Biphasic striatal dopamine release during transient ischemia and reperfusion in gerbils.

abstract：:We determined the immediate effects of pentoxifylline on cerebral blood flow in 10 patients with cerebrovascular disease; four received 400 mg and six received 800 mg pentoxifylline orally. Regional cerebral blood flow was measured before (baseline) and 2, 4, and 6 hours after pentoxifylline administration using the x...

journal_title：Stroke

authors： Bowton DL,Stump DA,Prough DS,Toole JF,Lefkowitz DS,Coker L

更新日期：1989-12-01 00:00:00

abstract：:The intact omentum of 13 monkeys was lengthened, placed subcutaneously, and laid on the left cerebral hemisphere prior to occluding the left middle cerebral artery. Two of these 13 monkeys developed left cerebral infarct and a right hemiparesis. Nine other monkeys had their left middle cerebral artery occluded without...

journal_title：Stroke

authors： Goldsmith HS,Duckett S,Chen WF

更新日期：1978-05-01 00:00:00

abstract：:Occlusion of the anterior cerebral artery is a rare condition. A review of CT scans from 413 patients with ischemic infarction confirmed this low relative incidence: only 3% of CT scans evidencing infarction involved the territory of the anterior cerebral artery. Four major mechanisms of anterior cerebral artery occlu...

journal_title：Stroke

authors： Gacs G,Fox AJ,Barnett HJ,Vinuela F

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Differences exist between European countries in the proportion of patients who die or become dependent after stroke. The aim of the present study was to identify differences in the use of time by stroke patients in 4 rehabilitation centers in 4 European countries. METHODS:In each of the 4 center...

journal_title：Stroke

authors： De Wit L,Putman K,Dejaeger E,Baert I,Berman P,Bogaerts K,Brinkmann N,Connell L,Feys H,Jenni W,Kaske C,Lesaffre E,Leys M,Lincoln N,Louckx F,Schuback B,Schupp W,Smith B,De Weerdt W

更新日期：2005-09-01 00:00:00

abstract：:Previous studies suggest that rheological changes associated with ischemia may produce postischemic hypoperfusion. We tested whether intracarotid or intravenous infusions of saline improve neurological outcome from incomplete cerebral ischemia in rats. Rats were anesthetized with 1.4% isoflurane in air, and ischemia w...

journal_title：Stroke

authors： Hoffman WE,Ferguson L,Thomas C,Albrecht RF

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hyperglycemia may worsen brain injury during acute cerebral infarction. We tested the feasibility and tolerability of aggressive hyperglycemia correction with intravenous insulin compared with usual care during acute cerebral infarction. METHODS:We conducted a randomized, multicenter, blinded pi...

journal_title：Stroke

authors： Bruno A,Kent TA,Coull BM,Shankar RR,Saha C,Becker KJ,Kissela BM,Williams LS

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Evidence suggests that an alteration in cerebral hemodynamics plays a relevant role in the occurrence of stroke in patients with carotid occlusion. The purpose of the present study was to evaluate the relationships among baseline characteristics, type and number of collateral pathways, cerebral v...

journal_title：Stroke

authors： Vernieri F,Pasqualetti P,Matteis M,Passarelli F,Troisi E,Rossini PM,Caltagirone C,Silvestrini M

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because the diagnosis and treatment of carotid artery disease may reduce the rate of stroke, the aim of this study was to determine whether a diet intervention was associated with incident carotid artery disease. METHODS:Participants were 48 835 postmenopausal women aged 50 to 79 years who were ...

journal_title：Stroke

authors： Allison MA,Aragaki A,Eaton C,Li W,Van Horn L,Daviglus ML,Berger JS

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:To investigate differences between symptomatic and asymptomatic retinal embolism regarding the frequency and source of cerebral microemboli. METHODS:Thirty-seven patients with transient monocular blindness or retinal infarction and 27 patients (29 eyes) with asymptomatic retinal embolism were prospectively enr...

journal_title：Stroke

authors： Wijman CA,Gomes JA,Winter MR,Koleini B,Matjucha IC,Pochay VE,Babikian VL

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A right-to-left shunt can be identified by contrast transcranial Doppler ultrasonography (c-TCD) at rest and/or after a Valsalva maneuver (VM) or by arterial blood gas (ABG) measurement. We assessed the influence of controlled strain pressures and durations during VM on the right-to-left passage ...

journal_title：Stroke

authors： Devuyst G,Piechowski-Józwiak B,Karapanayiotides T,Fitting JW,Kémeny V,Hirt L,Urbano LA,Arnold P,van Melle G,Despland PA,Bogousslavsky J

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recombinant activated factor VII (rFVIIa) reduces hematoma expansion and improves outcome after intracerebral hemorrhage (ICH), with an apparent increase in nonfatal thromboembolic events (TEs) with higher doses. Despite low incidences of such events in rFVIIa-treated hemophiliacs, the frequency ...

journal_title：Stroke

authors： Diringer MN,Skolnick BE,Mayer SA,Steiner T,Davis SM,Brun NC,Broderick JP

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Preceding infection as an important risk factor for ischemic stroke has been reported but neglected for hemorrhagic stroke, especially in young and middle-aged patients. This study investigates whether newly diagnosed leptospirosis is associated with an increased risk of stroke. METHODS:We ident...

journal_title：Stroke

authors： Li KY,Chou MC,Wei JC,Lin MC,Hung YM,Chang R

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND AND PURPOSE:Eligibility criteria determine the external validity (generalizability) of the results of randomized controlled trials. To increase the number of outcome events, and hence statistical power, some recent stroke prevention trials have required additional vascular risk factors for eligibility. METH...

journal_title：Stroke

authors： Howard SC,Algra A,Warlow CP,Rothwell PM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:We studied 60 patients longitudinally to examine relations between regional cerebral blood flow and depressive states after stroke. METHODS:Poststroke depressive states were assessed by the Zung Self-Rating Depression Scale (SDS). Regional cerebral blood flow was measured using the 133xenon inhalation metho...

journal_title：Stroke

authors： Yamaguchi S,Kobayashi S,Koide H,Tsunematsu T

更新日期：1992-12-01 00:00:00

abstract：:We have investigated the effects of a reduced regional or a reduced body temperature, on pial arteriolar response to a variety of vasoactive stimuli. This has been done by studying the effects of these stimuli on groups of mice with different body temperatures, or with different temperatures of the artificial cerebros...

journal_title：Stroke

authors： Rosenblum WI,Segreti AC

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Plasminogen activator inhibitor type 1 (PAI-1) is the main inhibitor of fibrinolysis, and high levels may increase the risk of cardiovascular disease. The 4G/5G polymorphism affects PAI-1 gene transcription with lower levels of plasma PAI-1 in the presence of the 5G allele. We investigated whethe...

journal_title：Stroke

authors： Hoekstra T,Geleijnse JM,Kluft C,Giltay EJ,Kok FJ,Schouten EG

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Mild hypothermia is possibly the single most effective method of cerebroprotection developed to date. However, many questions regarding mild hypothermia remain to be addressed before its potential implementation in the treatment of human stroke. Here we report the results of 2 studies designed to...

journal_title：Stroke

authors： Maier CM,Ahern Kv,Cheng ML,Lee JE,Yenari MA,Steinberg GK

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Clinical development of novel neuroprotection therapies for the treatment of brain injury has been unsuccessful. One critical limitation is the lack of a viable therapeutic treatment window (TW). In this study, we evaluated the neuroprotection TW for the proteosome inhibitor MLN519 after ischemia...

journal_title：Stroke

authors： Williams AJ,Berti R,Dave JR,Elliot PJ,Adams J,Tortella FC

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with...

journal_title：Stroke

authors： Thorén M,Azevedo E,Dawson J,Egido JA,Falcou A,Ford GA,Holmin S,Mikulik R,Ollikainen J,Wahlgren N,Ahmed N

更新日期：2017-09-01 00:00:00

abstract：:Background and Purpose- Depression and anxiety are common after stroke/transient ischemic attack (TIA). These conditions are associated with poor functional outcome and worse quality of life. However, few studies have explored predictors of poststroke risk of generalized anxiety, especially in patients without comorbi...

journal_title：Stroke

authors： Kapoor A,Si K,Yu AYX,Lanctot KL,Herrmann N,Murray BJ,Swartz RH

更新日期：2019-09-01 00:00:00

abstract：:In a case-control study of 73 cases of cerebral hematoma diagnosed by CT scan, significant risk factors were history of hypertension, chronic alcoholism, evidence of hepatic disease, EKG abnormalities and high hematocrit values. Initial blood pressure was significantly higher in cases, but blood pressure on the third ...

journal_title：Stroke

authors： Calandre L,Arnal C,Ortega JF,Bermejo F,Felgeroso B,del Ser T,Vallejo A

更新日期：1986-11-01 00:00:00

abstract：:Leukoaraiosis quantified by computerized densitometric measurements of reduced Hounsfield numbers was correlated with local cerebral blood flow on the same computed tomographic images of 35 patients with multi-infarct dementia and 16 age-matched elderly normal volunteers. The ratio for area of frontal leukoaraiosis to...

journal_title：Stroke

authors： Kawamura J,Meyer JS,Terayama Y,Weathers S

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some studies have suggested a link between impaired cerebral hemodynamics and stroke in patients with carotid stenosis. The aim of this study was to assess the effects of severe carotid stenosis on cerebrovascular reactivity and the possible changes after endarterectomy. METHODS:Using bilateral ...

journal_title：Stroke

authors： Silvestrini M,Troisi E,Matteis M,Cupini LM,Caltagirone C

更新日期：1996-11-01 00:00:00

abstract：:Thromboxane synthetase activity is selectively inhibited by (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propenoic acid hydrochloride monohydrate (OKY-046). A single dose of 100 mg OKY-046 was orally administered to patients with ischemic cerebrovascular disease and healthy volunteers. Platelet aggregation and thromboxane B...

journal_title：Stroke

authors： Uyama O,Nagatsuka K,Nakabayashi S,Isaka Y,Yoneda S,Kimura K,Abe H

更新日期：1985-03-01 00:00:00

abstract：:Bay U 3405 is a novel thromboxane receptor blocker. The present investigations describe its effects on experimental canine and porcine cardiac damage. In anesthetized dogs, a coronary artery was occluded for 6 hours and reperfused for 30 minutes. Bay U 3405 was administered intravenously 15 minutes after occlusion (1 ...

journal_title：Stroke

authors： Fiedler VB,Seuter F,Perzborn E

更新日期：1990-12-01 00:00:00

abstract：:Background and Purpose- Given inconclusive studies, it is debated whether clinical and imaging characteristics, as well as functional outcome, differ among patients with intracerebral hemorrhage (ICH) related to vitamin K antagonists (VKA) versus non-vitamin K antagonist (NOAC)-related ICH. Notably, clinical character...

journal_title：Stroke

authors： Gerner ST,Kuramatsu JB,Sembill JA,Sprügel MI,Hagen M,Knappe RU,Endres M,Haeusler KG,Sobesky J,Schurig J,Zweynert S,Bauer M,Vajkoczy P,Ringleb PA,Purrucker JC,Rizos T,Volkmann J,Müllges W,Kraft P,Schubert AL,Erbgut

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke is a major healthcare problem in both the United States (US) and the United Kingdom (UK). Little comparative data are available concerning how generalist physicians in the two countries approach the management of patients at high risk of stroke. METHODS:Contemporaneous surveys of random s...

journal_title：Stroke

authors： Goldstein LB,Farmer A,Matchar DB

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some clinical models, like California ABCD and unified ABCD2 scores, are now available to predict the early risk of stroke after a TIA. Despite the transitivity of symptoms, DWI identified an area of acute brain ischemia in almost half of patients. It would be interesting to know how the presence...

journal_title：Stroke

authors： Purroy F,Begué R,Quílez A,Piñol-Ripoll G,Sanahuja J,Brieva L,Setó E,Gil MI

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Current guidelines recommend against routine auscultation of carotid arteries, believing that carotid bruits are poor predictors of either underlying carotid stenosis or stroke risk in asymptomatic patients. We investigated whether the presence of a carotid bruit is associated with increased risk...

journal_title：Stroke

authors： Pickett CA,Jackson JL,Hemann BA,Atwood JE

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:When carotid artery tandem lesions are present, the benefits of carotid endarterectomy (CEA) to reduce recurrent stroke remain uncertain. The present retrospective cohort study aimed to determine the clinical outcomes of CEA for carotid artery tandem stenosis that was diagnosed by contrast-enhanc...

journal_title：Stroke

authors： Han Y,Park H,Kwon SU,Kang DW,Lee DH,Kwon H,Kwon TW,Cho YP,Kim GE

更新日期：2014-11-01 00:00:00