Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults.

abstract：BACKGROUND AND PURPOSE:Our objective was to study age-specific prevalence, computed tomographic (CT) characteristics, risk factors, and the prognostic influence on stroke outcome of silent infarction in acute stroke patients. METHODS:The study was prospective and community-based and included 801 acute stroke patients,...

journal_title：Stroke

authors： Jørgensen HS,Nakayama H,Raaschou HO,Gam J,Olsen TS

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Incidental magnetic resonance diffusion-weighted imaging (DWI)-positive lesions, considered to represent small acute infarcts, have been detected in patients with cerebral small vessel diseases or cognitive impairment, but the prevalence in the community population is unknown. METHODS:DWI sequen...

journal_title：Stroke

authors： Batool S,O'Donnell M,Sharma M,Islam S,Dagenais GR,Poirier P,Lear SA,Wielgosz A,Teo K,Stotts G,McCreary CR,Frayne R,DeJesus J,Rangarajan S,Yusuf S,Smith EE,PURE Study Investigators.

更新日期：2014-07-01 00:00:00

abstract：:There have been numerous failures in the field of acute stroke therapy over many years, but the first large clinical trial showing preliminary indications of efficacy and safety of a neuroprotective drug, NXY-059, has now been fully reported. If confirmed, it will mean that a second therapy for acute stroke has been i...

journal_title：Stroke

authors： Zivin JA

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Results from large multicenter studies have shown that carotid endarterectomy, performed with low perioperative morbidity and mortality, is beneficial for patients with symptomatic carotid stenosis > or = 70% as calculated according to strict angiographic criteria. To apply these results in clini...

journal_title：Stroke

authors： Chang YJ,Golby AJ,Albers GW

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The modified Rankin Scale (mRS) is a popular primary stroke outcome measure, but its usefulness is limited by suboptimal reliability (inter-rater agreement). METHODS:We developed and tested the reliability of a simplified mRS questionnaire (smRSq) in 50 patients after stroke seen in outpatient c...

journal_title：Stroke

authors： Bruno A,Shah N,Lin C,Close B,Hess DC,Davis K,Baute V,Switzer JA,Waller JL,Nichols FT

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Embolization with coils is increasingly used for the treatment of intracranial aneurysms. To assess the percentage of complications, the percentage of aneurysm occlusion, and the short-term outcome, we performed a systematic review of studies on embolization with controlled detachable or pushable coils. SUM...

journal_title：Stroke

authors： Brilstra EH,Rinkel GJ,van der Graaf Y,van Rooij WJ,Algra A

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Middle cerebral artery (MCA) stenosis is a relatively rare occlusive disease with an annual stroke risk of approximately 7% to 8%. However, the frequent coincidence of cardiac or ipsilateral carotid artery disease may lead to difficulties in identifying the relevant embolizing source in symptomat...

journal_title：Stroke

authors： Nabavi DG,Georgiadis D,Mumme T,Zunker P,Ringelstein EB

更新日期：1996-08-01 00:00:00

abstract：:The value of the concomittant use of a real time frequency analyzer along with a continuous wave carotid Doppler scanner is demonstrated in this study of 118 cases. With a colour-coded Doppler scanner alone, internal carotid stenoses greater than 35% were diagnosed with a sensitivity of 95% and a specificity of 82%. W...

journal_title：Stroke

authors： Johnston KW,Brown PM,Kassam M

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The cerebral vasodilating effect of acetazolamide (ACZ) injection has been used as an index of the autoregulatory vasodilation (or cerebral perfusion reserve). The question of whether the ACZ test assesses the maximal autoregulatory vasodilating capacity is not definitely resolved. The effects of...

journal_title：Stroke

authors： Démolis P,Florence G,Thomas L,Tran Dinh YR,Giudicelli JF,Seylaz J,Alkayed NJ

更新日期：2000-02-01 00:00:00

abstract：:Various concentrations of acetylcholine (ACh) produced dose dependent relaxations of isolated, helical preparations of human cerebral arteries and these responses were blocked by atropine. The median effective concentration (EC50) of ACh was 6.1 +/- 0.2 X 10(-6)M. ACh produced dual responses in isolated dog cerebral a...

journal_title：Stroke

authors： Tsukahara T,Usui H,Taniguchi T,Shimohama S,Fujiwara M,Handa H

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Timing of carotid endarterectomy after stroke in a patient with a fixed neurological deficit remains an important but unresolved question. Early surgery has been associated with cerebral hemorrhage and infarct extension. Delayed endarterectomy exposes the patient to recurrent stroke and carotid occlusion. Th...

journal_title：Stroke

authors： Pritz MB

更新日期：1997-12-01 00:00:00

abstract：:Cerebral blood flow and clinical parameters were studied in 30 stroke patients at 15th, 30th, 60th, 90th days after the cerebral insult (Xenon 133 inhalation method). The clinical improvement was not accompanied by a progressive normalization of the CBF at rest. No relationship was found between the clinical data and ...

journal_title：Stroke

authors： Demeurisse G,Verhas M,Capon A,Paternot J

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The effect of smoking reduction on cardiovascular disease outcomes has not been studied in Asian populations. METHODS:A total of 475 734 Korean men aged 30 to 58 years, stratified into 9 groups based on smoking status at 2 different time points (1990 and 1992), were followed from 1992 to 2001 fo...

journal_title：Stroke

authors： Song YM,Cho HJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dysphagia is common after stroke and is a marker of poor prognosis. Early identification is important. This article reviews the merits and limitations of various assessment methods available to clinicians. METHODS:An electronic database search was performed of MEDLINE, EMBASE, and the Cochrane d...

journal_title：Stroke

authors： Ramsey DJ,Smithard DG,Kalra L

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We sought to determine the effects of aging on regional cerebral blood flow and ischemic brain damage in transient cerebral ischemia in rats. METHODS:Five adult (5-6 months) and five aged (18-22 months) female spontaneously hypertensive rats were subjected to 20 minutes of bilateral carotid occl...

journal_title：Stroke

authors： Yao H,Sadoshima S,Ooboshi H,Sato Y,Uchimura H,Fujishima M

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Pathogenetic classification of intracerebral hemorrhage (ICH), using systems such as SMASH-U (structural vascular lesions, medication, cerebral amyloid angiopathy [CAA], systemic disease, hypertension, or undetermined), is important in predicting functional outcomes and mortality in patients with...

journal_title：Stroke

authors： Yeh SJ,Tang SC,Tsai LK,Jeng JS

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Severe atherosclerosis in the aortic arch is associated with a high risk of recurrent vascular events, but the optimal antithrombotic strategy is unclear. METHODS:This prospective randomized controlled, open-labeled trial, with blinded end point evaluation (PROBE design) tested superiority of as...

journal_title：Stroke

authors： Amarenco P,Davis S,Jones EF,Cohen AA,Heiss WD,Kaste M,Laouénan C,Young D,Macleod M,Donnan GA,Aortic Arch Related Cerebral Hazard Trial Investigators.

更新日期：2014-05-01 00:00:00

abstract：:Background and Purpose- The impact of a mobile stroke unit (MSU) on access to intraarterial thrombectomy (IAT) is a prespecified BEST-MSU substudy (Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services). On the MSU, IAT decision-making steps, su...

journal_title：Stroke

authors： Czap AL,Grotta JC,Parker SA,Yamal JM,Bowry R,Sheth SA,Rajan SS,Hwang H,Singh N,Bratina P,Bryndziar T,Alexandrov AV,Alexandrov AW,Dusenbury W,Swatzell V,Jones W,Ackerson K,Schimpf B,Wright P,Jagolino-Cole AL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Reports of ischemic stroke affecting the hippocampus are rare. In this study we used diffusion-weighted MRI (DWI) to characterize patients with posterior circulation stroke involving the hippocampus. METHODS:Fifty-seven consecutive acute stroke patients with hippocampal infarct (HI) on DWI were ...

journal_title：Stroke

authors： Szabo K,Förster A,Jäger T,Kern R,Griebe M,Hennerici MG,Gass A

更新日期：2009-06-01 00:00:00

abstract：:Background and Purpose- Besides the established spot sign (SS) in computed tomography angiography (CTA), there is growing evidence that different imaging markers in noncontrast CT offer great value for outcome prediction in patients with intracerebral hemorrhage (ICH). However, it is unclear how the concurrent presenc...

journal_title：Stroke

authors： Sporns PB,Kemmling A,Schwake M,Minnerup J,Nawabi J,Broocks G,Wildgruber M,Fiehler J,Heindel W,Hanning U

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Matrix metalloproteinases (MMPs) and cysteine proteases (calpain and cathepsin B) play an important role in cell death and are upregulated after focal cerebral ischemia. Because there is a significant interaction between MMP-9 with calpain and cathepsin B, we investigated the role of E64d (a calp...

journal_title：Stroke

authors： Tsubokawa T,Solaroglu I,Yatsushige H,Cahill J,Yata K,Zhang JH

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke in young adults has a dramatic effect on life; therefore, we investigated the long-term functional outcome after transient ischemic attack, ischemic stroke, or intracerebral hemorrhage in adults aged 18 to 50 years. METHODS:We studied 722 young patients with first-ever stroke admitted bet...

journal_title：Stroke

authors： Synhaeve NE,Arntz RM,Maaijwee NA,Rutten-Jacobs LC,Schoonderwaldt HC,Dorresteijn LD,de Kort PL,van Dijk EJ,de Leeuw FE

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We investigated the intra- and interrater reliability of ischemic lesion volumes measurements assessed by different MRI sequences at various times from onset. METHODS:Ischemic lesion volumes were measured for intrarater reliability using diffusion-weighted (DWI), mean transit time (MTT) perfusio...

journal_title：Stroke

authors： Luby M,Bykowski JL,Schellinger PD,Merino JG,Warach S

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The current report details our initial periprocedural experience with Wingspan (Boston Scientific/Target), the first self-expanding stent system designed for the treatment of intracranial atheromatous disease. METHODS:All patients undergoing angioplasty and stenting with the Gateway balloon-Wing...

journal_title：Stroke

authors： Fiorella D,Levy EI,Turk AS,Albuquerque FC,Niemann DB,Aagaard-Kienitz B,Hanel RA,Woo H,Rasmussen PA,Hopkins LN,Masaryk TJ,McDougall CG

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The PIWI-interacting RNA (piRNA) is the most predominant RNA species in eukaryotes. The piRNA are a class of noncoding RNAs that bind and degrade the RNA formed by the transposons to control the transposon-induced gene mutations. The role of piRNA after focal ischemia is not yet evaluated. METHO...

journal_title：Stroke

authors： Dharap A,Nakka VP,Vemuganti R

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolytic treatment of stroke carries the risk of hemorrhagic transformation. Therefore, the potential of MRI for prediction of recombinant tissue plasminogen activator (rtPA)-induced bleeding is explored to identify patients in whom rtPA treatment may provoke such complications. METHODS:Spon...

journal_title：Stroke

authors： Neumann-Haefelin C,Brinker G,Uhlenküken U,Pillekamp F,Hossmann KA,Hoehn M

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Potassium channels are important regulators of resting tone in large cerebral arteries, but their activity and distribution may vary according to vessel location and species studied. In the cerebral microcirculation in vivo, however, these channels appear to be silent at rest. Our goal was to det...

journal_title：Stroke

authors： Horiuchi T,Dietrich HH,Tsugane S,Dacey RG Jr

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aim to investigate whether histopathologic examination of thrombi retrieved from acute ischemic stroke patients undergoing endovascular treatment could distinguish cancer-related stroke from other etiologies. METHODS:Thrombi from patients undergoing endovascular treatment were analyzed. The e...

journal_title：Stroke

authors： Fu CH,Chen CH,Lin YH,Lee CW,Tsai LK,Tang SC,Shun CT,Jeng JS

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Studies using animal models of stroke have shown that human serum albumin (HSA) significantly ameliorates cerebral ischemic injury after both transient and permanent ischemia, even when administered after the onset of ischemia or reperfusion. The mechanism of this effect remains uncertain, and pr...

journal_title：Stroke

authors： Gum ET,Swanson RA,Alano C,Liu J,Hong S,Weinstein PR,Panter SS

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Chronic kidney disease may increase the risk for ischemic stroke or systemic embolism in patients with nonvalular atrial fibrillation (AF). We conducted a meta-analysis to summarize all published studies to investigate the link between chronic kidney disease and risk of thromboembolic events in A...

journal_title：Stroke

authors： Zeng WT,Sun XT,Tang K,Mei WY,Liu LJ,Xu Q,Cheng YJ

更新日期：2015-01-01 00:00:00