Detection of microembolic signals in patients with middle cerebral artery stenosis by means of a bigate probe. A pilot study.

Abstract:

BACKGROUND AND PURPOSE:Middle cerebral artery (MCA) stenosis is a relatively rare occlusive disease with an annual stroke risk of approximately 7% to 8%. However, the frequent coincidence of cardiac or ipsilateral carotid artery disease may lead to difficulties in identifying the relevant embolizing source in symptomatic patients. We undertook this study to evaluate the prevalence of microembolic signals (MES) as well as the potential and limitations of bigate monitoring in patients with MCA stenosis. METHODS:Fourteen patients aged 33 to 87 years with angiographically demonstrated symptomatic (acute, n = 2; chronic, n = 8) or asymptomatic (n = 4) MCA stenosis were examined. Six patients (43%) had additional cardiac (n = 3) or carotid artery (n = 3) disease. By means of a bigate probe, simultaneous insonation of prestenotic and poststenotic vessel segments was attempted. RESULTS:In 10 patients (71%), MES detection could be performed sufficiently at target vessel sites. In the remaining patients, either prestenotic (n = 3) or poststenotic (n = 1) monitoring was not satisfactory due to insufficient transtemporal bone window or the great length or extent of MCA stenosis. Poststenotic MES were detectable in 2 acutely symptomatic and 1 asymptomatic patient (prevalence, 21%). In the latter case, the sequential appearance of MES in both prestenotic and poststenotic channels excluded MCA stenosis but strongly favored coexisting carotid artery stenosis as the active embolic source. CONCLUSIONS:MES are detectable in patients with MCA stenosis. Bigate monitoring in this setting is feasible and allows identification of the active source among "competing" embolizing conditions.

journal_name

Stroke

journal_title

Stroke

authors

Nabavi DG,Georgiadis D,Mumme T,Zunker P,Ringelstein EB

doi

10.1161/01.str.27.8.1347

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

1347-9

issue

8

eissn

0039-2499

issn

1524-4628

journal_volume

27

pub_type

杂志文章

相关文献

STROKE文献大全
  • Minocycline-induced attenuation of iron overload and brain injury after experimental intracerebral hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Brain iron overload plays a detrimental role in brain injury after intracerebral hemorrhage (ICH). A recent study found that minocycline acts as an iron chelator and reduces iron-induced neuronal death in vitro. The present study investigated if minocycline reduces iron overload after ICH and iro...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.111.623926

    authors: Zhao F,Hua Y,He Y,Keep RF,Xi G

    更新日期:2011-12-01 00:00:00

  • PHASES Score for Prediction of Intracranial Aneurysm Growth.

    abstract:BACKGROUND AND PURPOSE:Growth of an intracranial aneurysm occurs in around 10% of patients at 2-year follow-up imaging and may be associated with aneurysm rupture. We investigated whether PHASES, a score providing absolute risks of aneurysm rupture based on 6 easily retrievable risk factors, also predicts aneurysm grow...

    journal_title:Stroke

    pub_type: 杂志文章,多中心研究

    doi:10.1161/STROKEAHA.114.008198

    authors: Backes D,Vergouwen MD,Tiel Groenestege AT,Bor AS,Velthuis BK,Greving JP,Algra A,Wermer MJ,van Walderveen MA,terBrugge KG,Agid R,Rinkel GJ

    更新日期:2015-05-01 00:00:00

  • Cerebral hemodynamic response to mental activation in normo- and hypercapnia.

    abstract::Changes of regional cerebral blood flow from rest to mental activation by a visually presented spatial reasoning test were measured during normo- and hypercapnia in 10 healthy subjects. Hypercapnia, elicited by inhalation of 6% CO2, resulted in similar flow increases in all 32 cortical regions measured. Increases of f...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.11.4.342

    authors: Maximilian VA,Prohovnik I,Risberg J

    更新日期:1980-07-01 00:00:00

  • Spontaneous improvement after acute ischemic stroke. A pilot study.

    abstract::Recent clinical studies emphasize the importance of early (less than 12 hours after onset) treatment of patients with acute ischemic stroke. Therapies have been proposed as being effective because of early clinical improvement. The frequency and degree of spontaneous improvement in such patients, however, is unknown. ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.21.7.1008

    authors: Biller J,Love BB,Marsh EE 3rd,Jones MP,Knepper LE,Jiang D,Adams HP Jr,Gordon DL

    更新日期:1990-07-01 00:00:00

  • Urgent carotid surgery and stenting may be safe after systemic thrombolysis for stroke.

    abstract:BACKGROUND AND PURPOSE:Early carotid surgery or stenting after thrombolytic treatment for stroke has become more common during recent years. It is unclear whether this carries an increased risk of postoperative complications and death. The aim of this nationwide population-based study was, therefore, to investigate the...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.113.003763

    authors: Koraen-Smith L,Troëng T,Björck M,Kragsterman B,Wahlgren CM,Swedish Vascular Registry and the Riks-Stroke Collaboration.

    更新日期:2014-03-01 00:00:00

  • Impaired endothelial function of forearm resistance arteries in CADASIL patients.

    abstract:BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary arteriopathy, which mainly involves the brain causing stroke and dementia. Mice expressing the mutated protein display early dysfunction in vasoreactivity in resistance arteries, b...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.107.490029

    authors: Stenborg A,Kalimo H,Viitanen M,Terent A,Lind L

    更新日期:2007-10-01 00:00:00

  • Methionine sulfoximine reduces cortical infarct size in rats after middle cerebral artery occlusion.

    abstract::The methionine analogue methionine sulfoximine was administered to 10 rats 24 hours before occlusion of the proximal left middle cerebral artery. Three days later the rats were decapitated and the brain infarct volumes were compared with those in 10 control rats that received saline before middle cerebral artery occlu...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.21.2.322

    authors: Swanson RA,Shiraishi K,Morton MT,Sharp FR

    更新日期:1990-02-01 00:00:00

  • Diurnal Variations in the First 24/7 Mobile Stroke Unit.

    abstract::Background and Purpose- Mobile Stroke Units (MSUs) provide innovative prehospital stroke care but their 24/7 operation has not been studied. Our study investigates 24/7 MSU diurnal variations related to transport frequency, patient characteristics, and stroke treatments. Methods- We compared transportation frequency, ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.119.024950

    authors: Zaidat OO,Changal KH,Sultan-Qurraie A,de Havenon A,Calderon VJ,Goins-Whitmore J,Patterson MS,Lin E

    更新日期:2019-07-01 00:00:00

  • Effects of a community-based intensive motor training program combined with early supported discharge after treatment in a comprehensive stroke unit: a randomized, controlled trial.

    abstract:BACKGROUND AND PURPOSE:Increased amount of therapy seems to be beneficial for motor recovery after stroke. The primary aim of the present study was to evaluate the effect of a 4-week community-based intensive motor training program combined with early supported discharge after initial treatment in a comprehensive strok...

    journal_title:Stroke

    pub_type: 杂志文章,随机对照试验

    doi:10.1161/STROKEAHA.110.584284

    authors: Askim T,Mørkved S,Engen A,Roos K,Aas T,Indredavik B

    更新日期:2010-08-01 00:00:00

  • Adeno-associated viral-vector-mediated hypoxia-inducible vascular endothelial growth factor gene expression attenuates ischemic brain injury after focal cerebral ischemia in mice.

    abstract:BACKGROUND AND PURPOSE:Exogenous delivery of vascular endothelial growth factor gene (VEGF) may provide a useful approach to the treatment of brain ischemia. We investigated the use of a hypoxia-responsive element to control VEGF expression given for neuroprotection. METHODS:Three groups (n=36) of mice received AAVH9-...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000240407.14765.e8

    authors: Shen F,Su H,Fan Y,Chen Y,Zhu Y,Liu W,Young WL,Yang GY

    更新日期:2006-10-01 00:00:00

  • Geographic variation in stroke risk in the United States. Region, urbanization, and hypertension in the Third National Health and Nutrition Examination Survey.

    abstract:BACKGROUND:In the United States, stroke mortality is higher in the south than in other regions. Hypertension is the main risk factor for stroke among older adults; however, few studies have examined group-specific regional and urbanization differences in hypertension prevalence. METHODS:Data from the Third National He...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.31.1.19

    authors: Obisesan TO,Vargas CM,Gillum RF

    更新日期:2000-01-01 00:00:00

  • Increased platelet activation in the chronic phase after cerebral ischemia and intracerebral hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Enhanced thromboxane (TX) biosynthesis has previously been reported in the acute phase after ischemic stroke. We investigated whether enhanced urinary excretion of 11-dehydro-TXB2, a noninvasive index of platelet activation, was present in the chronic phase after a transient ischemic attack (TIA)...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.30.3.546

    authors: van Kooten F,Ciabattoni G,Koudstaal PJ,Dippel DW,Patrono C

    更新日期:1999-03-01 00:00:00

  • Prognostic value and determinants of first-day mean arterial pressure in spontaneous supratentorial intracerebral hemorrhage.

    abstract:BACKGROUND AND PURPOSE:The onset of spontaneous intracerebral hemorrhage (ICH) is often accompanied by transient blood pressure (BP) elevation. The prognostic value and the determinants of this BP reaction have not entirely been solved, and the present study was focused on these questions. METHODS:From 1985 to 1991 in...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.28.7.1396

    authors: Fogelholm R,Avikainen S,Murros K

    更新日期:1997-07-01 00:00:00

  • Inhibition of NADPH oxidase attenuates vasospasm after experimental subarachnoid hemorrhage in rats.

    abstract:BACKGROUND AND PURPOSE:The purpose of this study is to investigate whether apocynin, an NADPH oxidase inhibitor, attenuates vasospasm after experimental subarachnoid hemorrhage (SAH) in rats. METHODS:Rats were subjected to endovascular perforation of the right anterior cerebral artery or sham surgery. Beginning 2 hour...

    journal_title:Stroke

    pub_type: 杂志文章,收录出版

    doi:10.1161/01.STR.0000163102.49888.b7

    authors: Zheng JS,Zhan RY,Zheng SS,Zhou YQ,Tong Y,Wan S

    更新日期:2005-05-01 00:00:00

  • Ultrasonic demonstration of external and internal carotid patency with common carotid occlusion: a preliminary report.

    abstract::Non-invasive ultrasonic imaging of the carotid bifurcation by duplex scanning and ultrasonic arteriography combined with pulsed Doppler spectrum analysis demonstrated patency of the external and internal carotid arteries distal to a common carotid occlusion in 3 patients. Common carotid occlusion is not invariably ass...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.11.3.249

    authors: Blackshear WM Jr,Phillips DJ,Bodily KC,Strandness DE Jr

    更新日期:1980-05-01 00:00:00

  • Fibrinogen concentration and risk of ischemic stroke and acute coronary events in 5113 patients with transient ischemic attack and minor ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:Fibrinogen is an independent risk factor for coronary events in population-based studies and in patients with coronary heart disease, but there is uncertainty about prediction of stroke, particularly in secondary prevention. METHODS:We studied unpublished data from 3 prospective studies of patie...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000141701.36371.d1

    authors: Rothwell PM,Howard SC,Power DA,Gutnikov SA,Algra A,van Gijn J,Clark TG,Murphy MF,Warlow CP

    更新日期:2004-10-01 00:00:00

  • Timing of Percutaneous Endoscopic Gastrostomy for Acute Ischemic Stroke: An Observational Study From the US Nationwide Inpatient Sample.

    abstract:BACKGROUND AND PURPOSE:Stroke guidelines recommend time-limited trials of nasogastric feeding prior to percutaneous endoscopic gastrostomy (PEG) tube placement. We sought to describe timing of PEG placement and identify factors associated with early PEG for acute ischemic stroke. METHODS:We designed a retrospective ob...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.116.015119

    authors: George BP,Kelly AG,Albert GP,Hwang DY,Holloway RG

    更新日期:2017-02-01 00:00:00

  • Damage to the Left Precentral Gyrus Is Associated With Apraxia of Speech in Acute Stroke.

    abstract:BACKGROUND AND PURPOSE:Apraxia of speech (AOS) is a motor speech disorder, which is clinically characterized by the combination of phonemic segmental changes and articulatory distortions. AOS has been believed to arise from impairment in motor speech planning/programming and differentiated from both aphasia and dysarth...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.115.010402

    authors: Itabashi R,Nishio Y,Kataoka Y,Yazawa Y,Furui E,Matsuda M,Mori E

    更新日期:2016-01-01 00:00:00

  • Delirium in an Acute Stroke Setting, Occurrence, and Risk Factors.

    abstract::Background and Purpose- Delirium is a common and serious complication of acute illness. We describe delirium occurrence in an unselected, acute stroke population. Methods- We collected data from consecutive stroke admissions. We performed comprehensive cognitive assessment within the first week including Diagnostic St...

    journal_title:Stroke

    pub_type: 临床试验,杂志文章

    doi:10.1161/STROKEAHA.119.025993

    authors: Shaw R,Drozdowska B,Taylor-Rowan M,Elliott E,Cuthbertson G,Stott DJ,Quinn TJ

    更新日期:2019-11-01 00:00:00

  • Delayed paraplegia after spinal cord ischemic injury requires caspase-3 activation in mice.

    abstract:BACKGROUND AND PURPOSE:Delayed paraplegia remains a devastating complication after ischemic spinal cord injury associated with aortic surgery and trauma. Although apoptosis has been implicated in the pathogenesis of delayed neurodegeneration, mechanisms responsible for the delayed paraplegia remain incompletely underst...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.110.600429

    authors: Kakinohana M,Kida K,Minamishima S,Atochin DN,Huang PL,Kaneki M,Ichinose F

    更新日期:2011-08-01 00:00:00

  • Inosine reduces ischemic brain injury in rats.

    abstract:BACKGROUND AND PURPOSE:Purinergic nucleoside inosine elicits protection and regeneration during various injuries. The purpose of this study was to examine the protective effects of inosine against cerebral ischemia. METHODS:Adult Sprague-Dawley rats were anesthetized. Inosine, hypoxathine, or vehicle was administered ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000155747.15679.04

    authors: Shen H,Chen GJ,Harvey BK,Bickford PC,Wang Y

    更新日期:2005-03-01 00:00:00

  • Cellular actions of halothane on cat cerebral arterial muscle.

    abstract::The effects of halothane on intracellular membrane potential (Em) and force development in cat MCA were studied. Halothane (0.07-0.14 mM/1) relaxed isolated MCA which had developed myogenic tone. Measurement of Em showed that halothane depolarized this preparation in a dose-dependent fashion in the face of vessel rela...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.16.4.680

    authors: Harder DR,Gradall K,Madden JA,Kampine JP

    更新日期:1985-07-01 00:00:00

  • Intracerebral transplantation of porcine choroid plexus provides structural and functional neuroprotection in a rodent model of stroke.

    abstract:BACKGROUND AND PURPOSE:Choroid plexus (CP) secretes a cocktail of neurotrophic factors. In the present study, CP from neonatal pigs was encapsulated within alginate microcapsules for in vitro and in vivo neuroprotective studies. METHODS:In vitro studies involved serum deprivation of rat embryonic cortical neurons and ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000138954.25825.0b

    authors: Borlongan CV,Skinner SJ,Geaney M,Vasconcellos AV,Elliott RB,Emerich DF

    更新日期:2004-09-01 00:00:00

  • Triggers of subarachnoid hemorrhage: role of physical exertion, smoking, and alcohol in the Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS).

    abstract:BACKGROUND AND PURPOSE:Unaccustomed strenuous physical exertion can trigger myocardial infarction, but little is known about the mechanisms precipitating subarachnoid hemorrhage (SAH). METHODS:We identified all cases of first-ever SAH among the combined populations (2.8 million) of 4 urban centers in Australia and New...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000077015.90334.A7

    authors: Anderson C,Ni Mhurchu C,Scott D,Bennett D,Jamrozik K,Hankey G,Australasian Cooperative Research on Subarachnoid Hemorrhage Study Group.

    更新日期:2003-07-01 00:00:00

  • CHA2DS2-VASc Score (Congestive Heart Failure, Hypertension, Age ≥75 [Doubled], Diabetes Mellitus, Prior Stroke or Transient Ischemic Attack [Doubled], Vascular Disease, Age 65-74, Female) for Stroke in Asian Patients With Atrial Fibrillation: A Korean Nat

    abstract:BACKGROUND AND PURPOSE:The CHA2DS2-VASc stroke score (congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65-74, female) is used in most guidelines for risk stratification in atrial fibrillation (AF), but most data for ...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.117.016926

    authors: Kim TH,Yang PS,Uhm JS,Kim JY,Pak HN,Lee MH,Joung B,Lip GYH

    更新日期:2017-06-01 00:00:00

  • Antegrade flow across incomplete vessel occlusions can be distinguished from retrograde collateral flow using 4-dimensional computed tomographic angiography.

    abstract:BACKGROUND AND PURPOSE:In acute stroke patients with intracranial vessel occlusion, angiographic demonstration of antegrade contrast opacification distal to the occlusion site (termed the "clot outline sign") has been associated with higher rates of vessel recanalization. We sought to determine whether antegrade flow c...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/STROKEAHA.112.668889

    authors: Frölich AM,Psychogios MN,Klotz E,Schramm R,Knauth M,Schramm P

    更新日期:2012-11-01 00:00:00

  • Intracarotid saline infusion improves outcome from incomplete ischemia in rats.

    abstract::Previous studies suggest that rheological changes associated with ischemia may produce postischemic hypoperfusion. We tested whether intracarotid or intravenous infusions of saline improve neurological outcome from incomplete cerebral ischemia in rats. Rats were anesthetized with 1.4% isoflurane in air, and ischemia w...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.22.6.797

    authors: Hoffman WE,Ferguson L,Thomas C,Albrecht RF

    更新日期:1991-06-01 00:00:00

  • Elevation of CRABP-I in the cerebrospinal fluid of patients with Moyamoya disease.

    abstract:BACKGROUND AND PURPOSE:The etiology of moyamoya disease (MMD) remains obscure. This study was undertaken to identify specific proteins associated with the pathogenesis of MMD. METHODS:We studied cerebrospinal fluid (CSF) from 20 patients with angiographically confirmed MMD (4 boys and 16 girls; age range, 3 to 13 year...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.STR.0000100159.43123.D7

    authors: Kim SK,Yoo JI,Cho BK,Hong SJ,Kim YK,Moon JA,Kim JH,Chung YN,Wang KC

    更新日期:2003-12-01 00:00:00

  • Recent advances of intervention to inhibit progression of carotid intima-media thickness in patients with type 2 diabetes mellitus.

    abstract:BACKGROUND AND PURPOSE:Type 2 diabetes is associated with a high cardiovascular morbidity and mortality. Recent advances of intervention studies in type 2 diabetes with use of carotid intima-media thickness (CIMT) measurement as a surrogate end point may allow for better understanding of the undetermined process of ath...

    journal_title:Stroke

    pub_type: 杂志文章,评审

    doi:10.1161/01.STR.0000236632.58323.cd

    authors: Yokoyama H,Katakami N,Yamasaki Y

    更新日期:2006-09-01 00:00:00

  • Platelet accumulation in regions of low blood flow during the postischemic period.

    abstract::Various studies indicate that after a latent interval, a progressive focal deterioration of microvascular perfusion can develop in zones of acute damage to the central nervous system (CNS). In order to obtain reliable information concerning the possibility of platelet participation in this phenomenon, platelet deposit...

    journal_title:Stroke

    pub_type: 杂志文章

    doi:10.1161/01.str.16.2.224

    authors: Obrenovitch TP,Hallenbeck JM

    更新日期:1985-03-01 00:00:00