Volume of intracerebral hemorrhage. A powerful and easy-to-use predictor of 30-day mortality.

Abstract:

BACKGROUND AND PURPOSE:The aim of this study was to determine the 30-day mortality and morbidity of intracerebral hemorrhage in a large metropolitan population and to determine the most important predictors of 30-day outcome. METHODS:We reviewed the medical records and computed tomographic films for all cases of spontaneous intracerebral hemorrhage in Greater Cincinnati during 1988. Independent predictors of 30-day mortality were determined using univariate and multivariate statistical analyses. RESULTS:The 30-day mortality for the 188 cases of intracerebral hemorrhage was 44%, with half of deaths occurring within the first 2 days of onset. Volume of intracerebral hemorrhage was the strongest predictor of 30-day mortality for all locations of intracerebral hemorrhage. Using three categories of parenchymal hemorrhage volume (0 to 29 cm3, 30 to 60 cm3, and 61 cm3 or more), calculated by a quick and easy-to-use ellipsoid method, and two categories of the Glasgow Coma Scale (9 or more and 8 or less), 30-day mortality was predicted correctly with a sensitivity of 96% and a specificity of 98%. Patients with a parenchymal hemorrhage volume of 60 cm3 or more on their initial computed tomogram and a Glasgow Coma Scale score of 8 or less had a predicted 30-day mortality of 91%. Patients with a volume of less than 30 cm3 and a Glasgow Coma Scale score of 9 or more had a predicted 30-day mortality of 19%. Only one of the 71 patients with a volume of parenchymal hemorrhage of 30 cm3 or more could function independently at 30 days. CONCLUSIONS:Volume of intracerebral hemorrhage, in combination with the initial Glasgow Coma Scale score, is a powerful and easy-to-use predictor of 30-day mortality and morbidity in patients with spontaneous intracerebral hemorrhage.

journal_name

Stroke

journal_title

Stroke

authors

Broderick JP,Brott TG,Duldner JE,Tomsick T,Huster G

doi

10.1161/01.str.24.7.987

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

987-93

issue

7

eissn

0039-2499

issn

1524-4628

journal_volume

24

pub_type

杂志文章

相关文献

STROKE文献大全
  • Multicenter validation study of real-time ultrasonography, arteriography, and pathology: pathologic evaluation of carotid endarterectomy specimens.

    abstract::The morphologic description and measurements of endarterectomy specimens are usually believed to be accurate and are used as the gold standard against which the findings of diagnostic procedures are judged. Pathology data on 289 endarterectomy specimens from five participating centers and the corresponding angiography...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.19.3.289

    authors: Schenk EA,Bond MG,Aretz TH,Angelo JN,Choi HY,Rynalski T,Gustafson NF,Berson AS,Ricotta JJ,Goodison MW

    更新日期:1988-03-01 00:00:00

  • Evolution of diaschisis in a focal stroke model.

    abstract:BACKGROUND AND PURPOSE:Stroke produces diaschisis in adjacent and connected regions. The sequential changes in diaschisis over time and the relationship of regions of diaschisis to functional cortical areas and regions of poststroke neuroplasticity have not been determined. METHODS:Small cortical strokes were produced...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000117235.11156.55

    authors: Carmichael ST,Tatsukawa K,Katsman D,Tsuyuguchi N,Kornblum HI

    更新日期:2004-03-01 00:00:00

  • Cerebrovascular reserve in patients with carotid occlusive disease assessed by stable xenon-enhanced ct cerebral blood flow and transcranial Doppler.

    abstract:BACKGROUND AND PURPOSE:Cerebrovascular reserve (CVR) by both transcranial Doppler ultrasonography (TCD) and quantitative cerebral blood flow (CBF) can identify subgroups of patients at increased risk for stroke. A direct comparison of CVR measurements obtained with both technologies in patients with cerebrovascular occ...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/01.str.32.8.1811

    authors: Pindzola RR,Balzer JR,Nemoto EM,Goldstein S,Yonas H

    更新日期:2001-08-01 00:00:00

  • Cerebral microembolism and the risk of ischemia in asymptomatic high-grade internal carotid artery stenosis.

    abstract:BACKGROUND AND PURPOSE:Previous work has shown that cerebral microembolism detected with transcranial Doppler sonography distal to internal carotid artery stenosis occurs more frequently in recently symptomatic compared with asymptomatic patients. It has remained unclear whether cerebral microembolism also indicates a ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.26.11.2184

    authors: Siebler M,Nachtmann A,Sitzer M,Rose G,Kleinschmidt A,Rademacher J,Steinmetz H

    更新日期:1995-11-01 00:00:00

  • Endocrine Regulator rFGF21 (Recombinant Human Fibroblast Growth Factor 21) Improves Neurological Outcomes Following Focal Ischemic Stroke of Type 2 Diabetes Mellitus Male Mice.

    abstract::Background and Purpose- The complexity and heterogeneity of stroke, as well as the associated comorbidities, may render neuroprotective drugs less efficacious in clinical practice. Therefore, the development of targeted therapies to specific patient subsets has become a high priority in translational stroke research. ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.118.022119

    authors: Jiang Y,Liu N,Wang Q,Yu Z,Lin L,Yuan J,Guo S,Ahn BJ,Wang XJ,Li X,Lo EH,Sun X,Wang X

    更新日期:2018-12-01 00:00:00

  • Clinical Outcomes of Transplanted Modified Bone Marrow-Derived Mesenchymal Stem Cells in Stroke: A Phase 1/2a Study.

    abstract:BACKGROUND AND PURPOSE:Preclinical data suggest that cell-based therapies have the potential to improve stroke outcomes. METHODS:Eighteen patients with stable, chronic stroke were enrolled in a 2-year, open-label, single-arm study to evaluate the safety and clinical outcomes of surgical transplantation of modified bon...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.012995

    authors: Steinberg GK,Kondziolka D,Wechsler LR,Lunsford LD,Coburn ML,Billigen JB,Kim AS,Johnson JN,Bates D,King B,Case C,McGrogan M,Yankee EW,Schwartz NE

    更新日期:2016-07-01 00:00:00

  • Adiponectin and risk of stroke: prospective study and meta-analysis.

    abstract:BACKGROUND AND PURPOSE:The favorable cardiovascular effects attributed to adiponectin may lower risk of stroke. We investigated this in a prospective study and meta-analysis. METHODS:A case-cohort study nested within the Potsdam cohort of the European Prospective Investigation into Cancer was performed, with 170 incid...

    journal_title:Stroke

    pub_type: 杂志文章,meta分析

    doi:10.1161/STROKEAHA.113.001851

    authors: Arregui M,Buijsse B,Fritsche A,di Giuseppe R,Schulze MB,Westphal S,Isermann B,Boeing H,Weikert C

    更新日期:2014-01-01 00:00:00

  • Experimental acute thrombotic stroke in baboons.

    abstract::To study the effects of antithrombotic therapy in experimental stroke, we have characterized a baboon model of acute cerebrovascular thrombosis. In this model an inflatable silastic balloon cuff has been implanted by transorbital approach around the right middle cerebral artery (MCA), proximal to the take-off of the l...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.6.1254

    authors: Del Zoppo GJ,Copeland BR,Harker LA,Waltz TA,Zyroff J,Hanson SR,Battenberg E

    更新日期:1986-11-01 00:00:00

  • Behavioral risk factor prevalence and lifestyle change after stroke: a prospective study.

    abstract:BACKGROUND AND PURPOSE:Stroke patients have a 15-fold increased risk of recurrent stroke, and those with > or =1 risk factor have a further increased risk of recurrence. Previous work found management of physiological risk factors after stroke to be unsatisfactory, but there is little information on behavioral risks wi...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.31.8.1877

    authors: Redfern J,McKevitt C,Dundas R,Rudd AG,Wolfe CD

    更新日期:2000-08-01 00:00:00

  • Dietary Protein Intake and Stroke Risk in a General Japanese Population: The Hisayama Study.

    abstract:BACKGROUND AND PURPOSE:The influence of dietary protein intake on stroke risk is an area of interest. We investigated the association between dietary protein intake and stroke risk in Japanese, considering sources of protein. METHODS:A total of 2400 subjects aged 40 to 79 years were followed up for 19 years. Dietary p...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.016059

    authors: Ozawa M,Yoshida D,Hata J,Ohara T,Mukai N,Shibata M,Uchida K,Nagata M,Kitazono T,Kiyohara Y,Ninomiya T

    更新日期:2017-06-01 00:00:00

  • Third European Stroke Science Workshop.

    abstract::Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a co...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.013516

    authors: Dichgans M,Planas AM,Biessels GJ,van der Worp B,Sudlow C,Norrving B,Lees K,Mattle HP

    更新日期:2016-07-01 00:00:00

  • Ten-year prognosis of stroke and risk factors for death in a Japanese community: the Hisayama study.

    abstract:BACKGROUND AND PURPOSE:There have been very few population-based cohort studies of long-term prognosis and risk factors for death after stroke. We examined the 10-year prognosis, causes, and risk factors of death after stroke in a Japanese cohort. METHODS:During a 26-year follow-up of a cohort of 1621 subjects > or =4...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000091845.14833.43

    authors: Kiyohara Y,Kubo M,Kato I,Tanizaki Y,Tanaka K,Okubo K,Nakamura H,Iida M

    更新日期:2003-10-01 00:00:00

  • The influence of depression, social activity, and family stress on functional outcome after stroke.

    abstract:BACKGROUND AND PURPOSE:This study was designed to assess the quality of life after an active poststroke period of rehabilitation and to investigate the possibility of a return to a working environment for those still of working age. METHODS:The study was conducted on 180 consecutive patients affected by stroke who wer...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.24.10.1478

    authors: Angeleri F,Angeleri VA,Foschi N,Giaquinto S,Nolfe G

    更新日期:1993-10-01 00:00:00

  • Reperfusion in a gerbil model of forebrain ischemia using serial magnetic resonance FAIR perfusion imaging.

    abstract:BACKGROUND AND PURPOSE:Existing methods for the quantitative measurement of the changing cerebral blood flow (CBF) during reperfusion suffer from poor spatial or temporal resolution. The aim of this study was to implement a recently developed MRI technique for quantitative perfusion imaging in a gerbil model of reperfu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.6.1263

    authors: Pell GS,Lythgoe MF,Thomas DL,Calamante F,King MD,Gadian DG,Ordidge RJ

    更新日期:1999-06-01 00:00:00

  • Effect of BQ-123 and tissue plasminogen activator on vasospasm after subarachnoid hemorrhage in monkeys.

    abstract:BACKGROUND AND PURPOSE:We aimed to determine the effect of intracisternal administration of an endothelin-A receptor antagonist (BQ-123) against vasospasm in a monkey model and to determine whether this drug would have adverse interactions with intracisternal tissue plasminogen activator (TPA). METHODS:Thirty-three mo...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.27.9.1629

    authors: Kim CJ,Bassiouny M,Macdonald RL,Weir B,Johns LM

    更新日期:1996-09-01 00:00:00

  • Biosynthesis of leukotrienes in canine cerebral vasospasm.

    abstract::We produced cerebral vasospasm in 29 dogs by the "two-hemorrhage" method of intracisternal injections, 2 days apart, of autogenous arterial blood. Leukotriene (LT) C4, LTD4, and LTE4 were purified from incubated basilar artery, medulla oblongata, hypothalamus, median eminence, and blood clot from around the basilar ar...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.20.4.527

    authors: Yokota M,Tani E,Maeda Y

    更新日期:1989-04-01 00:00:00

  • Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults.

    abstract:BACKGROUND AND PURPOSE:The purpose of this study was to investigate whether the Framingham Cardiovascular Risk Profile and carotid artery intima-media thickness are associated with cortical volume and thickness. METHODS:Consecutive subjects participating in a prospective cohort study of aging and mild cognitive impair...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.112.659722

    authors: Cardenas VA,Reed B,Chao LL,Chui H,Sanossian N,DeCarli CC,Mack W,Kramer J,Hodis HN,Yan M,Buonocore MH,Carmichael O,Jagust WJ,Weiner MW

    更新日期:2012-11-01 00:00:00

  • Characterization of muscarinic cholinergic receptors in human and dog cerebral arteries.

    abstract::Various concentrations of acetylcholine (ACh) produced dose dependent relaxations of isolated, helical preparations of human cerebral arteries and these responses were blocked by atropine. The median effective concentration (EC50) of ACh was 6.1 +/- 0.2 X 10(-6)M. ACh produced dual responses in isolated dog cerebral a...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.17.2.300

    authors: Tsukahara T,Usui H,Taniguchi T,Shimohama S,Fujiwara M,Handa H

    更新日期:1986-03-01 00:00:00

  • Functional changes in human pial arteries (300 to 900 micrometer ID) within 48 hours of aneurysmal subarachnoid hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Animal studies of cerebral arteries 2 to 3 days after experimental subarachnoid hemorrhage (SAH) provide evidence of arterial change such as hyperresponsiveness to contractile agonists. There is evidence that small arteries, as well as those large enough to be seen on angiography, may be involved...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.29.12.2575

    authors: Bevan JA,Bevan RD,Walters CL,Wellman T

    更新日期:1998-12-01 00:00:00

  • Obesity increases risk of ischemic stroke in young adults.

    abstract:BACKGROUND AND PURPOSE:Body mass index has been associated with ischemic stroke in older populations, but its association with stroke in younger populations is not known. In light of the current obesity epidemic in the United States, the potential impact of obesity on stroke risk in young adults deserves attention. ME...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1161/STROKEAHA.115.008940

    authors: Mitchell AB,Cole JW,McArdle PF,Cheng YC,Ryan KA,Sparks MJ,Mitchell BD,Kittner SJ

    更新日期:2015-06-01 00:00:00

  • Care Received by Elderly US Stroke Survivors May Be Underestimated.

    abstract:BACKGROUND AND PURPOSE:Previous studies exploring stroke-related caregiving focused solely on informal caregiving and a relatively limited set of activities. We sought to determine whether, and at what cost, stroke survivors receive more care than matched controls using an expanded definition of caregiving and inclusio...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.012704

    authors: Skolarus LE,Freedman VA,Feng C,Wing JJ,Burke JF

    更新日期:2016-08-01 00:00:00

  • Coffee consumption and risk of stroke in women.

    abstract:BACKGROUND AND PURPOSE:Coffee consumption has been inconsistently associated with stroke incidence and mortality in previous studies. We investigated the association between coffee consumption and stroke incidence in the Swedish Mammography Cohort. METHODS:We prospectively followed of 34,670 women without a history of...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.603787

    authors: Larsson SC,Virtamo J,Wolk A

    更新日期:2011-04-01 00:00:00

  • Interrater agreement in evaluation of stroke patients with the unified neurological stroke scale.

    abstract:BACKGROUND:We sought to determine interrater agreement in evaluation of stroke patients with the Unified Form for Neurological Stroke Scales (UFNSS). SUMMARY OF REPORT:Fifty inpatients were independently examined by three neurologists. Kendall coefficients of concordance were computed for the different items of the UF...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.25.6.1263

    authors: Treves TA,Karepov VG,Aronovich BD,Gorbulev AY,Bornstein NM,Korczyn AD

    更新日期:1994-06-01 00:00:00

  • Vitamin D deficiency is associated with subclinical carotid atherosclerosis: the Northern Manhattan study.

    abstract:BACKGROUND AND PURPOSE:The purpose of this study was to assess the association of vitamin D deficiency and indices of mineral metabolism with subclinical carotid markers that predict cardiovascular events. METHODS:Two hundred three community-dwelling adults (Northern Manhattan Study; age, 68 ± 11; age range, 50 to 93 ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.608539

    authors: Carrelli AL,Walker MD,Lowe H,McMahon DJ,Rundek T,Sacco RL,Silverberg SJ

    更新日期:2011-08-01 00:00:00

  • Transient ischemic attack requiring hospitalization of children in the United States: kids' inpatient database 2003 to 2009.

    abstract:BACKGROUND AND PURPOSE:Transient ischemic attacks (TIA) are not well described in children. We assessed the prevalence of risk factors for TIA requiring hospitalization in children in a large national database. METHODS:Using the Healthcare Cost and Utilization Project Kids' Inpatient Database, children aged 1 to 18 ye...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.113.004526

    authors: Adil MM,Qureshi AI,Beslow LA,Jordan LC

    更新日期:2014-03-01 00:00:00

  • Eliciting information on differential sensation of heat in those with and without poststroke aphasia using a visual analogue scale.

    abstract:BACKGROUND AND PURPOSE:Aphasia can result in an inability to communicate the presence, location, or intensity of pain. Although visual analogue scales (VASs) exist, it is unknown whether they are useful in assessing pain in individuals with aphasia. The objective was to determine whether those with poststroke aphasia c...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000198872.75377.34

    authors: Korner-Bitensky N,Kehayia E,Tremblay N,Mazer B,Singer F,Tarasuk J

    更新日期:2006-02-01 00:00:00

  • 4G/4G genotype of PAI-1 gene is associated with reduced risk of stroke in elderly.

    abstract:BACKGROUND AND PURPOSE:Plasminogen activator inhibitor type 1 (PAI-1) is the main inhibitor of fibrinolysis, and high levels may increase the risk of cardiovascular disease. The 4G/5G polymorphism affects PAI-1 gene transcription with lower levels of plasma PAI-1 in the presence of the 5G allele. We investigated whethe...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000098004.26252.EB

    authors: Hoekstra T,Geleijnse JM,Kluft C,Giltay EJ,Kok FJ,Schouten EG

    更新日期:2003-12-01 00:00:00

  • Influence of weekend hospital admission on short-term mortality after intracerebral hemorrhage.

    abstract:BACKGROUND AND PURPOSE:There is expanding literature to show that certain patients admitted during the weekend have worse outcomes than similar patients admitted during the week. Although many clinicians have hypothesized the presence of this "weekend effect" with patients with intracerebral hemorrhage, there is a pauc...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.108.546572

    authors: Crowley RW,Yeoh HK,Stukenborg GJ,Medel R,Kassell NF,Dumont AS

    更新日期:2009-07-01 00:00:00

  • Ischemic stroke subtypes: a population-based study of incidence and risk factors.

    abstract:BACKGROUND AND PURPOSE:There is scant population-based information on incidence and risk factors for ischemic stroke subtypes. METHODS:We identified all 454 residents of Rochester, Minn, with a first ischemic stroke between 1985 and 1989 from the Rochester Epidemiology Project medical records linkage system. We used S...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.12.2513

    authors: Petty GW,Brown RD Jr,Whisnant JP,Sicks JD,O'Fallon WM,Wiebers DO

    更新日期:1999-12-01 00:00:00

  • Pediatric Stroke Belt: geographic variation in stroke mortality in US children.

    abstract:BACKGROUND AND PURPOSE:Numerous studies have demonstrated higher stroke mortality rates in adults residing in the Southeastern United States (the "Stroke Belt"). If the Stroke Belt is solely caused by regional differences in atherosclerotic stroke risk factors, it should not apply to children. METHODS:For the years 19...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000130514.21773.95

    authors: Fullerton HJ,Elkins JS,Johnston SC

    更新日期:2004-07-01 00:00:00