Abstract:
BACKGROUND AND PURPOSE:There have been very few population-based cohort studies of long-term prognosis and risk factors for death after stroke. We examined the 10-year prognosis, causes, and risk factors of death after stroke in a Japanese cohort. METHODS:During a 26-year follow-up of a cohort of 1621 subjects > or =40 years of age, 333 subjects developed first-ever stroke and were prospectively followed up for 10 years after onset. During these 10-year follow-up periods, 268 of the 333 stroke patients died. Of those, 239 (89.2%) underwent autopsy. RESULTS:The risk of death was greatest in the first year after first-stroke onset in both sexes (men, 40.3%; women, 43.7%). Thereafter, the survival curves decreased gradually, and risk of death reached 80.7% for men and 80.2% for women by the end of the 10-year follow-up. The 30-day case fatality rate was substantially greater in patients with cerebral hemorrhage (63.3%) or subarachnoid hemorrhage (58.6%) than in patients with cerebral infarction (9.0%). The risk of dying after the first stroke was twice the risk for stroke-free subjects. The most common cause of death was the index stroke in the first year. Thereafter, the impact of the first stroke gradually decreased, while that of recurrent stroke increased. Multivariate analysis revealed that age, lower body mass index, and hemorrhagic stroke were significant risk factors for death after stroke. CONCLUSIONS:Our findings suggest that the risk of death after first-ever stroke is high, in part because of the larger proportion of hemorrhagic stroke in Japanese relative to stroke victims in Western countries.
journal_name
Strokejournal_title
Strokeauthors
Kiyohara Y,Kubo M,Kato I,Tanizaki Y,Tanaka K,Okubo K,Nakamura H,Iida Mdoi
10.1161/01.STR.0000091845.14833.43subject
Has Abstractpub_date
2003-10-01 00:00:00pages
2343-7issue
10eissn
0039-2499issn
1524-4628pii
01.STR.0000091845.14833.43journal_volume
34pub_type
杂志文章相关文献
STROKE文献大全abstract:BACKGROUND AND PURPOSE:Interhospital transfer is a critical component in the treatment of acute anterior circulation large vessel occlusive stroke transferred for mechanical thrombectomy. Real-world data for benchmarking and theoretical modeling are limited. We sought to characterize transfer workflow from primary stro...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.117.017235
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Multiple acute ischemic lesions on diffusion-weighted magnetic resonance imaging (DWI-MRI) are thought to be of embolic origin. However, in several patients with multiple ischemic lesions on DWI-MRI, no embolic source was detected, despite a thorough clinical work-up. Stroke etiology in such case...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000231645.22128.ab
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT) pilot study showed that early intensive blood pressure-lowering can attenuate hematoma growth in acute intracerebral hemorrhage. The present analysis aimed to determine the treatment effects on hematoma growth by...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.112.651422
更新日期:2012-08-01 00:00:00
abstract::Non-invasive vascular testing has proven to be an effective means of identifying patients with significant extracranial carotid artery disease. Such tests can yield valuable physiologic data in patients with TIAs and can identify patients with soft signs who may have significant carotid artery disease and who may be c...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.11.4.325
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Motor dysfunction after unilateral deafferentation in primates can be overcome by restraining the unaffected limb. We asked whether a constraint-induced movement (CIM) program could be implemented within 2 weeks after stroke and whether CIM is more effective than traditional upper-extremity (UE) ...
journal_title:Stroke
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1161/01.str.31.12.2984
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Central nervous system serotonergic neurotransmission appears to play a role in mood disorders, eating habits, and sleep, and also modulates blood pressure and metabolism. This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.106.477638
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In the Asymptomatic Carotid Surgery Trial-1 (ACST-1), 3120 patients with tight asymptomatic carotid stenosis were randomly assigned to medical treatment alone or to carotid endarterectomy and appropriate medication. Successful carotid endarterectomy significantly reduced 10-year stroke risk in yo...
journal_title:Stroke
pub_type: 杂志文章,随机对照试验
doi:10.1161/STROKEAHA.111.000348
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A pulsatility index (PI) represents vascular resistance distal to an examined artery. The purpose of the present study was to evaluate an association between plasma total homocysteine (tHcy) and PIs of the cerebral arteries in patients with ischemic stroke. METHODS:Consecutive patients with isch...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.109.558403
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cerebral autoregulation may be impaired in the early days after subarachnoid hemorrhage (SAH). The purpose of this study was to examine the relationship between cerebral autoregulation and angiographic vasospasm (aVSP) and radiographic delayed cerebral ischemia (DCI) in patients with SAH. METHOD...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.113.002630
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Previous studies have demonstrated that echocardiographic left ventricular mass (LVM) is an independent risk factor for stroke in whites. Despite the greater burden of stroke, the echocardiographic predictors of stroke in African Americans remain poorly understood. METHODS:This investigation is ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000154893.68957.55
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although a genetic contribution to ischemic stroke is well recognized, only a handful of stroke loci have been identified by large-scale genetic association studies to date. Hypothesizing that genetic effects might be stronger for early- versus late-onset stroke, we conducted a 2-stage meta-analy...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.115.011328
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Choroid plexus (CP) secretes a cocktail of neurotrophic factors. In the present study, CP from neonatal pigs was encapsulated within alginate microcapsules for in vitro and in vivo neuroprotective studies. METHODS:In vitro studies involved serum deprivation of rat embryonic cortical neurons and ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000138954.25825.0b
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In Rivaroxaban Once Daily Oral Direct Factor Xa Inhibitor Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) trial, rivaroxaban was noninferior to dose-adjusted warfarin in preventing stroke or systemic embolism among patients with no...
journal_title:Stroke
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1161/STROKEAHA.113.002968
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In 2008, the Ministry of Health and Welfare of South Korea initiated the Regional Comprehensive Stroke Center (CSC) program to decrease the incidence and mortality of stroke nationwide. We evaluated the performance of acute ischemic stroke management after the Regional CSC program was introduced....
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.114.006134
更新日期:2014-08-01 00:00:00
abstract::To determine the incidence of perioperative silent cerebral infarction, 97 patients who underwent carotid endarterectomy were prospectively studied with preoperative and postoperative computed tomograms. Thirty-one of 96 patients (32%) had findings of cerebral infarction on preoperative computed tomograms. Silent cere...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.3.329
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Middle cerebral artery (MCA) stenosis is a relatively rare occlusive disease with an annual stroke risk of approximately 7% to 8%. However, the frequent coincidence of cardiac or ipsilateral carotid artery disease may lead to difficulties in identifying the relevant embolizing source in symptomat...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.27.8.1347
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Controlled multicenter studies have demonstrated the efficacy of systemic recombinant tissue-type plasminogen activator (rtPA) treatment in selected cases of acute ischemic stroke. The feasibility of this therapeutic option in clinical practice was assessed in a community-based approach. METHODS...
journal_title:Stroke
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1161/01.str.29.8.1544
更新日期:1998-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The onset of spontaneous intracerebral hemorrhage (ICH) is often accompanied by transient blood pressure (BP) elevation. The prognostic value and the determinants of this BP reaction have not entirely been solved, and the present study was focused on these questions. METHODS:From 1985 to 1991 in...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.28.7.1396
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Victims of air embolism often recover rapidly on hyperbaric treatment then deteriorate again, even if hyperbaric treatment is continued. In previous animal experiments, lidocaine has been shown to improve recovery of somatosensory evoked response amplitude after air embolism. However, animals in ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.10.1515
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Accumulation of endogenous guanidino-substituted analogues of L-arginine in chronic renal failure might contribute to some of the vascular and neurological disorders of this pathology. We tested the hypothesis that in human cerebral arteries, some guanidino compounds may increase vascular tone, t...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.30.10.2206
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Cilostazol, a phosphodiesterase 3' inhibitor, is used in Asia-Pacific countries for stroke prevention, but rarely used elsewhere. In addition to weak antiplatelet effects, it stabilizes endothelium, aids myelin repair and astrocyte-neuron energy transfer in laboratory models, effects that may be ...
journal_title:Stroke
pub_type: 杂志文章,meta分析
doi:10.1161/STROKEAHA.120.029454
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Several studies have reported poor outcomes in patients too good to treat with intravenous thrombolysis because of mild or rapidly improving symptoms. We sought to determine baseline clinical and imaging predictors of poor outcome in these patients. METHODS:Among 3950 consecutive stroke admissio...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.116.014871
更新日期:2016-12-01 00:00:00
abstract::Using the dexamethasone suppression test, we studied the activity of the hypothalamic-pituitary-adrenal axis within the first week after onset in 62 patients with acute ischemic stroke. Compared with two control groups (one comprising 25 elderly patients with various acute medical disorders and the other comprising 33...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.20.12.1685
更新日期:1989-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Perihematomal edema formation and consequent cell death contribute to the delayed brain injury evoked by intracerebral hemorrhage (ICH). We aimed to evaluate the effect of α7 nicotinic acetylcholine receptor (α7nAChR) stimulation on behavior, brain edema, and neuronal apoptosis. Furthermore, we a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.111.639989
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Identification of single-nucleotide polymorphisms (SNPs) associated with increased risk of new intracranial hemorrhage (ICH) after brain arteriovenous malformation (BAVM) diagnosis would facilitate risk stratification and identify potential targets for therapeutic intervention. METHODS:Patients ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000195133.98378.4b
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Our aim in this study was to assess the incidence and determining factors of angiographic recurrences after endovascular treatment of aneurysms. METHODS:A retrospective analysis of all patients with selective endosaccular coil occlusion of intracranial aneurysms prospectively collected from 1992...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.STR.0000073841.88563.E9
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this study is to report on the use of transcranial Doppler ultrasonography as a noninvasive diagnostic monitoring tool during local intra-arterial thrombolysis in a patient with acute embolic occlusion of the middle cerebral artery. CASE DESCRIPTION:We describe a 41-year-old woman wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.2.284
更新日期:1992-02-01 00:00:00
abstract::Background and Purpose- Lacunar strokes are subcortical infarcts with small size and high disability rates, largely due to injury of the corticospinal tract in the internal capsule (IC). Current rodent models of lacunar infarcts are created based on stereotactic coordinates. We tested the hypothesis that better unders...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.119.025646
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Embolic complications during ultrasound examinations are a rare cause of neurological deficits. The present case documents the occurrence of embolism by a nonobstructive compression maneuver during transcranial Doppler examination, resulting in a minor stroke. CASE DESCRIPTION:A 63-year-old man ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.25.5.1056
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation and high polypharmacy are unknown. METHODS:We used Medicare administrative data to evaluate patients with new atrial fibrillation diagnosis from 2015 to 2017, who initiated an oral anticoagulant with...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/STROKEAHA.120.029541
更新日期:2020-07-01 00:00:00