Vertebrobasilar stenosis predicts high early recurrent stroke risk in posterior circulation stroke and TIA.

abstract：:The levels of lipid peroxides, determined as thiobarbituric acid reactive substances (TBARS), and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), were examined in the blood from stroke-prone spontaneously hypertensive rats (SHRSP), with and without cerebral lesions, and normotensive W...

journal_title：Stroke

authors： Tomita I,Sano M,Serizawa S,Ohta K,Katou M

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The independent contribution of insulin resistance to atherosclerosis is still under debate. We compared associations of 2 different indices of insulin resistance, the Homeostasis Model Assessment (HOMA) index and kITT from a short insulin tolerance test with carotid atherosclerosis. METHODS:A t...

journal_title：Stroke

authors： Sourij H,Schmoelzer I,Dittrich P,Paulweber B,Iglseder B,Wascher TC

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Understanding on distinct subsets of endothelial progenitor cells may provide insights of endothelial dysfunction or repair in the acute ischemic event. Recent in vitro data have reported the colony-forming unit (CFU) and outgrowth cell population as a subset of endothelial progenitor cells. In t...

journal_title：Stroke

authors： Chu K,Jung KH,Lee ST,Park HK,Sinn DI,Kim JM,Kim DH,Kim JH,Kim SJ,Song EC,Kim M,Lee SK,Roh JK

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because thromboembolic events are frequently observed in primary antiphospholipid syndrome (PAPS), we assessed the risk factors for new thrombotic episodes. METHODS:Fifty-six PAPS patients (mean age, 37+/-10 years) were prospectively studied for 5 years. The preliminary Sapporo classification cr...

journal_title：Stroke

authors： Turiel M,Sarzi-Puttini P,Peretti R,Rossi E,Atzeni F,Parsons W,Doria A

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The joint effect of risk factors on the risk of aneurysmal SAH (aSAH) has been studied sparsely. METHODS:We examined the potential synergism between cigarette smoking, hypertension, and regular alcohol consumption and the risk of aSAH in a prospective, population-based cohort of participants fro...

journal_title：Stroke

authors： Lindekleiv H,Sandvei MS,Romundstad PR,Wilsgaard T,Njølstad I,Ingebrigtsen T,Vik A,Mathiesen EB

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is not known what fraction of patients with symptomatic cerebral aneurysms are misdiagnosed at initial medical presentation. It is also not clear whether misdiagnosed patients more frequently deteriorate before definitive aneurysm diagnosis and therapy or achieve a poorer outcome than correctl...

journal_title：Stroke

authors： Mayer PL,Awad IA,Todor R,Harbaugh K,Varnavas G,Lansen TA,Dickey P,Harbaugh R,Hopkins LN

更新日期：1996-09-01 00:00:00

abstract：:We reviewed demographic data on patients having 2,256 carotid endarterectomies in eight large hospitals in North Carolina to determine the frequency of blacks among these patients. Blacks comprised only 4.6% of the patients having carotid endarterectomy even though they comprised 26% of all patients discharged and 22%...

journal_title：Stroke

authors： Maxwell JG,Rutherford EJ,Covington D,Clancy TV,Tackett AD,Robinson N,Johnson G Jr

更新日期：1989-01-01 00:00:00

abstract：:Thromboxane synthetase activity is selectively inhibited by (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propenoic acid hydrochloride monohydrate (OKY-046). A single dose of 100 mg OKY-046 was orally administered to patients with ischemic cerebrovascular disease and healthy volunteers. Platelet aggregation and thromboxane B...

journal_title：Stroke

authors： Uyama O,Nagatsuka K,Nakabayashi S,Isaka Y,Yoneda S,Kimura K,Abe H

更新日期：1985-03-01 00:00:00

abstract：:We report two patients with mixed transcortical aphasia following left frontal lobe infarctions. Although there was no evidence of anatomic isolation of the speech area on computed tomograms or magnetic resonance imaging scans, single-photon emission computed tomography in one case demonstrated diminished blood flow o...

journal_title：Stroke

authors： Rapcsak SZ,Krupp LB,Rubens AB,Reim J

更新日期：1990-06-01 00:00:00

abstract：:We studied the pattern and outcome of strokes in 200 Saudi patients. Cerebral infarction constituted 87% of strokes, subarachnoid hemorrhage 4.5%, cerebral hemorrhage 6.5%, and venous infarction 2%. The vessel most commonly involved was part or all of the middle cerebral artery, constituting 52% (90) of the 174 arteri...

journal_title：Stroke

authors： Yaqub BA,Shamena AR,Kolawole TM,Patel PJ

更新日期：1991-09-01 00:00:00

abstract：:There is a strong link between antiphospholipid antibodies and stroke. Retrospective studies indicate that these patients are generally young, often have had prior thrombotic events including stroke, frequently complain of headaches, and often experience amaurosis fugax. Cardiac valvular lesions, particularly involvin...

journal_title：Stroke

authors： Hess DC

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:"Incidental" MRI white matter (WM) lesions, comprising periventricular lesions (PVLs) and deep subcortical lesions (DSCLs), are common in the aging brain. Direct evidence of ischemia associated with incidental WM lesions (WMLs) has been lacking, and their pathogenesis is unresolved. METHODS:A po...

journal_title：Stroke

authors： Fernando MS,Simpson JE,Matthews F,Brayne C,Lewis CE,Barber R,Kalaria RN,Forster G,Esteves F,Wharton SB,Shaw PJ,O'Brien JT,Ince PG,MRC Cognitive Function and Ageing Neuropathology Study Group.

更新日期：2006-06-01 00:00:00

abstract：:We investigated the temporal threshold for focal cerebral infarction in the spontaneously hypertensive rat. The right middle cerebral artery and common carotid artery were occluded for 0, 1, 2, 3, 4, or 24 hours, and all the animals were sacrificed 24 hours after the onset of ischemia. Cortical infarct volumes and ede...

journal_title：Stroke

authors： Kaplan B,Brint S,Tanabe J,Jacewicz M,Wang XJ,Pulsinelli W

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lower birth weight is associated with increased risk of stroke, but little is known about the mechanism for this association or influence in addition to vascular risk factors. We investigated whether there was an association between birth parameters and imaging markers of white matter integrity i...

journal_title：Stroke

authors： Shenkin SD,Bastin ME,Macgillivray TJ,Deary IJ,Starr JM,Wardlaw JM

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The CHA2DS2-VASc stroke score (congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65-74, female) is used in most guidelines for risk stratification in atrial fibrillation (AF), but most data for ...

journal_title：Stroke

authors： Kim TH,Yang PS,Uhm JS,Kim JY,Pak HN,Lee MH,Joung B,Lip GYH

更新日期：2017-06-01 00:00:00

abstract：:Background and Purpose- Perihemorrhagic edema (PHE) is associated with poor outcome after intracerebral hemorrhage (ICH). Infiltration of immune cells is considered a major contributor of PHE. Recent studies suggest that immunomodulation via S1PR (sphingosine-1-phosphate receptor) modulators improve outcome in ICH. Si...

journal_title：Stroke

authors： Bobinger T,Manaenko A,Burkardt P,Beuscher V,Sprügel MI,Roeder SS,Bäuerle T,Seyler L,Nagel AM,Linker RA,Engelhorn T,Dörfler A,Horsten SV,Schwab S,Huttner HB

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Effects of anoxic stress on cerebrovascular responses to calcitonin gene-related peptide (CGRP) have not been examined previously. We determined the effects of total global ischemia on cerebral arteriolar responses to CGRP in newborn pigs. METHODS:Piglets were anesthetized and ventilated with a ...

journal_title：Stroke

authors： Louis TM,Meng W,Bari F,Errico RA,Busija DW

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite the reported functional recovery in transplanted stroke models and patients, the mechanism of action underlying stem cell therapy remains not well understood. Here, we examined the role of stem cell-mediated vascular repair in stroke. METHODS:Adult rats were exposed to transient occlusio...

journal_title：Stroke

authors： Ishikawa H,Tajiri N,Shinozuka K,Vasconcellos J,Kaneko Y,Lee HJ,Mimura O,Dezawa M,Kim SU,Borlongan CV

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To investigate the efficacy of bone marrow mononuclear cell (BMMNC) treatment against ischemic white matter (WM) damage in a hypoperfused brain. METHODS:Mice were administered intravenous treatment of vehicle, spleen-derived marrow mononuclear cells (MNCs), or BMMNCs (5 × 10⁶ cells) obtained fro...

journal_title：Stroke

authors： Fujita Y,Ihara M,Ushiki T,Hirai H,Kizaka-Kondoh S,Hiraoka M,Ito H,Takahashi R

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The etiology of stroke in the young is different from that in older patients and remains unknown in almost one third of the cases. To gain further insight into both pathogenic and etiologic determinants, we prospectively studied a large number of consecutive young adults with focal cerebral ische...

journal_title：Stroke

authors： Carolei A,Marini C,Ferranti E,Frontoni M,Prencipe M,Fieschi C

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Purinergic nucleoside inosine elicits protection and regeneration during various injuries. The purpose of this study was to examine the protective effects of inosine against cerebral ischemia. METHODS:Adult Sprague-Dawley rats were anesthetized. Inosine, hypoxathine, or vehicle was administered ...

journal_title：Stroke

authors： Shen H,Chen GJ,Harvey BK,Bickford PC,Wang Y

更新日期：2005-03-01 00:00:00

abstract：:We have evaluated carotid gamma imaging using 111Indium-labelled platelets in the diagnosis of carotid artery disease and measured the accumulation of labelled platelets on endarterectomy specimens. Autologous 111In labelled platelets were injected in 25 patients with TIA. Gamma images were then taken daily and indepe...

journal_title：Stroke

authors： Goldman M,Leung JO,Aukland A,Hawker RJ,Drolc Z,McCollum CN

更新日期：1983-09-01 00:00:00

abstract：:Endothelium dysfunction may result from increased production of reactive oxygen species and decreased availability of nitric oxide. Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (ie, statins) exert cholesterol-independent vasoprotective effects that are mediated, in part, through the inhibiti...

journal_title：Stroke

authors： Endres M,Laufs U

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS:As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at...

journal_title：Stroke

authors： Ballard C,Rowan E,Stephens S,Kalaria R,Kenny RA

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Efforts to reduce disparities in recurrent stroke among Black and Latino stroke survivors have met with limited success. We aimed to determine the effect of peer education on secondary stroke prevention among predominantly minority stroke survivors. METHODS:Between 2009 and 2012, we enrolled 600...

journal_title：Stroke

authors： Kronish IM,Goldfinger JZ,Negron R,Fei K,Tuhrim S,Arniella G,Horowitz CR

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is a major risk factor for ischemic stroke and its prevalence increases steeply with age. Population-based data on its influence on stroke outcome are scarce. METHODS:We evaluated the prevalence of AF and its influence on prognosis in patients with a first-ever ischemic ...

journal_title：Stroke

authors： Marini C,De Santis F,Sacco S,Russo T,Olivieri L,Totaro R,Carolei A

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A high rate of postprocedure complications in the Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis (SAMMPRIS) trial has raised concerns whether such results are representative of intracranial stent placement in actual routine practice. METHODS:Using the Nationwide In...

journal_title：Stroke

authors： Siddiq F,Adil MM,Norby K,Qureshi AI

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Delayed cerebral ischemia and infarction due to reduced CBF remains the leading cause of poor outcome after aneurysmal subarachnoid hemorrhage. Hypertonic saline (HS) is associated with an increase in CBF. This study explores whether CBF enhancement with HS in patients with poor-grade subarachnoi...

journal_title：Stroke

authors： Al-Rawi PG,Tseng MY,Richards HK,Nortje J,Timofeev I,Matta BF,Hutchinson PJ,Kirkpatrick PJ

更新日期：2010-01-01 00:00:00

abstract：:A new technique is described for the autoradiographic determination of regional brain glucose metabolism employing 14C labeled glucose as substrate and measurement principles previously described for whole brain. Regional glucose values correlate closely with those reported for the 14C-deoxyglucose technique. The meth...

journal_title：Stroke

authors： Hawkins R,Hass WK,Ransohoff J

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prominent posterior cerebral artery (PCA) laterality upon 3-dimensional time-of-flight magnetic resonance angiography is often encountered in patients with middle cerebral artery occlusion. We hypothesized that this sign is correlated with improved functional outcome in patients with middle cereb...

journal_title：Stroke

authors： Ichijo M,Miki K,Ishibashi S,Tomita M,Kamata T,Fujigasaki H,Mizusawa H

更新日期：2013-02-01 00:00:00