Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model.

abstract：BACKGROUND AND PURPOSE:Reaching movements made with the affected arm in hemiparetic patients are often accompanied by compensatory trunk or shoulder girdle movements, which extend the reach of the arm. We investigated the effects of the suppression of these compensatory movements on reaching ability in hemiparetic indi...

journal_title：Stroke

authors： Michaelsen SM,Luta A,Roby-Brami A,Levin MF

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Using the dexamethasone suppression test, we studied the suppressibility of the cortisol axis and its clinical determinants at various time points after stroke. A major aim was to examine the dexamethasone test as a diagnostic tool for the diagnosis of major depression in stroke patients. METHOD...

journal_title：Stroke

authors： Aström M,Olsson T,Asplund K

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We earlier reported that risk factors for stroke prepare brain stem tissue for a modified Shwartzman reaction, including the development of ischemia and hemorrhage and the production of tumor necrosis factor-alpha, after a provocative dose of lipopolysaccharide. In the present study, we sought to...

journal_title：Stroke

authors： Sirén AL,Liu Y,Feuerstein G,Hallenbeck JM

更新日期：1993-06-01 00:00:00

abstract：:Five patients with nonseptic cerebral embolism of cardiac origin are reported in whom early anticoagulant therapy resulted in clinical deterioration or death from frank hemorrhage into the acute infarct. In each patient an initial CT scan excluded the presence of intracerebral hemorrhage and a second CT scan, after cl...

journal_title：Stroke

authors： Shields RW Jr,Laureno R,Lachman T,Victor M

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To date, studies on neonatal stroke have mainly focused on cortical stroke. We have focused on perforator strokes, noncortical strokes in the arterial vascular perforator area. We sought to identify risk factors and evaluate clinical presentation and neuroimaging findings for neonatal perforator ...

journal_title：Stroke

authors： Ecury-Goossen GM,Raets MM,Lequin M,Feijen-Roon M,Govaert P,Dudink J

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few pediatric reports of thrombolysis exist. We sought to determine national rates of thrombolysis among pediatric ischemic stroke patients using a national database. METHODS:Patients between the ages of 1 and 17 years, entered in the Nationwide Inpatient Sample between 2000 and 2003, with Inter...

journal_title：Stroke

authors： Janjua N,Nasar A,Lynch JK,Qureshi AI

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To test the safety and recanalization efficacy of intra-arterial local delivery of plasminogen activators in acute ischemic stroke, a randomized trial of recombinant pro-urokinase (rpro-UK) versus placebo was undertaken in patients with angiographically documented proximal middle cerebral artery ...

journal_title：Stroke

authors： del Zoppo GJ,Higashida RT,Furlan AJ,Pessin MS,Rowley HA,Gent M

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In acute stroke care, rapid but careful evaluation of patients is mandatory but requires an experienced stroke neurologist. Telemedicine offers the possibility of bringing such expertise quickly to more patients. This study tested for the first time whether remote video examination is feasible an...

journal_title：Stroke

authors： Handschu R,Littmann R,Reulbach U,Gaul C,Heckmann JG,Neundörfer B,Scibor M

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We hypothesize that in acute middle cerebral artery stroke, thrombus lengths measured in thin-slice nonenhanced CT images define a limit beyond which systemic thrombolysis will fail to recanalize occluded arteries. METHODS:In 138 patients who presented with acute middle cerebral artery stroke an...

journal_title：Stroke

authors： Riedel CH,Zimmermann P,Jensen-Kondering U,Stingele R,Deuschl G,Jansen O

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prophylactic administration of simvastatin has been shown to protect against brain damage and its long-lasting behavioral consequences in neonatal rats. To establish the drug treatment window, we evaluated the effectiveness of simvastatin administered at different intervals before and after strok...

journal_title：Stroke

authors： Balduini W,Mazzoni E,Carloni S,De Simoni MG,Perego C,Sironi L,Cimino M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The influence of a nocturnal blood pressure dip on stroke recurrence has not yet been clarified. In this pilot study, we attempted to establish a correlation of the nocturnal blood pressure dip with stroke recurrence and development of new silent ischemic lesions in patients with chronic ischemic...

journal_title：Stroke

authors： Nakamura K,Oita J,Yamaguchi T

更新日期：1995-08-01 00:00:00

abstract：:Cardioembolic stroke is a complex disease resulting from the interaction of numerous factors. Using data from Genes Affecting Stroke Risk and Outcome Study (GASROS), we show that a multivariate predictive model built using Bayesian networks is able to achieve a predictive accuracy of 86% on the fitted values as comput...

journal_title：Stroke

authors： Ramoni RB,Himes BE,Sale MM,Furie KL,Ramoni MF

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The diagnosis and quantification of microangiopathy in dementia is difficult. The assessment of small-vessel disease requires expensive and sophisticated nuclear medicine techniques. This study was performed to identify microangiopathy related to the integrity of cerebral microcirculation by sono...

journal_title：Stroke

authors： Puls I,Hauck K,Demuth K,Horowski A,Schliesser M,Dörfler P,Scheel P,Toyka KV,Reiners K,Schöning M,Becker G

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral microembolic signals detected by transcranial Doppler are frequent during carotid angioplasty with stenting and carotid endarterectomy (CEA). Their potential harmful effects on the brain are, however, unclear. The aim of this study was to relate the frequency and type of per-procedural m...

journal_title：Stroke

authors： Skjelland M,Krohg-Sørensen K,Tennøe B,Bakke SJ,Brucher R,Russell D

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The CHA2DS2-VASc score aims to improve risk stratification of ischemic stroke among patients with atrial fibrillation to identify those who can safely forego oral anticoagulation. Oral anticoagulation treatment guidelines remain uncertain for CHA2DS2-VASc score of 1. We conducted a systematic rev...

journal_title：Stroke

authors： Joundi RA,Cipriano LE,Sposato LA,Saposnik G,Stroke Outcomes Research Working Group.

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a marker of unstable atherosclerotic plaque, and is predictive of both primary and secondary stroke in population-based studies. METHODS:We conducted a prospective study of patients with acute TIA who presented to the ED. Clinical risk sco...

journal_title：Stroke

authors： Cucchiara BL,Messe SR,Sansing L,MacKenzie L,Taylor RA,Pacelli J,Shah Q,Kasner SE

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Early neurological deterioration (END) occurs in ≥20% of single small subcortical infarctions (SSSIs; axial diameter ≤20 mm in the perforator territories) and deters functional recovery. Both microvasculopathies and atherosclerosis have been proposed to independently contribute to the occurrence ...

journal_title：Stroke

authors： Jeong HG,Kim BJ,Yang MH,Han MK,Bae HJ

更新日期：2015-03-01 00:00:00

abstract：:Correlations between changes in regional, cortical, cerebral blood flow (rCBF) and histological changes in the corresponding brain regions were examined following middle cerebral arterial occlusion in 24 cats. In all animals, the duration of arterial occlusion was 2 hours followed by 2 hours of recirculation. The anim...

journal_title：Stroke

authors： Tamura A,Asano T,Sano K

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The incidence of subarachnoid hemorrhage (SAH) has been investigated in many studies. A recent study in Izumo, Japan, indicates that the incidence of SAH is as high as that in Finland. The purpose of this study was to confirm the high incidence of SAH in Japan. METHODS:The incidence rate of SAH ...

journal_title：Stroke

authors： Ohkuma H,Fujita S,Suzuki S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose of the study is to compare the reliability of the Barthel activities of daily living score, which assesses disability, with the Rankin scale, which assesses handicap, and to determine their mutual agreement. METHODS:Fifty patients with stroke of varying severity were identified by a ...

journal_title：Stroke

authors： Wolfe CD,Taub NA,Woodrow EJ,Burney PG

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:A full appreciation of the presence of cerebral vascular lesions in cognitively impaired patients can be ultimately reached at the neuropathological level. However, there are no detailed guidelines regarding what neuropathologists should look for at autopsy in cases of suspected vascular dementia...

journal_title：Stroke

authors： Pantoni L,Sarti C,Alafuzoff I,Jellinger K,Munoz DG,Ogata J,Palumbo V

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:MRI characterization of carotid plaque has been studied recently as a potential tool to predict stroke caused by carotid atherosclerosis. We performed a systematic review and meta-analysis to summarize the association of MRI-determined intraplaque hemorrhage, lipid-rich necrotic core, and thinnin...

journal_title：Stroke

authors： Gupta A,Baradaran H,Schweitzer AD,Kamel H,Pandya A,Delgado D,Dunning A,Mushlin AI,Sanelli PC

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Release of excitatory amino acids (EAA) is considered a cause of neuronal damage in ischemia. We investigated the sources and mechanisms of EAA release using microdialysis in regions of incomplete ischemia where perfusion was reduced by 50% to 80%, by applying inhibitors of volume-regulated anion...

journal_title：Stroke

authors： Feustel PJ,Jin Y,Kimelberg HK

更新日期：2004-05-01 00:00:00

abstract：:Using clinical presentation, angiography, computed tomography, and nuclear magnetic resonance imaging, 7 patients were identified who had strictly unilateral hemispheric infarction and unilateral cerebrovascular disease. In 6, cerebral blood flow measured by fluorine-18-fluoromethane inhalation and positron emission t...

journal_title：Stroke

authors： Lagrèze HL,Levine RL,Pedula KL,Nickles RJ,Sunderland JS,Rowe BR

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the cause of stroke among patients with patent foramen ovale (PFO) may be due to paradoxical cerebral embolism (PCE), this mechanism is often difficult to prove. The aim of our study was to evaluate the association between brain imaging findings suggestive of embolism and PFO among ische...

journal_title：Stroke

authors： Steiner MM,Di Tullio MR,Rundek T,Gan R,Chen X,Liguori C,Brainin M,Homma S,Sacco RL

更新日期：1998-05-01 00:00:00

abstract：:Background and Purpose- Although obesity is an established risk factor for cardiovascular disease and stroke, studies have shown evidence of an obesity paradox-a protective effect of obesity in patients who already have these disease states. Data on the obesity paradox in intracerebral hemorrhage is limited. Methods- ...

journal_title：Stroke

authors： Persaud SR,Lieber AC,Donath E,Stingone JA,Dangayach NS,Zhang X,Mocco J,Kellner CP

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The aim of our study was to clarify the pathophysiology of perioperative cerebral complications during carotid endarterectomy in our series. METHODS:By means of transcranial Doppler ultrasonography and stump pressure measurement, we monitored 112 patients who underwent carotid endarterectomy und...

journal_title：Stroke

authors： Finocchi C,Gandolfo C,Carissimi T,Del Sette M,Bertoglio C

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the efficacy of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in reducing future vascular events for patients with coronary heart disease is established, less is known about the precise benefit of these agents among patients with stroke. We evaluated whether ...

journal_title：Stroke

authors： Lee M,Saver JL,Hong KS,Hao Q,Chow J,Ovbiagele B

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We aimed to describe the frequency and characteristics of acute ischemic stroke and transient ischemic attacks presenting predominantly with amnesia (ischemic amnesia) and to identify clinical clues for differentiating them from transient global amnesia (TGA). METHODS:We retrospectively analyzed...

journal_title：Stroke

authors： Michel P,Beaud V,Eskandari A,Maeder P,Demonet JF,Eskioglou E

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Several observations indicate that, during energy deprivation, endogenous dopamine may become neurotoxic. Accordingly, the nucleus striatum is a preferential site of silent infarcts in humans, and experimental ischemia caused by homolateral carotid occlusion selectively damages this dopamine-enri...

journal_title：Stroke

authors： Saulle E,Centonze D,Martín AB,Moratalla R,Bernardi G,Calabresi P

更新日期：2002-12-01 00:00:00