavioral outcome and rate of recovery vary among ischemia models, there is a need...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/hs1101.097397

    authors: Roof RL,Schielke GP,Ren X,Hall ED

    更新日期:2001-11-01 00:00:00

  • Reliability of the National Institutes of Health Stroke Scale. Extension to non-neurologists in the context of a clinical trial.

    abstract:BACKGROUND AND PURPOSE:The reliability of the National Institutes of Health Stroke Scale (NIHSS) has been established through testing its use in live and videotaped patients. This reliability testing has primarily focused on the use of the scale by neurologists. We sought to determine the reliability of the NIHSS as us...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.28.2.307

    authors: Goldstein LB,Samsa GP

    更新日期:1997-02-01 00:00:00

  • Level and value of circulating endothelial progenitor cells in patients after acute ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:Endothelial progenitor cells (EPCs) migrate from bone marrow to systemic circulation in response to tissue ischemia where they differentiate into mature endothelial cells for angiogenesis in situ. This study tested the hypothesis that the level of circulating EPCs is substantially increased and p...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.107.489401

    authors: Yip HK,Chang LT,Chang WN,Lu CH,Liou CW,Lan MY,Liu JS,Youssef AA,Chang HW

    更新日期:2008-01-01 00:00:00

  • Granulocyte adhesion, deformability, and superoxide formation in acute stroke.

    abstract:BACKGROUND AND PURPOSE:Impaired rheological properties of as well as cytotoxic substances produced by granulocytes may contribute to tissue damage in acute ischemic stroke. To assess changes in the properties of circulating granulocytes, we measured their adhesion, deformability, and superoxide generation in the first ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.23.1.33

    authors: Grau AJ,Berger E,Sung KL,Schmid-Schönbein GW

    更新日期:1992-01-01 00:00:00

  • Pressure-flow relations in canine collateral-dependent cerebrum.

    abstract:BACKGROUND AND PURPOSE:The pressure-flow relation has been characterized in normal cerebrum, but it has not been studied in cerebrum dependent on collateral flow. The purpose of this investigation was to examine the relation between systemic pressure, regional cerebral blood flow, and middle cerebral artery branch pres...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.23.7.988

    authors: Muhonen MG,Sawin PD,Loftus CM,Heistad DD

    更新日期:1992-07-01 00:00:00

  • The use of expected value as an aid to decisions regarding anticoagulation in patients with atrial fibrillation.

    abstract:BACKGROUND:The method described provides a rational means for determining whether to institute chronic anticoagulation to prevent stroke in patients with chronic atrial fibrillation under a variety of clinical circumstances. SUMMARY OF COMMENT:The concept of expected value is used in conjunction with data from clinica...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.12.2128

    authors: Nadeau SE

    更新日期:1993-12-01 00:00:00

  • Abnormal responses of the human cerebral microcirculation to papaverin during aneurysm surgery.

    abstract:BACKGROUND AND PURPOSE:The role of the cerebral microcirculation in delayed ischemia after subarachnoid hemorrhage remains obscure. To test the hypothesis that cerebral arterioles have a reduced capacity to dilate after subarachnoid hemorrhage, we studied the microvascular responses to papaverine (PPV) in patients unde...

    journal_title:Stroke

    pub_type: 信件

    doi:10.1161/STROKEAHA.108.522375

    authors: Pennings FA,Albrecht KW,Muizelaar JP,Schuurman PR,Bouma GJ

    更新日期:2009-01-01 00:00:00

  • Silencing of Long Noncoding RNA Nespas Aggravates Microglial Cell Death and Neuroinflammation in Ischemic Stroke.

    abstract::Background and Purpose- Ischemic stroke is one of the leading causes of morbidity and mortality worldwide and a major cause of long-term disability. Recently, long noncoding RNAs have been revealed, which are tightly associated with several human diseases. However, the functions of long noncoding RNAs in ischemic stro...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.023376

    authors: Deng Y,Chen D,Wang L,Gao F,Jin B,Lv H,Zhang G,Sun X,Liu L,Mo D,Ma N,Song L,Huo X,Yan T,Miao Z

    更新日期:2019-07-01 00:00:00